-
2
-
-
33746051348
-
Selective metabolism of vincristine in vitro by CYP3A5
-
Dennison JB, Kulanthaivel P, Barbuch RJ, Renbarger JL, Ehlhardt WJ, and Hall SD (2006) Selective metabolism of vincristine in vitro by CYP3A5. Drug Metab Dispos 34:1317-1327.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 1317-1327
-
-
Dennison, J.B.1
Kulanthaivel, P.2
Barbuch, R.J.3
Renbarger, J.L.4
Ehlhardt, W.J.5
Hall, S.D.6
-
3
-
-
17844379465
-
Clinical pharmacokinetics of quetiapine: An atypical antipsychotic
-
DeVane CL and Nemeroff CB (2001) Clinical pharmacokinetics of quetiapine: an atypical antipsychotic. Clin Pharmacokinet 40:509-522.
-
(2001)
Clin Pharmacokinet
, vol.40
, pp. 509-522
-
-
DeVane, C.L.1
Nemeroff, C.B.2
-
4
-
-
0037272197
-
Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism: Focus on in vitro studies
-
Donato MT and Castell JV (2003) Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism: focus on in vitro studies. Clin Pharmacokinet 42:153-178.
-
(2003)
Clin Pharmacokinet
, vol.42
, pp. 153-178
-
-
Donato, M.T.1
Castell, J.V.2
-
5
-
-
34147109227
-
Influence of the Cyp3a5 genotype on tacrolimus pharmacokinetics and pharmacodynamics in young kidney transplant recipients
-
Ferraresso M, Tirelli A, Ghio L, Grillo P, Martina V, Torresani E, and Edefonti A (2007) Influence of the Cyp3a5 genotype on tacrolimus pharmacokinetics and pharmacodynamics in young kidney transplant recipients. Pediatr Transplant 11:296-300.
-
(2007)
Pediatr Transplant
, vol.11
, pp. 296-300
-
-
Ferraresso, M.1
Tirelli, A.2
Ghio, L.3
Grillo, P.4
Martina, V.5
Torresani, E.6
Edefonti, A.7
-
6
-
-
0031963279
-
Time course of central nervous dopamine-D-2 and 5-HT2 receptor blockade and plasma drug concentrations after discontinuation of quetiapine (Seroquel (R)) in patients with schizophrenia
-
Gefvert O, Bergstriom M, Långstrom B, Lundberg T, Lindstriöm L, and Yates R (1998) Time course of central nervous dopamine-D-2 and 5-HT2 receptor blockade and plasma drug concentrations after discontinuation of quetiapine (Seroquel (R)) in patients with schizophrenia. Psychopharmacology 135:119-126.
-
(1998)
Psychopharmacology
, vol.135
, pp. 119-126
-
-
Gefvert, O.1
Bergstriom, M.2
Långstrom, B.3
Lundberg, T.4
Lindstriöm, L.5
Yates, R.6
-
7
-
-
34247895481
-
Therapeutic drug monitoring of quetiapine in adolescents with psychotic disorders
-
Gerlach M, Hudie;nnerkopf R, Rothenhöfer S, Libal G, Burger R, Clement HW, Fegert JM, Wewetzer Ch, and Mehler-Wex C (2007) Therapeutic drug monitoring of quetiapine in adolescents with psychotic disorders. Pharmacopsychiatry 40:72-76.
-
(2007)
Pharmacopsychiatry
, vol.40
, pp. 72-76
-
-
Gerlach, M.1
Hudie2
nnerkopf, R.3
Rothenhöfer, S.4
Libal, G.5
Burger, R.6
Clement, H.W.7
Fegert, J.M.8
Ch, W.9
Mehler-Wex, C.10
-
8
-
-
47749142215
-
Unique mechanism of action for the antidepressant properties of the atypical antipsychotic quetiapine
-
May 17-19; San Diego, CA. Biological Psychiatry, San Diego, CA
-
Goldstein JM, Christoph G, Grimm S, Liu JW, Widzowski D, and Brecher M (2007) Unique mechanism of action for the antidepressant properties of the atypical antipsychotic quetiapine. The Society of Biological Psychiatry's 62 nd Annual Convention & Scientific Program; 2007 May 17-19; San Diego, CA. Biological Psychiatry, San Diego, CA.
-
(2007)
The Society of Biological Psychiatry's 62 nd Annual Convention & Scientific Program
-
-
Goldstein, J.M.1
Christoph, G.2
Grimm, S.3
Liu, J.W.4
Widzowski, D.5
Brecher, M.6
-
9
-
-
3242779991
-
CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation
-
Goto M, Masuda S, Kiuchi T, Ogura Y, Oike F, Okuda M, Tanaka K, and Inui K (2004) CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation. Pharmacogenetics 14:471-478.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 471-478
-
-
Goto, M.1
Masuda, S.2
Kiuchi, T.3
Ogura, Y.4
Oike, F.5
Okuda, M.6
Tanaka, K.7
Inui, K.8
-
10
-
-
33644898140
-
Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics
-
Grimm SW, Richtand NM, Winter HR, Stams KR, and Reele SB (2006) Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics. Br J Clin Pharmacol 61:58 -69.
-
(2006)
Br J Clin Pharmacol
, vol.61
, pp. 58-69
-
-
Grimm, S.W.1
Richtand, N.M.2
Winter, H.R.3
Stams, K.R.4
Reele, S.B.5
-
11
-
-
0001711452
-
In vitro prediction of potential metabolic drug interactions for Seroquel
-
Grimm SW, Stams KR, and Bui K (1997) In vitro prediction of potential metabolic drug interactions for Seroquel. Schizophr Res 24:198.
-
(1997)
Schizophr Res
, vol.24
, pp. 198
-
-
Grimm, S.W.1
Stams, K.R.2
Bui, K.3
-
12
-
-
33646006090
-
Evaluation of microsomal incubation conditions on CYP3A4-mediated metabolism of cyclosporine A by a statistical experimental design
-
Hermann M, Kase ET, Molden E, and Christensen H (2006) Evaluation of microsomal incubation conditions on CYP3A4-mediated metabolism of cyclosporine A by a statistical experimental design. Curr Drug Metab 7:265-271.
-
(2006)
Curr Drug Metab
, vol.7
, pp. 265-271
-
-
Hermann, M.1
Kase, E.T.2
Molden, E.3
Christensen, H.4
-
13
-
-
0041831261
-
Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus
-
Hesselink DA, van Schaik RH, van der Heiden IP, van der Werf M, Gregoor PJ, Lindemans J, Weimar W, and van Gelder T (2003) Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus. Clin Pharmacol Ther 74:245-254.
-
(2003)
Clin Pharmacol Ther
, vol.74
, pp. 245-254
-
-
Hesselink, D.A.1
van Schaik, R.H.2
van der Heiden, I.P.3
van der Werf, M.4
Gregoor, P.J.5
Lindemans, J.6
Weimar, W.7
van Gelder, T.8
-
14
-
-
9444228347
-
Evidence of significant contribution from CYP3A5 to hepatic drug metabolism
-
Huang W, Lin YS, McConn DJ 2nd, Calamia JC, Totah RA, Isoherranen N, Glodowski M, and Thummel KE (2004) Evidence of significant contribution from CYP3A5 to hepatic drug metabolism. Drug Metab Dispos 32:1434-1445.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 1434-1445
-
-
Huang, W.1
Lin, Y.S.2
McConn 2nd, D.J.3
Calamia, J.C.4
Totah, R.A.5
Isoherranen, N.6
Glodowski, M.7
Thummel, K.E.8
-
15
-
-
49549104014
-
N-Desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity
-
Jensen NH, Rodriguiz RM, Caron MG, Wetsel WC, Rothman RB, and Roth BL (2008) N-Desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity. Neuropsychopharmacology 33:2303-2312.
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 2303-2312
-
-
Jensen, N.H.1
Rodriguiz, R.M.2
Caron, M.G.3
Wetsel, W.C.4
Rothman, R.B.5
Roth, B.L.6
-
16
-
-
4143108324
-
Substrate depletion approach for determining in vitro metabolic clearance: Time dependencies in hepatocyte and microsomal incubations
-
Jones HM and Houston JB (2004) Substrate depletion approach for determining in vitro metabolic clearance: time dependencies in hepatocyte and microsomal incubations. Drug Metab Dispos 32:973-982.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 973-982
-
-
Jones, H.M.1
Houston, J.B.2
-
17
-
-
33845806096
-
Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects
-
Kim KA, Park PW, Lee OJ, Kang DK, and Park JY (2007) Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects. J Clin Pharmacol 47:87-93.
-
(2007)
J Clin Pharmacol
, vol.47
, pp. 87-93
-
-
Kim, K.A.1
Park, P.W.2
Lee, O.J.3
Kang, D.K.4
Park, J.Y.5
-
18
-
-
4143049054
-
Lipid-lowering response to statins is affected by CYP3A5 polymorphism
-
Kivistö KT, Niemi M, Schaeffeler E, Pitkälä K, Tilvis R, Fromm MF, Schwab M, Eichelbaum M, and Strandberg T (2004) Lipid-lowering response to statins is affected by CYP3A5 polymorphism. Pharmacogenetics 14:523-525.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 523-525
-
-
Kivistö, K.T.1
Niemi, M.2
Schaeffeler, E.3
Pitkälä, K.4
Tilvis, R.5
Fromm, M.F.6
Schwab, M.7
Eichelbaum, M.8
Strandberg, T.9
-
20
-
-
0035071598
-
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J, Watkins PB, Daly A, Wrighton SA, Hall SD, et al. (2001) Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet 27:383-391.
-
(2001)
Nat Genet
, vol.27
, pp. 383-391
-
-
Kuehl, P.1
Zhang, J.2
Lin, Y.3
Lamba, J.4
Assem, M.5
Schuetz, J.6
Watkins, P.B.7
Daly, A.8
Wrighton, S.A.9
Hall, S.D.10
-
22
-
-
4344664426
-
A liquid chromatographic-electrospray-tandem mass spectrometric method for quantitation of quetiapine in human plasma and liver microsomes: Application to study in vitro metabolism
-
Lin SN, Chang Y, Moody DE, and Foltz RL (2004) A liquid chromatographic-electrospray-tandem mass spectrometric method for quantitation of quetiapine in human plasma and liver microsomes: application to study in vitro metabolism. J Anal Toxicol 28:443-448.
-
(2004)
J Anal Toxicol
, vol.28
, pp. 443-448
-
-
Lin, S.N.1
Chang, Y.2
Moody, D.E.3
Foltz, R.L.4
-
23
-
-
0036089341
-
Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism
-
Lin YS, Dowling AL, Quigley SD, Farm FM, Zhang J, Lamba J, Schuetz EG, and Thummel KE (2002) Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism. Mol Pharmacol 62:162-172.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 162-172
-
-
Lin, Y.S.1
Dowling, A.L.2
Quigley, S.D.3
Farm, F.M.4
Zhang, J.5
Lamba, J.6
Schuetz, E.G.7
Thummel, K.E.8
-
24
-
-
34250825926
-
A preclinical and clinical rationale for quetiapine in mood syndromes
-
Mclntyre RS, Soczynska JK, Woldeyohannes HO, Alsuwaidan M, and Konarski JZ (2007) A preclinical and clinical rationale for quetiapine in mood syndromes. Expert Opin Pharmaco- ther 8:1211-1219.
-
(2007)
Expert Opin Pharmaco- ther
, vol.8
, pp. 1211-1219
-
-
Mclntyre, R.S.1
Soczynska, J.K.2
Woldeyohannes, H.O.3
Alsuwaidan, M.4
Konarski, J.Z.5
-
25
-
-
0030812885
-
In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s
-
Prueksaritanont T, Gorham LM, Ma B, Liu L, Yu X, Zhao JJ, Slaughter DE, Arison BH, and Vyas KP (1997) In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s. Drug Metab Dispos 25:1191-1199.
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 1191-1199
-
-
Prueksaritanont, T.1
Gorham, L.M.2
Ma, B.3
Liu, L.4
Yu, X.5
Zhao, J.J.6
Slaughter, D.E.7
Arison, B.H.8
Vyas, K.P.9
-
26
-
-
0034883375
-
Optimizing drug development: Strategies to assess drug metabolism/transporter interaction potential-toward a consensus
-
Tucker GT, Houston JB, and Huang SM (2001) Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential-toward a consensus. Clin Pharmacol Ther 70:103-114.
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 103-114
-
-
Tucker, G.T.1
Houston, J.B.2
Huang, S.M.3
-
27
-
-
0037518214
-
Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism
-
Westlind-Johnsson A, Malmebo S, Johansson A, Otter C, Andersson TB, Johansson I, Edwards RJ, Boobis AR, and Ingelman-Sundberg M (2003) Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism. Drug Metab Dispos 31:755-761.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 755-761
-
-
Westlind-Johnsson, A.1
Malmebo, S.2
Johansson, A.3
Otter, C.4
Andersson, T.B.5
Johansson, I.6
Edwards, R.J.7
Boobis, A.R.8
Ingelman-Sundberg, M.9
-
28
-
-
0345016882
-
Effects of cytochrome b(5) on drug oxidation activities of human cytochrome P450 (CYP) 3As: Similarity of CYP3A5 with CYP3A4 but not CYP3A7
-
Yamaori S, Yamazaki H, Suzuki A, Yamada A, Tani H, Kamidate T, Fujita K, and Kamataki T (2003) Effects of cytochrome b(5) on drug oxidation activities of human cytochrome P450 (CYP) 3As: similarity of CYP3A5 with CYP3A4 but not CYP3A7. Biochem Pharmacol 66:2333-2340.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 2333-2340
-
-
Yamaori, S.1
Yamazaki, H.2
Suzuki, A.3
Yamada, A.4
Tani, H.5
Kamidate, T.6
Fujita, K.7
Kamataki, T.8
-
29
-
-
0037693831
-
Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms
-
Zheng H, Webber S, Zeevi A, Schuetz E, Zhang J, Bowman P, Boyle G, Law Y, Miller S, Lamba J, et al. (2003) Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms. Am J Transplant 3:477-483.
-
(2003)
Am J Transplant
, vol.3
, pp. 477-483
-
-
Zheng, H.1
Webber, S.2
Zeevi, A.3
Schuetz, E.4
Zhang, J.5
Bowman, P.6
Boyle, G.7
Law, Y.8
Miller, S.9
Lamba, J.10
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