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Volumn 115, Issue 2, 2009, Pages 373-380

Chemoimmunotherapy may overcome the adverse prognostic significance of 11q deletion in previously untreated patients with chronic lymphocytic leukemia

Author keywords

11q deletion; ATM; CLL; FCR; FISH

Indexed keywords

ALEMTUZUMAB; ATM PROTEIN; CYCLOPHOSPHAMIDE; FLUDARABINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MITOXANTRONE; PREDNISONE; PROTEIN P53; RITUXIMAB; VINCRISTINE;

EID: 59449110380     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.23993     Document Type: Article
Times cited : (100)

References (33)
  • 1
    • 0024205754 scopus 로고
    • Localization of an ataxia-telangiectasia gene to chromosome 11q22-23
    • Gatti RA, Berkel I, Boder E, et al. Localization of an ataxia-telangiectasia gene to chromosome 11q22-23. Nature. 1988;336:577-580.
    • (1988) Nature , vol.336 , pp. 577-580
    • Gatti, R.A.1    Berkel, I.2    Boder, E.3
  • 2
    • 0016786321 scopus 로고
    • Ataxia telan- giectasia: A human mutation with abnormal radiation sensitivity
    • Taylor AM, Harnden DG, Arlett CF, et al. Ataxia telan- giectasia: a human mutation with abnormal radiation sensitivity. Nature. 1975;258:427-429.
    • (1975) Nature , vol.258 , pp. 427-429
    • Taylor, A.M.1    Harnden, D.G.2    Arlett, C.F.3
  • 3
    • 0029057336 scopus 로고
    • A single ataxia telangiectasia gene with a product similar to PI-3 kinase
    • Savitsky K, Bar-Shira A, Gilad S, et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science. 1995;268:1749-1753.
    • (1995) Science , vol.268 , pp. 1749-1753
    • Savitsky, K.1    Bar-Shira, A.2    Gilad, S.3
  • 4
    • 0032944319 scopus 로고    scopus 로고
    • ATM mutations in B- cell chronic lymphocytic leukemia
    • Bullrich F, Rasio D, Kitada S, et al. ATM mutations in B- cell chronic lymphocytic leukemia. Cancer Res. 1999;59:24-27.
    • (1999) Cancer Res , vol.59 , pp. 24-27
    • Bullrich, F.1    Rasio, D.2    Kitada, S.3
  • 5
    • 0033566329 scopus 로고    scopus 로고
    • Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia
    • Schaffner C, Stilgenbauer S, Rappold GA, Dohner H, Lichter P. Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia. Blood. 1999;94:748-753.
    • (1999) Blood , vol.94 , pp. 748-753
    • Schaffner, C.1    Stilgenbauer, S.2    Rappold, G.A.3    Dohner, H.4    Lichter, P.5
  • 6
    • 0033513587 scopus 로고    scopus 로고
    • Inactivation of ataxia telangiectasia mutated gene in B- cell chronic lympho- cytic leukaemia
    • Stankovic T, Weber P, Stewart G, et al. Inactivation of ataxia telangiectasia mutated gene in B- cell chronic lympho- cytic leukaemia. Lancet. 1999;353:26-29.
    • (1999) Lancet , vol.353 , pp. 26-29
    • Stankovic, T.1    Weber, P.2    Stewart, G.3
  • 7
    • 0036096157 scopus 로고    scopus 로고
    • Ataxia telangiecta- sia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage
    • Stankovic T, Stewart GS, Fegan C, et al. Ataxia telangiecta- sia mutated-deficient B-cell chronic lymphocytic leukemia occurs in pregerminal center cells and results in defective damage response and unrepaired chromosome damage. Blood. 2002;99:300-309.
    • (2002) Blood , vol.99 , pp. 300-309
    • Stankovic, T.1    Stewart, G.S.2    Fegan, C.3
  • 8
    • 34250358742 scopus 로고    scopus 로고
    • Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinoma
    • Parikh RA, White JS, Huang X, et al. Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinoma. Genes Chromosomes Cancer. 2007;46:761-775.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 761-775
    • Parikh, R.A.1    White, J.S.2    Huang, X.3
  • 9
    • 15844426692 scopus 로고    scopus 로고
    • Atm-deficient mice: A paradigm of ataxia telangiectasia
    • Barlow C, Hirotsune S, Paylor R, et al. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell. 1996;86:159-171.
    • (1996) Cell , vol.86 , pp. 159-171
    • Barlow, C.1    Hirotsune, S.2    Paylor, R.3
  • 10
    • 0029844048 scopus 로고    scopus 로고
    • Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma
    • Xu Y, Ashley T, Brainerd EE, Bronson RT, Meyn MS, Baltimore D. Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Genes Dev. 1996;10: 2411-2422.
    • (1996) Genes Dev , vol.10 , pp. 2411-2422
    • Xu, Y.1    Ashley, T.2    Brainerd, E.E.3    Bronson, R.T.4    Meyn, M.S.5    Baltimore, D.6
  • 11
    • 1842328565 scopus 로고    scopus 로고
    • 11q deletions identify a new subset of B- cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis
    • Dohner H, Stilgenbauer S, James MR, et al. 11q deletions identify a new subset of B- cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis. Blood. 1997;89:2516-2522.
    • (1997) Blood , vol.89 , pp. 2516-2522
    • Dohner, H.1    Stilgenbauer, S.2    James, M.R.3
  • 12
    • 0029614780 scopus 로고
    • Karyotypic evolution in CLL: Identification of a new sub-group of patients with deletions of 11q and advanced or progressive disease
    • Fegan C, Robinson H, Thompson P, Whittaker JA, White D. Karyotypic evolution in CLL: identification of a new sub-group of patients with deletions of 11q and advanced or progressive disease. Leukemia. 1995;9:2003-2008.
    • (1995) Leukemia , vol.9 , pp. 2003-2008
    • Fegan, C.1    Robinson, H.2    Thompson, P.3    Whittaker, J.A.4    White, D.5
  • 13
    • 0030706137 scopus 로고    scopus 로고
    • Deletions at 11q identify a subset of patients with typical CLL who show consistent disease progression and reduced survival
    • Neilson JR, Auer R, White D, et al. Deletions at 11q identify a subset of patients with typical CLL who show consistent disease progression and reduced survival. Leukemia. 1997;11:1929-1932.
    • (1997) Leukemia , vol.11 , pp. 1929-1932
    • Neilson, J.R.1    Auer, R.2    White, D.3
  • 14
    • 0023110886 scopus 로고
    • Clonal chromosome abnormalities in chronic lymphocytic leukemia patients revealed by TPA stimulation of whole blood cultures
    • Ross FM, Stockdill G. Clonal chromosome abnormalities in chronic lymphocytic leukemia patients revealed by TPA stimulation of whole blood cultures. Cancer Genet Cytogenet. 1987;25:109-121.
    • (1987) Cancer Genet Cytogenet , vol.25 , pp. 109-121
    • Ross, F.M.1    Stockdill, G.2
  • 15
    • 0034727833 scopus 로고    scopus 로고
    • Genomic aberrations and survival in chronic lymphocytic leukemia
    • Dohner H, Stilgenbauer S, Benner A, et al. Genomic aberrations and survival in chronic lymphocytic leukemia. NEngl J Med. 2000;343:1910-1916.
    • (2000) NEngl J Med , vol.343 , pp. 1910-1916
    • Dohner, H.1    Stilgenbauer, S.2    Benner, A.3
  • 16
    • 0003154174 scopus 로고    scopus 로고
    • He- matology. Basic Principles and Practice. 3rd ed, Churchill Livingstone;
    • Rai K, Patel DV. Chronic lymphocytic leukemia. In: He- matology. Basic Principles and Practice. 3rd ed. Philadelphia, PA: Churchill Livingstone; 2000:1350-1363.
    • (2000) Chronic lymphocytic leukemia , pp. 1350-1363
    • Rai, K.1    Patel, D.V.2
  • 17
    • 0029981025 scopus 로고    scopus 로고
    • National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
    • Cheson BD, Bennett JM, Grever M, et al. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood. 1996;87:4990-4997.
    • (1996) Blood , vol.87 , pp. 4990-4997
    • Cheson, B.D.1    Bennett, J.M.2    Grever, M.3
  • 18
    • 0035282055 scopus 로고    scopus 로고
    • Results of the fludarabine and cyclophosphamide combination regimen in chronic lymphocytic leukemia
    • O'Brien SM, Kantarjian HM, Cortes J, et al. Results of the fludarabine and cyclophosphamide combination regimen in chronic lymphocytic leukemia. J Clin Oncol. 2001;19:1414- 1420.
    • (2001) J Clin Oncol , vol.19 , pp. 1414-1420
    • O'Brien, S.M.1    Kantarjian, H.M.2    Cortes, J.3
  • 19
    • 23044510136 scopus 로고    scopus 로고
    • Early results of a chemoimmunotherapy regimen of fludarabine, cyclophos- phamide, and rituximab as initial therapy for chronic lym- phocytic leukemia
    • Keating MJ, O'Brien S, Albitar M, et al. Early results of a chemoimmunotherapy regimen of fludarabine, cyclophos- phamide, and rituximab as initial therapy for chronic lym- phocytic leukemia. J Clin Oncol. 2005;23:4079-4088.
    • (2005) J Clin Oncol , vol.23 , pp. 4079-4088
    • Keating, M.J.1    O'Brien, S.2    Albitar, M.3
  • 20
    • 59449102082 scopus 로고    scopus 로고
    • McLaughlin P, Liu N, Poindexter N, et al. Rituximab plus GM- CSF for indolent lymphoma [abstract]. Proceedings of the 9th International Conference on Malignant Lympho- mas, Lugano, Switzerland. Ann Oncol. 2005;16(suppl 5):104. Abstract 68.
    • McLaughlin P, Liu N, Poindexter N, et al. Rituximab plus GM- CSF for indolent lymphoma [abstract]. Proceedings of the 9th International Conference on Malignant Lympho- mas, Lugano, Switzerland. Ann Oncol. 2005;16(suppl 5):104. Abstract 68.
  • 21
    • 34447530283 scopus 로고    scopus 로고
    • Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): A randomised controlled trial
    • Catovsky D, Richards S, Matutes E, et al. Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial. Lancet. 2007;370:230-239.
    • (2007) Lancet , vol.370 , pp. 230-239
    • Catovsky, D.1    Richards, S.2    Matutes, E.3
  • 22
    • 0025112785 scopus 로고
    • Prognostic subgroups in B- cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities
    • Juliusson G, Oscier DG, Fitchett M, et al. Prognostic subgroups in B- cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities. N Engl J Med. 1990; 323:720-724.
    • (1990) N Engl J Med , vol.323 , pp. 720-724
    • Juliusson, G.1    Oscier, D.G.2    Fitchett, M.3
  • 23
    • 0029417029 scopus 로고
    • Cytogenetic analysis of B cell chronic lymphoid leukemias classified according to morphologic and immunophenotypic (FAB) criteria
    • Hernandez J M, Mecucci C, Criel A, et al. Cytogenetic analysis of B cell chronic lymphoid leukemias classified according to morphologic and immunophenotypic (FAB) criteria. Leukemia. 1995;9:2140-2146.
    • (1995) Leukemia , vol.9 , pp. 2140-2146
    • Hernandez, J.M.1    Mecucci, C.2    Criel, A.3
  • 24
    • 36348953152 scopus 로고    scopus 로고
    • Comprehensive genetic characterization of CLL: A study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping
    • Haferlach C, Dicker F, Schnittger S, Kern W, Haferlach T. Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping. Leukemia. 2007;21:2442-2451.
    • (2007) Leukemia , vol.21 , pp. 2442-2451
    • Haferlach, C.1    Dicker, F.2    Schnittger, S.3    Kern, W.4    Haferlach, T.5
  • 25
    • 0032532095 scopus 로고    scopus 로고
    • Deficiency of the ATM protein expression defines an aggressive subgroup of B- cell chronic lymphocytic leukemia
    • Starostik P, Manshouri T, O'Brien S, et al. Deficiency of the ATM protein expression defines an aggressive subgroup of B- cell chronic lymphocytic leukemia. Cancer Res. 1998; 58:4552-4557.
    • (1998) Cancer Res , vol.58 , pp. 4552-4557
    • Starostik, P.1    Manshouri, T.2    O'Brien, S.3
  • 26
    • 0036272536 scopus 로고    scopus 로고
    • Expression profile of 11 proteins and their prognostic significance in patients with chronic lymphocytic leukemia (CLL)
    • Faderl S, Keating M J, Do KA, et al. Expression profile of 11 proteins and their prognostic significance in patients with chronic lymphocytic leukemia (CLL). Leukemia. 2002; 16:1045-1052.
    • (2002) Leukemia , vol.16 , pp. 1045-1052
    • Faderl, S.1    Keating, M.J.2    Do, K.A.3
  • 27
    • 35748932373 scopus 로고    scopus 로고
    • Assessment of chronic lymphocytic leukemia and small lymphocytic lym- phoma by absolute lymphocyte counts in 2,126 patients: 20 years of experience at the University of Texas M.D. Anderson Cancer Center
    • Tsimberidou AM, Wen S, O'Brien S, et al. Assessment of chronic lymphocytic leukemia and small lymphocytic lym- phoma by absolute lymphocyte counts in 2,126 patients: 20 years of experience at the University of Texas M.D. Anderson Cancer Center. J Clin Oncol. 2007;25:4648-4656.
    • (2007) J Clin Oncol , vol.25 , pp. 4648-4656
    • Tsimberidou, A.M.1    Wen, S.2    O'Brien, S.3
  • 28
    • 33644847307 scopus 로고    scopus 로고
    • Select high-risk genetic features predict earlier progression following chemo- immunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: Justification for risk-adapted therapy
    • Byrd JC, Gribben JG, Peterson BL, et al. Select high-risk genetic features predict earlier progression following chemo- immunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy. J Clin Oncol. 2006;24:437-443.
    • (2006) J Clin Oncol , vol.24 , pp. 437-443
    • Byrd, J.C.1    Gribben, J.G.2    Peterson, B.L.3
  • 29
    • 27744549869 scopus 로고    scopus 로고
    • Allogeneic transplant with reduced intensity conditioning regimens may overcome the poor prognosis of B- cell chronic lym- phocytic leukemia with unmutated immunoglobulin variable heavy-chain gene and chromosomal abnormalities (11q- and 17p-)
    • Caballero D, Garcia-Marco JA, Martino R, et al. Allogeneic transplant with reduced intensity conditioning regimens may overcome the poor prognosis of B- cell chronic lym- phocytic leukemia with unmutated immunoglobulin variable heavy-chain gene and chromosomal abnormalities (11q- and 17p-). Clin Cancer Res. 2005;11:7757-7763.
    • (2005) Clin Cancer Res , vol.11 , pp. 7757-7763
    • Caballero, D.1    Garcia-Marco, J.A.2    Martino, R.3
  • 30
    • 27644450586 scopus 로고    scopus 로고
    • Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B- CLL
    • Austen B, Powell JE, Alvi A, et al. Mutations in the ATM gene lead to impaired overall and treatment-free survival that is independent of IGVH mutation status in patients with B- CLL. Blood. 2005;106:3175-3182.
    • (2005) Blood , vol.106 , pp. 3175-3182
    • Austen, B.1    Powell, J.E.2    Alvi, A.3
  • 31
    • 5444276626 scopus 로고    scopus 로고
    • Microarray gene expression profiling of B- cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation status
    • Haslinger C, Schweifer N, Stilgenbauer S, et al. Microarray gene expression profiling of B- cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation status. J Clin Oncol. 2004;22:3937-3949.
    • (2004) J Clin Oncol , vol.22 , pp. 3937-3949
    • Haslinger, C.1    Schweifer, N.2    Stilgenbauer, S.3
  • 32
    • 34848829606 scopus 로고    scopus 로고
    • ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B- cell chronic lymphocytic leukemia
    • Joshi AD, Hegde GV, Dickinson JD, et al. ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B- cell chronic lymphocytic leukemia. Clin Cancer Res. 2007;13:5295-5304.
    • (2007) Clin Cancer Res , vol.13 , pp. 5295-5304
    • Joshi, A.D.1    Hegde, G.V.2    Dickinson, J.D.3
  • 33
    • 36849045647 scopus 로고    scopus 로고
    • Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion
    • Austen B, Skowronska A, Baker C, et al. Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion. J Clin Oncol. 2007;25:5448-5457
    • (2007) J Clin Oncol , vol.25 , pp. 5448-5457
    • Austen, B.1    Skowronska, A.2    Baker, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.