Epithelioid trophoblastic tumor: Comparative genomic hybridization and diagnostic DNA genotyping

Modern Pathology

Volumn 22, Issue 2, 2009, Pages 232-238

  Xu, Mina L ^a   Yang, Bin ^b   Carcangiu, Maria Luisa ^c   Hui, Pei ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Comparative genomic hybridization; DNA genotyping; Epithelioid trophoblastic tumor

Indexed keywords

GENOMIC DNA; PARAFFIN;

ADULT; ALLELE; ANATOMICAL VARIATION; ARTICLE; CANCER TISSUE; CHROMOSOME ABERRATION; CHROMOSOME PAIRING; CLINICAL ARTICLE; CLINICAL FEATURE; COMPARATIVE GENOMIC HYBRIDIZATION; DIAGNOSTIC PROCEDURE; DNA EXTRACTION; ENDOMETRIUM TUMOR; EPITHELIOID TROPHOBLASTIC TUMOR; FEMALE; GENE AMPLIFICATION; GENETIC ANALYSIS; GENOME; GENOTYPE; HUMAN; LUNG TUMOR; METAPHASE CHROMOSOME; MOLECULAR MIMICRY; PATERNITY; PRIORITY JOURNAL; TROPHOBLASTIC TUMOR; TUMOR LOCALIZATION; UTERINE CERVIX; UTERUS SARCOMA;

ADULT; CARCINOMA, SQUAMOUS CELL; COMPARATIVE GENOMIC HYBRIDIZATION; DIAGNOSIS, DIFFERENTIAL; ENDOMETRIAL NEOPLASMS; EPITHELIOID CELLS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC SCREENING; GENOTYPE; GESTATIONAL TROPHOBLASTIC NEOPLASMS; HUMANS; ITALY; LUNG NEOPLASMS; MIDDLE AGED; PREGNANCY; UNITED STATES; UTERINE CERVICAL NEOPLASMS;

EID: 59149098550     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2008.165     Document Type: Article

References (13)

1. Shih IM, Kurman RJ. Epithelioid trophoblastic tumor: a neoplasm distinct from choriocarcinoma and placental site trophoblastic tumor simulating carcinoma. Am J Surg Pathol 1998;22:1393-1403.
2. Genest DR, Berkowitz RS, Fisher RA, et al. Gestational trophoblastic disease. In: Tavassoli FA, Devilee P. (eds). World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. IARC Press: Lyon, 2003, pp 250-254.
3. Fadare O, Parkash V, Carcangiu ML, et al. Epithelioid trophoblastic tumor: clinicopathological features with an emphasis on uterine cervical involvement. Mod Pathol 2006;19:75-82.
4. Oldt III RJ, Kurman RJ, Shih IM. Molecular genetic analysis of placental site trophoblastic tumors and epithelioid trophoblastic tumors confirms their trophoblastic origin. Am J Pathol 2002;161:1033-1037.
5. Hui P, Riba A, Pejovic T, et al. Comparative genomic hybridization study of placental site trophoblastic tumour: a report of four cases. Mod Pathol 2004;17:248-251.
6. Budowle B, Sprecher CJ. Concordance study on population database samples using the PowerPlex 16 kit and AmpFISTR Profiler Plus kit and AmpFistr Cofiler kit. J Forensic Sci 2001;46:637-641.
7. Shih IM, Kurman RJ. The pathology of intermediate trophoblastic tumors and tumor-like lesions. Int J Gynecol Pathol 2001;20:31-47.
8. Ahmed MN, Kim K, Haddad B, et al. Comparative genomic hybridization studies in hydatidiform moles and choriocarcinoma: amplification of 7q21-q31 and loss of 8p12-p21 in choriocarcinoma. Cancer Genet Cytogenet 2000;116:10-15.
9. Xue WC, Guan XY, Ngan HY, et al. Malignant placental site trophoblastic tumor: a cytogenetic study using comparative genomic hybridization and chromosome in situ hybridization. Cancer 2002;94:2288-2294.
10. Kallioniemi OP, Kallioniemi A, Piper J, et al. Optimizing comparative genomic hybridization for analysis of DNA sequence copy. Genes Chromosomes Cancer 1994;10:231-243.
11. Bentx M, Plesch A, Stilgenbauer S, et al. Minimal sizes of deletions detected by comparative genomic hybridization. Genes Chromosomes Cancer 1998;21:172-175.
12. Lage JM, Minamiguchi S, Richardson MS. Gestational trophoblastic diseases: update on new immunohistochemical findings. Curr Diagn Pathol 2003;9:1-10.
13. Bifulco C, Jonhson C, Hao LM, et al. Genotypic analysis of hydatidiform mole: an accurate and practical method of diagnosis. Am J Surg Pathol 2008;32:445-451.