-
1
-
-
3342894130
-
Targeting death receptors in cancer with Apo2L/TRAIL
-
Kelley SK, Ashkenazi A. Targeting death receptors in cancer with Apo2L/TRAIL. Curr Opin Pharmacol 2004;4:333-9.
-
(2004)
Curr Opin Pharmacol
, vol.4
, pp. 333-339
-
-
Kelley, S.K.1
Ashkenazi, A.2
-
2
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
Ashkenazi A, Pai RC, Fong S, et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin lnvest1999;104:155-62.
-
J Clin lnvest1999;104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
-
3
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-induc-ing ligand in vivo
-
Walczak H, Miller RE, Ariail K, et al.Tumoricidal activity of tumor necrosis factor-related apoptosis-induc-ing ligand in vivo. Nat Med 1999;5:157-63.
-
(1999)
Nat Med
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
-
4
-
-
33846457870
-
-
Jemal A, Siegel R, Ward E, Murray T, Xu J. Thun M. Cancer Statistics, 2007. CA Cancer J Clin 2007;57:43-66.
-
Jemal A, Siegel R, Ward E, Murray T, Xu J. Thun M. Cancer Statistics, 2007. CA Cancer J Clin 2007;57:43-66.
-
-
-
-
5
-
-
33749578370
-
Gene therapy with TRAIL against renal cell carcinoma
-
Matsubara H, Mizutani Y, Hongo F, et al. Gene therapy with TRAIL against renal cell carcinoma. Mol Cancer Ther 2006;5:2165-71.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2165-2171
-
-
Matsubara, H.1
Mizutani, Y.2
Hongo, F.3
-
6
-
-
33646823935
-
-
Tian JQ, Wang ZP, Rodriguez R, Fu JS, Lu JZ, Ma BL. In vitro enhanced cytotoxicity of tumor-infiltrating lymphocytes transfected with tumor necrosis factor-related apoptosis-inducing ligand and/or interleukin-2 gene in human renal cell carcinoma. Urology 2006;67:1093-8. Epub 2006 Apr 25.
-
Tian JQ, Wang ZP, Rodriguez R, Fu JS, Lu JZ, Ma BL. In vitro enhanced cytotoxicity of tumor-infiltrating lymphocytes transfected with tumor necrosis factor-related apoptosis-inducing ligand and/or interleukin-2 gene in human renal cell carcinoma. Urology 2006;67:1093-8. Epub 2006 Apr 25.
-
-
-
-
7
-
-
33646816024
-
Enhancement of Ad5-TRAIL cytotoxicity against renal cell carcinoma with histone deacetylase inhibitors
-
Van Oosten RL, Earel JK, Jr., Griffith TS. Enhancement of Ad5-TRAIL cytotoxicity against renal cell carcinoma with histone deacetylase inhibitors. Cancer Gene Ther 2006;13:628-32.
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 628-632
-
-
Van Oosten, R.L.1
Earel Jr., J.K.2
Griffith, T.S.3
-
8
-
-
33646403907
-
Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apo-ptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo
-
Zeng Y, Wu XX, Fiscella M, et al. Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apo-ptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo. Int J Oncol 2006;28:421-30.
-
(2006)
Int J Oncol
, vol.28
, pp. 421-430
-
-
Zeng, Y.1
Wu, X.X.2
Fiscella, M.3
-
10
-
-
0020376310
-
Prognostic significance of morphologic parameters in renal cell carcinoma
-
Fuhrman SA, Lasky LC, Limas C. Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol 1982;6:655-63.
-
(1982)
Am J Surg Pathol
, vol.6
, pp. 655-663
-
-
Fuhrman, S.A.1
Lasky, L.C.2
Limas, C.3
-
11
-
-
33646393778
-
Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs
-
Ganten TM, Koschny R, Sykora J, et al. Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs. Clin Cancer Res 2006;12:2640-6.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2640-2646
-
-
Ganten, T.M.1
Koschny, R.2
Sykora, J.3
-
12
-
-
0001458215
-
Effect of more than one inhibitor
-
New York: Academic Press;
-
Webb J. Effect of more than one inhibitor. In: Enzyme and Metabolic Inhibitors. Vol. 1. New York: Academic Press;1963. p. 466-87.
-
(1963)
Enzyme and Metabolic Inhibitors
, vol.1
, pp. 466-487
-
-
Webb, J.1
-
13
-
-
0035137696
-
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
-
Takeda K, Hayakawa Y, Smyth MJ, et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nat Med 2001;7:94-100.
-
(2001)
Nat Med
, vol.7
, pp. 94-100
-
-
Takeda, K.1
Hayakawa, Y.2
Smyth, M.J.3
-
14
-
-
0037226644
-
Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer
-
Seki N, Hayakawa Y, Brooks AD, et al. Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer. Cancer Res 2003;63:207-13.
-
(2003)
Cancer Res
, vol.63
, pp. 207-213
-
-
Seki, N.1
Hayakawa, Y.2
Brooks, A.D.3
-
15
-
-
0035911242
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon 7-dependent natural killer cell protection from tumor metastasis
-
Smyth MJ, Cretney E, Takeda K, et al. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon 7-dependent natural killer cell protection from tumor metastasis. J Exp Med 2001;193:661-70.
-
(2001)
J Exp Med
, vol.193
, pp. 661-670
-
-
Smyth, M.J.1
Cretney, E.2
Takeda, K.3
-
16
-
-
22344432122
-
Evaluating the expression and prognostic value of TRAIL-R1 and TRAIL-R2 in breast cancer
-
McCarthy MM, Sznol M, DiVito KA, Camp RL, Rimm DL, Kluger HM. Evaluating the expression and prognostic value of TRAIL-R1 and TRAIL-R2 in breast cancer. Clin Cancer Res 2005;11:5188-94.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5188-5194
-
-
McCarthy, M.M.1
Sznol, M.2
DiVito, K.A.3
Camp, R.L.4
Rimm, D.L.5
Kluger, H.M.6
-
17
-
-
0042835740
-
Expression of TRAIL and TRAIL death receptors in stage III non-small cell lung cancer tumors
-
Spierings DC, de Vries EG, Timens W, Groen HJ, Boezen HM, de Jong S. Expression of TRAIL and TRAIL death receptors in stage III non-small cell lung cancer tumors. Clin Cancer Res 2003;9:3397-405.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3397-3405
-
-
Spierings, D.C.1
de Vries, E.G.2
Timens, W.3
Groen, H.J.4
Boezen, H.M.5
de Jong, S.6
-
18
-
-
33750958561
-
Prognostic significance of tumor necrosis factor-related apoptosis-inducing ligand and its receptors in adjuv-antly treated stage III colon cancer patients
-
van Geelen CM, Westra JL, deVries EG, et al. Prognostic significance of tumor necrosis factor-related apoptosis-inducing ligand and its receptors in adjuv-antly treated stage III colon cancer patients. J Clin Oncol 2006;24:4998-5004.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4998-5004
-
-
van Geelen, C.M.1
Westra, J.L.2
deVries, E.G.3
-
19
-
-
0036898832
-
Expression of TRAIL and TRAIL receptors in colon carcinoma: TRAIL-R1 is an independent prognostic parameter
-
Strater J, Hinz U, Walczak H, et al. Expression of TRAIL and TRAIL receptors in colon carcinoma: TRAIL-R1 is an independent prognostic parameter. Clin Cancer Res 2002;8:3734-40.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3734-3740
-
-
Strater, J.1
Hinz, U.2
Walczak, H.3
-
20
-
-
33748132555
-
TRAIL-receptor expression is an independent prognostic factor for survival in patients with a primary glioblastoma multiforme
-
Kuijlen JM, Mooij J J, Platteel I, et al.TRAIL-receptor expression is an independent prognostic factor for survival in patients with a primary glioblastoma multiforme. J Neurooncol 2006;78:161-71.
-
(2006)
J Neurooncol
, vol.78
, pp. 161-171
-
-
Kuijlen, J.M.1
Mooij, J.J.2
Platteel, I.3
-
21
-
-
0035844129
-
MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors
-
Tran SE, Holmstrom TH, Ahonen M, Kahari VM, Eriksson JE. MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors. J Biol Chem 2001;276:16484-90.
-
(2001)
J Biol Chem
, vol.276
, pp. 16484-16490
-
-
Tran, S.E.1
Holmstrom, T.H.2
Ahonen, M.3
Kahari, V.M.4
Eriksson, J.E.5
-
22
-
-
24744462114
-
Tumor necrosis factor-related apoptosis-inducing ligand-mediated proliferation of tumor cells with receptor-proximal apoptosis defects
-
Baader E. Toloczko A, Fuchs U, et al. Tumor necrosis factor-related apoptosis-inducing ligand-mediated proliferation of tumor cells with receptor-proximal apoptosis defects. Cancer Res 2005;65:7888-95.
-
(2005)
Cancer Res
, vol.65
, pp. 7888-7895
-
-
Baader, E.1
Toloczko, A.2
Fuchs, U.3
-
23
-
-
0035340285
-
The role of NF-κB in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of melanoma cells
-
Franco AV, Zhang XD, Van Berkel E, et al. The role of NF-κB in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of melanoma cells. J Immunol 2001;166:5337-45.
-
(2001)
J Immunol
, vol.166
, pp. 5337-5345
-
-
Franco, A.V.1
Zhang, X.D.2
Van Berkel, E.3
-
24
-
-
0031406386
-
Death receptor 5, a new member of theTNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway
-
Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. Death receptor 5, a new member of theTNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway. Immunity 1997;7:821-30.
-
(1997)
Immunity
, vol.7
, pp. 821-830
-
-
Chaudhary, P.M.1
Eby, M.2
Jasmin, A.3
Bookwalter, A.4
Murray, J.5
Hood, L.6
-
25
-
-
0035963273
-
Constitutive activation of nuclear factor-κB prevents TRAIL-induced apoptosis in renal cancer cells
-
Oya M, Ohtsubo M, Takayanagi A, Tachibana M, Shimizu N, Murai M. Constitutive activation of nuclear factor-κB prevents TRAIL-induced apoptosis in renal cancer cells. Oncogene 2001;20:3888-96.
-
(2001)
Oncogene
, vol.20
, pp. 3888-3896
-
-
Oya, M.1
Ohtsubo, M.2
Takayanagi, A.3
Tachibana, M.4
Shimizu, N.5
Murai, M.6
-
26
-
-
0035067368
-
Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-κB
-
Ravi R, Bedi GC, Engstrom LW, et al. Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-κB. Nat Cell Biol 2001;3:409-16.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 409-416
-
-
Ravi, R.1
Bedi, G.C.2
Engstrom, L.W.3
-
27
-
-
33845221022
-
TRAIL promotes metastasis of human pancreatic ductal adenocarcinoma
-
Trauzold A, Siegmund D, Schniewind B, et al.TRAIL promotes metastasis of human pancreatic ductal adenocarcinoma. Oncogene 2006;25:7434-9.
-
(2006)
Oncogene
, vol.25
, pp. 7434-7439
-
-
Trauzold, A.1
Siegmund, D.2
Schniewind, B.3
-
28
-
-
33644801980
-
Trail induces cell migration and invasion in apoptosis-resistant cholangiocarcinoma cells
-
Ishimura N, Isomoto H, Bronk SF, Gores GJ. Trail induces cell migration and invasion in apoptosis-resistant cholangiocarcinoma cells. Am J Physiol 2006;290:G129-36.
-
(2006)
Am J Physiol
, vol.290
-
-
Ishimura, N.1
Isomoto, H.2
Bronk, S.F.3
Gores, G.J.4
-
29
-
-
0013583837
-
Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
-
Zhang XD, Franco A, Myers K, Gray C, Nguyen T, Hersey P. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res 1999;59:2747-53.
-
(1999)
Cancer Res
, vol.59
, pp. 2747-2753
-
-
Zhang, X.D.1
Franco, A.2
Myers, K.3
Gray, C.4
Nguyen, T.5
Hersey, P.6
-
30
-
-
34249303745
-
TNM staging system for renal-cell carcinoma: Current status and future perspectives
-
Ficarra V, Galfano A, Mancini M, Martignoni G, Artibani W. TNM staging system for renal-cell carcinoma: current status and future perspectives. Lancet Oncol 2007;8:554-8.
-
(2007)
Lancet Oncol
, vol.8
, pp. 554-558
-
-
Ficarra, V.1
Galfano, A.2
Mancini, M.3
Martignoni, G.4
Artibani, W.5
-
31
-
-
28844484134
-
Renal-cell carcinoma
-
Cohen H, McGovern F. Renal-cell carcinoma. N Engl J Med 2005;353:2477-90.
-
(2005)
N Engl J Med
, vol.353
, pp. 2477-2490
-
-
Cohen, H.1
McGovern, F.2
-
32
-
-
26844531391
-
Biochemical and molecular markers in renal cell carcinoma: An update and future prospects
-
Kashyap MK, Kumar A, Emelianenko N, et al. Biochemical and molecular markers in renal cell carcinoma: an update and future prospects. Biomarkers 2005;10:258-94.
-
(2005)
Biomarkers
, vol.10
, pp. 258-294
-
-
Kashyap, M.K.1
Kumar, A.2
Emelianenko, N.3
-
33
-
-
54249150411
-
Decoy Receptor 3 is a prognostic factor in renal cell cancer
-
Macher-Goeppinger S, Aulmann S, Wagener N, et al. Decoy Receptor 3 is a prognostic factor in renal cell cancer. Neoplasia 2008;10:1049-56.
-
(2008)
Neoplasia
, vol.10
, pp. 1049-1056
-
-
Macher-Goeppinger, S.1
Aulmann, S.2
Wagener, N.3
-
34
-
-
0037872265
-
Apoptosis induction in renal cell carcinoma by TRAIL and -γ-radi-ation is impaired by deficient caspase-9 cleavage
-
Ramp U, Caliskan E, Mahotka C, et al. Apoptosis induction in renal cell carcinoma by TRAIL and -γ-radi-ation is impaired by deficient caspase-9 cleavage. Br J Cancer 2003;88:1800-7.
-
(2003)
Br J Cancer
, vol.88
, pp. 1800-1807
-
-
Ramp, U.1
Caliskan, E.2
Mahotka, C.3
-
35
-
-
0036606414
-
Induction and regulation of tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand-mediated apoptosis in renal cell carcinoma
-
Griffith TS. Fialkov JM, Scott DL, et al. Induction and regulation of tumor necrosis factor-related apoptosis-inducing ligand/Apo-2 ligand-mediated apoptosis in renal cell carcinoma. Cancer Res 2002;62:3093-9.
-
(2002)
Cancer Res
, vol.62
, pp. 3093-3099
-
-
Griffith, T.S.1
Fialkov, J.M.2
Scott, D.L.3
-
36
-
-
0033710429
-
Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan
-
Dejosez M, Ramp U, Mahotka C, et al. Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan. Cell Death Differ 2000;7:1127-36.
-
(2000)
Cell Death Differ
, vol.7
, pp. 1127-1136
-
-
Dejosez, M.1
Ramp, U.2
Mahotka, C.3
-
37
-
-
34147189664
-
Enhancement of death receptor 4 mediated apoptosis and cytotoxicity in renal cell carcinoma cells by sub-toxic concentrations of doxorubicin
-
Jin X,Wu XX, Abdel-Muneem Noun MA, Kakehi Y. Enhancement of death receptor 4 mediated apoptosis and cytotoxicity in renal cell carcinoma cells by sub-toxic concentrations of doxorubicin. J Urol 2007;177:1894-9.
-
(2007)
J Urol
, vol.177
, pp. 1894-1899
-
-
Jin, X.1
Wu, X.X.2
Abdel-Muneem Noun, M.A.3
Kakehi, Y.4
-
38
-
-
0037457474
-
Enhancement of TRAIL/Apo2L-mediated apoptosis by adriamycin through inducing DR4 and DR5 in renal cell carcinoma cells
-
Wu XX, Kakehi Y, Mizutani Y, et al. Enhancement of TRAIL/Apo2L-mediated apoptosis by adriamycin through inducing DR4 and DR5 in renal cell carcinoma cells. Int J Cancer 2003;104:409-17.
-
(2003)
Int J Cancer
, vol.104
, pp. 409-417
-
-
Wu, X.X.1
Kakehi, Y.2
Mizutani, Y.3
-
39
-
-
0037444380
-
-
Asakuma J, Sumitomo M, AsanoT, AsanoT, Haya-kawa M. Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitax-el. Cancer Res 2003;63:1365-70.
-
Asakuma J, Sumitomo M, AsanoT, AsanoT, Haya-kawa M. Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitax-el. Cancer Res 2003;63:1365-70.
-
-
-
-
40
-
-
7044240646
-
Cooperation of betulinic acid and TRAIL to induce apoptosis in tumor cells
-
Fulda S, Jeremias I, Debatin KM. Cooperation of betulinic acid and TRAIL to induce apoptosis in tumor cells. Oncogene 2004;23:7611-20.
-
(2004)
Oncogene
, vol.23
, pp. 7611-7620
-
-
Fulda, S.1
Jeremias, I.2
Debatin, K.M.3
-
41
-
-
21044441651
-
HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo
-
Pukac L, Kanakaraj P, Humphreys R, et al. HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo. Br J Cancer 2005;92:1430-41.
-
(2005)
Br J Cancer
, vol.92
, pp. 1430-1441
-
-
Pukac, L.1
Kanakaraj, P.2
Humphreys, R.3
-
42
-
-
17444404554
-
Reduction of the antiapop-totic protein cFLIP enhances the susceptibility of human renal cancer cells to TRAIL apoptosis
-
Brooks AD, Sayers TJ. Reduction of the antiapop-totic protein cFLIP enhances the susceptibility of human renal cancer cells to TRAIL apoptosis. Cancer Immunol Immunother 2005;54:499-505.
-
(2005)
Cancer Immunol Immunother
, vol.54
, pp. 499-505
-
-
Brooks, A.D.1
Sayers, T.J.2
-
43
-
-
34247862306
-
Overexpression of XIAP expression in renal cell carcinoma predicts a worse prognosis
-
Mizutani Y, Nakanishi H, Li YN, et al. Overexpression of XIAP expression in renal cell carcinoma predicts a worse prognosis. Int J Oncol 2007;30:919-25.
-
(2007)
Int J Oncol
, vol.30
, pp. 919-925
-
-
Mizutani, Y.1
Nakanishi, H.2
Li, Y.N.3
-
44
-
-
20044376659
-
Down-regulation of Smac/DIABLO expression in renal cell carcinoma and its prognostic significance
-
Mizutani Y, Nakanishi H, Yamamoto K, et al. Down-regulation of Smac/DIABLO expression in renal cell carcinoma and its prognostic significance. J Clin Oncol 2005;23:448-54.
-
(2005)
J Clin Oncol
, vol.23
, pp. 448-454
-
-
Mizutani, Y.1
Nakanishi, H.2
Yamamoto, K.3
|