-
1
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Köhler G, Milstein C: Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975, 256:495-497.
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Köhler, G.1
Milstein, C.2
-
2
-
-
0020031557
-
Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody
-
Miller RA, Maloney DG, Warnke R, Levy R: Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody. N Engl J Med 1982, 306:517-522.
-
(1982)
N Engl J Med
, vol.306
, pp. 517-522
-
-
Miller, R.A.1
Maloney, D.G.2
Warnke, R.3
Levy, R.4
-
3
-
-
0021680499
-
Effects of monoclonal antibody therapy in patients with chronic lymphocytic leukemia
-
Foon KA, Schroff RW, Bunn PA, et al.: Effects of monoclonal antibody therapy in patients with chronic lymphocytic leukemia. Blood 1984, 64:1085-1093.
-
(1984)
Blood
, vol.64
, pp. 1085-1093
-
-
Foon, K.A.1
Schroff, R.W.2
Bunn, P.A.3
-
5
-
-
33644677932
-
New treatment options have changed the survival of patients with follicular lymphoma
-
Fisher RI, LeBlanc M, Press OW, et al.: New treatment options have changed the survival of patients with follicular lymphoma. J Clin Oncol 2005, 23:8447-8452.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8447-8452
-
-
Fisher, R.I.1
LeBlanc, M.2
Press, O.W.3
-
6
-
-
24644454339
-
Improved survival of follicular lymphoma patients in the United States
-
Swenson WT, Wooldridge JE, Lynch CF, et al.: Improved survival of follicular lymphoma patients in the United States. J Clin Oncol 2005, 23:5019-5026.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5019-5026
-
-
Swenson, W.T.1
Wooldridge, J.E.2
Lynch, C.F.3
-
7
-
-
23044503407
-
Long term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: A study by the Groupe d'Etude des Lymphomes de l'Adulte
-
Feugier P, van Hoof A, Sebban C, et al.: Long term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: A study by the Groupe d'Etude des Lymphomes de l'Adulte. J Clin Oncol 2005, 23:4117-4126.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4117-4126
-
-
Feugier, P.1
van Hoof, A.2
Sebban, C.3
-
8
-
-
33646004738
-
CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: A randomised controlled trial by the MabThera International Trial (MInT) Group
-
Pfreunschuh M, Trumper L, Osterborg A, et al.: CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: A randomised controlled trial by the MabThera International Trial (MInT) Group. Lancet Oncol 2006, 7:379-391.
-
(2006)
Lancet Oncol
, vol.7
, pp. 379-391
-
-
Pfreunschuh, M.1
Trumper, L.2
Osterborg, A.3
-
9
-
-
0345337254
-
Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: Half of patients respond to a four-dose treatment program
-
McLaughlin P, Grillolopez AJ, Link BK, et al.: Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program. J Clin Oncol 1998, 16:2825-2833.
-
(1998)
J Clin Oncol
, vol.16
, pp. 2825-2833
-
-
McLaughlin, P.1
Grillolopez, A.J.2
Link, B.K.3
-
10
-
-
0037108822
-
Rituximab as first-line and maintenance therapy for patients with indolent non-Hodgkin's lymphoma
-
Hainsworth JD, Litchy S, Burris HA, et al.: Rituximab as first-line and maintenance therapy for patients with indolent non-Hodgkin's lymphoma. J Clin Oncol 2002, 20:4261-4267.
-
(2002)
J Clin Oncol
, vol.20
, pp. 4261-4267
-
-
Hainsworth, J.D.1
Litchy, S.2
Burris, H.A.3
-
11
-
-
0033855660
-
Rituximab anti-CD20 monoclonal antibody therapy in non-Hodgkin's lymphoma: Safety and efficacy of re-treatment
-
Davis TA, Grillo-Lopez AJ, White CA, et al.: Rituximab anti-CD20 monoclonal antibody therapy in non-Hodgkin's lymphoma: Safety and efficacy of re-treatment. J Clin Oncol 2000, 18:3135-3143.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3135-3143
-
-
Davis, T.A.1
Grillo-Lopez, A.J.2
White, C.A.3
-
12
-
-
33745878287
-
Unique toxicities and resistance mechanisms associated with monoclonal antibody therapy
-
Friedberg JW: Unique toxicities and resistance mechanisms associated with monoclonal antibody therapy. Hematology Am Soc Hematol Educ Program 2005, 329-334.
-
(2005)
Hematology Am Soc Hematol Educ Program
, pp. 329-334
-
-
Friedberg, J.W.1
-
13
-
-
0642312825
-
Rituximab (monoclonal anti-CD20 antibody): Mechanisms of action and resistance
-
Smith MR: Rituximab (monoclonal anti-MD20 antibody): mechanisms of action and resistance. Oncogene 2003, 22:7359-7368.
-
(2003)
Oncogene
, vol.22
, pp. 7359-7368
-
-
Smith, M.R.1
-
14
-
-
0037452616
-
Variation in gene expression patterns in follicular lymphoma and the response to rituximab
-
Bohen SP, Troyanskaya OG, Alter O, et al.: Variation in gene expression patterns in follicular lymphoma and the response to rituximab. Proc Natl Acad Sci U S A 2003, 100:1926-1930.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1926-1930
-
-
Bohen, S.P.1
Troyanskaya, O.G.2
Alter, O.3
-
15
-
-
33748297773
-
Initial safety and efficacy results of a second-generation humanized anti-CD20 antibody, IMMU-106 (hA20), in non-Hodgkin's lymphoma
-
[abstract 2428]
-
Morschhauser F, Leonard JP, Coiffier B, et al.: Initial safety and efficacy results of a second-generation humanized anti-CD20 antibody, IMMU-106 (hA20), in non-Hodgkin's lymphoma [abstract 2428]. Blood 2005, 106:683a.
-
(2005)
Blood
, vol.106
-
-
Morschhauser, F.1
Leonard, J.P.2
Coiffier, B.3
-
16
-
-
4444343395
-
Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas
-
Teeling JL, French RR, Cragg MS, et al.: Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas. Blood 2004, 104:1793-1800.
-
(2004)
Blood
, vol.104
, pp. 1793-1800
-
-
Teeling, J.L.1
French, R.R.2
Cragg, M.S.3
-
17
-
-
38949185742
-
Safety and efficacy of ofatumumab, a fully human monoclonal anti-CD20 antibody, in patients with relapsed or refractory B-cell chronic lymphocytic leukemia. A phase I-II study
-
Coiffier B, Lepretre S, Pederen LM, et al.: Safety and efficacy of ofatumumab, a fully human monoclonal anti-CD20 antibody, in patients with relapsed or refractory B-cell chronic lymphocytic leukemia. A phase I-II study. Blood 2008, 111:1094-1100.
-
(2008)
Blood
, vol.111
, pp. 1094-1100
-
-
Coiffier, B.1
Lepretre, S.2
Pederen, L.M.3
-
18
-
-
48249127022
-
Interim results of a phase I/II study of ocrelizumab, a new humanized anti-CD20 antibody in patients with relapsed/refractory follicular non-Hodgkin's lymphoma
-
[abstract 645]
-
Morschhauser F, Marlton P, Vitolo U, et al.: Interim results of a phase I/II study of ocrelizumab, a new humanized anti-CD20 antibody in patients with relapsed/refractory follicular non-Hodgkin's lymphoma [abstract 645]. Blood 2007, 110:199a.
-
(2007)
Blood
, vol.110
-
-
Morschhauser, F.1
Marlton, P.2
Vitolo, U.3
-
19
-
-
0035794194
-
High resolution mapping of the binding site on human IgG1 for FcgammaR1, FcgammaRII, FcgammaRIII, and FcRn and design of IgG1 variants with improved binding to the FcR
-
Shields RL, Namenuk AK, Hong K, et al.: High resolution mapping of the binding site on human IgG1 for FcgammaR1, FcgammaRII, FcgammaRIII, and FcRn and design of IgG1 variants with improved binding to the FcR. J Biol Chem 2001, 276:6591-6604.
-
(2001)
J Biol Chem
, vol.276
, pp. 6591-6604
-
-
Shields, R.L.1
Namenuk, A.K.2
Hong, K.3
-
20
-
-
0034655265
-
Mapping of the C1q binding site on Rituxan, a chimeric antibody with human IgG1 Fc
-
Idusogie EE, Presta LG, Gazzano-Santoro H, et al.: Mapping of the C1q binding site on Rituxan, a chimeric antibody with human IgG1 Fc. J Immunol 2000, 164:4178-4184.
-
(2000)
J Immunol
, vol.164
, pp. 4178-4184
-
-
Idusogie, E.E.1
Presta, L.G.2
Gazzano-Santoro, H.3
-
21
-
-
0032147065
-
CD22 negatively and positively regulates signal transduction through the B lymphocyte antigen receptor
-
Sato S, Tuscano JM, Inaoki M, et al.: CD22 negatively and positively regulates signal transduction through the B lymphocyte antigen receptor. Semin Immunol 1998, 10:287-297.
-
(1998)
Semin Immunol
, vol.10
, pp. 287-297
-
-
Sato, S.1
Tuscano, J.M.2
Inaoki, M.3
-
22
-
-
53749095799
-
Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus
-
Dörner T, Kaufmann J, Wegener WA, et al.: Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus. Arthritis Res Ther 2006, 8:R4.
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Dörner, T.1
Kaufmann, J.2
Wegener, W.A.3
-
23
-
-
0042413843
-
Phase I/II trial of epratuzumab (humanized anti-CD22 antibody) in indolent non-Hodgkin's lymphoma
-
Leonard JP, Coleman M, Ketas JC, et al.: Phase I/II trial of epratuzumab (humanized anti-CD22 antibody) in indolent non-Hodgkin's lymphoma. J Clin Oncol 2003, 21:3051-3059.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3051-3059
-
-
Leonard, J.P.1
Coleman, M.2
Ketas, J.C.3
-
24
-
-
4143123338
-
Epratuzumab, a humanized anti-CD22 antibody, in aggressive non-Hodgkin's lymphoma: Phase I/II clinical trial results
-
Leonard JP, Coleman M, Ketas JC, et al.: Epratuzumab, a humanized anti-CD22 antibody, in aggressive non-Hodgkin's lymphoma: Phase I/II clinical trial results. Clin Cancer Res 2004, 10:5327-5334.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5327-5334
-
-
Leonard, J.P.1
Coleman, M.2
Ketas, J.C.3
-
25
-
-
24644476583
-
Combination anti-body therapy with epratuzumab and rituximab in relapsed or refractory non-Hodgkin's lymphoma
-
Leonard JP, Coleman M, Ketas J, et al.: Combination anti-body therapy with epratuzumab and rituximab in relapsed or refractory non-Hodgkin's lymphoma. J Clin Oncol 2005, 23:5044-5051.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5044-5051
-
-
Leonard, J.P.1
Coleman, M.2
Ketas, J.3
-
26
-
-
1942502328
-
Characterization of a new humanized anti-CD20 monoclonal antibody, IMMU-106, and its use in combination with the humanized anti-CD22 antibody, epratuzumab, for the therapy of non-Hodgkin's lymphoma
-
Stein R, Qu Zhengzing, Chen S, et al.: Characterization of a new humanized anti-CD20 monoclonal antibody, IMMU-106, and its use in combination with the humanized anti-CD22 antibody, epratuzumab, for the therapy of non-Hodgkin's lymphoma. Clin Cancer Res 2004, 10:2868-2878.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2868-2878
-
-
Stein, R.1
Qu Zhengzing Chen, S.2
-
27
-
-
31544455876
-
Antitumor efficacy of a combination of CMC-544 (inotuzumab ozogamicin), a CD22-targeted cytotoxic immunoconjugate of calicheamicin, and rituximab against non-Hodgkin's B-cell lymphoma
-
DiJoseph JF, Dougher MM, Kalyandrug LB, et al.: Antitumor efficacy of a combination of CMC-544 (inotuzumab ozogamicin), a CD22-targeted cytotoxic immunoconjugate of calicheamicin, and rituximab against non-Hodgkin's B-cell lymphoma. Clin Cancer Res 2006, 12:242-249.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 242-249
-
-
DiJoseph, J.F.1
Dougher, M.M.2
Kalyandrug, L.B.3
-
28
-
-
0141568082
-
Final results of a phase I radioimmunotherapy trial using 186Re-epratuzumab for the treatment of patients with non-Hodgkin's lymphoma
-
Postema EJ, Raemaekers JM, Oyen WJ, et al.: Final results of a phase I radioimmunotherapy trial using 186Re-epratuzumab for the treatment of patients with non-Hodgkin's lymphoma. Clin Cancer Res 2003, 9:3995S-4002S.
-
(2003)
Clin Cancer Res
, vol.9
-
-
Postema, E.J.1
Raemaekers, J.M.2
Oyen, W.J.3
-
29
-
-
24944581157
-
Preclinical antilymphoma activity of a humanized anti-CD40 monoclonal antibody, SGN-40
-
Law CL, Gordon KA, Collier J, et al.: Preclinical antilymphoma activity of a humanized anti-CD40 monoclonal antibody, SGN-40. Cancer Res 2005, 65:8331-8338.
-
(2005)
Cancer Res
, vol.65
, pp. 8331-8338
-
-
Law, C.L.1
Gordon, K.A.2
Collier, J.3
-
30
-
-
33947285898
-
A phase I study of humanized anti-CD40 immunotherapy with SGN-40 in non-Hodgkin's lymphoma
-
[abstract 1504]
-
Advani RH, Furman RR, Rosenblatt JD, et al.: A phase I study of humanized anti-CD40 immunotherapy with SGN-40 in non-Hodgkin's lymphoma [abstract 1504]. Blood 2005, 106:433a.
-
(2005)
Blood
, vol.106
-
-
Advani, R.H.1
Furman, R.R.2
Rosenblatt, J.D.3
-
31
-
-
34547486091
-
SGN-40 (anti-huCD40 mAb) monotherapy induces durable objective responses in patients with relapsed aggressive non-Hodgkin's lymphoma: Evidence of antitumor activity from a phase I study
-
[abstract 695]
-
Advani R, Forero-Torres A, Furman RR, et al.: SGN-40 (anti-huCD40 mAb) monotherapy induces durable objective responses in patients with relapsed aggressive non-Hodgkin's lymphoma: Evidence of antitumor activity from a phase I study [abstract 695]. Blood 2006, 108:209a.
-
(2006)
Blood
, vol.108
-
-
Advani, R.1
Forero-Torres, A.2
Furman, R.R.3
-
32
-
-
0037092951
-
Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: Results of a large international study
-
Keating MJ, Flinn I, Jain V, et al.: Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: Results of a large international study. Blood 2002, 99:3554-3561.
-
(2002)
Blood
, vol.99
, pp. 3554-3561
-
-
Keating, M.J.1
Flinn, I.2
Jain, V.3
-
33
-
-
37649004407
-
Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia
-
Hillmen P, Skotnicki AB, Robak T, et al.: Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia. J Clin Oncol 2007, 25:5616-5623.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5616-5623
-
-
Hillmen, P.1
Skotnicki, A.B.2
Robak, T.3
-
34
-
-
33947246465
-
Monoclonal antibodies in the treatment of non-Hodgkin's lymphoma
-
Fanale MA, Younes A: Monoclonal antibodies in the treatment of non-Hodgkin's lymphoma. Drugs 2007, 67:333-350.
-
(2007)
Drugs
, vol.67
, pp. 333-350
-
-
Fanale, M.A.1
Younes, A.2
-
35
-
-
22344436992
-
Phase I/II study of galiximab, an anti-CD80 antibody, for relapsed or refractory follicular lymphoma
-
Czuczman MS, Thall A, Witzig TE, et al.: Phase I/II study of galiximab, an anti-CD80 antibody, for relapsed or refractory follicular lymphoma. J Clin Oncol 2005, 23:4390-4398.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4390-4398
-
-
Czuczman, M.S.1
Thall, A.2
Witzig, T.E.3
-
36
-
-
34547844167
-
A phase I/II study of galiximab (an anti-CD80 monoclonal antibody) in combination with rituximab for relapsed or refractory, follicular lymphoma
-
Leonard JP, Friedberg JW, Younes A, et al.: A phase I/II study of galiximab (an anti-CD80 monoclonal antibody) in combination with rituximab for relapsed or refractory, follicular lymphoma. Ann Oncol 2007, 18:1216-1223.
-
(2007)
Ann Oncol
, vol.18
, pp. 1216-1223
-
-
Leonard, J.P.1
Friedberg, J.W.2
Younes, A.3
-
37
-
-
4143052495
-
Developing new monoclonal antibodies for aggressive lymphoma: A challenging road in the rituximab era
-
Friedberg JW: Developing new monoclonal antibodies for aggressive lymphoma: A challenging road in the rituximab era. Clin Cancer Res 2004, 10:5297-5298.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5297-5298
-
-
Friedberg, J.W.1
|