Pathomechanisms of cyst formation in pulmonary light chain deposition disease

European Respiratory Journal

Volumn 32, Issue 5, 2008, Pages 1399-1403

  Colombat, M ^a   Caudroy, S ^d,e   Lagonotte, E ^e   Mal, H ^b   Danel, C ^c   Stern, M ^f   Fournier, M ^b   Birembaut, P ^d,e  

^a HÔPITAL TENON   (France)

^b BICHAT HOSPITAL   (France)

^c HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^d INSERM   (France)

^e HÔPITAL MAISON BLANCHE   (France)

^f FOCH HOSPITAL   (France)

Author keywords

Cyst; Elastic fibre; Light chain deposition disease; Lung; Matrix metalloproteinases

Indexed keywords

COLLAGEN; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14;

ADULT; ARTICLE; BASEMENT MEMBRANE; CELL LABELING; CLINICAL ARTICLE; COMPARATIVE STUDY; CYSTIC LUNG LIGHT CHAIN DEPOSITION DISEASE; DEGRADATION; ELASTIC FIBER; ELASTIC TISSUE; ELASTOLYSIS; EXTRACELLULAR MATRIX; FEMALE; GIANT CELL; HISTIOCYTOSIS X; HUMAN; HUMAN TISSUE; LUNG CYST; LUNG DISEASE; LYMPHANGIOLEIOMYOMATOSIS; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZYMOGRAPHY;

ADULT; CYSTS; ELASTIN; EXTRACELLULAR MATRIX; FEMALE; HISTIOCYTOSIS, LANGERHANS-CELL; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG; LUNG DISEASES; LUNG TRANSPLANTATION; LYMPHANGIOLEIOMYOMATOSIS; MACROPHAGES; MALE;

EID: 58849144270     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00132007     Document Type: Article

References (29)

1. Randall RE, Williamson WC Jr, Mullinax F, Tung MY, Still WJ. Manifestations of systemic light chain deposition. Am J Med 1976; 60: 293-299.
2. Buxbaum J, Gallo G. Nonamyloidotic monoclonal immunoglobulin deposition disease. Light-chain, heavy-chain, and light- and heavy-chain deposition diseases. Hematol Oncol Clin North Am 1999; 13: 1235-1248.
3. Ganeval D, Noel LH, Preud'homme JL, Droz D, Grunfeld JP. Light-chain deposition disease: its relation with AL-type amyloidosis. Kidney Int 1984; 26: 1-9.
4. Lin J, Markowitz GS, Valeri AM, et al. Renal monoclonal immunoglobulin deposition disease: the disease spectrum. J Am Soc Nephrol 2001; 12: 1482-1492.
5. Morinaga S, Watanabe H, Gemma A, et al. Plasmacytoma of the lung associated with nodular deposits of immunoglobulin. Am J Surg Pathol 1987; 11: 989-995.
6. Stokes MB, Jagirdar J, Burchstin O, Kornacki S, Kumar A, Gallo G. Nodular pulmonary immunoglobulin light chain deposits with coexistent amyloid and nonamyloid features in an HIV-infected patient. Mod Pathol 1997; 10: 1059-1065.
7. Piard F, Yaziji N, Jarry O, et al. Solitary plasmacytoma of the lung with light chain extracellular deposits: a case report and review of the literature. Histopathology 1998; 32: 356-361.
8. Rostagno A, Frizzera G, Ylagan L, Kumar A, Ghiso J, Gallo G. Tumoral non-amyloidotic monoclonal immunoglobulin light chain deposits ("aggregoma"): presenting feature of B-cell dyscrasia in three cases with immunohistochemical and biochemical analyses. Br J Haematol 2002; 119: 62-69.
9. Khoor A, Myers JL, Tazelaar HD, Kurtin PJ. Amyloid-like pulmonary nodules, including localized light-chain deposition: clinicopathologic analysis of three cases. Am J Clin Pathol 2004; 121: 200-204.
10. Bhargava P, Rushin JM, Rusnock EJ, et al. Pulmonary light chain deposition disease: report of five cases and review of the literature. Am J Surg Pathol 2007; 31: 267-276.
11. Colombat M, Stern M, Groussard O, et al. Pulmonary cystic disorder related to light chain deposition disease. Am J Respir Crit Care Med 2006; 173: 777-780.
12. Travis WD, Borok Z, Roum JH, et al. Pulmonary Langerhans cell granulomatosis (histiocytosis X). A clinicopathologic study of 48 cases. Am J Surg Pathol 1993; 17: 971-986.
13. Corrin B, Liebow AA, Friedman PJ. Pulmonary lymphangiomyomatosis. A review. Am J Pathol 1975; 79: 348-382.
14. Fukuda Y, Basset F, Soler P, Ferrans VJ, Masugi Y, Crystal RG. Intraluminal fibrosis and elastic fiber degradation lead to lung remodeling in pulmonary Langerhans cell granulomatosis (histiocytosis X). Am J Pathol 1990; 137: 415-424.
15. Fukuda Y, Kawamoto M, Yamamoto A, Ishizaki M, Basset F, Masugi Y. Role of elastic fiber degradation in emphysema-like lesions of pulmonary lymphangiomyomatosis. Hum Pathol 1990; 21: 1252-1261.
16. Merrilees MJ, Hankin EJ, Black JL, Beaumont B. Matrix proteoglycans and remodelling of interstitial lung tissue in lymphangioleiomyomatosis. J Pathol 2004; 203: 653-660.
17. Birkedal-Hansen H, Moore WG, Bodden MK, et al. Matrix metalloproteinases: a review. Crit Rev Oral Biol Med 1993; 4: 197-250.
18. Shapiro SD, Kobayashi DK, Ley TJ. Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. J Biol Chem 1993; 268: 23824-23829.
19. Sato H, Takino T, Okada Y, et al. A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 1994; 370: 61-65.
20. Mercer RR, Crapo JD. Spatial distribution of collagen and elastin fibers in the lungs. J Appl Physiol 1990; 69: 756-765.
21. Keeling J, Herrera GA. Matrix metalloproteinases and mesangial remodeling in light chain-related glomerular damage. Kidney Int 2005; 68: 1590-1603.
22. Sepp N, Pichler E, Breathnach SM, Fritsch P, Hintner H. Amyloid elastosis: analysis of the role of amyloid P component. J Am Acad Dermatol 1990; 22: 27-34.
23. Yoneda K, Kanoh T, Nomura S, Ozaki M, Imamura S. Elastolytic cutaneous lesions in myeloma-associated amyloidosis. Arch Dermatol 1990; 126: 657-660.
24. Peyrol S, Gindre D, Cordier JF, Loire R, Grimaud JA. Characterization of the smooth muscle cell infiltrate and associated connective matrix of lymphangiomyomatosis. Immunohistochemical and ultrastructural study of two cases. J Pathol 1992; 168: 387-395.
25. Rodriguez-Pla A, Bosch-Gil JA, Rossello-Urgell J, Huguet-Redecilla P, Stone JH, Vilardell-Tarres M. Metalloproteinase-2 and -9 in giant cell arteritis: involvement in vascular remodeling. Circulation 2005; 112: 264-269.
26. Nikkari ST, Hoyhtya M, Isola J, Nikkari T. Macrophages contain 92-kD gelatinase (MMP-9) at the site of degenerated internal elastic lamina in temporal arteritis. Am J Pathol 1996; 149: 1427-1433.
27. Hayashi T, Rush WL, Travis WD, Liotta LA, Stetler-Stevenson WG, Ferrans VJ. Immunohistochemical study of matrix metalloproteinases and their tissue inhibitors in pulmonary Langerhans' cell granulomatosis. Arch Pathol Lab Med 1997; 121: 930-937.
28. Hayashi T, Fleming MV, Stetler-Stevenson WG, et al. Immunohistochemical study of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in pulmonary lymphangioleiomyomatosis (LAM). Hum Pathol 1997; 28: 1071-1078.
29. Matsui K, Takeda K, Yu ZX, Travis WD, Moss J, Ferrans VJ. Role for activation of matrix metalloproteinases in the pathogenesis of pulmonary lymphangioleiomyomatosis. Arch Pathol Lab Med 2000; 124: 267-275.