Anoxic decrease in potassium outward currents of hippocampal cultured neurons in absence and presence of dithionite

Brain Research

Volumn 837, Issue 1-2, 1999, Pages 270-276

  Gebhardt, C ^a   Heinemann, U ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Hippocampal neurons; Hydrosulphite; Hypoxia; Oxygen measurements; Potassium currents

Indexed keywords

DITHIONITE;

ANIMAL CELL; ARTICLE; BRAIN HYPOXIA; BRAIN OXYGEN CONSUMPTION; HIPPOCAMPUS; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT;

EID: 0033533179     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01616-9     Document Type: Article

References (30)

1. Archer S.L., Hampl V., Nelson D.P., Sidney E., Peterson D.A., Weir E.K. Dithionite increases radical formation and decreases vasoconstriction in the lung. Evidence that dithionite does not mimic alveolar hypoxia. Circ. Res. 77:1995;174-181.
2. 2 sensor in rat pulmonary vasculature. Circ. Res. 73:1993;1100-1112.
3. 2 deprivation. J. Neurosci. Methods. 46:1993;183-189.
4. Cummins T.R., Donnelly D.F., Haddad G.G. Effect of metabolic inhibition on the excitability of isolated hippocampal CA1 neurons: developmental aspects. J. Neurophysiol. 66:1991;1471-1482.
5. Dixon M. The acceptor specificity of flavins and flavoproteins: I. Techniques for anaerobic spectrophotometry. Biochim. Biophys. Acta. 226:1971;241-258.
6. + currents in interferon-gamma-activated microglia. Neurosci. Lett. 206:1996;101-104.
7. Evans M.S., Collings M.A., Brewer G.J. Electrophysiology of embryonic, adult and aged rat hippocampal neurons in serum free culture. J. Neurosci. Methods. 79:1998;37-46.
8. Ficker E., Heinemann U. Slow and fast transient potassium currents in cultured rat hippocampal cells. J. Physiol. (London). 445:1992;431-455.
9. Friedman J.E., Haddad G.G. Anoxia induces an increase in intracellular sodium in rat central neurons in vitro. Brain Res. 663:1994;329-334.
10. Fujimura N., Tanaka E., Yamamoto S., Shigemori M., Higashi H. Contribution of ATP-sensitive potassium channels to hypoxic hyperpolarization in rat hippocampal CA1 neurons in vitro. J. Neurophysiol. 77:1997;378-385.
11. Fujiwara N., Higashi H., Shimoji K., Yoshimura M. Effects of hypoxia on rat hippocampal neurones in vitro. J. Physiol. (London). 384:1987;131-151.
12. Glimm H., Ficker E., Heinemann U. Electrophysiological properties of neurones in cultures from postnatal rat dentate gyrus. Exp. Brain Res. 107:1996;367-381.
13. 2 deprivation in the central nervous system: on mechanisms of neuronal response, differential sensitivity and injury. Prog. Neurobiol. 40:1993;277-318.
14. Haddad G.G., Jiang C. Mechanisms of anoxia-induced depolarization in brainstem neurons: in vitro current and voltage clamp studies in the adult rat. Brain Res. 625:1993;261-268.
15. 2 tension in adult and neonatal brain slices under several experimental conditions. Brain Res. 568:1991;159-164.
16. + current in central neurons. Brain Res. 614:1993;352-356.
17. + channel independently of cytosolic factors in rat central neurons. J. Physiol. (London). 481:1994;15-26.
18. Krnjevic K., Leblond J. Changes in membrane currents of hippocampal neurons evoked by brief anoxia. J. Neurophysiol. 62:1989;15-30.
19. Lambeth D.O., Palmer G. The kinetics and mechanism of reduction of electron transfer proteins and other compounds of biological interest by dithionite. J. Biol. Chem. 248:1973;6095-6103.
20. Leblond J., Krnjevic K. Hypoxic changes in hippocampal neurons. J. Neurophysiol. 62:1989;1-14.
21. Lo L.W., Koch C.J., Wilson D.F. Calibration of oxygen-dependent quenching of the phosphorescence of Pd-meso-tetra (4-carboxyphenyl) porphine: a phosphor with general application for measuring oxygen concentration in biological systems. Anal. Biochem. 236:1996;153-160.
22. Lopez Barneo J., Ortega Saenz P., Molina A., Franco Obregon A., Urena J., Castellano A. Oxygen sensing by ion channels. Kidney Int. 51:1997;454-461.
23. Numann R.E., Wadman W.J., Wong R.K. Outward currents of single hippocampal cells obtained from the adult guinea-pig. J. Physiol. (London). 393:1987;331-353.
24. Ruppersberg J.P., Stocker M., Pongs O., Heinemann S.H., Frank R., Koenen M. Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation. Nature. 352:1991;711-714.
25. + conductance of rat axons by cytoplasmic acidification. J. Physiol. (London). 465:1993;679-697.
26. Stern M.D., Silverman H.S., Houser S.R., Josephson R.A., Capogrossi M.C., Nichols C.G., Lederer W.J., Kakatta E.G. Anoxic contractile failure in rat heart myocytes is caused by failure of intracellular calcium release due to alteration of the action potential. Proc. Natl. Acad. Sci. U.S.A. 85:1988;6954-6958.
27. + outward current in isolated ventricular heart cells of the mouse. Pfluegers Arch. 427:1994;547-549.
28. Vanderkooi J.M., Maniara G., Green T.J., Wilson D.F. An optical method for measurement of dioxygen concentration based upon quenching of phosphorescence. J. Biol. Chem. 262:1987;5476-5482.
29. Yamamoto S., Tanaka E., Higashi H. Mediation by intracellular calcium-dependent signals of hypoxic hyperpolarization in rat hippocampal CA1 neurons in vitro. J. Neurophysiol. 77:1997;386-392.
30. Yuan X.J., Goldman W.F., Tod M.L., Rubin L.J., Blaustein M.P. Hypoxia reduces potassium currents in cultured rat pulmonary but not mesenteric arterial myocytes. Am. J. Physiol. 264:1993;L116-L123.