Polymorphisms in candidate genes and risk of scarring trachoma in a Chlamydia trachomatis-endemic population

Journal of Infectious Diseases

Volumn 182, Issue 5, 2000, Pages 1545-1548

  Mozzato Chamay, Nadia ^a   Mahdi, Olaimatu S M ^b   Jallow, Ousman ^b   Mabey, David C W ^a   Bailey, Robin L ^a,b   Conway, David J ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 4; MANNOSE BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CHLAMYDIA TRACHOMATIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDEMIC DISEASE; ETHNIC GROUP; FEMALE; GAMBIA; GENE FREQUENCY; GENETIC TRANSCRIPTION; HOMOZYGOTE; HUMAN; IMMUNOREGULATION; INFECTION RISK; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SCAR FORMATION; SINGLE NUCLEOTIDE POLYMORPHISM; TH2 CELL; TRACHOMA;

ADOLESCENT; ADULT; AGED; CARRIER PROTEINS; CASE-CONTROL STUDIES; CHILD; CHLAMYDIA TRACHOMATIS; COLLECTINS; CYTOKINES; FEMALE; HUMAN; INTERLEUKIN-10; INTERLEUKIN-4; MALE; MIDDLE AGE; POLYMORPHISM (GENETICS); PROMOTER REGIONS (GENETICS); RISK; SUPPORT, NON-U.S. GOV'T; TRACHOMA; TUMOR NECROSIS FACTOR;

EID: 0033794255     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315891     Document Type: Article

References (15)

1. Importance of reinfection in the pathogenesis of trachoma
2. Genetically determined differences in IL-10 and IFN-gamma responses correlate with clearance of Chlamydia trachomatis mouse pneumonitis infection
3. Conjunctival scarring in trachoma is associated with depressed cell-mediated immune responses to chlamydial antigens
4. T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC): Responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring
5. TNF-alpha inactivation of collagen receptors: Implications for fibroblast function and fibrosis
6. Scarring trachoma is associated with polymorphism in the tumor necrosis factor alpha (TNF-alpha) gene promoter and with elevated TNF-alpha levels in tear fluid
7. Human mannose-binding protein inhibits infection of HeLa cells by Chlamydia trachomatis
8. An investigation of polymorphism in the interleukin-10 gene promoter
9. Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy
10. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation
11. HLA class I and II polymorphisms and trachomatous scarring in a Chlamydia trachomatis-endemic population
12. A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
13. High frequencies in African and non-African populations of independent mutations in the mannose binding protein gene
14. Mannose binding protein deficiency is not associated with malaria, hepatitis B carriage nor tuberculosis in Africans
15. Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria