-
1
-
-
0028879760
-
Cisplatin and DNA repair in cancer chemotherapy
-
Zamble D.B., and Lippard S.J. Cisplatin and DNA repair in cancer chemotherapy. Trends Biochem Sci 20 (1995) 435-439
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 435-439
-
-
Zamble, D.B.1
Lippard, S.J.2
-
2
-
-
0031748545
-
Glutathione-dependent bioactivation of haloalkenes
-
Anders M.W., and Dekant W. Glutathione-dependent bioactivation of haloalkenes. Annu Rev Pharmacol Toxicol 38 (1998) 501-537
-
(1998)
Annu Rev Pharmacol Toxicol
, vol.38
, pp. 501-537
-
-
Anders, M.W.1
Dekant, W.2
-
3
-
-
0027516023
-
Bioactivation of nephrotoxins and renal carcinogens by glutathione S-conjugate formation
-
Dekant W. Bioactivation of nephrotoxins and renal carcinogens by glutathione S-conjugate formation. Toxicol Lett 67 (1993) 151-160
-
(1993)
Toxicol Lett
, vol.67
, pp. 151-160
-
-
Dekant, W.1
-
4
-
-
0024514780
-
Metabolism of the nephrotoxin dichloroacetylene by glutathione conjugation
-
Kanhai W., Dekant W., and Henschler D. Metabolism of the nephrotoxin dichloroacetylene by glutathione conjugation. Chem Res Toxicol 2 (1989) 51-56
-
(1989)
Chem Res Toxicol
, vol.2
, pp. 51-56
-
-
Kanhai, W.1
Dekant, W.2
Henschler, D.3
-
5
-
-
0023635540
-
Nephrotoxicity of S-(2-chloroethyl)glutathione in the Fischer rat: evidence for gamma-glutamyltranspeptidase-independent uptake by the kidney
-
Kramer R.A., Foureman G., Greene K.E., and Reed D.J. Nephrotoxicity of S-(2-chloroethyl)glutathione in the Fischer rat: evidence for gamma-glutamyltranspeptidase-independent uptake by the kidney. J Pharmacol Exp Ther 242 (1987) 741-748
-
(1987)
J Pharmacol Exp Ther
, vol.242
, pp. 741-748
-
-
Kramer, R.A.1
Foureman, G.2
Greene, K.E.3
Reed, D.J.4
-
6
-
-
0020609675
-
In vivo and in vitro nephrotoxicity of the cysteine conjugate of hexachlorobutadiene
-
Jaffe D.R. In vivo and in vitro nephrotoxicity of the cysteine conjugate of hexachlorobutadiene. J Toxicol Environ Health 11 (1983) 857-863
-
(1983)
J Toxicol Environ Health
, vol.11
, pp. 857-863
-
-
Jaffe, D.R.1
-
7
-
-
0028171462
-
Inhibition of gamma-glutamyl transpeptidase activity by acivicin in vivo protects the kidney from cisplatin-induced toxicity
-
Hanigan M.H., Gallagher B.C., Taylor Jr. P.T., and Large M.K. Inhibition of gamma-glutamyl transpeptidase activity by acivicin in vivo protects the kidney from cisplatin-induced toxicity. Cancer Res 54 (1994) 5925-5929
-
(1994)
Cancer Res
, vol.54
, pp. 5925-5929
-
-
Hanigan, M.H.1
Gallagher, B.C.2
Taylor Jr., P.T.3
Large, M.K.4
-
8
-
-
0035149381
-
Gamma-glutamyl transpeptidase-deficient mice are resistant to the nephrotoxic effects of cisplatin
-
Hanigan M.H., Lykissa E.D., Townsend D.M., Ou C.N., Barrios R., and Lieberman M.W. Gamma-glutamyl transpeptidase-deficient mice are resistant to the nephrotoxic effects of cisplatin. Am J Pathol 159 (2001) 1889-1894
-
(2001)
Am J Pathol
, vol.159
, pp. 1889-1894
-
-
Hanigan, M.H.1
Lykissa, E.D.2
Townsend, D.M.3
Ou, C.N.4
Barrios, R.5
Lieberman, M.W.6
-
9
-
-
0037218695
-
Metabolism of cisplatin to a nephrotoxin in proximal tubule cells
-
Townsend D.M., Deng M., Zhang L., Lapus M.G., and Hanigan M.H. Metabolism of cisplatin to a nephrotoxin in proximal tubule cells. J Am Soc Nephrol 14 (2003) 1-10
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1-10
-
-
Townsend, D.M.1
Deng, M.2
Zhang, L.3
Lapus, M.G.4
Hanigan, M.H.5
-
10
-
-
0036139415
-
Inhibition of gamma-glutamyl transpeptidase or cysteine S-conjugate beta-lyase activity blocks the nephrotoxicity of cisplatin in mice
-
Townsend D.M., and Hanigan M.H. Inhibition of gamma-glutamyl transpeptidase or cysteine S-conjugate beta-lyase activity blocks the nephrotoxicity of cisplatin in mice. J Pharmacol Exp Ther 300 (2002) 142-148
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 142-148
-
-
Townsend, D.M.1
Hanigan, M.H.2
-
11
-
-
0037518294
-
High pressure liquid chromatography and mass spectrometry characterization of the nephrotoxic biotransformation products of cisplatin
-
Townsend D.M., Marto J.A., Deng M., Macdonald T.J., and Hanigan M.H. High pressure liquid chromatography and mass spectrometry characterization of the nephrotoxic biotransformation products of cisplatin. Drug Metab Dispos 31 (2003) 705-713
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 705-713
-
-
Townsend, D.M.1
Marto, J.A.2
Deng, M.3
Macdonald, T.J.4
Hanigan, M.H.5
-
12
-
-
15844416284
-
Coordinated induction of MRP/GS-X pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cells
-
Ishikawa T., Bao J.J., Yamane Y., Akimaru K., Frindrich K., Wright C.D., et al. Coordinated induction of MRP/GS-X pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cells. J Biol Chem 271 (1996) 14981-14988
-
(1996)
J Biol Chem
, vol.271
, pp. 14981-14988
-
-
Ishikawa, T.1
Bao, J.J.2
Yamane, Y.3
Akimaru, K.4
Frindrich, K.5
Wright, C.D.6
-
13
-
-
0025093583
-
Drug resistance to cis-diamminedichloroplatinum (II) in Chinese hamster ovary cell lines transfected with glutathione S-transferase Pi gene
-
Miyazaki M., Kohno K., Saburi Y., Matsuo K., Ono M., Kuwano M., et al. Drug resistance to cis-diamminedichloroplatinum (II) in Chinese hamster ovary cell lines transfected with glutathione S-transferase Pi gene. Biochem Biophys Res Commun 166 (1990) 1358-1364
-
(1990)
Biochem Biophys Res Commun
, vol.166
, pp. 1358-1364
-
-
Miyazaki, M.1
Kohno, K.2
Saburi, Y.3
Matsuo, K.4
Ono, M.5
Kuwano, M.6
-
14
-
-
0023936271
-
Levels of glutathione S-transferase pi mRNA in human lung cancer cell lines correlate with the resistance to cisplatin and carboplatin
-
Nakagawa K., Yokota J., Wada M., Sasaki Y., Fujiwara Y., Sakai M., et al. Levels of glutathione S-transferase pi mRNA in human lung cancer cell lines correlate with the resistance to cisplatin and carboplatin. Jpn J Cancer Res 79 (1988) 301-304
-
(1988)
Jpn J Cancer Res
, vol.79
, pp. 301-304
-
-
Nakagawa, K.1
Yokota, J.2
Wada, M.3
Sasaki, Y.4
Fujiwara, Y.5
Sakai, M.6
-
15
-
-
0142258488
-
Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells
-
Townsend D.M., Shen H., Staros A.L., Gate L., and Tew K.D. Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells. Mol Cancer Ther 1 (2002) 1089-1095
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 1089-1095
-
-
Townsend, D.M.1
Shen, H.2
Staros, A.L.3
Gate, L.4
Tew, K.D.5
-
16
-
-
0032562526
-
Association between expression of glutathione-associated enzymes and response to platinum-based chemotherapy in head and neck cancer
-
Nishimura T., Newkirk K., Sessions R.B., Andrews P.A., Trock B.J., Rusmussen A.A., et al. Association between expression of glutathione-associated enzymes and response to platinum-based chemotherapy in head and neck cancer. Chem Biol Interact 111-112 (1998) 187-198
-
(1998)
Chem Biol Interact
, vol.111-112
, pp. 187-198
-
-
Nishimura, T.1
Newkirk, K.2
Sessions, R.B.3
Andrews, P.A.4
Trock, B.J.5
Rusmussen, A.A.6
-
17
-
-
0029561598
-
The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
-
Hayes J.D., and Pulford D.J. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 30 (1995) 445-600
-
(1995)
Crit Rev Biochem Mol Biol
, vol.30
, pp. 445-600
-
-
Hayes, J.D.1
Pulford, D.J.2
-
18
-
-
0033732323
-
Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi
-
Henderson C.J., Wolf C.R., Kitteringham N., Powell H., Otto D., and Park B.K. Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi. Proc Natl Acad Sci U S A 97 (2000) 12741-12745
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12741-12745
-
-
Henderson, C.J.1
Wolf, C.R.2
Kitteringham, N.3
Powell, H.4
Otto, D.5
Park, B.K.6
-
19
-
-
0032574751
-
Increased skin tumorigenesis in mice lacking Pi class glutathione S-transferases
-
Henderson C.J., Smith A.G., Ure J., Brown K., Bacon E.J., and Wolf C.R. Increased skin tumorigenesis in mice lacking Pi class glutathione S-transferases. Proc Natl Acad Sci U S A 95 (1998) 5275-5280
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5275-5280
-
-
Henderson, C.J.1
Smith, A.G.2
Ure, J.3
Brown, K.4
Bacon, E.J.5
Wolf, C.R.6
-
20
-
-
8644244731
-
Influence of glutathione S-transferase Pi and p53 expression on tumor frequency and spectrum in mice
-
Gate L., Majumdar R.S., Lunk A., and Tew K.D. Influence of glutathione S-transferase Pi and p53 expression on tumor frequency and spectrum in mice. Int J Cancer 113 (2005) 29-35
-
(2005)
Int J Cancer
, vol.113
, pp. 29-35
-
-
Gate, L.1
Majumdar, R.S.2
Lunk, A.3
Tew, K.D.4
-
21
-
-
0028344032
-
Isolation and characterization of two mouse Pi-class glutathione S-transferase genes
-
Bammler T.K., Smith C.A., and Wolf C.R. Isolation and characterization of two mouse Pi-class glutathione S-transferase genes. Biochem J 298 Pt. 2 (1994) 385-390
-
(1994)
Biochem J
, vol.298
, Issue.PART 2
, pp. 385-390
-
-
Bammler, T.K.1
Smith, C.A.2
Wolf, C.R.3
-
23
-
-
0017664570
-
Phase I study of high-dose cis-dichlorodiammineplatinum(II) with forced diuresis
-
Chary K.K., Higby D.J., Henderson E.S., and Swinerton K.D. Phase I study of high-dose cis-dichlorodiammineplatinum(II) with forced diuresis. Cancer Treat Rep 61 (1977) 367-370
-
(1977)
Cancer Treat Rep
, vol.61
, pp. 367-370
-
-
Chary, K.K.1
Higby, D.J.2
Henderson, E.S.3
Swinerton, K.D.4
-
24
-
-
36248941456
-
Constitutive mRNA expression of various glutathione S-transferase isoforms in different tissues of mice
-
Knight T.R., Choudhuri S., and Klaassen C.D. Constitutive mRNA expression of various glutathione S-transferase isoforms in different tissues of mice. Toxicol Sci 100 (2007) 513-524
-
(2007)
Toxicol Sci
, vol.100
, pp. 513-524
-
-
Knight, T.R.1
Choudhuri, S.2
Klaassen, C.D.3
-
25
-
-
38949126520
-
Chemical toxicology of reactive intermediates formed by the glutathione-dependent bioactivation of halogen-containing compounds
-
Anders M.W. Chemical toxicology of reactive intermediates formed by the glutathione-dependent bioactivation of halogen-containing compounds. Chem Res Toxicol 21 (2008) 145-159
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 145-159
-
-
Anders, M.W.1
-
26
-
-
0028190695
-
Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate beta-lyase pathway
-
Anders M.W., and Dekant W. (Eds), Academic Press Inc., New York
-
Dekant W., Vamvakas S., and Anders M.W. Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate beta-lyase pathway. In: Anders M.W., and Dekant W. (Eds). Advances in pharmacology vol. 27 (1994), Academic Press Inc., New York 115-162
-
(1994)
Advances in pharmacology
, vol.27
, pp. 115-162
-
-
Dekant, W.1
Vamvakas, S.2
Anders, M.W.3
-
27
-
-
0021213564
-
Cisplatin metabolites in plasma: a study of their pharmacokinetics and importance in the nephrotoxic and antitumour activity of cisplatin
-
Daley-Yates P.T., and McBrien D.C.H. Cisplatin metabolites in plasma: a study of their pharmacokinetics and importance in the nephrotoxic and antitumour activity of cisplatin. Biochem Pharmacol 33 (1984) 3063-3070
-
(1984)
Biochem Pharmacol
, vol.33
, pp. 3063-3070
-
-
Daley-Yates, P.T.1
McBrien, D.C.H.2
-
28
-
-
0029830842
-
Cisplatin nephrotoxicity: inhibition of gamma-glutamyl transpeptidase blocks the nephrotoxicity of cisplatin without reducing platinum concentrations in the kidney
-
Hanigan M.H., Gallagher B.C., and Taylor Jr. P.T. Cisplatin nephrotoxicity: inhibition of gamma-glutamyl transpeptidase blocks the nephrotoxicity of cisplatin without reducing platinum concentrations in the kidney. Am J Obstet Gynecol 175 (1996) 270-274
-
(1996)
Am J Obstet Gynecol
, vol.175
, pp. 270-274
-
-
Hanigan, M.H.1
Gallagher, B.C.2
Taylor Jr., P.T.3
-
29
-
-
0034978803
-
Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways
-
Ruscoe J.E., Rosario L.A., Wang T., Gate L., Arifoglu P., Wolf C.R., et al. Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways. J Pharmacol Exp Ther 298 (2001) 339-345
-
(2001)
J Pharmacol Exp Ther
, vol.298
, pp. 339-345
-
-
Ruscoe, J.E.1
Rosario, L.A.2
Wang, T.3
Gate, L.4
Arifoglu, P.5
Wolf, C.R.6
-
30
-
-
0036798967
-
Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli
-
Ishimoto T.M., and Ali-Osman F. Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli. Pharmacogenetics 12 (2002) 543-553
-
(2002)
Pharmacogenetics
, vol.12
, pp. 543-553
-
-
Ishimoto, T.M.1
Ali-Osman, F.2
-
31
-
-
0642374221
-
The role of glutathione-S-transferase in anti-cancer drug resistance
-
Townsend D.M., and Tew K.D. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene 22 (2003) 7369-7375
-
(2003)
Oncogene
, vol.22
, pp. 7369-7375
-
-
Townsend, D.M.1
Tew, K.D.2
-
32
-
-
34548067158
-
Genetic polymorphism and function of glutathione S-transferases in tumor drug resistance
-
Lo H.W., and Ali-Osman F. Genetic polymorphism and function of glutathione S-transferases in tumor drug resistance. Curr Opin Pharmacol 7 (2007) 367-374
-
(2007)
Curr Opin Pharmacol
, vol.7
, pp. 367-374
-
-
Lo, H.W.1
Ali-Osman, F.2
-
33
-
-
33646503921
-
Advance in antitumour agents targeting glutathione-S-transferase
-
Zhao G., and Wang X. Advance in antitumour agents targeting glutathione-S-transferase. Curr Med Chem 13 (2006) 1461-1471
-
(2006)
Curr Med Chem
, vol.13
, pp. 1461-1471
-
-
Zhao, G.1
Wang, X.2
-
34
-
-
0023679751
-
Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines
-
Tew K.D., Bomber A.M., and Hoffman S.J. Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines. Cancer Res 48 (1988) 3622-3625
-
(1988)
Cancer Res
, vol.48
, pp. 3622-3625
-
-
Tew, K.D.1
Bomber, A.M.2
Hoffman, S.J.3
-
35
-
-
0026347638
-
Phase I study of thiotepa in combination with the glutathione transferase inhibitor ethacrynic acid
-
O'Dwyer P.J., LaCreta F., Nash S., Tinsley P.W., Schilder R., Clapper M.L., et al. Phase I study of thiotepa in combination with the glutathione transferase inhibitor ethacrynic acid. Cancer Res 51 (1991) 6059-6065
-
(1991)
Cancer Res
, vol.51
, pp. 6059-6065
-
-
O'Dwyer, P.J.1
LaCreta, F.2
Nash, S.3
Tinsley, P.W.4
Schilder, R.5
Clapper, M.L.6
-
36
-
-
0028062141
-
Pharmacokinetics and bioavailability study of ethacrynic acid as a modulator of drug resistance in patients with cancer
-
LaCreta F.P., Brennan J.M., Nash S.L., Comis R.L., Tew K.D., and O'Dwyer P.J. Pharmacokinetics and bioavailability study of ethacrynic acid as a modulator of drug resistance in patients with cancer. J Pharmacol Exp Ther 270 (1994) 1186-1191
-
(1994)
J Pharmacol Exp Ther
, vol.270
, pp. 1186-1191
-
-
LaCreta, F.P.1
Brennan, J.M.2
Nash, S.L.3
Comis, R.L.4
Tew, K.D.5
O'Dwyer, P.J.6
-
37
-
-
34548013285
-
Ethacrynic acid butyl-ester induces apoptosis in leukemia cells through a hydrogen peroxide mediated pathway independent of glutathione S-transferase P1-1 inhibition
-
Wang R., Li C., Song D., Zhao G., Zhao L., and Jing Y. Ethacrynic acid butyl-ester induces apoptosis in leukemia cells through a hydrogen peroxide mediated pathway independent of glutathione S-transferase P1-1 inhibition. Cancer Res 67 (2007) 7856-7864
-
(2007)
Cancer Res
, vol.67
, pp. 7856-7864
-
-
Wang, R.1
Li, C.2
Song, D.3
Zhao, G.4
Zhao, L.5
Jing, Y.6
-
38
-
-
0038345017
-
Cancer drugs, genetic variation and the glutathione-S-transferase gene family
-
Townsend D., and Tew K. Cancer drugs, genetic variation and the glutathione-S-transferase gene family. Am J Pharmacogenomics 3 (2003) 157-172
-
(2003)
Am J Pharmacogenomics
, vol.3
, pp. 157-172
-
-
Townsend, D.1
Tew, K.2
-
39
-
-
0031919247
-
Glutathione conjugation of trichloroethylene in rats and mice:sex-, species-, and tissue-dependent differences
-
Lash L.H., Qian W., Putt D.A., Jacobs K., Elfarra A.A., Krause R.J., and Parker J.C. Glutathione conjugation of trichloroethylene in rats and mice:sex-, species-, and tissue-dependent differences. Drug Metab Dispos 26 (1998) 12-19
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 12-19
-
-
Lash, L.H.1
Qian, W.2
Putt, D.A.3
Jacobs, K.4
Elfarra, A.A.5
Krause, R.J.6
Parker, J.C.7
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