Magnesium and calcium in exhaled breath condensate of children with asthma and gastroesophageal reflux disease

Journal of Clinical Laboratory Analysis

Volumn 23, Issue 1, 2009, Pages 34-39

  Dodig, Slavica ^a   Vlašić, Željka ^a   Čepelak, Ivana ^b   Topić, Renata Zrinski ^a   Turkalj, Mirjana ^a   Nogalo, Boro ^a  

^a SREBRNJAK CHILDREN S HOSPITAL   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Asthma; Calcium; Exhaled breath condensate; Gastroesophageal reflux disease; Magnesium

Indexed keywords

CALCIUM; MAGNESIUM;

ADOLESCENT; ARTICLE; ASTHMA; CHILD; CONTROL GROUP; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE MARKER; EXPIRED AIR; FEMALE; GASTROESOPHAGEAL REFLUX; HUMAN; MAJOR CLINICAL STUDY; MALE; SCHOOL CHILD; SPECTROPHOTOMETRY;

ADOLESCENT; ASTHMA; BIOLOGICAL MARKERS; BREATH TESTS; CALCIUM; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CHILD; FEMALE; GASTROESOPHAGEAL REFLUX; HUMANS; MAGNESIUM; MALE; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY; STATISTICS, NONPARAMETRIC;

EID: 58849093335     PISSN: 08878013     EISSN: 10982825     Source Type: Journal    
DOI: 10.1002/jcla.20286     Document Type: Article

References (48)

1. 1.Malpuech-Brugere C, Rock E, Astier C, Nowacki W, Mazur A, Rayssiguier Y. Exacerbated immune stress response during experimental magnesium deficiency results from abnormal cell calcium homeostasis. Life Sci 1998;63:1815-1821.
2. Zaloga GP, Roberts PR. Calcium, phosphorus and magnesium disorders. In: SM Ayres, NA Greuvik, PR Holbrook, et al., editors. Textbook of Critical Care, fourth edition. Philadelphia: Saunders. 2000. 905-928.
3. Spivey WH, Skobellof EM, Levin RM. Effect of magnesium chloride on rabbit bronchial smooth muscle. Ann Emerg Med 1990;19:1107-1112.
4. Ciarallo L, Sauer A, Shannon MW. Intravenous magnesium therapy for moderate to severe pediatric asthma: Results of a randomized, placebo-controlled trial. J Pediatr 1996;129:809-814.
5. Iseri LT, French JH. Magnesium: Nature's physiologic calcium blocker. Am Heart J 1984;108:188-193.
6. Cairns CB, Kraft M. Magnesium attenuates the neutrophils respiratory burst in adult asthmatic patients. Acad Emerg Med 1996;3:1093-1097.
7. Hasebe N. Oxidative stress and magnesium. Clin Calcium 2005;15:194-202.
8. Patel T, Bronk SF, Gores GJ. Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes. J Clin Invest 1994;94:2183-2192.
9. Rayssiguer Y, Mazur A. Magnesium and inflammation: Lessons from animal models. Clin Calcium 2005;15:245-248.
10. Bussiere FI, Gueux E, Rock E, Girardeau JP, Tridon A, Mazur A. Increased phagocytosis and production of reactive oxygen species by neutrophil during magnesium deficiency in rats and inhibition by high magnesium concentration. Br J Nutr 2002;87:107-113.
11. Britton J, Pavord I, Richards K, et al. Dietary magnesium, lung function, wheezing, and airway hyperreactivity in a random adult population sample. Lancet 1994;344:357-362.
12. Jenner R, Body R. Intravenous magnesium in COPD. Emerg Med J 2004;21:203.
13. Emelyanov A, Fedoseev G, Barnes PJ. Reduced intracellular magnesium concentration in asthmatic patients. Eur Respir J 1999;13:38-40.
14. Mirčetić RN, Dodig S, Raos M, Petres B, Čepelak I. Magnesium concentration in plasma, leukocytes and urine of children with intermittent asthma. Clin Chim Acta 2001;312:197-203.
15. de Valk HW, Kok PT, Struyvenberg A, et al. Extracellular and intracellular magnesium concentrations in asthmatic patients. Eur Respir J 1993;6:1122-1125.
16. Montuschi P. Analysis of exhaled breath condensate in respiratory medicine: Methodological aspects and potential clinical applications. Ther Adv Respir Dis 2007;1:5-23.
17. Horváth I, Hunt J, Barnes PJ. On behalf of the ATS/ERS Task Force on Exhaled Breath Condensate. Exhaled breath condensate: Methodological recommendations and unresolved questions. Eur Respir J 2005;26:523-548.
18. Hunt J. Exhaled breath condensate: An evolving tool for noninvasive evaluation of lung disease. J Allergy Clin Immunol 2002;110:28-34.
19. Montuschi P. Indirect monitoring of lung inflammation. Nat Rev Drug Discov 2002;1:238-242.
20. Montuschi P, Barnes PJ. Analysis of exhaled breath condensate for monitoring airway inflammation. Trends Pharmacol Sci 2002;23:232-237.
21. Kharitonov SA, Barnes PJ. Exhaled markers of pulmonary disease. Am J Respir Crit Care Med 2001;163:1693-1722.
22. Hunt J, Yu Y, Burns J, et al. Identification of acid reflux cough using serial assays of exhaled breath condensate pH. Cough 2006;2:3-10. http://www.pubmedcentral.nih.gov/articlerender.fcgi7tool =pubmed&pubmedid = 16608520, available on April 17, 2008.
23. Čepelak I, Dodig S. Exhaled breath condensate: A new method for lung disease diagnosis. Clin Chem Lab Med 2007;45:945-952.
24. Montuschi P, Mondino C, Koch P, Barnes PJ, Ciabattoni G. Effects of a leukotriene receptor antagonist on exhaled leukotriene E4 and prostanoids in children with asthma. J Allergy Clin Immunol 2006;118:347-353.
25. Stordal K, Johannesdottir GB, Bentsen BS, Carlsen KC, Standvik L. Asthma and overweight are associated with symptoms of gastrooesophageal reflux. Acta Paediatr 2006;95:1197-1201.
26. Global Strategy for Asthma Management and Prevention. Revision 2006. www.ginasthma.com/Guidelineitem.asp, available on December 29, 2006.
27. Semeniuk J, Kaczmarski M. Gastroesophageal reflux (GER) in children and adolescents with regard to food intolerance. Adv Med Sci 2006;51:321-326.
28. Bousquet J, Jeffery PK, Busse WW, Johnson M, Vignola AM. Asthma-from bronchoconstriction to airways inflammation and remodeling. Am J Respir Crit Care Med 2000;161:1720-1745.
29. Dai JM, Kuo K-H, Leo JM, Paré PD, van Breemen C, Lee C-H. Acetylcholine-induced asynchronous calcium waves in intact human bronchial muscle bundle. Am J Respir Cell Mol Biol 2007;36:600-608.
30. Trian T, Benard G, Begueret H, et al. Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma. J Exp Med 2007;204:3173-3181.
31. Kakish KS. Serum magnesium levels in asthmatic children during and between exacerbations. Arch Pediatr Adolesc Med 2001; 155:181-183.
32. Saris NEL, Mervaala E, Karppanen H, Khawaja J, Lewenstam A. Magnesium: An update on physiological, clinical and analytical aspects. Clin Chim Acta 2000;294:1-26.
33. Elin RJ. Magnesium: The fifth but forgotten electrolyte. Am J Clin Pathol 1994;102:616-622.
34. Ruljančić N, Popović-Grle S, Rumenjak V, et al. COPD: Magnesium in the plasma and polymorphonuclear cells of patients. Chronic Obstructive Pulm Dis 2007;4:41-17.
35. Rijkers GT, Henriquez N, Griffionen AW. Intracellular magnesium movements and lymphocyte activation. Magnes Res 1993;6:205-213.
36. McKee MD, Cecco SA, Niemela JE, et al. Effects of interleukin 2 therapy on lymphocyte magnesium levels. J Lab Clin Med 2002;139:5-12.
37. Hashimoto Y, Nishimura Y, Maeda H, Yokoyama M. Assessment of magnesium status in patients with bronchial asthma. J Asthma 2000;37:489-496.
38. Rosias PP, Dompeling E, Dentener MA, et al. Childhood asthma: Exhaled markers of airway inflammation, asthma control score, and lung function tests. Pediatr Pulmonol 2004;38:107-114.
39. Montuschi P, Corradi M, Ciabattoni G, Nightingale J, Kharitonov SA, Barnes PJ. Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients. Am J Respir Crit Care Med 1999;160:216-220.
40. Borrill Z, Starkey C, Vestbo J, Singh D. Reproducibility of exhaled breath condensate pH in chronic obstructive pulmonary disease. Eur Respir J 2005;25:269-274.
41. Montuschi P, Collins JV, Ciabattoni G, et al. Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers. Am J Respir Crit Care Med 2000;162:1175-1177.
42. Redington AE. Exhaled breath condensate pH and exhaled nitric oxide in allergic asthma and in cystic fibrosis. Thorax 2005;60:22-26.
43. Montuschi P, Kharitonov SA, Ciabattoni G, et al. Exhaled 8-isoprostane as a new non invasive biomarker of oxidative stress in cystic fibrosis. Thorax 2000;55:205-209.
44. Carpagnano GE, Spanevello A, Cruci C, et al. IL-2, TNF-alpha, and leptin: Local versus systemic concentration in NSCLC patients. Oncol Res 2007;16:375-381.
45. Niimi A, Nguyen LT, Usmani O, Mann B, Chung KF. Reduced pH and chloride levels in exhaled breath condensate of patients with chronic cough. Thorax 2004;59:608-612.
46. Effros RM, Peterson B, Casaburi R, et al. Epithelial lining fluid solute concentrations in chronic obstructive lung disease patients and normal subjects. J Appl Physiol 2005;99:1286-1292.
47. Effros RM, Dunning III MB, Biller J, Shaker R. The promise and perils of exhaled breath condensate. Am J Physiol Lung Cell Mol Physiol 2004;287;L1037-1080.
48. Khoshoo V, Haydel Jr R, Saturno E. Gastroesophageal reflux disease and asthma in children. Curr Gastroenterol Rep 2006;8:237-243.