Role of glutamine administration on T-cell derived inflammatory response after cardiopulmonary bypass

Clinical Nutrition

Volumn 28, Issue 1, 2009, Pages 15-20

  Engel, J M ^a   Pitz, S ^a   Muhling J ^a   Menges, T ^a   Martens, F ^a   Kwapisz, M ^a   Hempelmann, G ^a  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

Author keywords

Cardiopulmonary bypass; Glutamine; Interleukin 1; Interleukin 6; Interleukin 8; T helper cells; Tumor necrosis factor

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; DIPEPTAMIN; GLUTAMINE; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AGED; AMINO ACID BLOOD LEVEL; ANESTHESIA INDUCTION; ARTICLE; ARTIFICIAL VENTILATION; CARDIOPULMONARY BYPASS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOUBLE BLIND PROCEDURE; ELECTIVE SURGERY; FEMALE; HEART EJECTION FRACTION; HEART SURGERY; HUMAN; INFLAMMATION; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MITRAL VALVE REPLACEMENT; MULTIPLE ORGAN FAILURE; PERIOPERATIVE PERIOD; POSTOPERATIVE PERIOD; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; T LYMPHOCYTE;

AGED; C-REACTIVE PROTEIN; CARDIOPULMONARY BYPASS; CYTOKINES; DOUBLE-BLIND METHOD; FEMALE; GLUTAMINE; HEART DISEASES; HUMANS; INFLAMMATION; INFUSIONS, INTRAVENOUS; LENGTH OF STAY; MALE; PERIOPERATIVE CARE; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; TH1 CELLS; TH2 CELLS;

EID: 59349093006     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clnu.2008.08.007     Document Type: Article

References (38)

1. Kollef M.H., Wragge T., and Pasque C. Determinants of mortality and multiorgan dysfunction in cardiac surgery patients requiring prolonged mechanical ventilation. Chest 107 (1995) 1395-1401
2. Franke A., Lante W., Fackeldey V., Becker H.P., Thode C., Kuhlmann W.D., et al. Proinflammatory and antiinflammatory cytokines after cardiac operation: different cellular sources at different times. Ann Thorac Surg 74 (2002) 363-370
3. Franke A., Lante W., Fackeldey V., Becker H.P., Kurig E., Zoller L.G., et al. Pro-inflammatory cytokines after different kinds of cardio-thoracic surgical procedures: is what we see what we know?. Eur J Cardiothorac Surg 28 (2005) 569-575
4. Newsholme E.A., and Calder P.C. The proposed role of glutamine in some cells of the immune system and speculative consequences for the whole animal. Nutrition 13 (1997) 728-730
5. Yaqoob P., and Calder P.C. Cytokine production by human peripheral blood mononuclear cells: differential senstivity to glutamine availability. Cytokine 10 (1998) 790-794
6. Parry-Billings M., Baigrie R.J., Lamont P.M., Morris P.J., and Newsholme E.A. Effects of major and minor surgery on plasma glutamine and cytokine levels. Arch Surg 127 (1992) 1237-1240
7. Roth E., Funovics J., Muhlbacher F., Schemper M., Mauritz W., Sporn P., et al. Metabolic disorders in severe abdominal sepsis: glutamine deficiency in skeletal muscle. Clin Nutr (1982) 25-41
8. Oudemans-van Straaten H.M., Bosman R.J., Treskes M., van der Spoel H.J., and Zandstra D.F. Plasma glutamine depletion and patient outcome in acute ICU admissions. Intensive Care Med 27 (2001) 84-90
9. Laffey J.G., Boylan J.F., and Cheng D.C.H. The systemic inflammatory response to cardiac surgery. Implications for the anesthesiologist. Anesthesiology 97 (2002) 215-252
10. Muhling J., Fuchs M., Dehne M.G., Sablotzki A., Menges T., Weber B., and Hempelmann G. Quantitative determination of free intracellular amino acids in single human polymorphonuclear leucocytes. Recent developments in sample preparation and high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl 728 (1999) 157-166
11. Wernerman J. Glutamine-containing TPN: a question of life and death for intensive care unit-patients?. Clin Nutr 17 (1998) 3-6
12. Wallace C., and Keast D. Glutamine and macrophage function. Metabolism 41 (1992) 1016-1020
13. Bossuyt X., Marti G.E., and Fleisher T.A. Comparative analysis of whole blood lysis methods for flow cytometry. Cytometry 30 (1997) 124-133
14. McNerlan S.E., Rea I.M., and Alexander H.D. A whole blood method for measurement of intracellular TNF-alpha, IFN-gamma and IL-2 expression in stimulated CD3+ lymphocytes: differences between young and elderly subjects. Exp Gerontol 37 (2002) 227-234
15. Collins D.P. Cytokine and cytokine receptor expression as a biological indicator of immune activation: important considerations in the development of in vitro model systems. J Immunol Methods 243 (2000) 125-145
16. Grunenfelder J., Zund G., Schoeberlein A., Schmid E.R., Schurr U., Frisullo R., et al. Expression of adhesion molecules and cytokines after coronary artery bypass grafting during normothermic and hypothermic cardiac arrest. Eur J Cardiothorac Surg 17 (2000) 723-728
17. Dehoux M.S., Hernot S., Asehnoune K., Boutten A., Paquin S., Lecon-Malas V., et al. Cardiopulmonary bypass decreases cytokine production in lipopolysaccharide-stimulated whole blood cells: roles of interleukin-10 and the extracorporeal circuit. Crit Care Med 28 (2000) 1721-1727
18. Wan S., LeClerc J.L., Schmartz D., Barvais L., Huynh C.H., Deviere J., et al. Hepatic release of interleukin-10 during cardiopulmonary bypass in steroid-pretreated patients. Am Heart J 133 (1997) 335-339
19. Sbrana S., Parri M.S., De Filippis R., Gianetti J., and Clerico A. Monitoring of monocyte functional state after extracorporeal circulation: a flow cytometry study. Cytometry 58B (2004) 17-24
20. Markewitz A., Lante W., Franke A., Marohl K., Kuhlmann W.D., and Weinhold C. Alterations of cell-mediated immunity following cardiac operations: clinical implications and open questions. Shock 16 Suppl. 1 (2001) 10-15
21. Markewitz A., Faist E., Lang S., Hultner L., Weinhold C., and Reichart B. An imbalance in T-helper cell subsets alters immune response after cardiac surgery. Eur J Cardiothorac Surg 10 (1996) 61-67
22. Majetschak M., Borgermann J., Waydhas C., Obertacke U., Nast-Kolb D., and Schade F.U. Whole blood tumor necrosis factor-alpha production and its relation to systemic concentrations of interleukin 4, interleukin 10, and transforming growth factor-beta1 in multiply injured blunt trauma victims. Crit Care Med 28 (2000) 1847-1853
23. Ertel W., Kremer J.P., Kenney J., Steckholzer U., Jarrar D., Trentz O., et al. Downregulation of proinflammatory cytokine release in whole blood from septic patients. Blood 85 (1995) 1341-1347
24. De Groote D., Zangerle P.F., Gevaert Y., Fassotte M.F., Beguin Y., Noizat-Pirenne F., et al. Direct stimulation of cytokines (IL-1 beta, TNF-alpha, IL-6, IL-2, IFN-gamma and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation. Cytokine 4 (1992) 239-248
25. Goeters C., Wenn A., Mertes N., Wempe C., Van Aken H., Stehle P., et al. Parenteral L-alanyl-L-glutamine improves 6-month outcome in critically ill patients. Crit Care Med 30 (2002) 2032-2037
26. Griffiths R.D., Allen K.D., Andrews F.J., and Jones C. Infection, multiple organ failure, and survival in the intensive care unit: influence of glutamine-supplemented parenteral nutrition on acquired infection. Nutrition 18 (2002) 546-552
27. Wischmeyer P.E., Riehm J., Singleton K.D., Ren H., Musch M.W., Kahana M., et al. Glutamine attenuates tumor necrosis factor-alpha release and enhances heat shock protein 72 in human peripheral blood mononuclear cells. Nutrition 19 (2003) 1-6
28. Lai Y.N., Yeh S.L., Lin M.T., Shang H.F., Yeh C.L., and Chen W.J. Glutamine supplementation enhances mucosal immunity in rats with Gut-Derived sepsis. Nutrition 20 (2004) 286-291
29. Dechelotte P., Hasselmann M., Cynober L., Allaouchiche B., Coeffier M., Hecketsweiler B., et al. L-alanyl-L-glutamine dipeptide-supplemented total parenteral nutrition reduces infectious complications and glucose intolerance in critically ill patients: the French controlled, randomized, double-blind, multicenter study. Crit Care Med 34 (2006) 598-604
30. Garcia-de-Lorenzo A., Zarazaga A., Garcia-Luna P.P., Gonzalez-Huix F., Lopez-Martinez J., Mijan A., et al. Clinical evidence for enteral nutritional support with glutamine: a systematic review. Nutrition 19 (2003) 805-811
31. Coeffier M., Claeyssens S., Hecketsweiler B., Lavoinne A., Ducrotte P., and Dechelotte P. Enteral glutamine stimulates protein synthesis and decreases ubiquitin mRNA level in human gut mucosa. Am J Physiol Gastrointest Liver Physiol 285 (2003) G266-G273
32. De Souza D.A., and Greene L.J. Intestinal permeability and systemic infections in critically ill patients: effect of glutamine. Crit Care Med 33 (2005) 1125-1135
33. Novak F., Heyland D.K., Avenell A., Drover J.W., and Su X. Glutamine supplementation in serious illness: a systematic review of the evidence. Crit Care Med 30 (2002) 2022-2029
34. Heyland D.K., Dhaliwal R., Drover J.W., Gramlich L., and Dodek P. Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. J Parenteral Enter Nutr 27 (2003) 355-373
35. Harig F., Feyrer R., Mahmoud F.O., Blum U., and von der E.J. Reducing the post-pump syndrome by using heparin-coated circuits, steroids, or aprotinin. Thorac Cardiovasc Surg 47 (1999) 111-118
36. Cavaillon J.M. The nonspecific nature of endotoxin tolerance. Trends Microbiol 3 (1995) 320-324
37. Chernoff A.E., Granowitz E.V., Shapiro L., Vannier E., Lonnemann G., Angel J.B., et al. A randomized, controlled trial of IL-10 in humans. Inhibition of inflammatory cytokine production and immune responses. J Immunol 154 (1995) 5492-5499
38. Mengozzi M., and Ghezzi P. Cytokine down-regulation in endotoxin tolerance. Eur Cytokine Netw 4 (1993) 89-98