Constant Ocular Infection with Chlamydia trachomatis Predicts Risk of Scarring in Children in Tanzania

Ophthalmology

Volumn 116, Issue 2, 2009, Pages 243-247

  Wolle, Meraf A ^a   Muñoz, Beatriz E ^a   Mkocha, Harran ^b   West, Sheila K ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Kongwa Trachoma Project   (Tanzania)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN;

ARTICLE; BACTERIUM CULTURE; CHILD; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; DISEASE SURVEILLANCE; ENDEMIC DISEASE; EYE INFECTION; FEMALE; FOLLOW UP; HUMAN; INCIDENCE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PREDICTION; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK FACTOR; SCAR FORMATION; SINGLE DRUG DOSE; TANZANIA; TRACHOMA; TREATMENT DURATION;

ANTI-BACTERIAL AGENTS; AZITHROMYCIN; CHILD; CHILD, PRESCHOOL; CHLAMYDIA TRACHOMATIS; CICATRIX; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; INFANT; MALE; RISK FACTORS; TANZANIA; TRACHOMA;

EID: 59149085005     PISSN: 01616420     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ophtha.2008.09.011     Document Type: Article

References (24)

1. Resnikoff S., Pascolini D., Etya'ale D., et al. Global data on visual impairment in the year 2002. Bull World Health Organ 82 (2004) 844-851
2. West S.K. Trachoma: new assault on an ancient disease. Prog Retin Eye Res 23 (2004) 381-401
3. West S.K., Muñoz B., Mkocha H., et al. Progression of active trachoma to scarring in a cohort of Tanzanian children. Ophthalmic Epidemiol 8 (2001) 137-144
4. Bobo L., Muñoz B., Viscidi R., et al. Diagnosis of Chlamydia trachomatis eye infection in Tanzania by polymerase chain reaction/enzyme immunoassay. Lancet 338 (1991) 847-850
5. Bird M., Dawson C.R., Schachter J.S., et al. Does the diagnosis of trachoma adequately identify ocular chlamydial infection in trachoma-endemic areas?. J Infect Dis 187 (2003) 1669-1673
6. West E.S., Muñoz B., Mkocha H., et al. Mass treatment and the effect on the load of Chlamydia trachomatis infection in a trachoma-hyperendemic community. Invest Ophthalmol Vis Sci 46 (2005) 83-87
7. Bailey R.L., Hampton T.J., Hayes L.J., et al. Polymerase chain reaction for the detection of ocular chlamydial infection in trachoma endemic communities. J Infect Dis 170 (1994) 709-712
8. Solomon A.W., Holland M.J., Alexander N.D., et al. Mass treatment with single-dose azithromycin for trachoma. N Engl J Med 351 (2004) 1962-1971
9. Michel C.E., Solomon A.W., Magbanua J.P.V., et al. Field evaluation of a rapid point-of-care assay for targeting antibiotic treatment for trachoma control: a comparative study. Lancet 367 (2006) 1585-1590
10. Solomon A.W., Harding-Esch E., Alexander N.D., et al. Two doses of azithromycin to eliminate trachoma in a Tanzanian community. [letter]. N Engl J Med 358 (2008) 1870-1871
11. West S.K., Munoz B., Mkocha H., et al. Trachoma and ocular Chlamydia trachomatis were not eliminated three years after two rounds of mass treatment in a trachoma hyperendemic village. Invest Ophthalmol Vis Sci 48 (2007) 1492-1497
12. Thylefors B., Dawson C.R., Jones B.R., et al. A simple system for the assessment of trachoma and its complications. Bull World Health Organ 65 (1987) 477-483
13. West S.K., Munoz B., Lynch M., et al. Risk factors for constant, severe trachoma among preschool children in Kongwa, Tanzania. Am J Epidemiol 143 (1996) 73-78
14. Bobo L.D., Novak N., Muñoz B., et al. Severe disease in children with trachoma is associated with persistent Chlamydia trachomatis infection. J Infect Dis 176 (1997) 1524-1530
15. Natividad A., Cooke G., Holland M.J., et al. A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatis infection. BMC Med Genet [serial online] 7 (2006) 40. http://www.biomedcentral.com/1471-2350/7/40 Accessed September 3, 2008
16. Natividad A., Wilson J., Koch O., et al. Risk of trachomatous scarring and trichiasis in Gambians varies with SNP haplotypes at the interferon-gamma and interleukin-10 loci. Genes Immun 6 (2005) 332-340
17. Mozzato-Chamay N., Mahdi O.S., Jallow O., et al. Polymorphisms in candidate genes and risk of scarring trachoma in a Chlamydia trachomatis-endemic population. J Infect Dis 182 (2000) 1545-1548
18. Yang X., HayGlass K.T., and Brunham R.C. Genetically determined differences in IL-10 and IFN-gamma responses correlate with clearance of Chlamydia trachomatis mouse pneumonitis infection. J Immunol 156 (1996) 4338-4344
19. Bobo L., Novak N., Mkocha H., et al. Evidence for a predominant proinflammatory conjunctival cytokine response in individuals with trachoma. Infect Immunol 64 (1996) 3273-3279
20. Border W.A., and Noble N.A. Transforming growth factor beta in tissue fibrosis. N Engl J Med 331 (1994) 1286-1292
21. Peeling R.W., Bailey R.L., Conway D.J., et al. Antibody response to the 60-kDa chlamydial heat shock protein is associated with scarring trachoma. J Infect Dis 177 (1998) 256-259
22. Congdon N., West S., Vitale S., et al. Exposure to children and risk of active trachoma in Tanzanian women. Am J Epidemiol 137 (1993) 366-372
23. Smith A., Munoz B., Hsieh Y.H., et al. OmpA genotypic evidence for persistent ocular Chlamydia trachomatis infection in Tanzanian village women. Ophthalmic Epidemiol 8 (2001) 127-135
24. Atik B., Thanh T.T., Luong V.Q., et al. Impact of annual targeted treatment on infectious trachoma and susceptibility to reinfection. JAMA 296 (2006) 1488-1497