Characterization of liver toxicity in F344/N rats and B6C3F1 mice after exposure to a flame retardant containing lower molecular weight polybrominated diphenyl ethers

Experimental and Toxicologic Pathology

Volumn 61, Issue 1, 2009, Pages 1-12

  Dunnick, June K ^a   Nyska, Abraham ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Flame retardant; Liver toxicity; Polybrominated diphenyl ethers

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B; FLAME RETARDANT; POLYBROMINATED DIPHENYL ETHER; POLYBROMINATED DIPHENYL ETHER 100; POLYBROMINATED DIPHENYL ETHER 153; POLYBROMINATED DIPHENYL ETHER 47; POLYBROMINATED DIPHENYL ETHER 99; UNCLASSIFIED DRUG; CYTOCHROME P450; DIPHENYL ETHER DERIVATIVE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL VACUOLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FISCHER 344 RAT; HYPERTROPHY; INCIDENCE; LIVER; LIVER CELL; LIVER TOXICITY; LIVER WEIGHT; MALE; MOLECULAR WEIGHT; MOUSE; MOUSE STRAIN; NONHUMAN; RAT; TARGET ORGAN; THYROID DISEASE; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; LIVER DISEASE; PATHOLOGY; TISSUE DISTRIBUTION; TOXIC HEPATITIS; TOXICITY;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLAME RETARDANTS; HALOGENATED DIPHENYL ETHERS; LIVER; LIVER DISEASES; MALE; MICE; MICE, INBRED C57BL; RATS; RATS, INBRED F344; THYROID DISEASES; TISSUE DISTRIBUTION; DRUG-INDUCED LIVER INJURY;

ANIMALIA; MUS; RATTUS;

EID: 58949102928     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2008.06.008     Document Type: Article

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