Parkin expression profile in dopamine D3 receptor knock-out mice brains

Neurochemical Research

Volumn 34, Issue 2, 2009, Pages 327-332

  D'Agata, Velia ^a   Tiralongo, Adriana ^a   Castorina, Alessandro ^a   Leggio, Gian Marco ^a   Micale, Vincenzo ^a   Carnazza, Maria Luisa ^a   Drago, Filippo ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Autosomic recessive juvenile parkinsonism; Dopamine D3 receptor; Parkin exons expression; Parkin isoforms

Indexed keywords

DOPAMINE 3 RECEPTOR; MESSENGER RNA; PARKIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; EXON; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; EXONS; GENE EXPRESSION PROFILING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, DOPAMINE D3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA; MUS;

EID: 58849135359     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-008-9781-y     Document Type: Article

References (28)

1. T Kitada S Asakawa N Hattori H Matsumine Y Yamamura S Minoshima 1998 Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism Nature 392 605 608 10.1038/33416
2. H Takahashi E Ohama S Suzuki Y Horikawa A Ishikawa T Morita 1994 Familial juvenile parkinsonism: clinical and pathologic study in a family Neurology 44 437 441
3. CB Lücking A Dürr V Bonifati J Vaughan G De Michele T Gasser BS Harhangi G Meco P Denèfle NW Wood Y Agid A Brice French Parkinson's Disease Genetics Study Group & European Consortium on Genetic Susceptibility in Parkinson's Disease 2000 Association between early-onset Parkinson's disease and mutations in the parkin gene N Engl J Med 342 1560 1567 10.1056/NEJM200005253422103
4. C Klein PP Pramstaller B Kis CC Page M Kann J Leung 2000 Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: expanding the phenotype Ann Neurol 48 65 71 10.1002/1531-8249(200007)48:1<65::AID- ANA10>3.0.CO;2-L
5. MR Cookson 2003 Parkin's substrates and the pathways leading to neuronal damage Neuromolecular Med 3 1 13 10.1385/NMM:3:1:1
6. Y Imai M Soda R Takahashi 2000 Parkin suppresses unfolded protein stress- induced cell death through its E3 ubiquitin-protein ligase activity J Biol Chem 275 35661 35664 10.1074/jbc.C000447200
7. H Shimura N Hattori S Kubo Y Mizuno S Asakawa S Minoshima 2000 Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase Nat Genet 25 302 305 10.1038/77060
8. CC Stichel M Augustin K Kühn XR Zhu P Engels C Ullmer 2000 Parkin expression in the adult mouse brain Eur J Neurosci 12 4181 4194 10.1046/j.1460-9568.2000.01314.x
9. T Kitada S Asakawa S Minoshima Y Mizuno N Shimizu 2000 Molecular cloning, gene expression, and identification of a splicing variant of the mouse parkin gene Mamm Genome 11 417 421 10.1007/s003350010080
10. Y Sunada F Saito K Matsumura T Shimizu 1998 Differential expression of the parkin gene in the human brain and peripheral leukocytes Neurosci Lett 254 180 182 10.1016/S0304-3940(98)00697-1
11. V D'Agata W Zhao S Cavallaro 2000 Cloning and distribution of the rat parkin mRNA Brain Res Mol Brain Res 75 345 349 10.1016/S0169-328X(99)00286-7
12. JN Joyce 2001 Dopamine D3 receptor as a therapeutic target for antipsychotic and antiparkinsonian drugs Pharmacol Ther 90 231 259 10.1016/S0163-7258(01)00139-5
13. O Civelli JR Bunzow DK Grandy 1993 Molecular diversity of the dopamine receptors Annu Rev Pharmacol Toxicol 33 281 307 10.1146/annurev.pa.33.040193. 001433
14. B Le Foll J Diaz P Sokoloff 2005 Neuroadaptations to hyperdopaminergia in dopamine D3 receptor-deficient mice Life Sci 76 1281 1296 10.1016/j.lfs.2004. 09.018
15. C Scherfler NL Khan N Pavese L Eunson E Graham AJ Lees 2004 Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism Brain 127 1332 1342 10.1093/brain/awh150
16. JD Joseph YM Wang PR Miles EA Budygin R Picetti RR Gainetdinov 2002 Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors Neuroscience 112 39 49 10.1016/S0306-4522(02) 00067-2
17. SR Sriram X Li HS Ko KK Chung E Wong KL Lim 2005 Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin Hum Mol Genet 14 2571 2586 10.1093/hmg/ddi292
18. C Wang JM Tan MW Ho N Zaiden SH Wong CL Chew 2005 Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease-linked point mutations J Neurochem 93 422 431 10.1111/j.1471-4159.2005.03023.x
19. C Wang HS Ko B Thomas F Tsang KC Chew SP Tay 2005 Stress- induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function Hum Mol Genet 14 3885 3897 10.1093/hmg/ddi413
20. MS Goldberg SM Fleming JJ Palacino C Cepeda HA Lam A Bhatnagar 2003 Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons J Biol Chem 278 43628 43635 10.1074/jbc.M308947200
21. MM Bradford 1976 A rapid and sensitive method for the quantification of micrograms quantities of proteins utilizing the principle of protein dye binding Anal Biochem 72 248 254 10.1016/0003-2697(76)90527-3
22. A Pascale I Fortino S Govoni M Trabucchi WC Wetsel F Battaini 1996 Functional impairment in protein kinase C by RACK1 (receptor for activated C kinase 1) deficiency in aged rat brain cortex J Neurochem 67 2471 2477
23. J Sovago B Makkai B Gulyas H Hall 2005 Autoradiographic mapping of dopamine-D2/D3 receptor stimulated [35S]GTPgammaS binding in the human brain Eur J Neurosci 22 65 71 10.1111/j.1460-9568.2005.04192.x
24. D Viaggiano LA Ruocco AG Sadile 2003 Dopamine phenotype and behaviour in animal models: in relation to attention deficit hyperactivity disorder Neurosci Biobehav Rev 27 623 637 10.1016/j.neubiorev.2003.08.006
25. MR Cookson 2005 The biochemistry of Parkinson's disease Annu Rev Biochem 74 29 52 10.1146/annurev.biochem.74.082803.133400
26. JM Horowitz VA Vernace J Myers MK Stachowiak DW Hanlon GS Fraley 2001 Immunodetection of Parkin protein in vertebrate and invertebrate brains: a comparative study using specific antibodies J Chem Neuroanat 21 75 93 10.1016/S0891-0618(00)00111-3
27. MJ LaVoie BL Ostaszewski A Weihofen MG Schlossmacher DJ Selkoe 2005 Dopamine covalently modifies and functionally inactivates parkin Nat Med 11 1214 1221 10.1038/nm1314
28. ES Wong JM Tan C Wang Z Zhang SP Tay N Zaiden 2007 Relative sensitivity of parkin and other cysteine containing enzymes to stress-induced solubility alterations J Biol Chem 282 12310 12318 10.1074/jbc.M609466200