Intrapulmonary pharmacokinetics and pharmacodynamics of posaconazole at steady state in healthy subjects

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 2, 2009, Pages 703-707

  Conte Jr , John E ^a,b   Golden, Jeffrey A ^b   Krishna, Gopal ^c   McIver, Marina ^a,b   Little, Emily ^a,b   Zurlinden, Elisabeth ^a,b  

^a American Health Sciences   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POSACONAZOLE;

ADULT; AREA UNDER THE CURVE; ARTICLE; ASPERGILLUS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG SAFETY; DRUG TOLERABILITY; FATIGUE; FEMALE; HEADACHE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; LIPID DIET; LIQUID CHROMATOGRAPHY; LUNG ALVEOLUS CELL; LUNG LAVAGE; MALE; MAXIMUM PLASMA CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NAUSEA; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STEADY STATE; TANDEM MASS SPECTROMETRY; UNSPECIFIED SIDE EFFECT;

ADULT; ANTIBIOTICS, ANTIFUNGAL; AREA UNDER CURVE; ASPERGILLUS; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOSCOPY; EPITHELIUM; FEMALE; HUMANS; LUNG; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; PROTEIN BINDING; PULMONARY ALVEOLI; TRIAZOLES; YOUNG ADULT;

EID: 59749086528     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00663-08     Document Type: Article

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