Function-oriented synthesis applied to the anti-botulinum natural product toosendanin

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 3, 2009, Pages 1152-1157

  Nakai, Yuya ^a   Tepp, William H ^b   Dickerson, Tobin J ^a   Johnson, Eric A ^b   Janda, Kim D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

Author keywords

4 Acetoxy CD fragment; Botulinum neurotoxins; Function oriented synthesis (FOS); Toosendanin

Indexed keywords

4 ACETOXY 1,7A EPOXY 3 PHENYL 3A,7,7 TRIMETHYL 1,2,3A,4,7,7A HEXAHYDRO 3H INDEN 5 ONE; ACETIC ACID DERIVATIVE; ACETONE; BOTULINUM TOXIN; NATURAL PRODUCT; TOOSENDANIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHINESE MEDICINE; DRUG SYNTHESIS; MOUSE; NONHUMAN; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; BOTULINUM TOXINS; BOTULISM; CLOSTRIDIUM BOTULINUM; DRUGS, CHINESE HERBAL; LIMONINS; MEDICINE, CHINESE TRADITIONAL; MICE;

ANIMALIA;

EID: 58949093579     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.12.042     Document Type: Article

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