Macrophages contain 92-kd gelatinase (MMP-9) at the site of degenerated internal elastic lamina in temporal arteritis

American Journal of Pathology

Volumn 149, Issue 5, 1996, Pages 1427-1433

  Nikkari, Seppo Tapio ^a,b   Höyhtyä, Matti ^c   Isola, Jorma ^b   Nikkari, Tapio ^a  

^a UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^c Diabor Oy   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 4; GELATINASE;

ADULT; AGED; ARTICLE; BASEMENT MEMBRANE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; PRIORITY JOURNAL; TEMPORAL ARTERITIS;

AGED; COLLAGENASES; ELASTIC TISSUE; FEMALE; GELATINASES; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; MIDDLE AGED; NECROSIS; TEMPORAL ARTERIES; TEMPORAL ARTERITIS;

EID: 0029855635     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Ross R: The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993, 362:801-809
2. van der Wal AC, Becker AE, van der Loos CM, Das PK: Site of intimai rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation 1994, 89:36-44
3. Galis ZS, Sukhova GK, Lark MW, Libby P: Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994, 94:2493-2503
4. Henney AM, Wakeley PR, Davies MJ, Foster K, Hembry R, Murphy G, Humphries S: Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization. Proc Natl Acad Sci USA 1991, 88:8154-8158
5. Nikkari ST, O'Brien KD, Ferguson M, Hatsukami T, Welgus HG, Alpers CE, Clowes AW: Interstitial collagenase (MMP-1) expression in human carotid atherosclerosis. Circulation 1995, 92:1393-1398
6. Brown DL, Hibbs MS, Kearney M, Loushin C, Isner JM: Identification of 92-kD gelatinase in human coronary atherosclerotic lesions: association of active enzyme synthesis with unstable angina. Circulation 1995, 91: 2125-2131
7. Morris CR, Scheib JS: Fatal myocardial infarction resulting from coronary arteritis in a patient with polymyalgia rheumatica and biopsy-proved temporal arteritis. Arch Intern Med 1995, 154:1158-1160
8. Evans JM, O'Fallon WM, Hunder GG: Increased incidence of aortic aneurysm and dissection in giant cell (temporal) arteritis: a population-based study. Ann Intern Med 1995, 122:502-507
9. Rajala SA, Ahvenainen JE, Mattila KJ, Saarni MI: Incidence and survival rate in cases of biopsy-proven temporal arteritis. Scand J Rheumatol 1993, 22:289-291
10. Hunder GG, Bloch DA, Michel BA, Stevens MB, Arend WP, Calabrese LH, Edworthy SM, Fauci AS, Leavitt RY, Lie JT, Lightfoot RW, Masi AT, McShane DJ, Mills JA, Wallace SL, Zvaifler NJ: The American College of Rheumatology 1990 criteria for the classification of giant-cell arteritis. Arthritis Rheum 1990, 33:1122-1128
11. Soini Y, Hurskainen T, Höyhtyä M, Oikarinen A, Autio-Harmainen H: 72 kD and 92 kD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization. J Histochem Cytochem 1994, 42:945-951
12. Marguiles IMK, Höyhtyä M, Evans C, Stracke ML, Liotta LA, Stetler-Stevenson WG: Urinary type IV collagenase: elevated levels are associated with bladder transitional cell carcinoma. Cancer Epidemiol Biomed Prev 1992, 1:467-474
13. Fridman R, Fuerst TR, Bird RE, Höyhtyä M, Oelkuct M, Kraus S, Komarek D, Liotta LA, Berman ML, Stetler-Stevenson WG: Domain structure of human 72-kDa gelatinase/type IV collagenase: characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions. J Biol Chem 1992, 267:15398-15405
14. Klein RG, Hunder GG, Stanson AW, Sheps SG: Large artery involvement in giant cell (temporal) arteritis. Ann Intern Med 1975, 83:806-812
15. Matrisian LM: Metalloproteinases and their inhibitors in matrix remodeling. Trends Genet 1990, 6:121-125
16. Senior RM, Griffin GL, Fliszar CJ, Shapiro SD, Goldberg GI, Welgus HG: Human 92- and 72-kilodatton type IV collagenases are elastases. J Biol Chem 1991, 266: 7870-7875
17. Welgus HG, Campbell EJ, Cury JD, Eisen AZ, Senior RM, Wilhelm SM, Goldberg GI: Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development. J Clin Invest 1990, 86:1496-1502
18. Thompson RW, Holmes DR, Martens RA, Liao S, Botney MD, Mecham RP, Welgus HG, Parks WC: Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms: an elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages. J Clin Invest 1995, 96:318-326
19. Freestone T, Turner RJ, Coady A, Higman DJ, Greenhalgh RM, Powell JT: Inflammation and matrix metalloproteinases in the enlarging abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 1995, 15:1145-1151
20. Shapiro SD, Kobayashi DK, Ley TJ: Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. J Biol Chem 1993, 268:23824-23829
21. Okada Y, Watanabe S, Nakanishi I, Kishi J, Hayakawa T, Watorek W, Travis J, Nagase H: Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinases. FEBS Lett 1988, 229: 157-160
22. Clinton SK, Fleet JC, Loppnow H, Salomon RN, Clark BD, Cannon JG, Shaw AR, Dinarello CA, Libby P: Interleukin-1 gene expression in rabbit vascular tissue in vivo. Am J Pathol 1991, 138:1005-1014
23. Barath P, Fishbein MC, Cao J, Berenson J, Helfant RH, Forrester JS: Tumor necrosis factor gene expression in human vascular intimal smooth muscle cells detected by in situ hybridization. Am J Pathol 1990, 137:503-509
24. Ross R, Masuda J, Raines EW, Gown AM, Katsuda S, Sasahara M, Maiden LT, Masuko H, Sato H: Localization of PDGF-B protein in macrophages in all phases of atherogenesis. Science 1990, 248:1009-1012
25. Rekhter MD, Gordon D: Does platelet-derived growth factor-A chain stimulate proliferation of arterial mesenchymal cells in human atherosclerotic plaques. Circ Res 1994, 75:410-417
26. Bevilacqua MP, Schleef RR, Gimbrone MA, Loskutoff DJ: Regulation of the fibrinolytic system of cultured vascular endothelium by interleukin 1. J Clin Invest 1995, 78:587-591
27. Kenagy RD, Nikkari ST, Welgus HG, Clowes AW: Heparin inhibits the induction of three matrix metalloproteinases (stromelysin, 92-kD gelatinase, and collagenase) in primate arterial smooth muscle cells. J Clin Invest 1994, 93:1987-1993
28. Lohi J, Keski-Oja J: Calcium ionophores decrease pericellular gelatinolytic activity via inhibition of 92-kDa gelatinase expression and decrease of 72-kDa gelatinase activation. J Biol Chem 1995, 270:17602-17609
29. Zempo N, Kenagy RD, Au YPT, Bendeck M, Clowes MM, Reidy MA, Clowes AW: Matrix metalloproteinases of vascular wall cells are increased in balloon-injured rat carotid artery. J Vase Surg 1994, 20:209-217