Enamel matrix derivative versus bioactive ceramic filler in the treatment of intrabony defects: 12-Month results

Journal of Periodontology

Volumn 80, Issue 2, 2009, Pages 219-227

  Leknes, Knut N ^a   Andersen, Kari Mette ^a   Bøe, Olav E ^a   Skavland, Ragnfrid J ^a   Albandar, Jasim M ^b  

^a UNIVERSITY OF BERGEN   (Norway)

^b TEMPLE UNIVERSITY   (United States)

Author keywords

Bone regeneration; Ceramics; Enamel matrix derivative; Human studies

Indexed keywords

BIOGLASS; ENAMEL MATRIX PROTEINS; ENAMEL PROTEIN;

ADULT; AGED; ARTICLE; BONE PROSTHESIS; BONE REGENERATION; CERAMICS; CHRONIC PERIODONTITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; GINGIVA DISEASE; HUMAN; MALE; MIDDLE AGED; OSTEOLYSIS; PERIODONTAL DISEASE; PERIODONTITIS; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; REGRESSION ANALYSIS;

ADULT; AGED; ALVEOLAR BONE LOSS; BONE REGENERATION; BONE SUBSTITUTES; CERAMICS; CHRONIC PERIODONTITIS; DENTAL ENAMEL PROTEINS; DOUBLE-BLIND METHOD; FEMALE; GINGIVAL RECESSION; HUMANS; MALE; MIDDLE AGED; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL POCKET; PROSPECTIVE STUDIES; REGRESSION ANALYSIS;

EID: 59649093900     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2009.080236     Document Type: Article

References (45)

1. Papapanou PN, Wennström JL. The angular bony defect as indicator of further alveolar bone loss. J Clin Periodontol 1991;18:317-322.
2. Claffey N, Egelberg J. Clinical indicators of probing attachment loss following initial periodontal treatment in advanced periodontitis patients. J Clin Periodontol 1995;22:690-696.
3. Armitage GC. Periodontal diseases: Diagnosis. Ann Periodontol 1996;1:37-215.
4. Schwartz Z, Carnes DL Jr., Pulliam R, et al. Porcine fetal enamel matrix derivative stimulates proliferation but not differentiation of pre-osteoblastic 2T9 cells, inhibits proliferation and stimulates differentiation of osteoblast-like MG63 cells, and increases proliferation and differentiation of normal human osteoblast NHOst cells. J Periodontol 2000;71:1287-1296.
5. Van der Pauw MT, Van den Bos T, Everts V, Beertsen W. Enamel matrix-derived protein stimulates attachment of periodontal ligament fibroblasts and enhances alkaline phosphatase activity and transforming growth factor beta1 release of periodontal ligament and gingival fibroblasts. J Periodontol 2000;71:31-43.
6. Lyngstadaas SP, Lundberg E, Ekdahl H, Andersson C, Gestrelius S. Autocrine growth factors in human periodontal ligament cells cultured on enamel matrix derivative. J Clin Periodontol 2001;28:181-188.
7. Okubo K, Kobayashi M, Takiguchi T, et al. Participation of endogenous IGF-I and TGF-beta 1 with enamel matrix derivative-stimulated cell growth in human periodontal ligament cells. J Periodontal Res 2003;38:1-9.
8. Kawase T, Okuda K, Yoshie H, Burns DM. Cytostatic action of enamel matrix derivative (EMDOGAIN) on human oral squamous cell carcinoma-derived SCC25 epithelial cells. J Periodontal Res 2000;35:291-300.
9. Sculean A, Auschill TM, Donos N, Brecx M, Arweiler NB. Effect of an enamel matrix protein derivative (Emdogain) on ex vivo dental plaque vitality. J Clin Periodontol 2001;28:1074-1078.
10. Arweiler NB, Auschill TM, Donos N, Sculean A. Antibacterial effect of an enamel matrix protein derivative on in vivo dental biofilm vitality. Clin Oral Investig 2002;6:205-209.
11. Mengel R, Soffner M, Flores-de-Jacoby L. Bioabsorbable membrane and bioactive glass in the treatment of intrabony defects in patients with generalized aggressive periodontitis: Results of a 12-month clinical and radiological study. J Periodontol 2003;74:899-908.
12. Greenspan DC. Bioactive glass: Mechanisms of bone bonding. Swed Dent J 1999;91:31-35.
13. Hench LL. Bioactive ceramics. Ann N Y Acad Sci 1988;523:54-71.
14. Vrouwenvelder WCA, Groot CG, de Groot K. Behavior of fetal rat osteoblasts cultured in vitro on bioactive glass and nonreactive glasses. Biomaterials 1992;13:382-392.
15. Sautier JM, Kokubu T, Ohtsuki T, et al. Bioactive glass-ceramic containing crystalline apatite and wollastonite initiates biomineralization in bone cell cultures. Calcif Tissue Int 1994;55:458-466.
16. Scarano A, Degidi M, Iezzi G, et al. Maxillary sinus augmentation with different biomaterials: A comparative histologic and histomorphometric study in man. Implant Dent 2006;15:197-207.
17. Dybvik T, Leknes KN, Bøe OE, Skavland RJ, Albandar JM. Bioactive ceramic filler in the treatment of severe osseous defects: 12-month results. J Periodontol 2007;78:403-410.
18. Zamet JS, Darbar UR, Griffiths GS, et al. Particulate bioglass as a grafting material in the treatment of periodontal intrabony defects. J Clin Periodontol 1997;24:410-418.
19. Froum SJ, Weinberg MA, Tarnow D. Comparison of bioactive glass synthetic bone graft particles and open debridement in the treatment of human periodontal defects. A clinical study. J Periodontol 1998;69:698-709.
20. Lovelace TB, Mellonig JT, Meffert RM, Jones AA, Nummikoski PV, Cochran DL. Clinical evaluation of bioactive glass in the treatment of periodontal osseous defects in humans. J Periodontol 1998;69:1027-1035.
21. Cortellini P, Tonetti MS. Clinical performance of a regenerative strategy for intrabony defects: Scientific evidence and clinical experience. J Periodontol 2005;76:341-350.
22. Rösing CK, Aass AM, Mavropoulos A, Gjermo P. Clinical and radiographic effects of enamel matrix derivative in the treatment of intrabony periodontal defects: A 12-month longitudinal placebo-controlled clinical trial in adult periodontitis patients. J Periodontol 2005;76:129-133.
23. Tonetti MS, Prato GP, Cortellini P. Factors affecting the healing response of intrabony defects following guided tissue regeneration and access flap surgery. J Clin Periodontol 1996;23:548-556.
24. Cortellini P, Tonetti MS. Focus on intrabony defects: Guided tissue regeneration. Periodontol 2000 2000;22:104-132.
25. Kornman KS, Robertson PB. Fundamental principles affecting the outcomes of therapy for osseous lesions. Periodontol 2000 2000;22:22-43.
26. Goldman HM, Cohen DW. The intrabony pocket: Classification and treatment. J Periodontol 1958;29:272-291.
27. O'Leary TJ, Drake RB, Naylor JE. The plaque control record. J Periodontol 1972;43:38.
28. Blomlöf JP, Blomlöf LB, Lindskog S. Smear removal and collagen exposure after non-surgical root planing followed by etching with an EDTA gel preparation. J Periodontol 1996;67:841-845.
29. O'Neal RB, Alleyn CD. Suture materials and techniques. Curr Opin Periodontol 1997;4:89-95.
30. Gibbs CH, Hirschfeld JW, Lee JG, et al. Description and clinical evaluation of a new computerized periodontal probe - The Florida Probe. J Clin Periodontol 1988;15:137-144.
31. Nyman S, Lindhe J. Examination of patients with periodontal disease. In: Lindhe J, Karring T, Lang NP, eds. Clinical Periodontology and Implant Dentistry, 4th ed. Oxford, U.K.: Blackwell Publishing; 2003:403-413.
32. Sculean A, Pietruska M, Arweiler NB, Auschill TM, Nemcovsky C. Four-year results of a prospective-controlled clinical study evaluating healing of intrabony defects following treatment with an enamel matrix protein derivative alone or combined with a bioactive glass. J Clin Periodontol 2007;34:507-513.
33. Heijl L, Heden G, Svärdström G, Östgren A. Enamel matrix derivative (EMDOGAIN) in the treatment of intrabony periodontal defects. J Clin Periodontol 1997;24:705-714.
34. Tonetti MS, Lang NP, Cortellini P, et al. Enamel matrix proteins in the regenerative therapy of deep intrabony defects. A multicentre randomized controlled clinical trial. J Clin Periodontol 2002;29:317-325.
35. Ozcelik O, Cenk Haytac M, Seydaoglu G. Enamel matrix derivative and low-level laser therapy in the treatment of intra-bony defects: A randomized placebo-controlled clinical trial. J Clin Periodontol 2008;35:147-156.
36. Du C, Schneider GB, Zaharias R, et al. Apatite/ amelogenin coating on titanium promotes osteogenic gene expression. J Dent Res 2005;84:1070-1074.
37. Hoang AM, Klebe RJ, Steffensen B, Ryu OH, Simmer JP, Cochran DL. Amelogenin is a cell adhesion protein. J Dent Res 2002;81:497-500.
38. Jepsen S, Schiltz P, Strong DD, Scharla SH, Snead ML, Finkelman RD. Transforming growth factor-beta 1 mRNA in neonatal ovine molars visualized by in situ hybridization: Potential role for the stratum intermedium. Arch Oral Biol 1992;37:645-653.
39. D'Souza RN, Happonen RP, Ritter NM, Butler WT. Temporal and spatial patterns of transforming growth factor-beta 1 expression in developing rat molars. Arch Oral Biol 1990;35:957-965.
40. Wada Y, Yamamoto H, Nanbu S, Mizuno M, Tamura M. The suppressive effect of enamel matrix derivative on osteocalcin gene expression of osteoblasts is neutralized by an antibody against TGF-beta. J Periodontol 2008;79:341-347.
41. Hench LL, Paschall HA. Histochemical responses at a biomaterial's interface. J Biomed Mater Res 1974;8:49-64.
42. Hench LL, Wilson J. Surface-active biomaterials. Science 1984;226:630-636.
43. Nasr HF, Aichelmann-Reidy ME, Yukna RA. Bone and bone substitutes. Periodontol 2000 1999;19:74-86.
44. Reddy MS, Jeffcoat MK. Methods of assessing periodontal regeneration. Periodontol 2000 1999;19:87-103.
45. Tu YK, Tugnait A, Clerehugh V. Is there a temporal trend in the reported treatment efficacy of periodontal regeneration? A meta-analysis of randomized-controlled trials. J Clin Periodontol 2008;35:139-146.