Fish oil curtails the human action potential dome in a heterogeneous manner: Implication for arrhythmogenesis

International Journal of Cardiology

Volumn 132, Issue 1, 2009, Pages 138-140

  Verkerk, Arie O ^a   den Ruijter, Hester M ^a   de Jonge, Nicolaas ^b   Coronel, Ruben ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Action potential; Fish oil fatty acids; Heart failure; Heterogeneity; Nutrition

Indexed keywords

ACENOCOUMAROL; AMIODARONE; BISOPROLOL FUMARATE; BUMETANIDE; CANDESARTAN HEXETIL; CAPTOPRIL; DIGOXIN; EPLERENONE; FISH OIL; FUROSEMIDE; ICOSAPENTAENOIC ACID; OLEIC ACID; OMEGA 3 FATTY ACID; POTASSIUM; SPIRONOLACTONE;

ADULT; AGED; ARRHYTHMOGENESIS; ARTICLE; CARDIOMYOPATHY; CASE REPORT; CELL HETEROGENEITY; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DISPERSION; EXPLANT; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HEART TRANSPLANTATION; HUMAN; HUMAN CELL; ISCHEMIC HEART DISEASE; MALE; MORPHOLOGY; PRIORITY JOURNAL;

ACTION POTENTIALS; AGED; ARRHYTHMIAS, CARDIAC; EICOSAPENTAENOIC ACID; FATTY ACIDS, OMEGA-3; HEART TRANSPLANTATION; HUMANS; MALE; MIDDLE AGED; MYOCARDIUM; MYOCYTES, CARDIAC; PERFUSION;

EID: 58849141375     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2007.07.145     Document Type: Article

References (9)

1. Den Ruijter H.M., Berecki G., Opthof T., et al. Pro- and antiarrhythmic properties of a diet rich in fish oil. Cardiovasc Res 73 (2007) 316-325
2. Macleod J.C., Macknight A.D.C., and Rodrigo G.C. The electrical and mechanical response of adult guinea pig and rat ventricular myocytes to omega-3 polyunsaturated fatty acids. Eur J Pharmacol 356 (1998) 261-270
3. Fu G.S., Meissner A., and Simon R. Repolarization dispersion and sudden cardiac death in patients with impaired left ventricular function. Eur Heart J 18 (1997) 281-289
4. Yan G.X., Joshi A., Guo D., et al. Phase 2 reentry as a trigger to initiate ventricular fibrillation during early acute myocardial ischemia. Circulation 110 (2004) 1036-1041
5. Antzelevitch C. Brugada syndrome. Pacing Clin Electrophysiol 29 (2006) 1130-1159
6. Janse M.J., and Wit A.L. Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction. Physiol Rev 69 (1989) 1049-1169
7. Veldkamp M.W., Verkerk A.O., van Ginneken A.C.G., et al. Norepinephrine induces action potential prolongation and early afterdepolarizations in ventricular myocytes isolated from human end-stage failing hearts. Eur Heart J 22 (2001) 955-963
8. + currents in isolated human ventricular myocytes from patients with terminal heart failure. Circ Res 73 (1993) 379-385
9. Montfoort A., van der Werf L., Hartog J.M., et al. The influence of fish oil diet and norepinephrine treatment on fatty acid composition of rat heart phospholipids and the positional fatty acid distribution in phosphatidylethanolamine. Basic Res Cardiol 81 (1986) 289-302