Gabapentin versus tricyclic antidepressants for diabetic neuropathy and post-herpetic Neuralgia: Discrepancies between direct and indirect meta-analyses of randomized controlled trials

Journal of General Internal Medicine

Volumn 24, Issue 2, 2009, Pages 178-188

  Chou, Roger ^a,b,c   Carson, Susan ^a,b   Chan, Benjamin K S ^a,b  

^a Oregon Evidence based Practice Center   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c NONE   (United States)

Author keywords

Gabapentin; Meta analysis; Neuropathic pain; Tricyclic antidepressant

Indexed keywords

AMITRIPTYLINE; CLOMIPRAMINE; DESIPRAMINE; GABAPENTIN; IMIPRAMINE; NORTRIPTYLINE; PLACEBO; TRICYCLIC ANTIDEPRESSANT AGENT;

ANALGESIA; ARTICLE; ATAXIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DIABETIC NEUROPATHY; DIZZINESS; DRUG DOSE TITRATION; DRUG EFFECT; DRUG WITHDRAWAL; FATIGUE; HUMAN; LETHARGY; META ANALYSIS; POSTHERPETIC NEURALGIA; RANDOMIZED CONTROLLED TRIAL; SEDATION; SIDE EFFECT; SOMNOLENCE; SYSTEMATIC REVIEW; VERTIGO; XEROSTOMIA;

AMINES; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CYCLOHEXANECARBOXYLIC ACIDS; DIABETIC NEUROPATHIES; GAMMA-AMINOBUTYRIC ACID; HUMANS; NEURALGIA, POSTHERPETIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; UNITED STATES;

EID: 58649121268     PISSN: 08848734     EISSN: 15251497     Source Type: Journal    
DOI: 10.1007/s11606-008-0877-5     Document Type: Article

References (41)

1. RH Dworkin AB O'Connor M Backonja 2007 Pharmacologic management of neuropathic pain: Evidence-based recommendations Pain 132 237 251
2. I Gilron CPN Watson CM Cahill DE Moulin 2006 Neuropathic pain: a practical guide for the clinician CMAJ Can Med Assoc J 175 265 275
3. NB Finnerup M Otto HJ [tmp] McQuay TS Jensen SH Sindrup 2005 Algorithm for neuropathic pain treatment: an evidence based proposal Pain 118 289 305
4. SH Sindrup TS Jensen 1999 Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action Pain 83 389 400
5. MC Wong JW Chung TK Wong 2007 Effects of treatments for symptoms of painful diabetic neuropathy: systematic review BMJ 335 87
6. HC Bucher GH Guyatt LE Griffith SD Walter 1997 The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials J Clin Epidemiol 50 683 691
7. AM Glenny DG Altman F Song 2005 Indirect comparisons of competing interventions Health Technol Assess 9 1 134
8. R Chou R Fu LH Huffman PT Korthuis 2006 Initial highly-active antiretroviral therapy with a protease inhibitor versus a non-nucleoside reverse transcriptase inhibitor: discrepancies between direct and indirect analyses Lancet 368 1503 1515
9. F Song D Altman A-M Glenny J Deeks 2003 Validity of indirect comparison for estimating efficacy of competing interventions: empirical evidence from published meta-analyses BMJ 326 472
10. K Chandra N Shafiq P Pandhi S Gupta S Malhotra 2006 Gabapentin versus nortriptyline in post-herpetic neuralgia patients: a randomized, double-blind clinical trial-the GONIP Trial Int J Clin Pharmacol Therapeutics 44 358 363
11. C Dallocchio C Buffa P Mazzarello S Chiroli 2000 Gabapentin vs amitriptyline in painful diabetic neuropathy: an open-label pilot study J Pain Symptom Manage 20 280 285
12. CM Morello SG Leckband CP Stoner DF Moorhouse GA Sahagian 1999 Randomized double-blind study comparing the efficacy of gabapentin with amitriptyline on diabetic peripheral neuropathy pain Arch Internal Med 159 1931 1937
13. M Toma FA [tmp] McAlister L Bialy D Adams B Vandermeer PW Armstrong 2006 Transition from meeting abstract to full-length journal article for randomized controlled trials JAMA 295 1281 1287
14. DR Elbourne DG Altman JP Higgins F Curtin HV Worthington A Vail 2002 Meta-analyses involving cross-over trials: methodological issues Int J Epidemiol 31 140 149
15. K Hempenstall TJ Nurmikko RW Johnson RP A'Hern AS Rice 2005 Analgesic therapy in postherpetic neuralgia: a quantitative systematic review PLoS Med/Public Library Sci 2 e164
16. PJ Wiffen [tmp] McQuay JE Edward RA Moore 2005 Gabapentin for acute and chronic pain Cochrane Database Syst Rev 3 CD005452
17. Sutton AJ, Abrams KR, Jones DR, Sheldon TA, Song F. Methods for Meta-Analysis in Medical Research. West Sussex: John Wiley & Sons; 2000.
18. JPT Higgins SG Thompson 2002 Quantifying heterogeneity in a meta-analysis Stat Med 2 1539 1558
19. Team RDC. R: A Language and Environment for Statistical Computing. Vienna: R Foundation for Statistical Computing; 2006.
20. F Song 1999 Exploring heterogeneity in meta-analysis: Is the L'Abbe plot useful J Clin Epidemiol 52 725 730
21. M Egger G Smith M Schneider C Minder 1997 Bias in meta-analysis detected by a simple, graphical test BMJ 315 629 634
22. AJ Sutton SJ Duval RL Tweedie KR Abrams DR Jones 2000 Empirical assessment of effect of publication bias on meta-analyses BMJ 320 1574 1577
23. M Backonja A Beydoun KR Edwards 1998 Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial JAMA 280 1831 1836
24. I Gilron JM Bailey D Tu RR Holden DF Weaver RL Houlden 2005 Morphine, gabapentin, or their combination for neuropathic pain New England J Med 352 1324 1334
25. KC Gorson C Schott R Herman AH Ropper WM Rand 1999 Gabapentin in the treatment of painful diabetic neuropathy: a placebo controlled, double blind, crossover trial J Neurol, Neurosurgery & Psychiatry 66 251 252
26. AS Rice S Maton G Postherpetic Neuralgia Study 2001 Gabapentin in postherpetic neuralgia: a randomised, double blind, placebo controlled study Pain 94 215 224
27. M Rowbotham N Harden B Stacey P Bernstein L Magnus-Miller 1998 Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial JAMA 280 1837 1842
28. DA Simpson 2001 Gabapentin and venlafaxine for the treatment of painful diabetic neuropathy J Clin Neuromuscular Dis 3 53 62
29. R Kishore-Kumar MB Max SC Schafer 1990 Desipramine relieves postherpetic neuralgia Clin Pharmacol Therapeutics 47 3 305 312
30. B Kvinesdal J Molin A Froland LF Gram 1984 Imipramine treatment of painful diabetic neuropathy JAMA 251 1727 1730
31. MB Max M Culnane SC Schafer 1987 Amitriptyline relieves diabetic neuropathy pain in patients with normal or depressed mood Neurology 37 589 596
32. MB Max R Kishore-Kumar SC Schafer 1991 Efficacy of desipramine in painful diabetic neuropathy: a placebo-controlled trial Pain 45 3 9
33. MB Max SC Schafer M Culnane B Smoller R Dubner RH Gracely 1988 Amitriptyline, but not lorazepam, relieves postherpetic neuralgia Neurology 38 1427 1432
34. SN Raja JA Haythornthwaite M Pappagallo 2002 Opioids versus antidepressants in postherpetic neuralgia: a randomized, placebo-controlled trial Neurology 59 1015 1021
35. SH Sindrup B Ejlertsen A Froland EH Sindrup K Brosen LF Gram 1989 Imipramine treatment in diabetic neuropathy: relief of subjective symptoms without changes in peripheral and autonomic nerve function Eur J Clin Pharmacol 37 2 151 153
36. SH Sindrup LF Gram T Skjold E Grodum K Brosen H Beck-Nielsen 1990 Clomipramine vs desipramine vs placebo in the treatment of diabetic neuropathy symptoms. A double-blind cross-over study British J Clin Pharmacol 30 5 683 691
37. CP Watson RJ Evans K Reed H Merskey L Goldsmith J Warsh 1982 Amitriptyline versus placebo in postherpetic neuralgia Neurology 32 671 673
38. D Lathyris T Trikalinos JP Ioannidis 2007 Evidence from crossover trials: empirical evaluation and comparison against parallel arm trials Int J Epidemiol 36 422 430
39. I Ferreira-Gonzalez G Permanyer-Miralda JW Busse 2007 Methodologic discussions for using and interpreting composite endpoints are limited, but still identify major concerns J Clin Epidemiol 60 651 657
40. G Gartlehner RA Hansen D Nissman KN Lohr TS Carey 2006 A simple and valid tool distinguished efficacy from effectiveness studies J Clin Epidemiol 59 1040 1048
41. R Dworkin A O'Connor M Backonja 2007 Pharmacologic management of neuropathic pain: Evidence-based recommendations Pain 132 3 237 251