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Volumn 55, Issue 3, 2009, Pages 533-542

The Evolving Role of Oestrogens and Their Receptors in the Development and Progression of Prostate Cancer

Author keywords

HGPIN; Oestrogen receptor alpha and beta; Oestrogens; Phytoestrogens; Progesterone receptor; Prostate cancer; TMPRSS2 ERG

Indexed keywords

3 INDOLEMETHANOL; BIOLOGICAL MARKER; DUTASTERIDE; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FINASTERIDE; FULVESTRANT; GENISTEIN; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PHYTOESTROGEN; PLACEBO; RALOXIFENE; RESVERATROL; STEROID 5ALPHA REDUCTASE INHIBITOR; TESTOSTERONE; TOREMIFENE; TRIOXIFENE;

EID: 58849083630     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eururo.2008.10.035     Document Type: Review
Times cited : (156)

References (49)
  • 1
    • 0032973606 scopus 로고    scopus 로고
    • Estrogen receptor-beta: implications for the prostate gland
    • Chang W.Y., and Prins G.S. Estrogen receptor-beta: implications for the prostate gland. Prostate 40 (1999) 115-124
    • (1999) Prostate , vol.40 , pp. 115-124
    • Chang, W.Y.1    Prins, G.S.2
  • 2
    • 3843145374 scopus 로고    scopus 로고
    • Estrogens and anti-estrogens: key mediators of prostate carcinogenesis and new therapeutic candidates
    • Ho S.-M. Estrogens and anti-estrogens: key mediators of prostate carcinogenesis and new therapeutic candidates. J Cell Biochem 91 (2004) 491-503
    • (2004) J Cell Biochem , vol.91 , pp. 491-503
    • Ho, S.-M.1
  • 3
    • 35748985893 scopus 로고    scopus 로고
    • Estrogen action on the prostate gland: a critical mix of endocrine and paracrine signalling
    • Risbridger G.P., Ellem S.J., and McPherson S.J. Estrogen action on the prostate gland: a critical mix of endocrine and paracrine signalling. J Mol Endocrinol 39 (2007) 183-188
    • (2007) J Mol Endocrinol , vol.39 , pp. 183-188
    • Risbridger, G.P.1    Ellem, S.J.2    McPherson, S.J.3
  • 4
    • 42649083966 scopus 로고    scopus 로고
    • A potential paradox in prostate adenocarcinoma progression: oestrogen as the initiating driver
    • Singh P.B., Matanhelia S.S., and Martin F.L. A potential paradox in prostate adenocarcinoma progression: oestrogen as the initiating driver. Eur J Cancer 44 (2008) 928-936
    • (2008) Eur J Cancer , vol.44 , pp. 928-936
    • Singh, P.B.1    Matanhelia, S.S.2    Martin, F.L.3
  • 5
    • 0032778903 scopus 로고    scopus 로고
    • Estrogen receptor expression in prostate cancer and premalignant prostatic lesions
    • Bonkhoff H., Fixemer T., Hunsicker I., and Remberger K. Estrogen receptor expression in prostate cancer and premalignant prostatic lesions. Am J Pathol 155 (1999) 641-647
    • (1999) Am J Pathol , vol.155 , pp. 641-647
    • Bonkhoff, H.1    Fixemer, T.2    Hunsicker, I.3    Remberger, K.4
  • 6
    • 0035408472 scopus 로고    scopus 로고
    • Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma
    • Leav I., Lau K.M., Adams J.Y., et al. Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma. Am J Pathol 159 (2001) 79-92
    • (2001) Am J Pathol , vol.159 , pp. 79-92
    • Leav, I.1    Lau, K.M.2    Adams, J.Y.3
  • 7
    • 0037304336 scopus 로고    scopus 로고
    • Differential expression of the estrogen receptor beta (ER beta) in human prostate tissue, premalignant changes, and in primary, metastatic, and recurrent prostatic adenocarcinoma
    • Fixemer T., Remberger K., and Bonkhoff H. Differential expression of the estrogen receptor beta (ER beta) in human prostate tissue, premalignant changes, and in primary, metastatic, and recurrent prostatic adenocarcinoma. Prostate 54 (2003) 79-87
    • (2003) Prostate , vol.54 , pp. 79-87
    • Fixemer, T.1    Remberger, K.2    Bonkhoff, H.3
  • 8
    • 0030021453 scopus 로고    scopus 로고
    • Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: a stem cell model
    • Bonkhoff H., and Remberger K. Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: a stem cell model. Prostate 28 (1996) 98-106
    • (1996) Prostate , vol.28 , pp. 98-106
    • Bonkhoff, H.1    Remberger, K.2
  • 9
    • 34247104593 scopus 로고    scopus 로고
    • The role of estrogens in prostate carcinogenesis: a rationale for chemoprevention
    • Bosland M.C. The role of estrogens in prostate carcinogenesis: a rationale for chemoprevention. Rev Urol 7 Suppl 3 (2005) 4-10
    • (2005) Rev Urol , vol.7 , Issue.SUPPL. 3 , pp. 4-10
    • Bosland, M.C.1
  • 10
    • 43249092379 scopus 로고    scopus 로고
    • Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signalling
    • Ricke W.A., McPherson S.J., Bianco J.J., Cunha G.R., Wang Y., and Risbridger G.P. Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signalling. FASEB J 22 (2008) 1512-1520
    • (2008) FASEB J , vol.22 , pp. 1512-1520
    • Ricke, W.A.1    McPherson, S.J.2    Bianco, J.J.3    Cunha, G.R.4    Wang, Y.5    Risbridger, G.P.6
  • 12
    • 33746524463 scopus 로고    scopus 로고
    • Toremifene for the prevention of prostate cancer in men with high grade prostatic intraepithelial neoplasia: results of a double-blind, placebo controlled, phase IIB clinical trial
    • Price D., Stein B., Sieber P., et al. Toremifene for the prevention of prostate cancer in men with high grade prostatic intraepithelial neoplasia: results of a double-blind, placebo controlled, phase IIB clinical trial. J Urol 176 (2006) 965-970
    • (2006) J Urol , vol.176 , pp. 965-970
    • Price, D.1    Stein, B.2    Sieber, P.3
  • 13
    • 34547867581 scopus 로고    scopus 로고
    • Drug therapies for eradicating high-grade prostatic intraepithelial neoplasia in the prevention of prostate cancer
    • Taneja S.S. Drug therapies for eradicating high-grade prostatic intraepithelial neoplasia in the prevention of prostate cancer. Rev Urol 7 Suppl 3 (2005) 19-29
    • (2005) Rev Urol , vol.7 , Issue.SUPPL. 3 , pp. 19-29
    • Taneja, S.S.1
  • 15
    • 25844442402 scopus 로고    scopus 로고
    • Opportunities for prevention of prostate cancer: genetics, chemoprevention, and dietary intervention
    • Klein E.A. Opportunities for prevention of prostate cancer: genetics, chemoprevention, and dietary intervention. Rev Urol 4 Suppl 5 (2002) 18-28
    • (2002) Rev Urol , vol.4 , Issue.SUPPL. 5 , pp. 18-28
    • Klein, E.A.1
  • 16
    • 0032839509 scopus 로고    scopus 로고
    • Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice
    • Zhou J.R., Gugger E.T., Tanaka T., Guo Y., Blackburn G.L., and Clinton S.K. Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice. J Nutr 129 (1999) 1628-1635
    • (1999) J Nutr , vol.129 , pp. 1628-1635
    • Zhou, J.R.1    Gugger, E.T.2    Tanaka, T.3    Guo, Y.4    Blackburn, G.L.5    Clinton, S.K.6
  • 17
    • 0033950969 scopus 로고    scopus 로고
    • Rye bran and soy protein delay growth and increase apoptosis of human LNCaP prostate adenocarcinoma in nude mice
    • Bylund A., Zhang J.X., Bergh A., et al. Rye bran and soy protein delay growth and increase apoptosis of human LNCaP prostate adenocarcinoma in nude mice. Prostate 42 (2000) 304-314
    • (2000) Prostate , vol.42 , pp. 304-314
    • Bylund, A.1    Zhang, J.X.2    Bergh, A.3
  • 18
    • 0035884610 scopus 로고    scopus 로고
    • Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP)
    • Mentor-Marcel R., Lamartiniere C.A., Eltoum I.E., Greenberg N.M., and Elgavish A. Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP). Cancer Res 61 (2001) 6777-6782
    • (2001) Cancer Res , vol.61 , pp. 6777-6782
    • Mentor-Marcel, R.1    Lamartiniere, C.A.2    Eltoum, I.E.3    Greenberg, N.M.4    Elgavish, A.5
  • 19
    • 0033763830 scopus 로고    scopus 로고
    • Low-dose genistein induces cyclin-dependent kinase inhibitors and G(1) cell-cycle arrest in human prostate cancer cells
    • Shen J.C., Klein R.D., Wei Q., et al. Low-dose genistein induces cyclin-dependent kinase inhibitors and G(1) cell-cycle arrest in human prostate cancer cells. Mol Carcinog 29 (2000) 92-102
    • (2000) Mol Carcinog , vol.29 , pp. 92-102
    • Shen, J.C.1    Klein, R.D.2    Wei, Q.3
  • 20
    • 0037081891 scopus 로고    scopus 로고
    • Dietary genistein down-regulates androgen and estrogen receptor expression in the rat prostate
    • Fritz W.A., Wang J., Eltoum I.E., and Lamartiniere C.A. Dietary genistein down-regulates androgen and estrogen receptor expression in the rat prostate. Mol Cell Endocrinol 186 (2002) 89-99
    • (2002) Mol Cell Endocrinol , vol.186 , pp. 89-99
    • Fritz, W.A.1    Wang, J.2    Eltoum, I.E.3    Lamartiniere, C.A.4
  • 21
    • 33947626040 scopus 로고    scopus 로고
    • Genistein chemoprevention of prostate cancer in TRAMP mice
    • Wang J., Eltoum I.E., and Lamartiniere C.A. Genistein chemoprevention of prostate cancer in TRAMP mice. J Carcinog 6 (2007) 3
    • (2007) J Carcinog , vol.6 , pp. 3
    • Wang, J.1    Eltoum, I.E.2    Lamartiniere, C.A.3
  • 22
    • 35848961688 scopus 로고    scopus 로고
    • The relevance of estrogen receptor-beta expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment
    • Stettner M., Kaulfuss S., Burfeind P., et al. The relevance of estrogen receptor-beta expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment. Mol Cancer Ther 6 (2007) 2626-2633
    • (2007) Mol Cancer Ther , vol.6 , pp. 2626-2633
    • Stettner, M.1    Kaulfuss, S.2    Burfeind, P.3
  • 23
    • 42549087663 scopus 로고    scopus 로고
    • Involvement of the estrogen receptor beta in genistein-induced expression of p21(waf1/cip1) in PC-3 prostate cancer cells
    • Matsumura K., Tanaka T., Kawashima H., and Nakatani T. Involvement of the estrogen receptor beta in genistein-induced expression of p21(waf1/cip1) in PC-3 prostate cancer cells. Anticancer Res 28 (2008) 709-714
    • (2008) Anticancer Res , vol.28 , pp. 709-714
    • Matsumura, K.1    Tanaka, T.2    Kawashima, H.3    Nakatani, T.4
  • 25
    • 33749158008 scopus 로고    scopus 로고
    • Dietary intake of phytoestrogens, estrogen receptor-beta polymorphisms and the risk of prostate cancer
    • Hedelin M., Bälter K.A., Chang E.T., et al. Dietary intake of phytoestrogens, estrogen receptor-beta polymorphisms and the risk of prostate cancer. Prostate 66 (2006) 1512-1520
    • (2006) Prostate , vol.66 , pp. 1512-1520
    • Hedelin, M.1    Bälter, K.A.2    Chang, E.T.3
  • 26
    • 0035450793 scopus 로고    scopus 로고
    • Progesterone receptor expression in human prostate cancer: correlation with tumor progression
    • Bonkhoff H., Fixemer T., Hunsicker I., and Remberger K. Progesterone receptor expression in human prostate cancer: correlation with tumor progression. Prostate 48 (2001) 285-291
    • (2001) Prostate , vol.48 , pp. 285-291
    • Bonkhoff, H.1    Fixemer, T.2    Hunsicker, I.3    Remberger, K.4
  • 28
    • 44949204525 scopus 로고    scopus 로고
    • Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer
    • Setlur S.R., Mertz K.D., Hoshida Y., et al. Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer. J Natl Cancer Inst 100 (2008) 815-825
    • (2008) J Natl Cancer Inst , vol.100 , pp. 815-825
    • Setlur, S.R.1    Mertz, K.D.2    Hoshida, Y.3
  • 29
    • 45549090259 scopus 로고    scopus 로고
    • Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer
    • Mehra R., Tomlines S., Yu J., et al. Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer. Cancer Res 68 (2008) 3584-3590
    • (2008) Cancer Res , vol.68 , pp. 3584-3590
    • Mehra, R.1    Tomlines, S.2    Yu, J.3
  • 30
    • 36048971082 scopus 로고    scopus 로고
    • Steroid hormones and carcinogenesis of the prostate: the role of estrogens
    • Ricke W., Wang Y., and Cunha G. Steroid hormones and carcinogenesis of the prostate: the role of estrogens. Differentiation 75 (2007) 871-882
    • (2007) Differentiation , vol.75 , pp. 871-882
    • Ricke, W.1    Wang, Y.2    Cunha, G.3
  • 31
    • 53349128527 scopus 로고    scopus 로고
    • Differential expression of genes related to androgen and estrogen metabolism in hereditary versus sporadic prostate cancer
    • Fromont G., Yacoub M., Valeri A., et al. Differential expression of genes related to androgen and estrogen metabolism in hereditary versus sporadic prostate cancer. Cancer Epidemiol Biomarkers Prev 17 (2008) 1505-1509
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 1505-1509
    • Fromont, G.1    Yacoub, M.2    Valeri, A.3
  • 32
    • 0029758865 scopus 로고    scopus 로고
    • Elevated estrogen receptor expression in human prostatic stromal cells by androgen ablation therapy
    • Kruithof-Dekker I.G., Têtu B., Janssen P.J., and Van der Kwast T.H. Elevated estrogen receptor expression in human prostatic stromal cells by androgen ablation therapy. J Urol 156 (1996) 1194-1197
    • (1996) J Urol , vol.156 , pp. 1194-1197
    • Kruithof-Dekker, I.G.1    Têtu, B.2    Janssen, P.J.3    Van der Kwast, T.H.4
  • 33
    • 0035863389 scopus 로고    scopus 로고
    • Altered expression of androgen receptor in the malignant epithelium and adjacent stroma is associated with early relapse in prostate cancer
    • Henshall S.M., Quinn D.I., Lee C.S., et al. Altered expression of androgen receptor in the malignant epithelium and adjacent stroma is associated with early relapse in prostate cancer. Cancer Res 61 (2001) 423-427
    • (2001) Cancer Res , vol.61 , pp. 423-427
    • Henshall, S.M.1    Quinn, D.I.2    Lee, C.S.3
  • 34
    • 3042760475 scopus 로고    scopus 로고
    • High level of androgen receptor is associated with aggressive clinicopathologic features and decreased biochemical recurrence-free survival in prostate: cancer patients treated with radical prostatectomy
    • Li R., Wheeler T., Dai H., Frolov A., Thompson T., and Ayala G. High level of androgen receptor is associated with aggressive clinicopathologic features and decreased biochemical recurrence-free survival in prostate: cancer patients treated with radical prostatectomy. Am J Surg Pathol 28 (2004) 928-934
    • (2004) Am J Surg Pathol , vol.28 , pp. 928-934
    • Li, R.1    Wheeler, T.2    Dai, H.3    Frolov, A.4    Thompson, T.5    Ayala, G.6
  • 35
    • 1842612441 scopus 로고    scopus 로고
    • Molecular determinants of resistance to antiandrogen therapy
    • Chen C.D., Welsbie D.S., Tran C., et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med 10 (2004) 33-39
    • (2004) Nat Med , vol.10 , pp. 33-39
    • Chen, C.D.1    Welsbie, D.S.2    Tran, C.3
  • 36
    • 0028880540 scopus 로고
    • Raloxifene (LY156758) produces antimetastatic responses and extends survival in the PAIII rat prostatic adenocarcinoma model
    • Neubauer B.L., Best K.L., Counts D.F., et al. Raloxifene (LY156758) produces antimetastatic responses and extends survival in the PAIII rat prostatic adenocarcinoma model. Prostate 27 (1995) 220-229
    • (1995) Prostate , vol.27 , pp. 220-229
    • Neubauer, B.L.1    Best, K.L.2    Counts, D.F.3
  • 37
    • 0036645127 scopus 로고    scopus 로고
    • Raloxifene, a selective estrogen receptor modulator, induces apoptosis in androgen-responsive human prostate cancer cell line LNCaP through an androgen-independent pathway
    • Kim I.Y., Seong D.H., Kim B.C., et al. Raloxifene, a selective estrogen receptor modulator, induces apoptosis in androgen-responsive human prostate cancer cell line LNCaP through an androgen-independent pathway. Cancer Res 62 (2002) 3649-3653
    • (2002) Cancer Res , vol.62 , pp. 3649-3653
    • Kim, I.Y.1    Seong, D.H.2    Kim, B.C.3
  • 38
    • 0037105670 scopus 로고    scopus 로고
    • Raloxifene, a mixed estrogen agonist/antagonist, induces apoptosis in androgen-independent human prostate cancer cell lines
    • Kim I.Y., Kim B.C., Seong D.H., et al. Raloxifene, a mixed estrogen agonist/antagonist, induces apoptosis in androgen-independent human prostate cancer cell lines. Cancer Res 62 (2002) 5365-5369
    • (2002) Cancer Res , vol.62 , pp. 5365-5369
    • Kim, I.Y.1    Kim, B.C.2    Seong, D.H.3
  • 39
    • 0141507944 scopus 로고    scopus 로고
    • The selective estrogen receptor modulator trioxifene (LY133314) inhibits metastasis and extends survival in the PAIII rat prostatic carcinoma model
    • Neubauer B.L., McNulty A.M., Chedid M., et al. The selective estrogen receptor modulator trioxifene (LY133314) inhibits metastasis and extends survival in the PAIII rat prostatic carcinoma model. Cancer Res 63 (2003) 6056-6062
    • (2003) Cancer Res , vol.63 , pp. 6056-6062
    • Neubauer, B.L.1    McNulty, A.M.2    Chedid, M.3
  • 40
    • 33746102558 scopus 로고    scopus 로고
    • Fulvestrant (ICI 182,780) down-regulates androgen receptor expression and diminishes androgenic responses in LNCaP human prostate cancer cells
    • Bhattacharyya R.S., Krishnan A.V., Swami S., and Feldman D. Fulvestrant (ICI 182,780) down-regulates androgen receptor expression and diminishes androgenic responses in LNCaP human prostate cancer cells. Mol Cancer Ther 5 (2006) 1539-1549
    • (2006) Mol Cancer Ther , vol.5 , pp. 1539-1549
    • Bhattacharyya, R.S.1    Krishnan, A.V.2    Swami, S.3    Feldman, D.4
  • 41
    • 50949093030 scopus 로고    scopus 로고
    • Phase II study of fulvestrant (Faslodex) in castration resistant prostate cancer
    • Chadha M.K., Ashraf U., Lawrence D., et al. Phase II study of fulvestrant (Faslodex) in castration resistant prostate cancer. Prostate 68 (2008) 1461-1466
    • (2008) Prostate , vol.68 , pp. 1461-1466
    • Chadha, M.K.1    Ashraf, U.2    Lawrence, D.3
  • 42
    • 0036494569 scopus 로고    scopus 로고
    • Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model
    • Raghow S., Hooshdaran M.Z., Katiyar S., and Steiner M.S. Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model. Cancer Res 62 (2002) 1370-1376
    • (2002) Cancer Res , vol.62 , pp. 1370-1376
    • Raghow, S.1    Hooshdaran, M.Z.2    Katiyar, S.3    Steiner, M.S.4
  • 43
    • 36749091895 scopus 로고    scopus 로고
    • Toremifene increases bone mineral density in men receiving androgen deprivation therapy for prostate cancer: interim analysis of a multicenter phase 3 clinical study
    • Smith M.R., Malkowicz S.B., Chu F., et al. Toremifene increases bone mineral density in men receiving androgen deprivation therapy for prostate cancer: interim analysis of a multicenter phase 3 clinical study. J Urol 179 (2008) 152-155
    • (2008) J Urol , vol.179 , pp. 152-155
    • Smith, M.R.1    Malkowicz, S.B.2    Chu, F.3
  • 44
    • 42949158874 scopus 로고    scopus 로고
    • Toremifene improves lipid profiles in men receiving androgen-deprivation therapy for prostate cancer: interim analysis of a multicenter phase III study
    • Smith M.R., Malkowicz S.B., Chu F., et al. Toremifene improves lipid profiles in men receiving androgen-deprivation therapy for prostate cancer: interim analysis of a multicenter phase III study. J Clin Oncol 26 (2008) 1824-1829
    • (2008) J Clin Oncol , vol.26 , pp. 1824-1829
    • Smith, M.R.1    Malkowicz, S.B.2    Chu, F.3
  • 45
    • 51049098138 scopus 로고    scopus 로고
    • Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
    • Locke J.A., Guns E.S., Lubik A.A., et al. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res 68 (2008) 6407-6415
    • (2008) Cancer Res , vol.68 , pp. 6407-6415
    • Locke, J.A.1    Guns, E.S.2    Lubik, A.A.3
  • 46
    • 40849129897 scopus 로고    scopus 로고
    • Estrone sulfate (E1S), a prognosis marker for tumor aggressiveness in prostate cancer (PCa)
    • Giton F., de la Taille A., Allory Y., et al. Estrone sulfate (E1S), a prognosis marker for tumor aggressiveness in prostate cancer (PCa). J Steroid Biochem Mol Biol 109 (2008) 158-167
    • (2008) J Steroid Biochem Mol Biol , vol.109 , pp. 158-167
    • Giton, F.1    de la Taille, A.2    Allory, Y.3
  • 47
    • 0037029021 scopus 로고    scopus 로고
    • Methylation and inactivation of estrogen, progesterone, and androgen receptors in prostate cancer
    • Sasaki M., Tanaka Y., Perinchery G., et al. Methylation and inactivation of estrogen, progesterone, and androgen receptors in prostate cancer. J Natl Cancer Inst 94 (2002) 384-390
    • (2002) J Natl Cancer Inst , vol.94 , pp. 384-390
    • Sasaki, M.1    Tanaka, Y.2    Perinchery, G.3
  • 48
    • 0034126666 scopus 로고    scopus 로고
    • Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation
    • Lau K.M., LaSpina M., Long J., and Ho S.M. Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation. Cancer Res 60 (2000) 3175-3182
    • (2000) Cancer Res , vol.60 , pp. 3175-3182
    • Lau, K.M.1    LaSpina, M.2    Long, J.3    Ho, S.M.4
  • 49
    • 33749512368 scopus 로고    scopus 로고
    • Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signalling
    • Leung Y.K., Mak P., Hassan S., and Ho S.M. Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signalling. Proc Natl Acad Sci USA 103 (2006) 13163-13167
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13163-13167
    • Leung, Y.K.1    Mak, P.2    Hassan, S.3    Ho, S.M.4


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