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Volumn 58, Issue 2, 2009, Pages 189-195

Aberrant extrathymic T cell receptor gene rearrangement in the small intestinal mucosa: A risk factor for coeliac disease?

Author keywords

[No Author keywords available]

Indexed keywords

CD2 ANTIGEN; CD7 ANTIGEN; GLUTEN; MESSENGER RNA; RAG1 PROTEIN; RAG2 PROTEIN; RIBOSOME RNA;

EID: 58849099617     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gut.2007.125526     Document Type: Article
Times cited : (7)

References (28)
  • 1
    • 0037880603 scopus 로고    scopus 로고
    • HLA in coeliac disease: Unravelling the complex genetics of a complex disorder
    • Louka AS, Sollid LM. HLA in coeliac disease: unravelling the complex genetics of a complex disorder. Tissue Antigens 2003:61:105-17.
    • (2003) Tissue Antigens , vol.61 , pp. 105-117
    • Louka, A.S.1    Sollid, L.M.2
  • 2
    • 0036715684 scopus 로고    scopus 로고
    • Coeliac disease: Dissecting a complex inflammatory disorder
    • Sollid LM. Coeliac disease: dissecting a complex inflammatory disorder. Nat Rev Immunol 2002;2:647-55.
    • (2002) Nat Rev Immunol , vol.2 , pp. 647-655
    • Sollid, L.M.1
  • 3
    • 0027394036 scopus 로고
    • + α/β cells in the lamina propria but proliferation (Ki-67) of α/βand gamma;/δ cells in the epithelium
    • + α/β cells in the lamina propria but proliferation (Ki-67) of α/βand gamma;/δ cells in the epithelium. Eur J Immunol 1993;23:505-10.
    • (1993) Eur J Immunol , vol.23 , pp. 505-510
    • Halstensen, T.S.1    Brandtzaeg, P.2
  • 4
    • 0037373255 scopus 로고    scopus 로고
    • + T cell responses: Identification of a novel gliadin-derived HLA-A2-restricted epitope
    • + T cell responses: identification of a novel gliadin-derived HLA-A2-restricted epitope. J Immunol 2003;170: 2719-26.
    • (2003) J Immunol , vol.170 , pp. 2719-2726
    • Gianfrani, C.1    Troncone, R.2    Mugione, P.3
  • 5
    • 0028828948 scopus 로고
    • Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or ThO profile dominated by interferon gamma
    • Nilsen EM, Lundin KE, Krajci P, et al. Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or ThO profile dominated by interferon gamma. Gut 1995:37:766-76.
    • (1995) Gut , vol.37 , pp. 766-776
    • Nilsen, E.M.1    Lundin, K.E.2    Krajci, P.3
  • 6
    • 0029131501 scopus 로고
    • Intraepithelial lymphocytes. Evidence for regional specialization and extrathymic T cell maturation in the human gut epithelium
    • Lundqvist C, Baranov V, Hammarstrom S, et al. Intraepithelial lymphocytes. Evidence for regional specialization and extrathymic T cell maturation in the human gut epithelium. Int Immunol 1995;7:1473-87.
    • (1995) Int Immunol , vol.7 , pp. 1473-1487
    • Lundqvist, C.1    Baranov, V.2    Hammarstrom, S.3
  • 8
    • 0032972224 scopus 로고    scopus 로고
    • Changing jejunal γδ T cell receptor |TCR|-bearing intraepithelial lymphocyte density in coeliac disease
    • Iltanen S, Holm K, Ashorn M, et al. Changing jejunal γδ T cell receptor |TCR|-bearing intraepithelial lymphocyte density in coeliac disease. Clin Exp Immunol 1999;117:51-5.
    • (1999) Clin Exp Immunol , vol.117 , pp. 51-55
    • Iltanen, S.1    Holm, K.2    Ashorn, M.3
  • 9
    • 0027414723 scopus 로고
    • + intraepithelial lymphocytes correlate with the grade of villous atrophy in coeliac patients on a long term normal diet
    • + intraepithelial lymphocytes correlate with the grade of villous atrophy in coeliac patients on a long term normal diet. Gut 1993;34:208-14.
    • (1993) Gut , vol.34 , pp. 208-214
    • Kutlu, T.1    Brousse, N.2    Rambaud, C.3
  • 10
    • 0025204503 scopus 로고
    • Intestinal γδ receptor-bearing T lymphocytes in celiac disease and inflammatory bowel diseases in children. Constant increase in celiac disease
    • Savilahti E, Arato A, Verkasalo M. Intestinal γδ receptor-bearing T lymphocytes in celiac disease and inflammatory bowel diseases in children. Constant increase in celiac disease. Pediatr Res 1990;28:579-81.
    • (1990) Pediatr Res , vol.28 , pp. 579-581
    • Savilahti, E.1    Arato, A.2    Verkasalo, M.3
  • 11
    • 0034058876 scopus 로고    scopus 로고
    • Selective expansion of intraepithelial lymphocytes expressing the HLA-E-specific natural killer receptor C094 in celiac disease
    • Jabri B, de Serre NP, Cellier C, et al. Selective expansion of intraepithelial lymphocytes expressing the HLA-E-specific natural killer receptor C094 in celiac disease. Gastroenterology 2000;118:867-79.
    • (2000) Gastroenterology , vol.118 , pp. 867-879
    • Jabri, B.1    de Serre, N.P.2    Cellier, C.3
  • 12
    • 0036728160 scopus 로고    scopus 로고
    • Paradoxical coexpression of proinflammatory and down-regulatory cytokines in intestinal T cells in childhood celiac disease
    • Forsberg G, Hernell 0, Melgar S, et al. Paradoxical coexpression of proinflammatory and down-regulatory cytokines in intestinal T cells in childhood celiac disease. Gastroenterology 2002;123:667- 78.
    • (2002) Gastroenterology , vol.123 , pp. 667-678
    • Forsberg, G.1    Hernell 02    Melgar, S.3
  • 13
    • 4444251461 scopus 로고    scopus 로고
    • A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease
    • Hue S, Mention JJ, Monteiro RC, et al. A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease. Immunity 2004;21:367-77.
    • (2004) Immunity , vol.21 , pp. 367-377
    • Hue, S.1    Mention, J.J.2    Monteiro, R.C.3
  • 14
    • 4444240035 scopus 로고    scopus 로고
    • Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokme-activated killer cells in celiac disease
    • Meresse B, Chen Z, Olszewski C, et al. Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokme-activated killer cells in celiac disease. Immunity 2004;21:357-66.
    • (2004) Immunity , vol.21 , pp. 357-366
    • Meresse, B.1    Chen, Z.2    Olszewski, C.3
  • 15
    • 33646675580 scopus 로고    scopus 로고
    • Reprogramming of CTLs into natural killerlike cells in celiac disease
    • Meresse B, Curran SA, Ciszewski C, et al. Reprogramming of CTLs into natural killerlike cells in celiac disease. J Exp Med 2006;203:1343-55.
    • (2006) J Exp Med , vol.203 , pp. 1343-1355
    • Meresse, B.1    Curran, S.A.2    Ciszewski, C.3
  • 16
    • 0141920522 scopus 로고    scopus 로고
    • Extrathymic TCR gene rearrangement in human small intestine: Identification of new splice forms of recombination activating gene-1 mRNA with selective tissue expression
    • Bas A, Hammarstrom SG, Hammarstrom ML. Extrathymic TCR gene rearrangement in human small intestine: identification of new splice forms of recombination activating gene-1 mRNA with selective tissue expression. J Immunol 2003;171:3359-71.
    • (2003) J Immunol , vol.171 , pp. 3359-3371
    • Bas, A.1    Hammarstrom, S.G.2    Hammarstrom, M.L.3
  • 17
    • 2942700135 scopus 로고    scopus 로고
    • Utility of the housekeeping genes 18S rRNA, beta-actin and glyceraldehyde-3-phosphate- dehydrogenase for normalization in real-time quantitative reverse transcriptase-polymerase chain reaction analysis of gene expression in human T lymphocytes
    • Bas A, Forsberg G, Hammarstrom S, et al. Utility of the housekeeping genes 18S rRNA, beta-actin and glyceraldehyde-3-phosphate- dehydrogenase for normalization in real-time quantitative reverse transcriptase-polymerase chain reaction analysis of gene expression in human T lymphocytes. Scand J Immunol 2004;59:566-73.
    • (2004) Scand J Immunol , vol.59 , pp. 566-573
    • Bas, A.1    Forsberg, G.2    Hammarstrom, S.3
  • 18
    • 0029069326 scopus 로고
    • RAG1 and RAG2 expression in human intestinal epithelium: Evidence of extrathymic T cell differentiation
    • Lynch S, Kelleher D, McManus R, et al. RAG1 and RAG2 expression in human intestinal epithelium: evidence of extrathymic T cell differentiation. Eur J Immunol 1995;25:1143-7.
    • (1995) Eur J Immunol , vol.25 , pp. 1143-1147
    • Lynch, S.1    Kelleher, D.2    McManus, R.3
  • 19
    • 10344263928 scopus 로고    scopus 로고
    • Intestinal αβ T cells differentiate and rearrange antigen receptor genes in situ in the human infant
    • Williams AM, Bland PW, Phillips AC, et al. Intestinal αβ T cells differentiate and rearrange antigen receptor genes in situ in the human infant. J Immunol 2004;173:7190-9.
    • (2004) J Immunol , vol.173 , pp. 7190-7199
    • Williams, A.M.1    Bland, P.W.2    Phillips, A.C.3
  • 20
    • 2942642613 scopus 로고    scopus 로고
    • Presence of bacteria and innate immunity of intestinal epithelium in childhood celiac disease
    • Forsberg G, Fahlgren A, Horstedt P, et al. Presence of bacteria and innate immunity of intestinal epithelium in childhood celiac disease. Am J Gastroenterol 2004;99:894-904.
    • (2004) Am J Gastroenterol , vol.99 , pp. 894-904
    • Forsberg, G.1    Fahlgren, A.2    Horstedt, P.3
  • 21
    • 33644822609 scopus 로고    scopus 로고
    • Gut microflora associated characteristics in children with celiac disease
    • Tjellstrom B, Stenhammar L, Hogberg L, et al. Gut microflora associated characteristics in children with celiac disease. Am J Gastroenterol 2005:100:2784-8.
    • (2005) Am J Gastroenterol , vol.100 , pp. 2784-2788
    • Tjellstrom, B.1    Stenhammar, L.2    Hogberg, L.3
  • 23
    • 29244454225 scopus 로고    scopus 로고
    • Orchestrated leak provokes a thymus reassessment
    • Hayday A. Orchestrated leak provokes a thymus reassessment. Nat Immunol 2006;7:9-11.
    • (2006) Nat Immunol , vol.7 , pp. 9-11
    • Hayday, A.1
  • 24
    • 0035162229 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes: Exploring the Third Way in immunology
    • Hayday A, Theodoridis E, Ramsburg E, et al. Intraepithelial lymphocytes: exploring the Third Way in immunology. Nat Immunol 2001;2:997-1003.
    • (2001) Nat Immunol , vol.2 , pp. 997-1003
    • Hayday, A.1    Theodoridis, E.2    Ramsburg, E.3
  • 25
    • 13544259003 scopus 로고    scopus 로고
    • Extrathymic hemopoietic progenitors committed to T cell differentiation in the adult mouse
    • Arcangali ML, Lancrin C, Lambolez F, et al. Extrathymic hemopoietic progenitors committed to T cell differentiation in the adult mouse. J Immunol 2005;174:1980-8.
    • (2005) J Immunol , vol.174 , pp. 1980-1988
    • Arcangali, M.L.1    Lancrin, C.2    Lambolez, F.3
  • 26
    • 29244468256 scopus 로고    scopus 로고
    • The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs
    • Lambolez F, Arcangeli ML, Joret AM, et al. The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs. Nat Immunol 2006;7:76-82.
    • (2006) Nat Immunol , vol.7 , pp. 76-82
    • Lambolez, F.1    Arcangeli, M.L.2    Joret, A.M.3
  • 27
    • 6944232241 scopus 로고    scopus 로고
    • + human small intestinal T cells are decreased in coeliac patients, with CD8 expression downregulated on intraepithelial T cells in the active disease
    • + human small intestinal T cells are decreased in coeliac patients, with CD8 expression downregulated on intraepithelial T cells in the active disease. Eur J Gastroenterol Hepatol 2004;16:961-8.
    • (2004) Eur J Gastroenterol Hepatol , vol.16 , pp. 961-968
    • Carton, J.1    Byrne, B.2    Madrigal-Estebas, L.3
  • 28
    • 0034053959 scopus 로고    scopus 로고
    • Intestinal inflammation observed in IL-2R/IL-2 mutant mice is associated with impaired intestinal T lymphopoiesis
    • Poussier P, Ning T, Chen J, et al. Intestinal inflammation observed in IL-2R/IL-2 mutant mice is associated with impaired intestinal T lymphopoiesis. Gastroenterology 2000;118:880-91.
    • (2000) Gastroenterology , vol.118 , pp. 880-891
    • Poussier, P.1    Ning, T.2    Chen, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.