Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population

Arthritis and Rheumatism

Volumn 60, Issue 2, 2009, Pages 553-558

  Ito, Ikue ^a   Kawasaki, Aya ^a   Ito, Satoshi ^a   Hayashi, Taichi ^a   Goto, Daisuke ^a   Matsumoto, Isao ^a   Tsutsumi, Akito ^a   Hom, Geoffrey ^c   Graham, Robert R ^c   Takasaki, Yoshinari ^d   Hashimoto, Hiroshi ^d   Ohashi, Jun ^e   Behrens, Timothy W ^c   Sumida, Takayuki ^b   Tsuchiya, Naoyuki ^b  

^a KAWASAKI MUNICIPAL HOSPITAL   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c GENENTECH INC   (United States)

^d JUNTENDO UNIVERSITY   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BLK; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; JAPANESE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS;

ASIAN CONTINENTAL ANCESTRY GROUP; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; JAPAN; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SRC-FAMILY KINASES;

EID: 59649104460     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24246     Document Type: Article

References (15)

1. Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, et al. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 2008;28:358:956-61.
2. International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), Harley JB, Alarcon-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 2008;40:204-10.
3. Dymecki SM, Zwollo P, Zeller K, Kuhajda FP, Desiderio SV. Structure and developmental regulation of the B-lymphoid tyrosine kinase gene blk. J Biol Chem 1992;267:4815-23.
4. Hochberg MC, for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997;40:1725.
5. Schildkraut JM. Examining complex genetic interactions. In: Haines JL, Pericak-Vance MA, editors. Approach to gene mapping in complex human diseases. New York: Wiley-Liss; 1998. p. 379-410.
6. Ohashi J, Yamamoto S, Tsuchiya N, Hatta Y, Komata T, Matsushita M, et al. Comparison of statistical power between 2x2 allele frequency and allele positivity tables in case-control studies of complex disease genes. Ann Hum Genet 2001;65:197-206.
7. Hashimoto H, Nishimura Y, Dong RP, Kimura A, Sasazuki T, Yamanaka K, et al. HLA antigens in Japanese patients with systemic lupus erythematosus. Scand J Rheumatol 1994;23:191-6.
8. Kyogoku C, Dijstelbloem HM, Tsuchiya N, Hatta Y, Kato H, Yamaguchi A, et al. Fc receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility. Arthritis Rheum 2002;46:1242-54.
9. Chen JY, Wang CM, Ma CC, Luo SF, Edberg JC, Kimberly RP, et al. Association of a transmembrane polymorphism of Fcγ receptor IIb (FCGR2B) with systemic lupus erythematosus in Taiwanese patients. Arthritis Rheum 2006;54:3908-17.
10. Komata T, Tsuchiya N, Matsushita M, Hagiwara K, Tokunaga K. Association of tumor necrosis factor receptor 2 (TNFR2) polymorphism with susceptibility to systemic lupus erythematosus. Tissue Antigens 1999;53:527-33.
11. Horiuchi T, Kiyohara C, Tsukamoto H, Sawabe T, Furugo I, Yoshizawa S, et al. A functional M196R polymorphism of tumour necrosis factor receptor type 2 is associated with systemic lupus erythematosus: a case-control study and a meta-analysis. Ann Rheum Dis 2007;66:320-4.
12. Kawasaki A, Tsuchiya N, Ohashi J, Murakami Y, Fukazawa T, Kusaoi M, et al. Role of APRIL (TNFSF13) polymorphisms in the susceptibility to systemic lupus erythematosus in Japanese. Rheumatology (Oxford) 2007;46:776-82.
13. Koyama T, Tsukamoto H, Masumoto K, Himeji D, Hayashi K, Harada M, et al. A novel polymorphism of the human APRIL gene is associated with systemic lupus erythematosus. Rheumatology (Oxford) 2003;42:980-5.
14. Kawasaki A, Kyogoku C, Ohashi J, Miyashita R, Hikami K, Kusaoi M, et al. Association of IRF5 polymorphisms with systemic lupus erythematosus in a Japanese population: support for a crucial role of intron 1 polymorphisms. Arthritis Rheum 2008;58:826-34.
15. Tahira T, Masumoto M, Kukita Y, Horiuchi T, Hayashi K. Pooling-based genomewide association study identifies loci for systemic lupus erythematosus [abstract]. Presented at the 57th Annual Meeting of the American Society of Human Genetics; 2007 Oct 24-7; San Diego, California. URL: http://www.ashg.org/ cgi-bin/ashg07s/ashg07.