Recurrent intrathecal methotrexate induced neurotoxicity in an adolescent with acute lymphoblastic leukemia: Serial clinical and radiologic findings

Pediatric Blood and Cancer

Volumn 52, Issue 2, 2009, Pages 293-295

  Brugnoletti, Fulvia ^a   Morris, E Brannon ^a,b   Laningham, Fred H ^a,b   Patay, Zoltán ^a,b   Pauley, Jennifer L ^a,c   Pui, Ching Hon ^a,b   Jeha, Sima ^a,b   Inaba, Hiroto ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Diffusion weighted imaging; Intrathecal therapy; Leukemia; Magnetic resonance imaging; Methotrexate; Neurotoxicity

Indexed keywords

AMINOPHYLLINE; ASPARAGINASE MACROGOL; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; FOLINIC ACID; HYDROCORTISONE; METHOTREXATE; PREDNISONE; TIOGUANINE; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ANAMNESIS; ARTICLE; CASE REPORT; CLINICAL FEATURE; DIAGNOSTIC IMAGING; DIFFUSION WEIGHTED IMAGING; DISEASE SEVERITY; DRUG WITHDRAWAL; DYSARTHRIA; HEMIPARESIS; HUMAN; LEUKOENCEPHALOPATHY; MALE; MENTAL INSTABILITY; MULTIPLE CYCLE TREATMENT; NEUROLOGIC EXAMINATION; NEUROTOXICITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PTOSIS; RECURRENT DISEASE; SLURRED SPEECH; DIFFUSION; INTRASPINAL DRUG ADMINISTRATION; PARESIS; SPEECH DISORDER; TOXICITY AND INTOXICATION;

ADOLESCENT; DIFFUSION; HUMANS; INJECTIONS, SPINAL; MAGNETIC RESONANCE IMAGING; MALE; METHOTREXATE; NEUROTOXICITY SYNDROMES; PARESIS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECURRENCE; SPEECH DISORDERS;

EID: 59449108882     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.21764     Document Type: Article

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