Inhibition of human P450 enzymes by natural extracts used in traditional medicine

Phytotherapy Research

Volumn 23, Issue 2, 2009, Pages 279-282

  Rodeiro, Idania ^a   Donato, María T ^b,c   Jimenez, Nuria ^c   Garrido, Gabino ^a   Molina Torres, Jorge ^d   Menendez, Roberto ^e   Castell, José V ^b,c   Gómez Lechón, María J ^c  

^a Centro de Quimica Farmaceutica   (Cuba)

^b UNIVERSITY OF VALENCIA   (Spain)

^c HOSPITAL UNIVERSITARIO LA FE   (Spain)

^d DEPARTAMENTO DE INGENIERÍA GENÉTICA   (Mexico)

^e CITMA   (Cuba)

Author keywords

CYP1A1 2; CYP2D6; CYP3A4; Human liver microsomes; Medicinal plants

Indexed keywords

AFFININ; AMIDE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; HELIOPSIS LONGIPES EXTRACT; MANGIFERA INDICA EXTRACT; MANGIFERIN; PLANT EXTRACT; THALASSIA TESTUDINUM EXTRACT; UNCLASSIFIED DRUG; CYTOCHROME P450; FLAVONOID; N ISOBUTYL 2E DECENAMIDE; N-ISOBUTYL-2E-DECENAMIDE; PHENOL DERIVATIVE; POLYPHENOLS;

ARTICLE; CATALYSIS; CONCENTRATION RESPONSE; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; LIVER MICROSOME; TRADITIONAL MEDICINE; ASTERACEAE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FEMALE; HERB DRUG INTERACTION; HYDROCHARITACEAE; MALE; MANGO; MEDICINAL PLANT; METABOLISM; PHYTOTHERAPY;

HELIOPSIS LONGIPES; MANGIFERA INDICA; THALASSIA TESTUDINUM;

ASTERACEAE; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; FLAVONOIDS; HERB-DRUG INTERACTIONS; HUMANS; HYDROCHARITACEAE; MALE; MANGIFERA; MEDICINE, TRADITIONAL; MICROSOMES, LIVER; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; POLYUNSATURATED ALKAMIDES;

EID: 59449087253     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2613     Document Type: Article

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