Discovery of the hepatitis C virus

Liver International

Volumn 29, Issue SUPPL. 1, 2009, Pages 82-88

  Houghton, Michael ^a  

^a Epiphany Biosciences Inc   (United States)

Author keywords

Characterization; Discovery; HCV; Hepatitis C Virus; Isolation

Indexed keywords

ALANINE AMINOTRANSFERASE; COMPLEMENTARY DNA; HEPATITIS C ANTIBODY; IODINE 125; SINGLE STRANDED RNA; VIRUS RNA;

ANALYTIC METHOD; BLOOD ANALYSIS; BLOOD SAMPLING; BLOOD SCREENING TEST; BLOOD TRANSFUSION; CAUSAL ATTRIBUTION; CHIMPANZEE; CONFERENCE PAPER; DNA HYBRIDIZATION; DNA LIBRARY; GENE EXPRESSION; HEPATITIS C VIRUS; HEPATITIS DELTA VIRUS; HUMAN; IMMUNODETECTION; INFECTION PREVENTION; INTERMETHOD COMPARISON; LIVER; MOLECULAR CLONING; NONHUMAN; RADIOACTIVITY; REVERSE TRANSCRIPTION; VIRUS IDENTIFICATION; VIRUS ISOLATION; VIRUS TITRATION; VIRUS TRANSMISSION;

DNA, COMPLEMENTARY; GENE LIBRARY; HEPACIVIRUS; HISTORY, 20TH CENTURY; VIROLOGY;

EID: 59149104920     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2008.01925.x     Document Type: Conference Paper

References (45)

1. Feinstone SM, Kapikian AZ, Purcell RH, Alter HJ, Holland PV. Transfusion-associated hepatitis not due to viral hepatitis type A or B. N Engl J Med 1975; 292: 767-70.
2. Alter HJ, Holland PV, Morrow AG, et al. Clinical and serological analysis of transfusion-associated hepatitis. Lancet 1975; 2: 838-41.
3. Berman M, Alter HJ, Ishak KG, Purcell RH, Jones EA. The chronic sequelae of non-A, non-B hepatitis. Ann Intern Med 1979; 91: 1-6.
4. Aach RD, Szmuness W, Mosley JW, et al. Serum alanine aminotransferase of donors in relation to the risk of non-A, non-B hepatitis in recipients: the transfusion-transmitted viruses study. N Engl J Med 1981; 304: 989-94.
5. Hoofnagle JH, Alter HJ. Chronic non-A, non-B hepatitis. Prog Clin Biol Res 1985; 182: 63-9.
6. Alter MJ, Gerety RJ, Smallwood LA, et al. Sporadic non-A, non-B hepatitis: Frequency and epidemiology in an urban U.S. population. J Infect Dis 1982; 145: 886-93.
7. Alter HJ, Purcell RH, Holland PV, Popper H. Transmissible agent in non-A, non-B hepatitis. Lancet 1978; 1: 459-63.
8. Tabor E, Gerety RJ, Drucker JA, et al. Transmission of non-A, non-B hepatitis from man to chimpanzee. Lancet 1978; 1: 463-6.
9. Hollinger FB, Gitnick GL, Aach RD, et al. Non-A, non-B hepatitis transmission in chimpanzees: A project of the transfusion-transmitted viruses study group. Intervirology 1978; 10: 60-8.
10. Shimizu YK, Feinstone SM, Purcell RH, Alter HJ, London WT. Non-A, non-B hepatitis: Ultrastructural evidence for two agents in experimentally infected chimpanzees. Science 1979; 205: 197-200.
11. Hollinger FB, Mosley JW, Szmuness W, et al. Transfusion-transmitted viruses study: Experimental evidence for two non-A, non-B, hepatitis agents. J Infect Dis 1980; 142: 400-7.
12. Trépo C, Vitvitski L, Hantz O. Non-A, Non-B hepatitis virus: identification of a core antigen-antibody system that cross reacts with hepatitis B core antigen and antibody. J Med Virol 1981; 8: 31-47.
13. Feinstone SM, Mihalik KB, Kamimura T, et al. Inactivation of hepatitis B virus and non-A, non-B hepatitis by chloroform. Infect Immun 1983; 41: 816-21.
14. Bradley DW, Maynard JE, Popper H, et al. Posttransfusion non-A, non-B hepatitis: Physicochemical properties of two distinct agents. J Infect Dis 1983; 148: 254-65.
15. Bradley DW, McCaustland KA, Cook EH, et al. Posttransfusion non-A, non-B hepatitis in chimpanzees. Physicochemical evidence that the tubule-forming agent is a small, enveloped virus. Gastroenterology 1985; 88: 773-9.
16. Shih JW, Mur JI, Alter HJ. Non-A, non-B hepatitis: Advances and unfulfilled expectations of the first decade. Prog Liver Dis 1986; 8: 433-52.
17. Mullis KB, Faloona FA. Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol 1987; 155: 335-50.
18. Rizzetto M, Canese MG, Aricò S, et al. Immunofluorescence detection of new antigen-antibody system (delta/anti-delta) associated to hepatitis B virus in liver and in serum of HBsAg carriers. Gut 1977; 18: 997-1003.
19. Rizzetto M, Hoyer B, Canese MG, et al. delta Agent: Association of delta antigen with hepatitis B surface antigen and RNA in serum of delta-infected chimpanzees. Proc Natl Acad Sci USA 1980; 77: 6124-8.
20. Kamimura T, Ponzetto A, Bonino F, et al. Cytoplasmic tubular structures in liver of HBsAg carrier chimpanzees infected with delta agent and comparison with cytoplasmic structures in non-A, non-B hepatitis. Hepatology 1983; 3: 631-7.
21. Denniston KJ, Hoyer BH, Smedile A, et al. Cloned fragment of the hepatitis delta virus RNA genome: Sequence and diagnostic application. Science 1986; 232: 873-5.
22. Wang KS, Choo QL, Weiner AJ, et al. Structure, sequence and expression of the hepatitis delta (delta) viral genome. Nature 1986; 323: 508-14. Erratum in: Nature 30 July 1987 to 5 August; 328 (6129): 456.
23. Weiner AJ, Choo QL, Wang KS, et al. A single antigenomic open reading frame of the hepatitis delta virus encodes the epitope(s) of both hepatitis delta antigen polypeptides p24 delta and p27 delta. J Virol 1988; 62: 594-9.
24. Weiner AJ, Wang KS, Choo QL, et al. Hepatitis delta (delta) cDNA clones: undetectable hybridization to nucleic acids from infectious non-A, non-B hepatitis materials and hepatitis B DNA. J Med Virol 1987; 21: 239-47.
25. Feinstone SM, Alter HJ, Dienes HP, et al. Non-A, non-B hepatitis in chimpanzees and marmosets. J Infect Dis 1981; 144: 588-98.
26. Seto B, Coleman Jr WG, Iwarson S, Gerety RJ. Detection of reverse transcriptase activity in association with the non-A, non-B hepatitis agent(s). Lancet 1984; 2: 941-3.
27. Wakita T, Pietschmann T, Kato T, et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med 2005; 11: 791-6. Epub 12 June 2005. Erratum in: Nat Med. 11 August 2005; 11 (8): 905.
28. Shimizu YK, Oomura M, Abe K, et al. Production of antibody associated with non-A, non-B hepatitis in a chimpanzee lymphoblastoid cell line established by in vitro transformation with Epstein-Barr virus. Proc Natl Acad Sci USA 1985; 82: 2138-42.
29. Honda Y, Kondo J, Maeda T, et al. Isolation and purification of a non-A, non-B hepatitis-associated microtubular aggregates protein. J Gen Virol 1990; 71 (Part 9): 1999-2004.
30. Young RA, Davis RW. Efficient isolation of genes by using antibody probes. Proc Natl Acad Sci USA 1983; 80: 1194-8.
31. Bradley DW, Maynard JE. Etiology and natural history of post-transfusion and enterically-transmitted non-A, non-B hepatitis. Semin Liver Dis 1986; 6: 56-66.
32. Choo QL, Kuo G, Weiner AJ, et al. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989; 244: 359-62.
33. Kuo G, Choo QL, Alter HJ, et al. An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 1989; 244: 362-4.
34. Colombo M, Kuo G, Choo QL, et al. Prevalence of antibodies to hepatitis C virus in Italian patients with hepatocellular carcinoma. Lancet 1989; 2: 1006-8.
35. CraxìA, Laffi G, Zignego AL. Hepatitis C virus (HCV) infection: A systemic disease. Mol Aspects Med 2008; 29: 85-95 (review), Epub 21 November 2007.
36. Diepolder HM, Zachoval R, Hoffmann RM, et al. Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection. Lancet 1995; 346: 1006-7.
37. Dodd RY. Current safety of the blood supply in the United States. Int J Hematol 2004; 80: 301-5 (review).
38. Choo QL, Richman KH, Han JH, et al. Genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci USA 1991; 88: 2451-5.
39. Kolykhalov AA, Agapov EV, Blight KJ, et al. Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA. Science 1997; 277: 570-4.
40. Lohmann V, Körner F, Koch J, et al. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 1999; 285: 110-3.
41. Tellinghuisen TL, Evans MJ, von Hahn T, You S, Rice CM. Studying hepatitis C virus: Making the best of a bad virus. J Virol 2007; 81: 8853-67 (r eview), Epub 23 May 2007.
42. Appel N, Schaller T, Penin F, Bartenschlager R. From structure to function: New insights into hepatitis C virus RNA replication. J Biol Chem 2006; 281: 9833-6 (review), Epub 30 December 2005.
43. Watashi K, Shimotohno K. Chemical genetics approach to hepatitis C virus replication: Cyclophilin as a target for anti-hepatitis C virus strategy. Rev Med Virol 2007; 17: 245-52 (review).
44. Choo QL, Kuo G, Ralston R, et al. Vaccination of chimpanzees against infection by the hepatitis C virus. Proc Natl Acad Sci USA 1994; 91: 1294-8.
45. Houghton M, Abrignani S. Prospects for a vaccine against the hepatitis C virus. Nature 2005; 436: 961-6 (review).