MRI-Based CFD analysis of flow in a human left ventricle: Methodology and application to a healthy heart

Annals of Biomedical Engineering

Volumn 37, Issue 3, 2009, Pages 503-515

  Schenkel, Torsten ^a   Malve, Mauro ^a   Reik, Michael ^a   Markl, Michael ^b   Jung, Bernd ^b   Oertel, Herbert ^a  

^a UNIVERSITY OF KARLSRUHE   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Blood flow simulation; Computational fluid dynamics; In vivo; Magnetic resonance imaging; Modeling; MRI; MRI flux; Patient specific; Ventricle

Indexed keywords

ATOMS; BLOOD; COMPUTATIONAL FLUID DYNAMICS; DYNAMICS; FLUID DYNAMICS; HEMODYNAMICS; MAGNETIC RESONANCE; MAGNETIC RESONANCE IMAGING; RESONANCE; THREE DIMENSIONAL; VALVES (MECHANICAL);

BLOOD FLOW SIMULATION; IN VIVO; MODELING; MRI; MRI FLUX; PATIENT SPECIFIC; VENTRICLE;

FLOW SIMULATION;

ARTICLE; BIOLOGICAL MODEL; BLOOD FLOW VELOCITY; BLOOD PRESSURE; COMPUTER ASSISTED DIAGNOSIS; COMPUTER SIMULATION; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE; HISTOLOGY; HUMAN; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; PULSATILE FLOW;

BLOOD FLOW VELOCITY; BLOOD PRESSURE; COMPUTER SIMULATION; HEART VENTRICLES; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MODELS, CARDIOVASCULAR; PULSATILE FLOW; VENTRICULAR FUNCTION, LEFT;

EID: 59449085504     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-008-9627-4     Document Type: Article

References (45)

1. D. J. Atkinson R. R. Edelman 1991 Cineangiography of the heart in a single breath hold with a segmented turboflash sequence Radiology 178 357 360
2. L. Axel 1984 Blood flow effects in magnetic resonance imaging Am. J. Roentgenol. 143 6 1157 1166
3. B. Baccani F. Domenichini G. Pedrizzetti 2002 Vortex dynamics in a model left ventricle during filling Eur. J. Mech. B/Fluids 21 527 543
4. B. Baccani F. Domenichini G. Pedrizzetti 2003 Model and influence of mitral valve opening during the left ventricular filling J. Biomech. 36 355 361
5. B. Baccani F. Domenichini G. Pedrizzetti G. Tonti 2002 Fluid dynamics of the left ventricular filling in dilated cardiomyopathy J. Biomech. 35 5 665 671
6. G. Bolzon L. Zovatto G. Pedrizzetti 2003 Birth of three-dimensionality in a pulsed jet through a circular orifice J. Fluid Mech. 493 209 218
7. B. Chahboune J. M. Crolet 1998 Numerical simulation of the blood-wall interaction in the human left ventricle Eur. Phys. J. Appl. Phys. 2 291 297
8. Y. Cheng H. Oertel T. Schenkel 2004 Fluid-structure coupled cfd simulation of the left ventricular flow during filling phase Ann. Biomed. Eng. 33 5 567 576
9. F. Domenichini G. Pedrizzetti B. Baccani 2005 Three-dimensional filling flow into a model left ventricle J. Fluid Mech. 539 179 198
10. T. Ebbers L. Wigstrï A. F. Bolger B. Wranne M. Karlsson 2002 Noninvasive measurement of time-varying three-dimensional relative pressure fields within the human heart J. Biomech. Eng. 124 288 293
11. Ferziger, J. and M. Peric. Computational Methods for Fluid Dynamics. Berlin: Springer, 1997.
12. D. Geiger A. Gupta L. A. Costa J. Vlontzos 1995 Dynamic programming for detection, tracking and matching deformable contours IEEE Trans. PAMI 17 3 294 302
13. J. Hennig 1999 K-space sampling strategies Eur. Radiol. 9 1020 1031
14. P. J. Hunter A. J. Pullan B. H. Smaill 2003 Modeling total heart function Annu. Rev. Biomed. Eng. 5 147 177
15. Jolly, M.-P. Combining edge, region and shape information to segment the left ventricle in cardiac mr images. In: MICCAI, 2001, pp. 482-490.
16. P. J. Kilner G.-Z. Yang A. J. Wilkes R. H. Mohiaddin D. N. Firmin M. H. Yacoub 2000 Asymmetric redirection of flow through the heart Nature 404 759 761
17. W. Y. Kim P. G. Walker E. M. Pedersen J. K. Poulsen S. Oyre K. Houlind A. P. Yoganathan 1995 Left ventricular blood flow patterns in normal subjects: a quantitative analysis by three-dimensional magnetic resonance velocity mapping JACC 26 1 224 238
18. J. D. Lemmon A. P. Yoganathan 2000 Computational modeling of left herat diastolic function: examination of ventricluar dysfunction J. Biomech. Eng. 122 297 303
19. J. D. Lemmon A. P. Yoganathan 2000 Three-dimensional computational model of left heart diastolic function with fluid-structure interaction J. Biomech. Eng. 122 109 117
20. J. A. Lima M. Y. Desai 2004 Cardiovascular magnetic resonance imaging: current and emerging applications J. Am. Coll. Cardiol. 44 6 1164 1171
21. Q. Long R. Merrifield G. Z. Yang X. Y. Xu P. J. Kilner D. N. Firmin 2003 The influence of inflow boundary conditions on intra left ventricle flow predictions J. Biomech. Eng. 125 922 927
22. C. H. Lorenz E. S. Walker V. L. Morgan S. S. Klein T. P. Graham Jr. 1999 Normal human right and left ventricular mass, systolic function, and gender differences by cine magnetic resonance imaging J. Cardiovasc. Magn. Reson. 1 7 21
23. D. M. [tmp] McQueen C. Peskin 1997 Shared-memory parallel vector implementation of the immersed boundary method for the computation of blood flow in the beating mammalian heart J. Supercomput. 11 3 213 236
24. D. M. [tmp] McQueen C. Peskin 2000 A three-dimensional computer model of the human heart for studying cardiac fluid dynamics Comput. Graph. 34 56 60
25. E. N. Mortensen W. A. Barrett 1998 Interactive segmentation with intelligent scissors Graph. Models Image Process. 60 5 349 384
26. M. Nakamura S. Wada T. Mikami A. Kitabatake T. Karino 2003 Computational study on the evolution of an intraventricular vortical flow during early diastole for the interpretation of color m-mode doppler echocardiogramms Biomech. Model. Mechanobiol. 2 59 72
27. M. P. Nash P. J. Hunter 2000 Computational mechanics of the heart: from tissue structure to ventricular function J. Elast. 61 1/3 113 141
28. Naujokat, E., and U. Kiencke. Neuronal and hormonal cardiac control processes in a model of the human circulatory system. Int. J. Bioelectromagn. 2(2), 2000.
29. D. Noble 2002 Modelling the heart: from genes to cells to the whole organ Science 295 1678 1682
30. Pedrizzetti, G., and F. Domenichini. Nature optimizes the swirling flow in the human left ventricle. Phys. Rev. Lett. 95:108101, 2005.
31. N. J. Pelc R. J. Herfkens A. Shimakawa D. R. Enzmann 1991 Phase contrast cine magnetic resonance imaging Magn. Reson. Q. 7 4 229 254
32. K. Perktold M. Prosi H. Florian 2003 Computational models of arterial flow and mass transport CISM Courses Lect. 446 73 136
33. Peskin, C. S., and D. M. McQueen. Fluid dynamics of the heart and its valves, case studies in mathematical modeling, In: Ecology, Physiology and Cell Biology. New Jersey: Pretice-Hall, 1996, pp. 309-337.
34. S. A. Rebergen E. E. van der Wall J. Doornbos A. de Roos 1993 Magnetic resonance measurement of velocity and flow: technique, validation, and cardiovascular applications Am. Heart J. 126 6 1439 1456
35. N. R. Saber A. D. Gosman N. B. Wood P. J. Kilner C. L. Charrier D. N. Firmin 2001 Computational flow modeling of the left ventricle based on in vivo mri data: Initial experience Ann. Biomed. Eng. 29 4 275 283
36. N. R. Saber N. B. Wood A. D. Gosman R. D. Merrifield G. Z. Yang C. L. Charrier P. D. Gatehouse D. N. Firmin 2003 Progress towards patient-specific computational flow modeling of the left heart via combination of magnetic resonance imaging with computational fluid dynamics Ann. Biomed. Eng. 31 1 42 52
37. Schenk, A., G. Prause, and H. Peitgen. Local cost computation for efficient segmentation of 3d objects with live wire. In: Proceedings of SPIE, edited by M. Sonka and K. M. Hanson. SPIE, Vol. 4322, 2001, pp. 1357-1364.
38. R. T. Schoephoerster C. L. Silva G. Ray 1994 Evaluation of ventricular function based on simulated systolic flow dynamics computed from regional wall motion J. Biomech. 27 125 136
39. Stalling, D., and H.-C. Hege. Intelligent scissors for medical image segmentation. In: Tagungsband zum 4. Freiburger Workshop: Digitale Bildverarbeitung in der Medizin, edited by B. Arnolds, H. Mueller, T. Saupe, and D. Tolxdorf, 1996, pp. 32-36.
40. Taylor, T. W., H. Okino, and T. Yamaguchi. Three-dimensional analysis of left ventricular ejection using computational dynamics. J. Biomech. Eng. 116:127-130, 1994.
41. Vesier, C., J. D. Lemmon, R. A. Levine, and A. P. Yoganathan. A three-dimensional computational model of a thin-walled left ventricle. In: Proceedings on IEEE Supercomputing '92, 16-20 November, 1992, pp. 73-82.
42. J. A. Vierendeels K. Riemslagh E. Dick 2000 Computer simulation of intraventricular flow and pressure gradients during diastole J. Biomech. Eng. 122 667 674
43. J. A. Vierendeels K. Riemslagh E. Dick P. Verdonck 1999 Computer simulation of left ventricular filling flow Comput. Cardiol. 26 177 180
44. H. Watanabe T. Hisada S. Sugiura J. Okada H. Fukunari 2002 Computer simulation of blood flow, left ventricular wall motion and their interrelationship by fluid-structure interaction finite element method JSME Int. J. Ser. C- Mech. Syst. Mach. Elem. Manufact. 45 4 1003 1012
45. H. Watanabe S. Sugiura H. Kafuku T. Hisada 2004 Multiphysics simulation of left ventricular filling dynamics using fluid-structure interaction finite element method Biophys. J. 87 2074 2085