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Volumn 1788, Issue 2, 2009, Pages 507-513

The role of membrane cholesterol in determining bile acid cytotoxicity and cytoprotection of ursodeoxycholic acid

Author keywords

Cholesterol; Deoxycholic acid cytotoxicity; Membrane dipole potential; Membrane permeability; Turbidity; Ursodeoxycholic acid cytoprotection

Indexed keywords

BILE ACID; CHOLESTEROL; DEOXYCHOLATE SODIUM; LIPOSOME; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; URSODEOXYCHOLIC ACID;

EID: 59249108194     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2008.12.008     Document Type: Article
Times cited : (39)

References (40)
  • 1
    • 0026623067 scopus 로고
    • Bile acid solubility and precipitation in vitro and in vivo: the role of conjugation, pH, and Ca2+ ions
    • Hofmann A.F., and Mysels K.J. Bile acid solubility and precipitation in vitro and in vivo: the role of conjugation, pH, and Ca2+ ions. J. Lipid Res. 33 (1992) 617-626
    • (1992) J. Lipid Res. , vol.33 , pp. 617-626
    • Hofmann, A.F.1    Mysels, K.J.2
  • 2
    • 0030061978 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid protects in vitro models of human colonic cancer cells from cytotoxic effects of hydrophobic bile acids
    • Shekels L.L., Beste J.E., and Ho S.B. Tauroursodeoxycholic acid protects in vitro models of human colonic cancer cells from cytotoxic effects of hydrophobic bile acids. J. Lab. Clin. Med. 127 (1996) 57-66
    • (1996) J. Lab. Clin. Med. , vol.127 , pp. 57-66
    • Shekels, L.L.1    Beste, J.E.2    Ho, S.B.3
  • 3
    • 0036725044 scopus 로고    scopus 로고
    • Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited
    • Paumgartner G., and Beuers U. Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited. Hepatology 36 (2002) 525-531
    • (2002) Hepatology , vol.36 , pp. 525-531
    • Paumgartner, G.1    Beuers, U.2
  • 4
    • 0027179015 scopus 로고
    • Molecular aspects of membrane stabilization by ursodeoxycholate [see comment]
    • Guldutuna S., Zimmer G., Imhof M., Bhatti S., You T., and Leuschner U. Molecular aspects of membrane stabilization by ursodeoxycholate [see comment]. Gastroenterology 104 (1993) 1736-1744
    • (1993) Gastroenterology , vol.104 , pp. 1736-1744
    • Guldutuna, S.1    Zimmer, G.2    Imhof, M.3    Bhatti, S.4    You, T.5    Leuschner, U.6
  • 5
    • 20444471137 scopus 로고    scopus 로고
    • Bile acid induces hydrophobicity-dependent membrane alterations
    • Akare S., and Martinez J.D. Bile acid induces hydrophobicity-dependent membrane alterations. Biochim. Biophys. Acta 1735 (2005) 59-67
    • (2005) Biochim. Biophys. Acta , vol.1735 , pp. 59-67
    • Akare, S.1    Martinez, J.D.2
  • 6
    • 0032525819 scopus 로고    scopus 로고
    • A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation
    • Rodrigues C.M., Fan G., Ma X., Kren B.T., and Steer C.J. A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation. J. Clin. Invest. 101 (1998) 2790-2799
    • (1998) J. Clin. Invest. , vol.101 , pp. 2790-2799
    • Rodrigues, C.M.1    Fan, G.2    Ma, X.3    Kren, B.T.4    Steer, C.J.5
  • 7
    • 0031950282 scopus 로고    scopus 로고
    • Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production
    • Rodrigues C.M., Fan G., Wong P.Y., Kren B.T., and Steer C.J. Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production. Mol. Med. 4 (1998) 165-178
    • (1998) Mol. Med. , vol.4 , pp. 165-178
    • Rodrigues, C.M.1    Fan, G.2    Wong, P.Y.3    Kren, B.T.4    Steer, C.J.5
  • 9
    • 0027998655 scopus 로고
    • Pharmacology of ursodeoxycholic acid, an enterohepatic drug
    • Hofmann A.F. Pharmacology of ursodeoxycholic acid, an enterohepatic drug. Scand. J. Gastroenterol. Suppl. 204 (1994) 1-15
    • (1994) Scand. J. Gastroenterol. Suppl. , vol.204 , pp. 1-15
    • Hofmann, A.F.1
  • 10
    • 14944350350 scopus 로고    scopus 로고
    • Ursodeoxycholic acid can suppress deoxycholic acid-induced apoptosis by stimulating Akt/PKB-dependent survival signaling
    • Im E., Akare S., Powell A., and Martinez J.D. Ursodeoxycholic acid can suppress deoxycholic acid-induced apoptosis by stimulating Akt/PKB-dependent survival signaling. Nutr. Cancer 51 (2005) 110-116
    • (2005) Nutr. Cancer , vol.51 , pp. 110-116
    • Im, E.1    Akare, S.2    Powell, A.3    Martinez, J.D.4
  • 11
    • 0028351832 scopus 로고
    • Ursodeoxycholate conjugates protect against disruption of cholesterol-rich membranes by bile salts
    • Heuman D.M., and Bajaj R. Ursodeoxycholate conjugates protect against disruption of cholesterol-rich membranes by bile salts. Gastroenterology 106 (1994) 1333-1341
    • (1994) Gastroenterology , vol.106 , pp. 1333-1341
    • Heuman, D.M.1    Bajaj, R.2
  • 12
    • 0032740784 scopus 로고    scopus 로고
    • Lipid composition of hepatocyte plasma membranes from geese overfed with corn
    • Cazeils J.L., Bouillier-Oudot M., Auvergne A., Candau M., and Babile R. Lipid composition of hepatocyte plasma membranes from geese overfed with corn. Lipids 34 (1999) 937-942
    • (1999) Lipids , vol.34 , pp. 937-942
    • Cazeils, J.L.1    Bouillier-Oudot, M.2    Auvergne, A.3    Candau, M.4    Babile, R.5
  • 13
    • 0242684707 scopus 로고    scopus 로고
    • Isolation of human small intestinal brush border membranes using polyethylene glycol and effect of exposure to various oxidants in vitro
    • Prabhu R.B., Perakath, and Balasubramanian K.A. Isolation of human small intestinal brush border membranes using polyethylene glycol and effect of exposure to various oxidants in vitro. Dig. Dis. Sci. 48 (2003) 995-1001
    • (2003) Dig. Dis. Sci. , vol.48 , pp. 995-1001
    • Prabhu, R.B.1    Perakath2    Balasubramanian, K.A.3
  • 14
    • 0030757379 scopus 로고    scopus 로고
    • Effect of lipid structure on the dipole potential of phosphatidylcholine bilayers
    • Clarke R.J. Effect of lipid structure on the dipole potential of phosphatidylcholine bilayers. Biochim. Biophys. Acta 1327 (1997) 269-278
    • (1997) Biochim. Biophys. Acta , vol.1327 , pp. 269-278
    • Clarke, R.J.1
  • 15
    • 0034746677 scopus 로고    scopus 로고
    • The dipole potential of phospholipid membranes and methods for its detection
    • Clarke R.J. The dipole potential of phospholipid membranes and methods for its detection. Adv. Colloid Interface Sci. 89-90 (2001) 263-281
    • (2001) Adv. Colloid Interface Sci. , vol.89-90 , pp. 263-281
    • Clarke, R.J.1
  • 16
    • 0031012421 scopus 로고    scopus 로고
    • Optical detection of membrane dipole potential: avoidance of fluidity and dye-induced effects
    • Clarke R.J., and Kane D.J. Optical detection of membrane dipole potential: avoidance of fluidity and dye-induced effects. Biochim. Biophys. Acta 1323 (1997) 223-239
    • (1997) Biochim. Biophys. Acta , vol.1323 , pp. 223-239
    • Clarke, R.J.1    Kane, D.J.2
  • 17
    • 0344171983 scopus 로고    scopus 로고
    • Influence of anions and cations on the dipole potential of phosphatidylcholine vesicles: a basis for the Hofmeister effect
    • Clarke R.J., and Lupfert C. Influence of anions and cations on the dipole potential of phosphatidylcholine vesicles: a basis for the Hofmeister effect. Biophys. J. 76 (1999) 2614-2624
    • (1999) Biophys. J. , vol.76 , pp. 2614-2624
    • Clarke, R.J.1    Lupfert, C.2
  • 18
    • 13844253232 scopus 로고    scopus 로고
    • Electric field strength of membrane lipids from vertebrate species: membrane lipid composition and Na+-K+-ATPase molecular activity
    • Starke-Peterkovic T.N., Turner N., Else P.L., and Clarke R.J. Electric field strength of membrane lipids from vertebrate species: membrane lipid composition and Na+-K+-ATPase molecular activity. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288 (2005) R663-R670
    • (2005) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.288
    • Starke-Peterkovic, T.N.1    Turner, N.2    Else, P.L.3    Clarke, R.J.4
  • 20
    • 0027982642 scopus 로고
    • Dipole potential of lipid membranes
    • Brockman H. Dipole potential of lipid membranes. Chem. Phys. Lipids 73 (1994) 57-79
    • (1994) Chem. Phys. Lipids , vol.73 , pp. 57-79
    • Brockman, H.1
  • 21
    • 36849103950 scopus 로고
    • Analysis of macromolecular polydispersity in intensity correlation spectroscopy: the method of cumulants
    • Koppel D. Analysis of macromolecular polydispersity in intensity correlation spectroscopy: the method of cumulants. J. Chem. Phys. 57 (1972) 4814-4820
    • (1972) J. Chem. Phys. , vol.57 , pp. 4814-4820
    • Koppel, D.1
  • 22
    • 0021327216 scopus 로고
    • Kinetics and thermodynamics of the formation of mixed micelles of egg phosphatidylcholine and bile salts
    • Rajagopalan N., and Lindenbaum S. Kinetics and thermodynamics of the formation of mixed micelles of egg phosphatidylcholine and bile salts. J. Lipid Res. 25 (1984) 135-147
    • (1984) J. Lipid Res. , vol.25 , pp. 135-147
    • Rajagopalan, N.1    Lindenbaum, S.2
  • 23
    • 34047237965 scopus 로고    scopus 로고
    • Solution pH alters mechanical and electrical properties of phosphatidylcholine membranes: relation between interfacial electrostatics, intramembrane potential, and bending elasticity
    • Zhou Y., and Raphael R.M. Solution pH alters mechanical and electrical properties of phosphatidylcholine membranes: relation between interfacial electrostatics, intramembrane potential, and bending elasticity. Biophys. J. 92 (2007) 2451-2462
    • (2007) Biophys. J. , vol.92 , pp. 2451-2462
    • Zhou, Y.1    Raphael, R.M.2
  • 24
    • 0017623677 scopus 로고
    • Liposome-cell interaction: transfer and intracellular release of a trapped fluorescent marker
    • Weinstein J.N., Yoshikami S., Henkart P., Blumenthal R., and Hagins W.A. Liposome-cell interaction: transfer and intracellular release of a trapped fluorescent marker. Science 195 (1977) 489-492
    • (1977) Science , vol.195 , pp. 489-492
    • Weinstein, J.N.1    Yoshikami, S.2    Henkart, P.3    Blumenthal, R.4    Hagins, W.A.5
  • 25
    • 0019329516 scopus 로고
    • Membrane lipid composition and susceptibility to bile salt damage
    • Coleman R., Lowe P.J., and Billington D. Membrane lipid composition and susceptibility to bile salt damage. Biochim. Biophys. Acta 599 (1980) 294-300
    • (1980) Biochim. Biophys. Acta , vol.599 , pp. 294-300
    • Coleman, R.1    Lowe, P.J.2    Billington, D.3
  • 26
    • 0018868656 scopus 로고
    • Effects of bile salts on the plasma membranes of isolated rat hepatocytes
    • Billington D., Evans C.E., Godfrey P.P., and Coleman R. Effects of bile salts on the plasma membranes of isolated rat hepatocytes. Biochem. J. 188 (1980) 321-327
    • (1980) Biochem. J. , vol.188 , pp. 321-327
    • Billington, D.1    Evans, C.E.2    Godfrey, P.P.3    Coleman, R.4
  • 27
    • 0021023912 scopus 로고
    • Studies on the mechanism of bile salt-induced liposomal membrane damage
    • Schubert R., Jaroni H., Schoelmerich J., and Schmidt K.H. Studies on the mechanism of bile salt-induced liposomal membrane damage. Digestion 28 (1983) 181-190
    • (1983) Digestion , vol.28 , pp. 181-190
    • Schubert, R.1    Jaroni, H.2    Schoelmerich, J.3    Schmidt, K.H.4
  • 28
    • 0025025867 scopus 로고
    • Bile acid structure-activity relationship: evaluation of bile acid lipophilicity using 1-octanol/water partition coefficient and reverse phase HPLC
    • Roda A., Minutello A., Angellotti M.A., and Fini A. Bile acid structure-activity relationship: evaluation of bile acid lipophilicity using 1-octanol/water partition coefficient and reverse phase HPLC. J. Lipid Res. 31 (1990) 1433-1443
    • (1990) J. Lipid Res. , vol.31 , pp. 1433-1443
    • Roda, A.1    Minutello, A.2    Angellotti, M.A.3    Fini, A.4
  • 29
    • 0029099276 scopus 로고
    • Bile acid/phosphatidylcholine interactions in mixed monomolecular layers: differences in condensation effects but not interfacial orientation between hydrophobic and hydrophilic bile acid species
    • Fahey D.A., Carey M.C., and Donovan J.M. Bile acid/phosphatidylcholine interactions in mixed monomolecular layers: differences in condensation effects but not interfacial orientation between hydrophobic and hydrophilic bile acid species. Biochemistry 34 (1995) 10886-10897
    • (1995) Biochemistry , vol.34 , pp. 10886-10897
    • Fahey, D.A.1    Carey, M.C.2    Donovan, J.M.3
  • 30
    • 0034719149 scopus 로고    scopus 로고
    • Spread monomolecular films of monohydroxy bile acids and their salts: influence of hydroxyl position, bulk pH, and association with phosphatidylcholine
    • Leonard M.R., Bogle M.A., Carey M.C., and Donovan J.M. Spread monomolecular films of monohydroxy bile acids and their salts: influence of hydroxyl position, bulk pH, and association with phosphatidylcholine. Biochemistry 39 (2000) 16064-16074
    • (2000) Biochemistry , vol.39 , pp. 16064-16074
    • Leonard, M.R.1    Bogle, M.A.2    Carey, M.C.3    Donovan, J.M.4
  • 31
    • 24144501155 scopus 로고    scopus 로고
    • Interfacial properties of most monofluorinated bile acids deviate markedly from the natural congeners: studies with the Langmuir-Pockels surface balance
    • Kauffman J.M., Pellicciari R., and Carey M.C. Interfacial properties of most monofluorinated bile acids deviate markedly from the natural congeners: studies with the Langmuir-Pockels surface balance. J. Lipid Res. 46 (2005) 571-581
    • (2005) J. Lipid Res. , vol.46 , pp. 571-581
    • Kauffman, J.M.1    Pellicciari, R.2    Carey, M.C.3
  • 32
    • 0034903725 scopus 로고    scopus 로고
    • Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia
    • Nishimura Y., and Lemasters J.J. Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia. Cell Death Differ. 8 (2001) 850-858
    • (2001) Cell Death Differ. , vol.8 , pp. 850-858
    • Nishimura, Y.1    Lemasters, J.J.2
  • 33
    • 0034523818 scopus 로고    scopus 로고
    • Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
    • Korsmeyer S.J., Wei M.C., Saito M., Weiler S., Oh K.J., and Schlesinger P.H. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ. 7 (2000) 1166-1173
    • (2000) Cell Death Differ. , vol.7 , pp. 1166-1173
    • Korsmeyer, S.J.1    Wei, M.C.2    Saito, M.3    Weiler, S.4    Oh, K.J.5    Schlesinger, P.H.6
  • 34
    • 24144502833 scopus 로고    scopus 로고
    • Effect of salicylate on the elasticity, bending stiffness, and strength of SOPC membranes
    • Zhou Y., and Raphael R.M. Effect of salicylate on the elasticity, bending stiffness, and strength of SOPC membranes. Biophys. J. 89 (2005) 1789-1801
    • (2005) Biophys. J. , vol.89 , pp. 1789-1801
    • Zhou, Y.1    Raphael, R.M.2
  • 35
    • 0141865601 scopus 로고    scopus 로고
    • Dynamic tension spectroscopy and strength of biomembranes
    • Evans E., Heinrich V., Ludwig F., and Rawicz W. Dynamic tension spectroscopy and strength of biomembranes. Biophys. J. 85 (2003) 2342-2350
    • (2003) Biophys. J. , vol.85 , pp. 2342-2350
    • Evans, E.1    Heinrich, V.2    Ludwig, F.3    Rawicz, W.4
  • 36
    • 0020626591 scopus 로고
    • The influence of bile salt structure on self-association in aqueous solutions
    • Roda A., Hofmann A.F., and Mysels K.J. The influence of bile salt structure on self-association in aqueous solutions. J. Biol. Chem. 258 (1983) 6362-6370
    • (1983) J. Biol. Chem. , vol.258 , pp. 6362-6370
    • Roda, A.1    Hofmann, A.F.2    Mysels, K.J.3
  • 37
    • 0029863204 scopus 로고    scopus 로고
    • Adsorption of mixtures of bile salt taurine conjugates to lecithin-cholesterol membranes: implications for bile salt toxicity and cytoprotection
    • Heuman D.M., Bajaj R.S., and Lin Q. Adsorption of mixtures of bile salt taurine conjugates to lecithin-cholesterol membranes: implications for bile salt toxicity and cytoprotection. J. Lipid Res. 37 (1996) 562-573
    • (1996) J. Lipid Res. , vol.37 , pp. 562-573
    • Heuman, D.M.1    Bajaj, R.S.2    Lin, Q.3


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