-
1
-
-
0034077041
-
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich A., Schmitz Y., Farinas I., Choi-Lundberg D., Ho W.H., Castillo P.E., Shinsky N., Verdugo J.M., Armanini M., Ryan A., Hynes M., Phillips H., Sulzer D., and Rosenthal A. Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron 25 (2000) 239-252
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
Choi-Lundberg, D.4
Ho, W.H.5
Castillo, P.E.6
Shinsky, N.7
Verdugo, J.M.8
Armanini, M.9
Ryan, A.10
Hynes, M.11
Phillips, H.12
Sulzer, D.13
Rosenthal, A.14
-
2
-
-
0020837860
-
The role of dopamine in locomotor activity and learning
-
Beninger R.J. The role of dopamine in locomotor activity and learning. Brain Res. 287 (1983) 173-196
-
(1983)
Brain Res.
, vol.287
, pp. 173-196
-
-
Beninger, R.J.1
-
3
-
-
33750300797
-
Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein
-
Fleming S.M., Salcedo J., Hutson C.B., Rockenstein E., Masliah E., Levine M.S., and Chesselet M.F. Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein. Neuroscience 142 (2006) 1245-1253
-
(2006)
Neuroscience
, vol.142
, pp. 1245-1253
-
-
Fleming, S.M.1
Salcedo, J.2
Hutson, C.B.3
Rockenstein, E.4
Masliah, E.5
Levine, M.S.6
Chesselet, M.F.7
-
4
-
-
0025086433
-
MPTP-induced hypoactivity in mice: reversal by L-dopa
-
Fredriksson A., Plaznik A., Sundstrom E., Jonsson G., and Archer T. MPTP-induced hypoactivity in mice: reversal by L-dopa. Pharmacol. Toxicol 67 (1990) 295-301
-
(1990)
Pharmacol. Toxicol
, vol.67
, pp. 295-301
-
-
Fredriksson, A.1
Plaznik, A.2
Sundstrom, E.3
Jonsson, G.4
Archer, T.5
-
5
-
-
0037333642
-
Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice
-
Gomez-Isla T., Irizarry M.C., Mariash A., Cheung B., Soto O., Schrump S., Sondel J., Kotilinek L., Day J., Schwarzschild M.A., Cha J.H., Newell K., Miller D.W., Ueda K., Young A.B., Hyman B.T., and Ashe K.H. Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice. Neurobiol. Aging 24 (2003) 245-258
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 245-258
-
-
Gomez-Isla, T.1
Irizarry, M.C.2
Mariash, A.3
Cheung, B.4
Soto, O.5
Schrump, S.6
Sondel, J.7
Kotilinek, L.8
Day, J.9
Schwarzschild, M.A.10
Cha, J.H.11
Newell, K.12
Miller, D.W.13
Ueda, K.14
Young, A.B.15
Hyman, B.T.16
Ashe, K.H.17
-
6
-
-
0032103897
-
Characterization of enhanced behavioral responses to L-DOPA following repeated administration in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease
-
Henry B., Crossman A.R., and Brotchie J.M. Characterization of enhanced behavioral responses to L-DOPA following repeated administration in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease. Exp. Neurol 151 (1998) 334-342
-
(1998)
Exp. Neurol
, vol.151
, pp. 334-342
-
-
Henry, B.1
Crossman, A.R.2
Brotchie, J.M.3
-
7
-
-
0032500599
-
Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation
-
Jensen P.H., Nielsen M.S., Jakes R., Dotti C.G., and Goedert M. Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation. J. Biol. Chem. 273 (1998) 26292-26294
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26292-26294
-
-
Jensen, P.H.1
Nielsen, M.S.2
Jakes, R.3
Dotti, C.G.4
Goedert, M.5
-
8
-
-
0034660063
-
Dopamine-deficient mice are hypersensitive to dopamine receptor agonists
-
Kim D.S., Szczypka M.S., and Palmiter R.D. Dopamine-deficient mice are hypersensitive to dopamine receptor agonists. J. Neurosci 20 (2000) 4405-4413
-
(2000)
J. Neurosci
, vol.20
, pp. 4405-4413
-
-
Kim, D.S.1
Szczypka, M.S.2
Palmiter, R.D.3
-
9
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R., Kuhn W., Muller T., Woitalla D., Graeber M., Kosel S., Przuntek H., Epplen J.T., Schols L., and Riess O. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat. Genet. 18 (1998) 106-108
-
(1998)
Nat. Genet.
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
10
-
-
33747061265
-
A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats
-
Lee J., Di Marzo V., and Brotchie J.M. A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats. Neuropharmacology 51 (2006) 557-565
-
(2006)
Neuropharmacology
, vol.51
, pp. 557-565
-
-
Lee, J.1
Di Marzo, V.2
Brotchie, J.M.3
-
11
-
-
0036797552
-
Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease
-
Lotharius J., and Brundin P. Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease. Hum. Mol. Genet. 11 (2002) 2395-2407
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2395-2407
-
-
Lotharius, J.1
Brundin, P.2
-
12
-
-
0036884733
-
Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein
-
Lotharius J., and Brundin P. Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein. Nat. Rev. Neurosci 3 (2002) 932-942
-
(2002)
Nat. Rev. Neurosci
, vol.3
, pp. 932-942
-
-
Lotharius, J.1
Brundin, P.2
-
13
-
-
0028917869
-
Beneficial effects of co-administration of catechol-O-methyltransferase inhibitors and L-dihydroxyphenylalanine in rat models of depression
-
Mannistö P.T., Lang A., Rauhala P., and Vasar E. Beneficial effects of co-administration of catechol-O-methyltransferase inhibitors and L-dihydroxyphenylalanine in rat models of depression. Eur. J. Pharmacol 274 (1995) 229-233
-
(1995)
Eur. J. Pharmacol
, vol.274
, pp. 229-233
-
-
Mannistö, P.T.1
Lang, A.2
Rauhala, P.3
Vasar, E.4
-
14
-
-
0033054705
-
Role of high-affinity dopamine uptake and impulse activity in the appearance of extracellular dopamine in striatum after administration of exogenous L-DOPA: studies in intact and 6-hydroxydopamine-treated rats
-
Miller D.W., and Abercrombie E.D. Role of high-affinity dopamine uptake and impulse activity in the appearance of extracellular dopamine in striatum after administration of exogenous L-DOPA: studies in intact and 6-hydroxydopamine-treated rats. J. Neurochem 72 (1999) 1516-1522
-
(1999)
J. Neurochem
, vol.72
, pp. 1516-1522
-
-
Miller, D.W.1
Abercrombie, E.D.2
-
15
-
-
0036855635
-
Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies
-
Neumann M., Kahle P.J., Giasson B.I., Ozmen L., Borroni E., Spooren W., Muller V., Odoy S., Fujiwara H., Hasegawa M., Iwatsubo T., Trojanowski J.Q., Kretzschmar H.A., and Haass C. Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies. J. Clin. Invest 110 (2002) 1429-1439
-
(2002)
J. Clin. Invest
, vol.110
, pp. 1429-1439
-
-
Neumann, M.1
Kahle, P.J.2
Giasson, B.I.3
Ozmen, L.4
Borroni, E.5
Spooren, W.6
Muller, V.7
Odoy, S.8
Fujiwara, H.9
Hasegawa, M.10
Iwatsubo, T.11
Trojanowski, J.Q.12
Kretzschmar, H.A.13
Haass, C.14
-
17
-
-
0037092442
-
A role for alpha-synuclein in the regulation of dopamine biosynthesis
-
Perez R.G., Waymire J.C., Lin E., Liu J.J., Guo F.L., and Zigmond M.J. A role for alpha-synuclein in the regulation of dopamine biosynthesis. J. Neurosci 22 (2002) 3090-3099
-
(2002)
J. Neurosci
, vol.22
, pp. 3090-3099
-
-
Perez, R.G.1
Waymire, J.C.2
Lin, E.3
Liu, J.J.4
Guo, F.L.5
Zigmond, M.J.6
-
18
-
-
0036605566
-
Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters
-
Rockenstein E., Mallory M., Hashimoto M., Song D., Shults C.W., Lang I., and Masliah E. Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters. J. Neurosci. Res. 68 (2002) 568-578
-
(2002)
J. Neurosci. Res.
, vol.68
, pp. 568-578
-
-
Rockenstein, E.1
Mallory, M.2
Hashimoto, M.3
Song, D.4
Shults, C.W.5
Lang, I.6
Masliah, E.7
-
19
-
-
33750461646
-
Alpha-synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells
-
Tehranian R., Montoya S.E., Van Laar A.D., Hastings T.G., and Perez R.G. Alpha-synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells. J. Neurochem 99 (2006) 1188-1196
-
(2006)
J. Neurochem
, vol.99
, pp. 1188-1196
-
-
Tehranian, R.1
Montoya, S.E.2
Van Laar, A.D.3
Hastings, T.G.4
Perez, R.G.5
-
20
-
-
0029979753
-
Two simultaneously working storage pools of dopamine in mouse caudate and nucleus accumbens
-
Yavich L. Two simultaneously working storage pools of dopamine in mouse caudate and nucleus accumbens. Br. J. Pharmacol 119 (1996) 869-876
-
(1996)
Br. J. Pharmacol
, vol.119
, pp. 869-876
-
-
Yavich, L.1
-
21
-
-
0034617439
-
Dopamine release from pharmacologically distinct storage pools in rat striatum following stimulation at frequency of neuronal bursting
-
Yavich L., and MacDonald E. Dopamine release from pharmacologically distinct storage pools in rat striatum following stimulation at frequency of neuronal bursting. Brain Res. 870 (2000) 73-79
-
(2000)
Brain Res.
, vol.870
, pp. 73-79
-
-
Yavich, L.1
MacDonald, E.2
-
22
-
-
10944243102
-
Role of alpha-synuclein in presynaptic dopamine recruitment
-
Yavich L., Tanila H., Vepsäläinen S., and Jäkälä P. Role of alpha-synuclein in presynaptic dopamine recruitment. J. Neurosci 24 (2004) 11165-11170
-
(2004)
J. Neurosci
, vol.24
, pp. 11165-11170
-
-
Yavich, L.1
Tanila, H.2
Vepsäläinen, S.3
Jäkälä, P.4
-
23
-
-
26944501221
-
Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human α-synuclein
-
Yavich L., Oksman M., Tanila H., Kerokoski P., Hiltunen M., van Groen T., Puolivali J., Mannisto P.T., Garcia-Horsman A., and MacDonald E. Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human α-synuclein. Neurobiol. Dis 20 (2005) 303-313
-
(2005)
Neurobiol. Dis
, vol.20
, pp. 303-313
-
-
Yavich, L.1
Oksman, M.2
Tanila, H.3
Kerokoski, P.4
Hiltunen, M.5
van Groen, T.6
Puolivali, J.7
Mannisto, P.T.8
Garcia-Horsman, A.9
MacDonald, E.10
-
24
-
-
33750041624
-
Abnormal compartmentalization of norepinephrine in mouse dentate gyrus in alpha-synuclein knockout and A30P transgenic mice
-
Yavich L., Jakala P., and Tanila H. Abnormal compartmentalization of norepinephrine in mouse dentate gyrus in alpha-synuclein knockout and A30P transgenic mice. J. Neurochem 99 (2006) 724-732
-
(2006)
J. Neurochem
, vol.99
, pp. 724-732
-
-
Yavich, L.1
Jakala, P.2
Tanila, H.3
|