Determination of strychnine and brucine in rat plasma using liquid chromatography electrospray ionization mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 49, Issue 2, 2009, Pages 487-491

  Xu, Yanyan ^a,b   Si, Duanyun ^b   Liu, Changxiao ^b  

^a TIANJIN UNIVERSITY   (China)

^b TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

Author keywords

Brucine; LC ESI MS; Rat plasma; Semen Strychni; Strychnine

Indexed keywords

2 PROPANOL; BRUCINE; DICHLOROMETHANE; HEXANE; PLANT EXTRACT; SEMEN STRYCHNI; STRYCHNINE; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; STRYCHNOS NUX VOMICA; VALIDATION STUDY;

2-PROPANOL; ANIMALS; CALIBRATION; CHROMATOGRAPHY, LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; FORMIC ACIDS; HEXANES; MALE; METHANOL; METHYLENE CHLORIDE; MOLECULAR STRUCTURE; QUALITY CONTROL; RATS; RATS, WISTAR; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRYCHNINE; TIME FACTORS;

EID: 59149088845     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.10.020     Document Type: Article

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