Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair

BMC Microbiology

Volumn 9, Issue , 2009, Pages

  Tibballs, Katrina L ^a   Ambur, Ole Herman ^b   Alfsnes, Kristian ^b   Homberset, Håvard ^a   Frye, Stephan A ^a,b   Davidsen, Tonje ^a   Tønjum, Tone ^a,b  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE;

ARTICLE; CHEMISTRY; DNA REPAIR; ENZYMOLOGY; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; NEISSERIA MENINGITIDIS; PROTEIN TERTIARY STRUCTURE;

BACTERIAL PROTEINS; DNA REPAIR; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; NEISSERIA MENINGITIDIS; PROTEIN STRUCTURE, TERTIARY;

EID: 58649123543     PISSN: 14712180     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-9-7     Document Type: Article

References (45)

1. Neisseria meningitidis: an overview of the carriage state. SP Yazdankhah DA Caugant, J Med Microbiol 2004 53 821 832 10.1099/jmm.0.45529-0 15314188
2. Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. DS Stephens B Greenwood P Brandtzaeg, Lancet 2007 369 2196 2210 10.1016/S0140-6736(07)61016-2 17604802
3. Pathogen DNA as target for host-generated oxidative stress: role for repair of bacterial DNA damage in Helicobacter pylori colonization. EJ O'Rourke C Chevalier AV Pinto JM Thiberge L Ielpi A Labigne JP Radicella, Proc Natl Acad Sci USA 2003 100 2789 2794 12601164 10.1073/pnas.0337641100
4. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions. KC Cheng DS Cahill H Kasai S Nishimura LA Loeb, J Biol Chem 1992 267 166 172 1730583
5. Imidazole open ring 7-methylguanine: an inhibitor of DNA synthesis. S Boiteux J Laval, Biochem Biophys Res Commun 1983 110 552 558 10.1016/0006-291X(83)91185-3 6340667
6. Mutagenicity, toxicity and repair of DNA base damage induced by oxidation. S Bjelland E Seeberg, Mutat Res 2003 531 37 80 14637246
7. 3'- and 5'-strand cleavage reactions catalyzed by the Fpg protein from Escherichia coli occur via successive beta- and delta-elimination mechanisms, respectively. M Bhagwat JA Gerlt, Biochemistry (Mosc) 1996 35 659 665 10.1021/bi9522662
8. The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine). ML Michaels JH Miller, J Bacteriol 1992 174 6321 6325 1328155
9. Genetic interactions of DNA repair pathways in the pathogen Neisseria meningitidis. T Davidsen HK Tuven M Bjoras EA Rodland T Tonjum, J Bacteriol 2007 189 5728 5737 17513474 10.1128/JB.00161-07
10. DNA repair profiles of disease-associated isolates of Neisseria meningitidis. T Davidsen EK Amundsen EA Rodland T Tonjum, FEMS Immunol Med Microbiol 2007 49 243 251 10.1111/j.1574-695X.2006.00195.x 17284282
11. Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. H Tettelin NJ Saunders J Heidelberg AC Jeffries KE Nelson JA Eisen KA Ketchum DW Hood JF Peden RJ Dodson, Science 2000 287 1809 1815 10.1126/science.287.5459.1809 10710307
12. Molecular cloning: a laboratory manual. J Sambrook DW Russell, Cold Springs Laboratory Press. Cold Spring Harbor, New York 2001
13. Recent improvements to the PROSITE database. N Hulo CJ Sigrist SV Le PS Langendijk-Genevaux L Bordoli A Gattiker CE De P Bucher A Bairoch, Nucleic Acids Res 2004 32 D134 D137 14681377 10.1093/nar/gkh044
14. The Pfam protein families database. A Bateman L Coin R Durbin RD Finn V Hollich S Griffiths-Jones A Khanna M Marshall S Moxon EL Sonnhammer, Nucleic Acids Res 2004 32 D138 D141 14681378 10.1093/nar/gkh121
15. Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491. J Parkhill M Achtman KD James SD Bentley C Churcher SR Klee G Morelli D Basham D Brown T Chillingworth, Nature 2000 404 502 506 10.1038/35006655 10761919
16. Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18. SD Bentley GS Vernikos LA Snyder C Churcher C Arrowsmith T Chillingworth A Cronin PH Davis NE Holroyd K Jagels, PLoS Genet 2007 3 e23 17305430 10.1371/journal.pgen.0030023
17. Characterization of ST-4821 complex, a unique Neisseria meningitidis clone. J Peng L Yang F Yang J Yang Y Yan H Nie X Zhang Z Xiong Y Jiang F Cheng, Genomics 2008 91 78 87 10.1016/j.ygeno.2007.10.004 18031983
18. JPred: a consensus secondary structure prediction server. JA Cuff ME Clamp AS Siddiqui M Finlay GJ Barton, Bioinformatics 1998 14 892 893 10.1093/bioinformatics/14.10.892 9927721
19. A novel method for accurate operon predictions in all sequenced prokaryotes. MN Price KH Huang EJ Alm AP Arkin, Nucleic Acids Res 2005 33 880 892 15701760 10.1093/nar/gki232
20. Base excision of oxidative purine and pyrimidine DNA damage in Saccharomyces cerevisiae by a DNA glycosylase with sequence similarity to endonuclease III from Escherichia coli. L Eide M Bjoras M Pirovano I Alseth KG Berdal E Seeberg, Proc Natl Acad Sci USA 1996 93 10735 10740 8855249 10.1073/pnas.93.20.10735
21. Two rotameric forms of open ring 7-methylguanine are present in alkylated polynucleotides. S Boiteux J Belleney BP Roques J Laval, Nucleic Acids Res 1984 12 5429 5439 6462910 10.1093/nar/12.13.5429
22. Natural transformation and phase variation modulation in Neisseria meningitidis. HL Alexander AR Richardson I Stojiljkovic, Mol Microbiol 2004 52 771 783 10.1111/j.1365-2958.2004.04013.x 15101983
23. Identification and arrangement of the DNA sequence recognized in specific transformation of Neisseria gonorrhoeae. SD Goodman JJ Scocca, Proc Natl Acad Sci USA 1988 85 6982 6986 3137581 10.1073/pnas.85.18.6982
24. New functional identity for the DNA uptake sequence in transformation and its presence in transcriptional terminators. OH Ambur SA Frye T Tonjum, J Bacteriol 2007 189 2077 2085 17194793 10.1128/JB.01408-06
25. Biased distribution of DNA uptake sequences towards genome maintenance genes. T Davidsen EA Rodland K Lagesen E Seeberg T Rognes T Tonjum, Nucleic Acids Res 2004 32 1050 1058 14960717 10.1093/nar/gkh255
26. Membrane glycerophospholipid biosynthesis in Neisseria meningitidis and Neisseria gonorrhoeae: identification, characterization, and mutagenesis of a lysophosphatidic acid acyltransferase. JS Swartley JT Balthazar J Coleman WM Shafer DS Stephens, Mol Microbiol 1995 18 401 412 10.1111/j.1365-2958.1995.mmi- 18030401.x 8748025
27. Co-transcription of a homologue of the formamidopyrimidine-DNA glycosylase (fpg) and lysophosphatidic acid acyltransferase (nlaA) in Neisseria meningitidis. JS Swartley DS Stephens, FEMS Microbiol Lett 1995 134 171 176 8586265
28. Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8. M Sugahara T Mikawa T Kumasaka M Yamamoto R Kato K Fukuyama Y Inoue S Kuramitsu, EMBO J 2000 19 3857 3869 10921868 10.1093/emboj/19.15.3857
29. Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA. L Serre JK Pereira de S Boiteux C Zelwer B Castaing, EMBO J 2002 21 2854 2865 12065399 10.1093/emboj/cdf304
30. Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA. R Gilboa DO Zharkov G Golan AS Fernandes SE Gerchman E Matz JH Kycia AP Grollman G Shoham, J Biol Chem 2002 277 19811 19816 10.1074/jbc.M202058200 11912217
31. Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM. JC Fromme GL Verdine, Nat Struct Biol 2002 9 544 552 12055620
32. Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites. S Boiteux TR O'Connor F Lederer A Gouyette J Laval, J Biol Chem 1990 265 3916 3922 1689309
33. Repair of oxidative DNA damage in gram-positive bacteria: the Lactococcus lactis Fpg protein. P Duwat OR de SD Ehrlich S Boiteux, Microbiology 1995 141 Pt 2 411 417 7704272
34. Substrate specificity of Deinococcus radiodurans Fpg protein. S Senturker C Bauche J Laval M Dizdaroglu, Biochemistry (Mosc) 1999 38 9435 9439 10.1021/bi990680m
35. 8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity. J Tchou H Kasai S Shibutani MH Chung J Laval AP Grollman S Nishimura, Proc Natl Acad Sci USA 1991 88 4690 4694 2052552 10.1073/pnas.88.11. 4690
36. A distinct role of formamidopyrimidine DNA glycosylase (MutM) in down-regulation of accumulation of G, C mutations and protection against oxidative stress in mycobacteria. R Jain P Kumar U Varshney, DNA Repair (Amst) 2007 6 1774 1785 10.1016/j.dnarep.2007.06.009 17698424
37. Adaptive evolution of highly mutable loci in pathogenic bacteria. ER Moxon PB Rainey MA Nowak RE Lenski, Curr Biol 1994 4 24 33 10.1016/S0960- 9822(00)00005-1 7922307
38. Mismatch repair and the regulation of phase variation in Neisseria meningitidis. AR Richardson I Stojiljkovic, Mol Microbiol 2001 40 645 655 10.1046/j.1365-2958.2001.02408.x 11359570
39. Mutator clones of Neisseria meningitidis in epidemic serogroup A disease. AR Richardson Z Yu T Popovic I Stojiljkovic, Proc Natl Acad Sci USA 2002 99 6103 6107 11983903 10.1073/pnas.092568699
40. Identification of Neisseria meningitidis genetic loci involved in the modulation of phase variation frequencies. HL Alexander AW Rasmussen I Stojiljkovic, Infect Immun 2004 72 6743 6747 15501815 10.1128/IAI.72.11.6743- 6747.2004
41. Involvement of genes of genome maintenance in the regulation of phase variation frequencies in Neisseria meningitidis. P Martin L Sun DW Hood ER Moxon, Microbiology 2004 150 3001 3012 10.1099/mic.0.27182-0 15347758
42. The FAPY-DNA glycosylase (Fpg) is required for survival of the cyanobacterium Synechococcus elongatus under high light irradiance. U Muhlenhoff, FEMS Microbiol Lett 2000 187 127 132 10856645
43. A novel role for Escherichia coli endonuclease VIII in prevention of spontaneous G - >T transversions. JO Blaisdell Z Hatahet SS Wallace, J Bacteriol 1999 181 6396 6402 10515930
44. Defenses against oxidative stress in Neisseria gonorrhoeae and Neisseria meningitidis: distinctive systems for different lifestyles. KL Seib HJ Tseng AG McEwan MA Apicella MP Jennings, J Infect Dis 2004 190 136 147 10.1086/421299 15195253
45. An outer membrane protein of Neisseria meningitidis group B responsible for serotype specificity. CE Frasch EC Gotschlich, J Exp Med 1974 140 87 104 4134571 10.1084/jem.140.1.87