Single Photon Emission Computed Tomography-Based Three-Dimensional Conformal Radiotherapy for Hepatocellular Carcinoma With Portal Vein Tumor Thrombus

International Journal of Radiation Oncology Biology Physics

Volumn 73, Issue 3, 2009, Pages 824-831

  Shirai, Shintaro ^a   Sato, Morio ^a   Suwa, Kazuhiro ^a   Kishi, Kazushi ^a   Shimono, Chigusa ^a   Kawai, Nobuyuki ^a   Tanihata, Hirohiko ^a   Minamiguchi, Hiroki ^a   Nakai, Motoki ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Functional image guided radiotherapy; Hepatocellular carcinoma; Portal vein tumor thrombus; Tc 99m galactosyl human serum albumin; Three dimensional conformal radiotherapy

Indexed keywords

ANIMAL CELL CULTURE; BODY FLUIDS; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC RADIOGRAPHY; FLUORESCENT SCREENS; LIVER; MEDICAL IMAGING; PARTICLE BEAMS; PHOTONS; RADIOTHERAPY; TECHNETIUM; TELEVISION PICTURE TUBES; THREE DIMENSIONAL; TOMOGRAPHY; TUMORS;

FUNCTIONAL IMAGE-GUIDED RADIOTHERAPY; HEPATOCELLULAR CARCINOMA; PORTAL VEIN TUMOR THROMBUS; TC-99M-GALACTOSYL HUMAN SERUM ALBUMIN; THREE-DIMENSIONAL CONFORMAL RADIOTHERAPY;

SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY;

ALKALINE PHOSPHATASE; RADIOPHARMACEUTICAL AGENT; TECHNETIUM GALACTOSYL HUMAN SERUM ALBUMIN 99M; UNCLASSIFIED DRUG;

ADULT; AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; CANCER RADIOTHERAPY; CLINICAL ARTICLE; COMPUTER ASSISTED RADIOTHERAPY; DISEASE COURSE; DISEASE FREE SURVIVAL; FEMALE; GASTROINTESTINAL TOXICITY; HUMAN; HYPERBILIRUBINEMIA; HYPOALBUMINEMIA; LEUKOPENIA; LIVER CELL CARCINOMA; LIVER FUNCTION; MALE; PORTAL VEIN THROMBOSIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIATION DOSE; RADIATION FIELD; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THROMBOCYTOPENIA; TREATMENT PLANNING; TUMOR LOCALIZATION; TUMOR THROMBUS; TUMOR VOLUME;

AGED; AGED, 80 AND OVER; CARCINOMA, HEPATOCELLULAR; CHEMOEMBOLIZATION, THERAPEUTIC; FEMALE; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; PORTAL VEIN; PROSPECTIVE STUDIES; RADIOPHARMACEUTICALS; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; SURVIVAL RATE; TECHNETIUM TC 99M AGGREGATED ALBUMIN; TECHNETIUM TC 99M PENTETATE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TUMOR BURDEN; VENOUS THROMBOSIS;

EID: 59649126661     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.04.055     Document Type: Article

References (17)

1. Dawson L.A., Normolle D., Balter J.M., et al. Analysis of radiation-induced liver disease using the Lyman NTCP model. Int J Radiat Oncol Biol Phys 53 (2002) 810-821
2. Ishikura S., Ogino T., Furuse J., et al. Radiotherapy after transcatheter arterial chemoembolization for patients with hepatocellular carcinoma and portal vein tumor thrombus. Am J Clin Oncol 25 (2002) 189-193
3. Yamada K., Izaki K., Sugimoto K., et al. Prospective trial of combined transcatheter arterial chemoembolization and three-dimensional conformal radiotherapy for portal vein tumor thrombus in patients with unresectable hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 57 (2003) 113-119
4. Tazawa J., Maeda M., Sakai Y., et al. Radiation therapy in combination with transcatheter arterial chemoembolization for hepatocellular carcinoma with extensive portal vein involvement. J Gastroenterol Hepatol 16 (2001) 660-665
5. Shimada M., Takenaka K., Kawahara N., et al. Surgical treatment strategy for patients with Stage 4 hepatocellular carcinoma. Surgery 119 (1996) 517-522
6. Ikai I., Yamaoka Y., Yamamoto Y., et al. Surgical intervention for patients with Stage 4-A hepatocellular carcinoma without lymph nodes metastasis. Proposal as a standard therapy. Ann Surg 227 (1998) 433-439
7. Xu Z.Y., Liang S.X., Zhu J., et al. Prediction of radiation-induced liver disease by Lyman normal-tissue complication probability model in three-dimensional conformal radiation therapy for primary liver carcinoma. Int J Radiat Oncol Biol Phys 65 (2006) 189-195
8. Cheng J.C.H., Wu J.K., Huang C.M., et al. Radiation-induced liver disease after three-dimensional conformal radiotherapy for patients with hepatocellular carcinoma: Dosimetric analysis and implication. Int J Radiat Oncol Biol Phys 54 (2002) 156-162
9. Sawamura T., Nakada H., Hazama H., et al. Hyperasialoglycoproteinemia in patients with chronic liver disease and/or liver cell carcinoma. Gastroenterology 87 (1984) 1217-1221
10. Ha-Kawa S.K., and Tanaka Y. A quantitative model of technetium-99m-DTPA-galactosyl-HSA for the assessment of hepatic blood flow and hepatic binding receptor. J Nucl Med 32 (1991) 2233-2240
11. Kudo M., Toda A., Ikekubo K., et al. Quantitative assessment of hepatocellular function through in vivo radioreceptor imaging with technetium-99m-galactosyl-human serum albumin (TcGSA). Hepatology 17 (1993) 814-819
12. Emami B., Lyman J., Brown A., et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 21 (1991) 109-122
13. Park W., Lim D.H., Paik S.W., et al. Local radiotherapy for patients with unresectable hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 61 (2005) 1143-1150
14. Park H.C., Seong J., Han K.H., et al. Dose-response relationship in local radiotherapy for hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 54 (2002) 150-155
15. Ciernik I.F., Huser M., Burger C., et al. Automated functional image-guided radiation treatment planning for rectal cancer. Int J Radiat Oncol Biol Phys 62 (2005) 893-900
16. Wang D., Schultz C.J., Jursinic P.A., et al. Initial experience of FDG-PET/CT guided IMRT of head-and-neck carcinoma. Int J Radiat Oncol Biol Phys 65 (2006) 143-151
17. Madani I., Duthoy W., Derie C., et al. Positron emission tomography-guided, focal-dose escalation using intensity-modulated radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys 68 (2007) 126-135