Efficient and versatile synthesis of 2,3-Dialkylimidazo[4,5-b]quinolin-9- ols by microwave-assisted one-pot Beckmann rearrangement

Synthesis

Volumn , Issue 22, 2008, Pages 3569-3578

  Hwang, Bo Hyun ^a,b   Choi, Eun Bok ^a   Lee, Hyeon Kyu ^a   Yang, Hee Cheol ^a   Chung, Bong Young ^b   Pak, Chwang Siek ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

^b Korea University   (South Korea)

Author keywords

Cyclization; Imidazoquinolinol; Microwave; One pot Beckmann rearrangement; Oxazoloquinoline

Indexed keywords

ALKYLATION; AMINATION; AMINES; CYCLIZATION; ETHANOL; MICROWAVES; ORGANIC COMPOUNDS; OXYGEN;

AMINO GROUPS; HYDROXY GROUPS; IMIDAZOQUINOLINOL; MICROWAVE; MICROWAVE-ASSISTED; MINOR PRODUCTS; ONE-POT BECKMANN REARRANGEMENT; OXAZOLOQUINOLINE; SECONDARY AMINES; TAUTOMERIC FORMS;

GROUP TECHNOLOGY;

2 ALKYL N ALKYLOXAZOLO[4,5-C]QUINOLIN 4 AMINE; 2 METHYL 3 PHENYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 2 METHYL 3 PROPYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 2 METHYL 4 MORPHOLINOOXAZOLO[4, 5-C]QUINOLINE; 2 METHYL N PROPYLOXAZOLO[4, 5-C]QUINOLIN 4 AMINE; 2,3 DIALKYLIMIDAZO[4,5-B]QUINOLIN 9 OL; 2,5 DIMETHYL 3 PHENYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 2,5 DIMETHYL 3 PROPYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 3 ALKYL N ALKYLISOOXAZOLO[4,5-C]QUINOLIN 4 AMINE; 3 ALLYL 2,5 DIMETHYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 3 ALLYL 5,8 DICHLORO 2 METHYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 3 ISOBUTYL 2 PHENYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 3 ISOPROPYL 2,6,8 TRIMETHYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 3 METHYL N PROPYLISOXAZOLO[4, 5-C]QUINOLIN 4 AMINE; 5 CHLORO 2 ETHYL 3 ISOPROPYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 5,6 DICHLORO 2,3 DIMETHYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 6 CHLORO 2 ETHYL N ISOPROPYLOXAZOLO[4, 5-C]QUINOLIN 4 AMINE; 7 (TERT BUTYL) 2 METHYL 3 PENTYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 7 (TERT BUTYL) 3 (2,2 DIPHENYLPROPYL) 2 METHYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 7 (TERT BUTYL) 3 CYCLOBUTYL 2 METHYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 7 METHOXY 2,3 DIMETHYL 3H IMIDAZO[4, 5-B]QUINOLIN 9 OL; 8 TERT BUTYL N CYCLOBUTYL 2 METHYL N (2,2 DIPHENYLPROPYL)OXAZOLO[4, 5-C]QUINOLIN 4 AMINE; 8 TERT BUTYL N CYCLOBUTYL 2 METHYLOXAZOLO[4, 5-C]QUINOLIN 4 AMINE; 8 TERT BUTYL N CYCLOBUTYL 3 METHYLISOXAZOLO[4, 5-C]QUINOLIN 4 AMINE; N ALLYL 6,9 DICHLORO 2 METHYLOXAZOLO[4, 5-C]QUINOLIN 4 AMINE; N ALLYL 6,9 DICHLORO 3 METHYLISOXAZOLO[4, 5-C]QUINOLIN 4 AMINE; N ISOPROPYL 2,7,9 TRIMETHYLOXAZOLO[4, 5-C]QUINOLIN 4 AMINE; N ISOPROPYL 3,7,9 TRIMETHYLISOXAZOLO[4, 5-C]QUINOLIN 4 AMINE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; BECKMANN REARRANGEMENT; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; MICROWAVE RADIATION; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

EID: 58849084129     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1083197     Document Type: Article

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