FGF9-induced proliferative response to eosinophilic inflammation in oesophagitis

Gut

Volumn 58, Issue 2, 2009, Pages 166-173

  Mulder, D J ^a,b   Pacheco, I ^b   Hurlbut, D J ^a   Mak, N ^b   Furuta, G T ^c   MacLeod, R J ^a,b   Justinich, C J ^a,b  

^a QUEEN S UNIVERSITY   (Canada)

^b KINGSTON GENERAL HOSPITAL   (Canada)

^c CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BROXURIDINE; CALCIUM; CALCIUM SENSING RECEPTOR; FIBROBLAST GROWTH FACTOR 9; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; MAJOR BASIC PROTEIN; MESSENGER RNA; NOGGIN; PEPTIDE; POLYARGININE; RECEPTOR; RECOMBINANT RECEPTOR; RNA DIRECTED DNA POLYMERASE; SMALL INTERFERING RNA; TETRAZOLIUM;

ARTICLE; CELL HYPERPLASIA; CELL PROLIFERATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; EOSINOPHILIC ESOPHAGITIS; EPITHELIUM CELL; ESOPHAGITIS; ESOPHAGUS BIOPSY; ESOPHAGUS MUCOSA; FIBROBLAST; GASTROESOPHAGEAL REFLUX; HUMAN; HUMAN CELL; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INJURY; MEDIATOR; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

ADOLESCENT; BONE MORPHOGENETIC PROTEINS; CALCIUM; CELL LINE, TUMOR; CELL PROLIFERATION; CHILD; CHILD, PRESCHOOL; EOSINOPHIL MAJOR BASIC PROTEIN; EOSINOPHILIA; EPITHELIAL CELLS; ESOPHAGITIS; ESOPHAGUS; FEMALE; FIBROBLAST GROWTH FACTOR 9; HUMANS; MALE; PEPTIDES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; RECEPTORS, CALCIUM-SENSING; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC;

EID: 58849153685     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gut.2008.157628     Document Type: Article

References (31)

1. . Furuta GT, Liacouras CA, Collins MH, et al. Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. Gastroenterology 2007;133:1342-63.
2. Gleich GJ. Mechanisms of eosinophil-associated inflammation. J Allergy Clin Immunol 2000;105:651-63.
3. Mueller S, Aigner T, Neureiter D, et al. Eosinophil infiltration and degranulation in oesophageal mucosa from adult patients with eosinophilic oesophagitis: a retrospective and comparative study on pathological biopsy. J Clin Pathol 2006;59:1175-80.
4. Ackerman SJ, Loegering DA, Venge P, et al. Distinctive cationic proteins of the human eosinophil granule: major basic protein, eosinophil cationic protein, and eosinophil-derived neurotoxin. J Immunol 1983;131:2977-82.
5. Pegorier S, Wagner LA, Gleich GJ, et al. Eosinophil-derived cationic proteins activate the synthesis of remodeling factors by airway epithelial cells. J Immunol 2006;177:4861-9.
6. Furuta GT, Nieuwenhuis EE, Karhausen J, et al. Eosinophils alter colonic epithelial barrier function: role for major basic protein. Am J Physiol Gastrointest Liver Physiol 2005;289:G890-7.
7. Kim KC, Gleich GJ, Lee MK. Two eosinophil granule proteins, eosinophil peroxidase and major basic protein, inhibit mucin release from hamster tracheal surface epithelial cells in primary culture. Inflamm Res 1999;48:314-7.
8. Mishra A, Wang M, Pemmaraju VR, et al. Esophageal remodeling develops as a consequence of tissue specific IL-5-induced eosinophilia. Gastroenterology 2008;134:204-14.
9. Furuta GT, Ackerman SJ, Varga J, et al. Eosinophil granule-derived major basic protein induces IL-8 expression in human intestinal myofibroblasts. Clin Exp Immunol 2000;122:35-40.
10. Brown EM, Katz C, Butters R, et al. Polyarginine, polylysine, and protamine mimic the etfects of high extracellular calcium concentrations on dispersed bovine parathyroid cells. J Bone Miner Res 1991;6:1217-25.
11. Brown EM, MacLeod RJ. Extracellular calcium sensing and extracellular calcium signaling. Physiol Rev 2001;81:239-7.
12. Justinich CJ, Mak N, Pacheco I, et al. The extracellular calcium-sensing receptor (CaSR) on human esophagus and evidence of expression of the CaSR on the esophageal epithelial cell line (HET-1A). Am J Physiol Gastrointest Liver Physiol 2007;294:G120-9.
13. Thomas LL, Kubo H, Loegering DJ, et al. Peptide-based analysis of amino acid sequences important to the biological activity of eosinophil granule major basic protein. Immunol Lett 2001;78:175- 81.
14. Garcia BH 2nd, Hargrave A, Morgan A, et al. Antibody microarray analysis of inflammatory mediator release by human leukemia T-cells and human non small cell lung cancer cells. J Biomol Tech 2007;18:245-51.
15. Komi-Kuramochi A, Kawano M, Oda Y, et al. Expression of fibroblast growth factors and their receptors during full-thickness skin wound healing in young and aged mice. J Endocrinol 2005;186:273-89.
16. Antoine M, Wirz W, Tag CG, et al. Expression and function of fibroblast growth factor (FGF) 9 in hepatic stellate cells and its role in toxic liver injury. Biochem Biophys Res Commun 2007;361:335-41.
17. Zhang X, Ibrahimi OA, Olsen SK, et al. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem 2006;281:15694-700.
18. Eswarakumar VP, Lax I, Schlessinger J. Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev 2005;16:139-49.
19. Zhang X, Stappenbeck TS, White AC, et al. Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development. Development 2006;133:173-80.
20. Ishizuya-Oka A, Hasebe T. Sonic hedgehog and bone morphogenetic protein-4 signaling pathway involved in epithelial cell renewal along the radial axis of the intestine. Digestion 2008;77(Suppl 1):42-7.
21. Peiris D, Pacheco I, Spencer C, et al. The extracellular calcium-sensing receptor reciprocally regulates the secretion of BMP-2 and the BMP antagonist Noggin in colonic myofibroblasts. Am J Physiol Gastrointest Liver Physiol 2007;292:G753-66.
22. Hardwick JC, Van Den Brink GR, Bleuming SA, et al. Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon. Gastroenterology 2004;126:111-21.
23. Stoner GD, Kaighn ME, Reddel RR, et al. Establishment and characterization of SV40 T-antigen immortalized human esophageal epithelial cells. Cancer Res 1991;51:365-71.
24. Steiner SJ, Kernek KM, Fitzgerald JF. Severity of basal cell hyperplasia differs in reflux versus eosinophilic esophagitis. J Pediatr Gastroenterol Nutr 2006;42:506-9.
25. MacLeod RJ, Hayes M, Pacheco I. Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells. Am J Physiol Gastrointest Liver Physiol 2007;293:G403-11.
26. Ward DT, Maldonado-Perez D, Hollins L, et al. Aminoglycosides induce acute cell signaling and chronic cell death in renal cells that express the calcium-sensing receptor. J Am Soc Nephrol 2005;16:1236-44.
27. 2+-sensing receptor. Am J Physiol Cell Physiol 2002;282:C1414-22.
28. Reinholz MM, Iturria SJ, Ingle JN, et al. Differential gene expression of TGF-beta family members and osteopontin in breast tumor tissue: analysis by real-time quantitative PCR. Breast Cancer Res Treat 2002;74:255-69.
29. Agrotis A, Kanellakis P, Kostolias G, et al. Proliferation of neointimal smooth muscle cells after arterial injury. Dependence on interactions between fibroblast growth factor receptor-2 and fibroblast growth factor-9. J Biol Chem 2004;279:42221-9.
30. Martinon F, Rabian C, Loiseau P, et al. In vitro proliferation of human lymphocytes measured by an enzyme immunoassay using an anti-5-bromo-2-deoxyuridine monoclonal antibody. J Clin Lab Immunol 1987;23:153-9.
31. Mikami Y, Sakamoto T, Yazawa K, et al. Comparison of in vitro antifungal activity of itraconazole and hydroxy-itraconazole by colorimetric MTT assay. Mycoses 1994;37:27-33.