메뉴 건너뛰기




Volumn 37, Issue 2, 2009, Pages 254-258

Metabolism of quetiapine by CYP3A4 and CYP3A5 in presence or absence of cytochrome B5

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME B5; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DRUG METABOLITE; QUETIAPINE; SULFOXIDE;

EID: 59649128805     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.108.023291     Document Type: Article
Times cited : (60)

References (29)
  • 3
    • 17844379465 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of quetiapine: An atypical antipsychotic
    • DeVane CL and Nemeroff CB (2001) Clinical pharmacokinetics of quetiapine: an atypical antipsychotic. Clin Pharmacokinet 40:509-522.
    • (2001) Clin Pharmacokinet , vol.40 , pp. 509-522
    • DeVane, C.L.1    Nemeroff, C.B.2
  • 4
    • 0037272197 scopus 로고    scopus 로고
    • Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism: Focus on in vitro studies
    • Donato MT and Castell JV (2003) Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism: focus on in vitro studies. Clin Pharmacokinet 42:153-178.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 153-178
    • Donato, M.T.1    Castell, J.V.2
  • 5
    • 34147109227 scopus 로고    scopus 로고
    • Influence of the Cyp3a5 genotype on tacrolimus pharmacokinetics and pharmacodynamics in young kidney transplant recipients
    • Ferraresso M, Tirelli A, Ghio L, Grillo P, Martina V, Torresani E, and Edefonti A (2007) Influence of the Cyp3a5 genotype on tacrolimus pharmacokinetics and pharmacodynamics in young kidney transplant recipients. Pediatr Transplant 11:296-300.
    • (2007) Pediatr Transplant , vol.11 , pp. 296-300
    • Ferraresso, M.1    Tirelli, A.2    Ghio, L.3    Grillo, P.4    Martina, V.5    Torresani, E.6    Edefonti, A.7
  • 6
    • 0031963279 scopus 로고    scopus 로고
    • Time course of central nervous dopamine-D-2 and 5-HT2 receptor blockade and plasma drug concentrations after discontinuation of quetiapine (Seroquel (R)) in patients with schizophrenia
    • Gefvert O, Bergstriom M, Långstrom B, Lundberg T, Lindstriöm L, and Yates R (1998) Time course of central nervous dopamine-D-2 and 5-HT2 receptor blockade and plasma drug concentrations after discontinuation of quetiapine (Seroquel (R)) in patients with schizophrenia. Psychopharmacology 135:119-126.
    • (1998) Psychopharmacology , vol.135 , pp. 119-126
    • Gefvert, O.1    Bergstriom, M.2    Långstrom, B.3    Lundberg, T.4    Lindstriöm, L.5    Yates, R.6
  • 9
    • 3242779991 scopus 로고    scopus 로고
    • CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation
    • Goto M, Masuda S, Kiuchi T, Ogura Y, Oike F, Okuda M, Tanaka K, and Inui K (2004) CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation. Pharmacogenetics 14:471-478.
    • (2004) Pharmacogenetics , vol.14 , pp. 471-478
    • Goto, M.1    Masuda, S.2    Kiuchi, T.3    Ogura, Y.4    Oike, F.5    Okuda, M.6    Tanaka, K.7    Inui, K.8
  • 10
    • 33644898140 scopus 로고    scopus 로고
    • Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics
    • Grimm SW, Richtand NM, Winter HR, Stams KR, and Reele SB (2006) Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics. Br J Clin Pharmacol 61:58 -69.
    • (2006) Br J Clin Pharmacol , vol.61 , pp. 58-69
    • Grimm, S.W.1    Richtand, N.M.2    Winter, H.R.3    Stams, K.R.4    Reele, S.B.5
  • 11
    • 0001711452 scopus 로고    scopus 로고
    • In vitro prediction of potential metabolic drug interactions for Seroquel
    • Grimm SW, Stams KR, and Bui K (1997) In vitro prediction of potential metabolic drug interactions for Seroquel. Schizophr Res 24:198.
    • (1997) Schizophr Res , vol.24 , pp. 198
    • Grimm, S.W.1    Stams, K.R.2    Bui, K.3
  • 12
    • 33646006090 scopus 로고    scopus 로고
    • Evaluation of microsomal incubation conditions on CYP3A4-mediated metabolism of cyclosporine A by a statistical experimental design
    • Hermann M, Kase ET, Molden E, and Christensen H (2006) Evaluation of microsomal incubation conditions on CYP3A4-mediated metabolism of cyclosporine A by a statistical experimental design. Curr Drug Metab 7:265-271.
    • (2006) Curr Drug Metab , vol.7 , pp. 265-271
    • Hermann, M.1    Kase, E.T.2    Molden, E.3    Christensen, H.4
  • 15
    • 49549104014 scopus 로고    scopus 로고
    • N-Desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity
    • Jensen NH, Rodriguiz RM, Caron MG, Wetsel WC, Rothman RB, and Roth BL (2008) N-Desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity. Neuropsychopharmacology 33:2303-2312.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2303-2312
    • Jensen, N.H.1    Rodriguiz, R.M.2    Caron, M.G.3    Wetsel, W.C.4    Rothman, R.B.5    Roth, B.L.6
  • 16
    • 4143108324 scopus 로고    scopus 로고
    • Substrate depletion approach for determining in vitro metabolic clearance: Time dependencies in hepatocyte and microsomal incubations
    • Jones HM and Houston JB (2004) Substrate depletion approach for determining in vitro metabolic clearance: time dependencies in hepatocyte and microsomal incubations. Drug Metab Dispos 32:973-982.
    • (2004) Drug Metab Dispos , vol.32 , pp. 973-982
    • Jones, H.M.1    Houston, J.B.2
  • 17
    • 33845806096 scopus 로고    scopus 로고
    • Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects
    • Kim KA, Park PW, Lee OJ, Kang DK, and Park JY (2007) Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects. J Clin Pharmacol 47:87-93.
    • (2007) J Clin Pharmacol , vol.47 , pp. 87-93
    • Kim, K.A.1    Park, P.W.2    Lee, O.J.3    Kang, D.K.4    Park, J.Y.5
  • 19
    • 14044254164 scopus 로고    scopus 로고
    • Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes
    • Klees TM, Sheffels P, Dale O, and Kharasch ED (2005) Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes. Drug Metab Dispos 33:303-311.
    • (2005) Drug Metab Dispos , vol.33 , pp. 303-311
    • Klees, T.M.1    Sheffels, P.2    Dale, O.3    Kharasch, E.D.4
  • 21
    • 0037131879 scopus 로고    scopus 로고
    • Genetic contribution to variable human CYP3A-mediated metabolism
    • Lamba JK, Lin YS, Schuetz EG, and Thummel KE (2002) Genetic contribution to variable human CYP3A-mediated metabolism. Adv Drug Deliv Rev 54:1271-1294.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1271-1294
    • Lamba, J.K.1    Lin, Y.S.2    Schuetz, E.G.3    Thummel, K.E.4
  • 22
    • 4344664426 scopus 로고    scopus 로고
    • A liquid chromatographic-electrospray-tandem mass spectrometric method for quantitation of quetiapine in human plasma and liver microsomes: Application to study in vitro metabolism
    • Lin SN, Chang Y, Moody DE, and Foltz RL (2004) A liquid chromatographic-electrospray-tandem mass spectrometric method for quantitation of quetiapine in human plasma and liver microsomes: application to study in vitro metabolism. J Anal Toxicol 28:443-448.
    • (2004) J Anal Toxicol , vol.28 , pp. 443-448
    • Lin, S.N.1    Chang, Y.2    Moody, D.E.3    Foltz, R.L.4
  • 26
    • 0034883375 scopus 로고    scopus 로고
    • Optimizing drug development: Strategies to assess drug metabolism/transporter interaction potential-toward a consensus
    • Tucker GT, Houston JB, and Huang SM (2001) Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential-toward a consensus. Clin Pharmacol Ther 70:103-114.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 103-114
    • Tucker, G.T.1    Houston, J.B.2    Huang, S.M.3
  • 28
    • 0345016882 scopus 로고    scopus 로고
    • Effects of cytochrome b(5) on drug oxidation activities of human cytochrome P450 (CYP) 3As: Similarity of CYP3A5 with CYP3A4 but not CYP3A7
    • Yamaori S, Yamazaki H, Suzuki A, Yamada A, Tani H, Kamidate T, Fujita K, and Kamataki T (2003) Effects of cytochrome b(5) on drug oxidation activities of human cytochrome P450 (CYP) 3As: similarity of CYP3A5 with CYP3A4 but not CYP3A7. Biochem Pharmacol 66:2333-2340.
    • (2003) Biochem Pharmacol , vol.66 , pp. 2333-2340
    • Yamaori, S.1    Yamazaki, H.2    Suzuki, A.3    Yamada, A.4    Tani, H.5    Kamidate, T.6    Fujita, K.7    Kamataki, T.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.