Visceral fat and adiponectin: Associations with insulin resistance are tissue-specific in women

Metabolic Syndrome and Related Disorders

Volumn 7, Issue 1, 2009, Pages 61-67

  Coker, Robert H ^a,c,d   Williams, Rick H ^a   Yeo, Sophie E ^a   Kortebein, Patrick M ^c   Bodenner, Don L ^a,c   Kern, Philip A ^b,c   Evans, William J ^a,c  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; GLUCAGON; INSULIN; OCTREOTIDE; ADIPOQ PROTEIN, HUMAN; GLUCOSE BLOOD LEVEL;

ADIPOSE TISSUE; ADULT; ARTICLE; BODY FAT DISTRIBUTION; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DUAL ENERGY X RAY ABSORPTIOMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCONEOGENESIS; HUMAN; INSULIN RESISTANCE; OBESITY; PRIORITY JOURNAL; BLOOD; BODY MASS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; INTRAABDOMINAL FAT; LIVER; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHOTON ABSORPTIOMETRY; POSTMENOPAUSE; SKELETAL MUSCLE; TIME;

ABSORPTIOMETRY, PHOTON; ADIPONECTIN; ADIPOSITY; BLOOD GLUCOSE; BODY MASS INDEX; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCAGON; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; INSULIN RESISTANCE; INTRA-ABDOMINAL FAT; LIVER; MIDDLE AGED; MUSCLE, SKELETAL; OBESITY; OCTREOTIDE; POSTMENOPAUSE; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 59349114898     PISSN: 15404196     EISSN: None     Source Type: Journal    
DOI: 10.1089/met.2008.0035     Document Type: Article

References (42)

1. Ivy JL, Zderic TW, Fogt DL: Prevention and treatment of non-insulin-dependent diabetes mellitus. Exerc Sport Sci Rev 1999;27:1-35.
2. Tchernof A, Desmeules A, Richard C, Laberge P, Daris M, Mailloux J, Rheaume C, Dupont C: Ovarian hormone status and abdominal visceral adipose tissue metabolism. J Clin Endocrinol Metab 2004;89:3425-3430.
3. Carey VJ, Walters EE, Colditz GA, Solomon CG, Willett WC, Rosner BA, Speizer FE, Manson JE: Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses' Health Study. Am J Epidemiol 1997:145:614-619.
4. Lemieux S, Prud'homme D, Bouchard C, Tremblay A, Despres JP: Sex differences in the relation of visceral adipose tissue accumulation to total body fatness. Am J Clin Nutr 1993;58:463-467.
5. Williams MJ, Hunter GR, Kekes-Szabo T, Trueth MS, Snyder S, Berland L, Blandeau T: Intra-abdominal adipose tissue cut-points related to elevated cardiovascular disease risk in women. Int J Obes Relat Metab Disord 1996;20:613-617.
6. Nielsen S, Guo Z, Johnson CM, Hensrud DD, Jensen MD: Splanchnic lipolysis in human obesity. J Clin Invest 2004;113:1582-1588.
7. Bock G, Chittilapilly, Basu R, Toffolo G, Cobelli C, Chandramouli, Landau B, Rizza RA: Contribution of hepatic and extrahepatic insulin resistance to the pathogenesis of impaired fasting glucose: role of increased rates of gluconeogenesis. Diabetes 2007;56:1703-1709.
8. Folsom AR, Kushi LH, Anderson KE, Mink PJ, Olson JE, Hong CP, Sellers TA, Lazovich D, Prineass RJ: Associations of general and abdominal obesity with multiple health outcomes in older women. Arch Intern Med 2000;160:2117-2128.
9. Bajaj M, Suraamornkul S, Piper P, Hardies LJ, Glass L, Cersosimo E, Pratipanawatr T, Miyazaki Y, Defronzo RA: Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients. J Clin Endocrinol Metab 2004;89:200[[en dash]]]206.
10. Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, Bihain BE, Lodish HF: Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 2001;98:2005-2010.
11. Berg AH, Combs TP, Du X, Brownlee M, Scherer PE: The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001;7:947-953.
12. Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang CC, Itani SI, Lodish HF, Rudernman NB: Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci USA 2002;10:16309-16313.
13. Rolland YM, Perry HMr, Patrick P, Banks WA, Morley JE: Leptin and adiponectin levels in middle-aged postmenopausal women: associations with lifestyle habits, hormones, and inflammatory markers - a cross-sectional study. Metabolism 2006;55:1630-1636.
14. Goodarzi MT, Babaahmadi-Rezaei H, Kadkhodaei-Eliaderani M, Haddainezhad S: Relationship of serum adiponectin with blood lipids, HbA(1)c, and hs-CRP in type II diabetic postmenopausal women. J Clin Lab Anal 2007;21:197-200.
15. Association AD: Diagnosis and classification of diabetes mellitus. Diabetes Care 2006; ;29:S43-S48.
16. Finegood DT, Bergman RN, Vranic M: Estimation of endogenous glucose production dring hyperinsulinemic-euglycemic glucose clamps. Diabetes 1987;36:914[[en dash]]]924.
17. DeFronzo RA, Tobin JD, Andres R: Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979;237:E214[[en dash]]]E223.
18. Toth MJ, Sites CK, Cefalu WT, Matthews DE, Poehlman ET: Determinants of insulin-stimulated glucose disposal in middle aged, premenopausal women. Am J Physiol Endocrinol Metab 2001;281:E113[[en dash]]]E121.
19. Steele R: Influences of glucose loading and injected insulin on hepatic glucose output. Ann NY Acad Sci 1959;82:420-430.
20. Starling RD, Toth MJ, Matthews DE, Poehlman ET: Energy requirements and physical activity of older free-living African-Americans: a doubly labeled water study. J Clin Endocrinol Metab 1998;83:1529-1534.
21. Bouchard C, Despres JP, Mauriege P: Genetic and non-genetic determinants of regional fat distribution. Endocr Rev 1993;14:72-93.
22. Bjorntorp P. Metabolic abnormalities in visceral obesity. Ann Med 1992 24:3-5
23. Ostman J, Arner P, Engfeldt P, Kager L: Regional differences in the control of lipolysis in human adipose tissue. Metabolism 1979;28:1198-1205
24. Williamson JR: Mechanism for the stimulation in vivo of hepatic gluconeogenesis by glucacgon. Biochem J 1966;101:11C-14C.
25. Clarke SD: Polyunsaturated fatty acid regulation of gene transcription: a mechanism to improve energy balance and insulin resistance. Br J Nutr 2000;83:S59-S66.
26. Oakes ND, Cooney GJ, Camilleri M, Chisholm DJ, Kraegen EW: Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding. Diabetes 1997;46:1768-1774.
27. Mittelman SD, Van Citters GW, Kim P, Davis DA, Dea MK, Hamilton-Wessler M, Bergman RN: Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enchanced beta-cell response. Diabetes 2000;49:2116-2125.
28. Hotamisligil GS: Mechanisms of TNF-alpha-induced insulin resistance. Exp Clin Endocrinol Diabetes 1999;107:119-125.
29. Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Patel HR, Ahima RS, Lazar MA: The hormone resistin links obesity to diabetes. Nature 2001;409:307-312
30. Bajaj M, Suraamornkul S, Piper P, Hardies LJ, Glass L, Cersosimo E, Pratipanawatr T, Miyachi H, Defronzo RA: Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients. J Clin Endocrinol Metab 2004;89:200-206.
31. Goodpaster BH, Thaete FL, Simoneau JA, Kelley DE: Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independent of visceral fat. Diabetes 1997;46:1579-1585.
32. Ross R, Fortier L, Hudson R: Separate associations between visceral and subcutaneous adipose tissue distribution, insulin and glucose levels in obese women. Diabetes Care 1996;19:1404-1411.
33. Despres JP, Nadeau A, Tremblay A, Ferland M, Mooriani S, Lupien PJ, Theriault G, Pinault S, Bouchard C: Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women. Diabetes 1989;38:304-309.
34. Yeo SE, Hays NP, Dennis RA, Kortebein PM, Sullivan DH, Evans WJ, Coker RH: Fat distribution and glucose metabolism in older, obese men and women. J Gerontol A Biol Sci Med Sci 2007;62:1393-1401.
35. Zamboni M, Armellini F, Milani MP, DeMarchi M, Todesco T, Robbi R, Bergamo-Andreis IA, Bosello O: Body fat distribution in pre- and post-menopausal women: metabolic and anthropometric variables and their inter-relationships. Int J Obes Relat Metab Disord 1992;16:495-504.
36. Monzillo LU, Hamby O: Evaluation of insulin sensitivity in clinical practice and in research settings. Nutrit Rev 2003;61:397-412.
37. Kelley DE, Thaete FL, Troost F, Huwe T, Goodpaster BH: Subdivisions of subcutaneous abdominal adipose tissue and insulin resistance Am J Physiol Endocrinol Metab 2000;278:E941-E948.
38. Yokoyama H, Emoto M, Mori K, Araki T, Teramura M, Koyama H, Shoji T, Inaba M, Nishizawa Y: Plasma adiponectin level is associated with insulin-stimulated nonoxidative glucose disposal. J Clin Endocrinol Metab 2006;91:290-294.
39. Abbasi F, Chu JW, Lamendola C, McLaughlin T, Hayden J, Reaven GM, Reaven PD: Discrimination between obesity and insulin resistance in the relationship with adiponectin. Diabetes 2004;53:585-590.
40. Kern PA, DiGregorio GB, Lu T, Rasouli N, Ranganathan G: Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. Diabetes 2003;52:1779-1785.
41. Ryan AS, Berman DM, Nicklas BJ, Sinha M, Gingerich RL, Meneilly GS, Egan JM, Elahi D: Plasma adiponectin and leptin levels, body composition, and glucose utilization in adult women with wide rangs of age and obesity. Diabetes Care 2003;26:2383-2388
42. Goodpaster BH, Krishnaswami S, Resnick H, Kelley DE, Haggerty C, Harris TB, Schwartz AV, Kritchevsky S, Newman AB: Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and women. Diabetes Care 2003;26:372-379.