Polyamine sharing between tubulin dimers favours microtubule nucleation and elongation via facilitated diffusion

PLoS Computational Biology

Volumn 5, Issue 1, 2009, Pages

  Mechulam, Alain ^a,b   Chernov, Konstantin G ^a,b,c   Mucher, Elodie ^a,b   Hamon, Loic ^a,b   Curmi, Patrick A ^a,b   Pastré, David ^a,b  

^a UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

^b INSERM   (France)

^c INSTITUTE OF PROTEIN RESEARCH   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CYTOLOGY; DIFFUSION; NUCLEATION;

FACILITATED DIFFUSIONS; HIGH RATE; MICROTUBULE ASSEMBLY; MICROTUBULE DYNAMICS; MICROTUBULE NUCLEATION; MICROTUBULES; MULTIVALENT CATIONS; NUCLEATION SITES; POLYAMINES; TARGET SITES;

ELONGATION;

PUTRESCINE; SPERMIDINE; SPERMINE; TUBULIN; POLYAMINE;

ARTICLE; ATOMIC FORCE MICROSCOPY; CARBOXY TERMINAL SEQUENCE; CELL ELONGATION; DIFFUSION; IN VITRO STUDY; IN VIVO STUDY; MICROTUBULE; MICROTUBULE ASSEMBLY; BINDING SITE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DIMERIZATION; PROTEIN BINDING; PROTEIN CONFORMATION; ULTRASTRUCTURE;

BINDING SITES; COMPUTER SIMULATION; DIFFUSION; DIMERIZATION; MICROTUBULES; MODELS, CHEMICAL; MODELS, MOLECULAR; POLYAMINES; PROTEIN BINDING; PROTEIN CONFORMATION; TUBULIN;

EID: 59049084967     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000255     Document Type: Article

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