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Volumn 29, Issue 5, 2009, Pages 1277-1284

Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growth

Author keywords

Cytoskeleton; Motor neuron; Myelination; Neurofilaments; Phosphorylation; Radial growth

Indexed keywords

ALANINE; LYSINE; MYELIN; NEUROFILAMENT PROTEIN; PROLINE; SERINE; TUBULIN;

EID: 59649087460     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3765-08.2009     Document Type: Article
Times cited : (43)

References (40)
  • 1
    • 0000756967 scopus 로고
    • A comparison of the characteristics of axons through their individual electrical responses
    • Blair EA, Erlanger J (1933) A comparison of the characteristics of axons through their individual electrical responses. Am J Physiol 106:524-564.
    • (1933) Am J Physiol , vol.106 , pp. 524-564
    • Blair, E.A.1    Erlanger, J.2
  • 2
    • 0025281205 scopus 로고
    • Coexistence of nerve conduction deficit with increased Na(+)-K(+)-ATPase activity in galactose-fed mice. Implications for polyol pathway and diabetic neuropathy
    • Calcutt NA, Tomlinson DR, Biswas S (1990) Coexistence of nerve conduction deficit with increased Na(+)-K(+)-ATPase activity in galactose-fed mice. Implications for polyol pathway and diabetic neuropathy. Diabetes 39:663- 666.
    • (1990) Diabetes , vol.39 , pp. 663-666
    • Calcutt, N.A.1    Tomlinson, D.R.2    Biswas, S.3
  • 3
    • 0033677861 scopus 로고    scopus 로고
    • The C-terminal tail domain of neurofilament protein-H (NF-H) forms the crossbridges and regulates neurofilament bundle formation
    • Chen J, Nakata T, Zhang Z, Hirokawa N (2000) The C-terminal tail domain of neurofilament protein-H (NF-H) forms the crossbridges and regulates neurofilament bundle formation. J Cell Sci 113:3861-3869.
    • (2000) J Cell Sci , vol.113 , pp. 3861-3869
    • Chen, J.1    Nakata, T.2    Zhang, Z.3    Hirokawa, N.4
  • 5
    • 0026580004 scopus 로고
    • Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells
    • de Waegh SM, Lee VM, Brady ST (1992) Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells. Cell 68:451-463.
    • (1992) Cell , vol.68 , pp. 451-463
    • de Waegh, S.M.1    Lee, V.M.2    Brady, S.T.3
  • 6
    • 84981839182 scopus 로고
    • A relationship between axone diameter and myelination determined by measurement of myelinated spinal root fibers
    • Duncan D (1934) A relationship between axone diameter and myelination determined by measurement of myelinated spinal root fibers. J Comp Neurol 60:437-471.
    • (1934) J Comp Neurol , vol.60 , pp. 437-471
    • Duncan, D.1
  • 7
    • 0004929652 scopus 로고
    • The action potential in fibers of slow conduction in spinal roots and somatic nerves
    • Erlanger J, Gasser HS (1930) The action potential in fibers of slow conduction in spinal roots and somatic nerves. Am J Physiol 92:43-82.
    • (1930) Am J Physiol , vol.92 , pp. 43-82
    • Erlanger, J.1    Gasser, H.S.2
  • 9
    • 0023158848 scopus 로고
    • Posttranslational modification of neurofilament polypeptides in rabbit retina
    • Glicksman MA, Soppet D, Willard MB (1987) Posttranslational modification of neurofilament polypeptides in rabbit retina. J Neurobiol 18:167-196.
    • (1987) J Neurobiol , vol.18 , pp. 167-196
    • Glicksman, M.A.1    Soppet, D.2    Willard, M.B.3
  • 10
    • 0032722127 scopus 로고    scopus 로고
    • Abnormal expression of neurofilament proteins in dysmyelinating axons located in the central nervous system of jimpy mutant mice
    • Gotow T, Leterrier JF, Ohsawa Y, Watanabe T, Isahara K, Shibata R, Ikenaka K, Uchiyama Y (1999) Abnormal expression of neurofilament proteins in dysmyelinating axons located in the central nervous system of jimpy mutant mice. Eur J Neurosci 11:3893-3903.
    • (1999) Eur J Neurosci , vol.11 , pp. 3893-3903
    • Gotow, T.1    Leterrier, J.F.2    Ohsawa, Y.3    Watanabe, T.4    Isahara, K.5    Shibata, R.6    Ikenaka, K.7    Uchiyama, Y.8
  • 11
    • 0023689454 scopus 로고
    • Structure of the peripheral domains of neurofilaments revealed by low angle rotary shadowing
    • Hisanaga S, Hirokawa N (1988) Structure of the peripheral domains of neurofilaments revealed by low angle rotary shadowing. J Mol Biol 202:297-305.
    • (1988) J Mol Biol , vol.202 , pp. 297-305
    • Hisanaga, S.1    Hirokawa, N.2
  • 14
    • 0032817551 scopus 로고    scopus 로고
    • Disruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunits
    • Jacomy H, Zhu Q, Couillard-Després S, Beaulieu JM, Julien JP (1999) Disruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunits. J Neurochem 73:972-984.
    • (1999) J Neurochem , vol.73 , pp. 972-984
    • Jacomy, H.1    Zhu, Q.2    Couillard-Després, S.3    Beaulieu, J.M.4    Julien, J.P.5
  • 16
    • 0020469579 scopus 로고
    • Multiple phosphorylation sites in mammalian neurofilament polypeptides
    • Julien JP, Mushynski WE (1982) Multiple phosphorylation sites in mammalian neurofilament polypeptides. J Biol Chem 257:10467-10470.
    • (1982) J Biol Chem , vol.257 , pp. 10467-10470
    • Julien, J.P.1    Mushynski, W.E.2
  • 18
    • 0034576145 scopus 로고    scopus 로고
    • Electrophysiological properties of axons in mice lacking neurofilament subunit genes: Disparity between conduction velocity and axon diameter in absence of NF-H
    • Kriz J, Zhu Q, Julien JP, Padjen AL (2000) Electrophysiological properties of axons in mice lacking neurofilament subunit genes: disparity between conduction velocity and axon diameter in absence of NF-H. Brain Res 885:32-44.
    • (2000) Brain Res , vol.885 , pp. 32-44
    • Kriz, J.1    Zhu, Q.2    Julien, J.P.3    Padjen, A.L.4
  • 19
    • 0025000571 scopus 로고
    • The expression and posttranslational modification of a neuron-specific beta-tubulin isotype during chick embryogenesis
    • Lee MK, Tuttle JB, Rebhun LI, Cleveland DW, Frankfurter A (1990) The expression and posttranslational modification of a neuron-specific beta-tubulin isotype during chick embryogenesis. Cell Motil Cytoskeleton 17:118-132.
    • (1990) Cell Motil Cytoskeleton , vol.17 , pp. 118-132
    • Lee, M.K.1    Tuttle, J.B.2    Rebhun, L.I.3    Cleveland, D.W.4    Frankfurter, A.5
  • 20
    • 0027293898 scopus 로고
    • Neurofilaments are obligate heteropolymers in vivo
    • Lee MK, Xu Z, Wong PC, Cleveland DW (1993) Neurofilaments are obligate heteropolymers in vivo. J Cell Biol 122:1337-1350.
    • (1993) J Cell Biol , vol.122 , pp. 1337-1350
    • Lee, M.K.1    Xu, Z.2    Wong, P.C.3    Cleveland, D.W.4
  • 21
    • 0023378106 scopus 로고
    • Structure and evolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein
    • Levy E, Liem RK, D'Eustachio P, Cowan NJ (1987) Structure and evolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein. Eur J Biochem 166:71-77.
    • (1987) Eur J Biochem , vol.166 , pp. 71-77
    • Levy, E.1    Liem, R.K.2    D'Eustachio, P.3    Cowan, N.J.4
  • 22
    • 0024242689 scopus 로고
    • Multiple phosphorylated variants of the high molecular mass subunit of neurofilaments in axons of retinal cell neurons: Characterization and evidence for their differential association with stationary and moving neurofilaments
    • Lewis SE, Nixon RA (1988) Multiple phosphorylated variants of the high molecular mass subunit of neurofilaments in axons of retinal cell neurons: characterization and evidence for their differential association with stationary and moving neurofilaments. J Cell Biol 107:2689-2701.
    • (1988) J Cell Biol , vol.107 , pp. 2689-2701
    • Lewis, S.E.1    Nixon, R.A.2
  • 23
    • 0023425413 scopus 로고
    • In vivo microtubules are copolymers of available beta-tubulin isotypes: Localization of each of six vertebrate beta-tubulin isotypes using polyclonal antibodies elicited by synthetic peptide antigens
    • Lopata MA, Cleveland DW (1987) In vivo microtubules are copolymers of available beta-tubulin isotypes: localization of each of six vertebrate beta-tubulin isotypes using polyclonal antibodies elicited by synthetic peptide antigens. J Cell Biol 105:1707-1720.
    • (1987) J Cell Biol , vol.105 , pp. 1707-1720
    • Lopata, M.A.1    Cleveland, D.W.2
  • 24
    • 0023357815 scopus 로고
    • The human mid-size neurofilament subunit: A repeated protein sequence and the relationship of its gene to the intermediate filament gene family
    • Myers MW, Lazzarini RA, Lee VM, Schlaepfer WW, Nelson DL (1987) The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family. EMBO J 6:1617-1626.
    • (1987) EMBO J , vol.6 , pp. 1617-1626
    • Myers, M.W.1    Lazzarini, R.A.2    Lee, V.M.3    Schlaepfer, W.W.4    Nelson, D.L.5
  • 25
    • 0028900588 scopus 로고
    • Two distinct functions of the carboxyl-terminal tail domain of NF-M upon neurofilament assembly: Cross-bridge formation and longitudinal elongation of filaments
    • Nakagawa T, Chen J, Zhang Z, Kanai Y, Hirokawa N (1995) Two distinct functions of the carboxyl-terminal tail domain of NF-M upon neurofilament assembly: cross-bridge formation and longitudinal elongation of filaments. J Cell Biol 129:411-429.
    • (1995) J Cell Biol , vol.129 , pp. 411-429
    • Nakagawa, T.1    Chen, J.2    Zhang, Z.3    Kanai, Y.4    Hirokawa, N.5
  • 26
    • 0027931132 scopus 로고
    • Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: Influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber
    • Nixon RA, Paskevich PA, Sihag RK, Thayer CY (1994) Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber. J Cell Biol 126:1031-1046.
    • (1994) J Cell Biol , vol.126 , pp. 1031-1046
    • Nixon, R.A.1    Paskevich, P.A.2    Sihag, R.K.3    Thayer, C.Y.4
  • 27
    • 0027530064 scopus 로고
    • Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene
    • Ohara O, Gahara Y, Miyake T, Teraoka H, Kitamura T (1993) Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene. J Cell Biol 121:387-395.
    • (1993) J Cell Biol , vol.121 , pp. 387-395
    • Ohara, O.1    Gahara, Y.2    Miyake, T.3    Teraoka, H.4    Kitamura, T.5
  • 28
    • 0037135978 scopus 로고    scopus 로고
    • Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport
    • Rao MV, Garcia ML, Miyazaki Y, Gotow T, Yuan A, Mattina S, Ward CM, Calcutt NA, Uchiyama Y, Nixon RA, Cleveland DW (2002) Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport. J Cell Biol 158:681-693.
    • (2002) J Cell Biol , vol.158 , pp. 681-693
    • Rao, M.V.1    Garcia, M.L.2    Miyazaki, Y.3    Gotow, T.4    Yuan, A.5    Mattina, S.6    Ward, C.M.7    Calcutt, N.A.8    Uchiyama, Y.9    Nixon, R.A.10    Cleveland, D.W.11
  • 29
    • 0346849719 scopus 로고    scopus 로고
    • The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate
    • Rao MV, Campbell J, Yuan A, Kumar A, Gotow T, Uchiyama Y, Nixon RA (2003) The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate. J Cell Biol 163:1021-1031.
    • (2003) J Cell Biol , vol.163 , pp. 1021-1031
    • Rao, M.V.1    Campbell, J.2    Yuan, A.3    Kumar, A.4    Gotow, T.5    Uchiyama, Y.6    Nixon, R.A.7
  • 30
    • 84944495904 scopus 로고
    • A theory of the effects of fibre size in medullated nerve
    • Rushton WA (1951) A theory of the effects of fibre size in medullated nerve. J Physiol 115:101-122.
    • (1951) J Physiol , vol.115 , pp. 101-122
    • Rushton, W.A.1
  • 31
    • 0027238901 scopus 로고
    • Reduced diameter and conduction velocity of myelinated fibers in the sciatic nerve of a neurofilament-deficient mutant quail
    • Sakaguchi T, Okada M, Kitamura T, Kawasaki K (1993) Reduced diameter and conduction velocity of myelinated fibers in the sciatic nerve of a neurofilament-deficient mutant quail. Neurosci Lett 153:65-68.
    • (1993) Neurosci Lett , vol.153 , pp. 65-68
    • Sakaguchi, T.1    Okada, M.2    Kitamura, T.3    Kawasaki, K.4
  • 32
    • 0034722377 scopus 로고    scopus 로고
    • Local control of neurofilament accumulation during radial growth of myelinating axons in vivo. Selective role of site-specific phosphorylation
    • Sánchez I, Hassinger L, Sihag RK, Cleveland DW, Mohan P, Nixon RA (2000) Local control of neurofilament accumulation during radial growth of myelinating axons in vivo. Selective role of site-specific phosphorylation. J Cell Biol 151:1013-1024.
    • (2000) J Cell Biol , vol.151 , pp. 1013-1024
    • Sánchez, I.1    Hassinger, L.2    Sihag, R.K.3    Cleveland, D.W.4    Mohan, P.5    Nixon, R.A.6
  • 33
    • 0034708818 scopus 로고    scopus 로고
    • Response of Schwann cells to action potentials in development
    • Stevens B, Fields RD (2000) Response of Schwann cells to action potentials in development. Science 287:2267-2271.
    • (2000) Science , vol.287 , pp. 2267-2271
    • Stevens, B.1    Fields, R.D.2
  • 34
    • 0029805514 scopus 로고    scopus 로고
    • Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton
    • Svitkina TM, Verkhovsky AB, Borisy GG (1996) Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton. J Cell Biol 135:991-1007.
    • (1996) J Cell Biol , vol.135 , pp. 991-1007
    • Svitkina, T.M.1    Verkhovsky, A.B.2    Borisy, G.G.3
  • 35
    • 0029052277 scopus 로고
    • Overexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunits
    • Tu PH, Elder G, Lazzarini RA, Nelson D, Trojanowski JQ, Lee VM (1995) Overexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunits. J Cell Biol 129:1629-1640.
    • (1995) J Cell Biol , vol.129 , pp. 1629-1640
    • Tu, P.H.1    Elder, G.2    Lazzarini, R.A.3    Nelson, D.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 36
    • 0027410516 scopus 로고
    • Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
    • Xu Z, Cork LC, Griffin JW, Cleveland DW (1993) Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell 73:23-33.
    • (1993) Cell , vol.73 , pp. 23-33
    • Xu, Z.1    Cork, L.C.2    Griffin, J.W.3    Cleveland, D.W.4
  • 37
    • 0026668808 scopus 로고
    • Identification of six phosphorylation sites in the COOH-terminal tail region of the rat neurofilament protein M
    • Xu ZS, Liu WS, Willard MB (1992) Identification of six phosphorylation sites in the COOH-terminal tail region of the rat neurofilament protein M. J Biol Chem 267:4467-4471.
    • (1992) J Biol Chem , vol.267 , pp. 4467-4471
    • Xu, Z.S.1    Liu, W.S.2    Willard, M.B.3
  • 38
    • 0032521342 scopus 로고    scopus 로고
    • Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons
    • Yin X, Crawford TO, Griffin JW, Tu P, Lee VM, Li C, Roder J, Trapp BD (1998) Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons. J Neurosci 18:1953-1962.
    • (1998) J Neurosci , vol.18 , pp. 1953-1962
    • Yin, X.1    Crawford, T.O.2    Griffin, J.W.3    Tu, P.4    Lee, V.M.5    Li, C.6    Roder, J.7    Trapp, B.D.8
  • 39
    • 29244471690 scopus 로고    scopus 로고
    • Deleting the phosphorylated tail domain of the neurofilament heavy subunit does not alter neurofilament transport rate in vivo
    • Yuan A, Nixon RA, Rao MV (2006) Deleting the phosphorylated tail domain of the neurofilament heavy subunit does not alter neurofilament transport rate in vivo. Neurosci Lett 393:264-268.
    • (2006) Neurosci Lett , vol.393 , pp. 264-268
    • Yuan, A.1    Nixon, R.A.2    Rao, M.V.3
  • 40
    • 0031263931 scopus 로고    scopus 로고
    • Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments
    • Zhu Q, Couillard-Després S, Julien JP (1997) Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments. Experimental Neurology 148:299 -316.
    • (1997) Experimental Neurology , vol.148 , pp. 299-316
    • Zhu, Q.1    Couillard-Després, S.2    Julien, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.