Evidence for the presence of R250G mutation at the ATPase domain of topoisomerase II in an arsenite-resistant Leishmania donovani exhibiting a differential drug inhibition profile

International Journal of Antimicrobial Agents

Volumn 33, Issue 1, 2009, Pages 80-85

  Singh, Gaganmeet ^a   Thakur, Meghna ^b   Chakraborti, Pradip K ^b   Dey, Chinmoy S ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

Author keywords

Actinomycin D; Doxorubicin; Leishmania donovani; Novobiocin; Pentamidine; Topoisomerase II

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ARSENITE SODIUM; DACTINOMYCIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; MILTEFOSINE; NOVOBIOCIN; PENTAMIDINE;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG SENSITIVITY; ENZYME ACTIVITY; GENE MUTATION; GENE SEQUENCE; LEISHMANIA DONOVANI; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; ARSENITES; DNA TOPOISOMERASES, TYPE II; DRUG RESISTANCE; LEISHMANIA DONOVANI; MOLECULAR SEQUENCE DATA; PARASITIC SENSITIVITY TESTS; POINT MUTATION; PROTOZOAN PROTEINS;

EID: 59349117685     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2008.06.034     Document Type: Article

References (13)

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