The preconditioning effect of sevoflurane on the oxygen glucose-deprived hippocampal slice: The role of tyrosine kinases and duration of ischemia

Anesthesia and Analgesia

Volumn 108, Issue 2, 2009, Pages 601-608

  Sigaut, Stéphanie ^a,b   Jannier, Virginie ^a   Rouelle, Danielle ^b   Gressens, Pierre ^b   Mantz, Jean ^a,b   Dahmani, Souhayl ^a,b  

^a BEAUJON HOSPITAL   (France)

^b HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CASPASE 3; FOCAL ADHESION KINASE; GLUCOSE; OXYGEN; PROPIDIUM IODIDE; PROTEIN TYROSINE KINASE; SEVOFLURANE; ACTIN; ETHER DERIVATIVE; INHALATION ANESTHETIC AGENT; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; BRAIN PERFUSION; BRAIN TISSUE; CONTROLLED STUDY; DISEASE DURATION; DRUG EFFECT; FLUORESCENCE; HIPPOCAMPUS; IMMUNOBLOTTING; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; BLOOD GAS ANALYSIS; BRAIN CIRCULATION; BRAIN HYPOXIA; CELL DEATH; ENZYMOLOGY; METABOLISM; PATHOPHYSIOLOGY; PH; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; VASCULARIZATION;

ACTINS; ANESTHETICS, INHALATION; ANIMALS; BLOOD GAS ANALYSIS; BRAIN ISCHEMIA; CASPASE 3; CELL DEATH; CEREBROVASCULAR CIRCULATION; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GLUCOSE; HIPPOCAMPUS; HYDROGEN-ION CONCENTRATION; HYPOXIA, BRAIN; MALE; METHYL ETHERS; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 59649105979     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e31818e2018     Document Type: Article

References (30)

1. Warner DS, McFarlane C, Todd MM, Ludwig P, McAllister AM. Sevoflurane and halothane reduce focal ischemic brain damage in the rat. Possible influence on thermoregulation. Anesthesiology 1993;79:985-92
2. Werner C, Mollenberg O, Kochs E, Schulte J am Esch. Sevoflurane improves neurological outcome after incomplete cerebral ischaemia in rats. Br J Anaesth 1995;75:756-60
3. Toner CC, Connelly K, Whelpton R, Bains S, Michael-Titus AT, McLaughlin DP, Stamford JA. Effects of sevoflurane on dopamine, glutamate and aspartate release in an in vitro model of cerebral ischaemia. Br J Anaesth 2001;86:550-4
4. Englelhard K, Werner C, Hoffman WE, Matthes B, Blobner M, Kochs E. The effect of sevoflurane and propofol on cerebral neurotransmitter concentrations during cerebral ischemia in rats. Anesth Analg 2003;97:1155-61
5. Lei B, Popp S, Capuano-Waters C, Cottrell JE, Kass IS. Sevoflurane preconditioning protects rat hippocampus against ischemic neuronal damage. J Neurosurg Anesthesiol 2006;18:286-7
6. Wang J, Lei B, Popp S, Meng F, Cottrell JE, Kass IS. Sevoflurane immediate preconditioning alters hypoxic membrane potential changes in rat hippocampal slices and improves recovery of CA1 pyramidal cells after hypoxia and global cerebral ischemia. Neuroscience 2007;145:1097-107
7. Kawaguchi M, Kimbro JR, Drummond JC, Cole DJ, Kelly PJ, Patel PM. Isoflurane delays but does not prevent cerebral infarction in rats subjected to focal ischemia. Anesthesiology 2000;92:1335-42
8. Pape M, Englelhard K, Eberspacher E, Hollweck R, Kellermann K, Zintner S, Hutzler P, Werner C. The long-term effect of sevoflurane on neuronal cell damage and expression of apoptotic factors after cerebral ischemia and reperfusion in rats. Anesth Analg 2006;103:173-9
9. Dahmani S, Tesniere A, Rouelle D, Toutant M, Desmonts JM, Mantz J. Effects of anesthetic agents on focal adhesion kinase (pp125FAK) tyrosine phosphorylation in rat hippocampal slices. Anesthesiology 2004;101:344-53
10. Dahmani S, Rouelle D, Gressens P, Mantz J. Effects of dexmedetomidine on hippocampal focal adhesion kinase tyrosine phosphorylation in physiologic and ischemic conditions. Anesthesiology 2005;103:969-77
11. Dahmani S, Rouelle D, Gressens P, Mantz J. The effects of lidocaine and bupivacaine on protein expression of cleaved caspase 3 and tyrosine phosphorylation in the rat hippocampal slice. Anesth Analg 2007;104:119-23
12. Laake JH, Haug FM, Wieloch T, Ottersen OP. A simple in vitro model of ischemia based on hippocampal slice cultures and propidium iodide fluorescence. Brain Res Brain Res Protoc 1999;4:173-84
13. Popovic R, Liniger R, Bickler PE. Anesthetics and mild hypothermia similarly prevent hippocampal neuron death in an in vitro model of cerebral ischemia. Anesthesiology 2000;92:1343-9
14. Zhan X, Fahlman CS, Bickler PE. Isoflurane neuroprotection in rat hippocampal slices decreases with aging: changes in intracellular Ca2- regulation and N-methyl-d-aspartate receptormediated Ca2- influx. Anesthesiology 2006;104:995-1003
15. Xie Z, Dong Y, Maeda U, Alfille P, Culley DJ, Crosby G, Tanzi RE. The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels. Anesthesiology 2006;104:988-94
16. Elsersy H, Mixco J, Sheng H, Pearlstein RD, Warner DS. Selective gamma-aminobutyric acid type A receptor antagonism reverses isoflurane ischemic neuroprotection. Anesthesiology 2006;105:81-90
17. Wang L, Traystman RJ, Murphy SJ. Inhalational anesthetics as preconditioning agents in ischemic brain. Curr Opin Pharmacol 2008;8:104-10
18. Kitano H, Kirsch JR, Hurn PD, Murphy SJ. Inhalational anesthetics as neuroprotectants or chemical preconditioning agents in ischemic brain. J Cereb Blood Flow Metab 2007;27:1108-28
19. Girault JA, Costa A, Derkinderen P, Studler JM, Toutant M. FAK and PYK2/CAKbeta in the nervous system: a link between neuronal activity, plasticity and survival? Trends Neurosci 1999;22:257-63
20. Kevin LG, Novalija E, Riess ML, Camara AK, Rhodes SS, Stowe DF. Sevoflurane exposure generates superoxide but leads to decreased superoxide during ischemia and reperfusion in isolated hearts. Anesth Analg 2003;96:949 -55, table of contents
21. Vepa S, Scribner WM, Parinandi NL, English D, Garcia JG, Natarajan V. Hydrogen peroxide stimulates tyrosine phosphorylation of focal adhesion kinase in vascular endothelial cells. Am J Physiol 1999;277:L150-L158
22. Hao Q, Rutherford SA, Low B, Tang H. Suppression of the phosphorylation of receptor tyrosine phosphatase-alpha on the Src-independent site tyrosine 789 by reactive oxygen species. Mol Pharmacol 2006;69:1938-44
23. Seo JH, Ahn Y, Lee SR, Yeol Yeo C, Chung Hur K. The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway. Mol Biol Cell 2005;16:348-57
24. Bickler PE, Zhan X, Fahlman CS. Isoflurane preconditions hippocampal neurons against oxygen-glucose deprivation: role of intracellular Ca2- and mitogen-activated protein kinase signaling. Anesthesiology 2005;103:532-9
25. Larsen M, Haugstad TS, Berg-Johnsen J, Langmoen IA. The effect of isoflurane on brain amino acid release and tissue content induced by energy deprivation. J Neurosurg Anesthesiol 1998;10:166-70
26. Kass IS, Amorim P, Chambers G, Austin D, Cottrell JE. The effect of isoflurane on biochemical changes during and electrophysiological recovery after anoxia in rat hippocampal slices. J Neurosurg Anesthesiol 1997;9:280-6
27. Patel P. No magic bullets: the ephemeral nature of anestheticmediated neuroprotection. Anesthesiology 2004;100:1049-51
28. Sullivan BL, Leu D, Taylor DM, Fahlman CS, Bickler PE. Isoflurane prevents delayed cell death in an organotypic slice culture model of cerebral ischemia. Anesthesiology 2002; 96:189-95
29. Feiner JR, Bickler PE, Estrada S, Donohoe PH, Fahlman CS, Schuyler JA. Mild hypothermia, but not propofol, is neuroprotective in organotypic hippocampal cultures. Anesth Analg 2005;100:215-25
30. Gebhardt C, Heinemann U. Anoxic decrease in potassium outward currents of hippocampal cultured neurons in absence and presence of dithionite. Brain Res 1999;837:270-6