Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models

PLoS ONE

Volumn 4, Issue 1, 2009, Pages

  Tamura, Takuya ^a   Sone, Masaki ^a   Yamashita, Mayumi ^a   Wanker, Erich E ^b   Okazawa, Hitoshi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 1; HUNTINGTIN; TRANSCRIPTION FACTOR GAL4; ATAXIN-1; HD PROTEIN, HUMAN; NERVE PROTEIN; NUCLEAR PROTEIN; PEPTIDE; POLYGLUTAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ATROPHY; BRAIN DEGENERATION; BRAIN SIZE; CELL DIFFERENTIATION; CELL LINEAGE; CEPHALOMETRY; CONTROLLED STUDY; DROSOPHILA; FEMALE; GENE EXPRESSION; GLIA CELL; INSECT DEVELOPMENT; LOCOMOTION; MALE; MUTANT; NERVE CELL DEGENERATION; NEUROBLAST; NONHUMAN; PUPA (LIFE CYCLE STAGE); SURVIVAL; ANIMAL; CROSS BREEDING; CYTOLOGY; DEGENERATIVE DISEASE; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENETICS; GLIA; HUMAN; METABOLISM; MUTATION; NERVE CELL; PATHOLOGY;

ANIMALS; CELL LINEAGE; CROSSES, GENETIC; DROSOPHILA MELANOGASTER; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MALE; MUTATION; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; NEUROGLIA; NEURONS; NUCLEAR PROTEINS; PEPTIDES;

EID: 59249101029     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004262     Document Type: Article

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