Mechanism of cytotoxic action of perfluorinated acids. I. Alteration in plasma membrane potential and intracellular pH level

Toxicology and Applied Pharmacology

Volumn 234, Issue 3, 2009, Pages 300-305

  Kleszczyński, Konrad ^a   Składanowski, Andrzej C ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Flow cytometry; HCT116 cells; Perfluorinated acids; pHi; Transmembrane potential

Indexed keywords

3,3' DIPENTYLOXACARBOCYANINE; FLUORESCEIN DIACETATE; FLUOROCARBON; PERFLUORO COMPOUND; UNCLASSIFIED DRUG;

ACIDIFICATION; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; CELL PH; CELL STRAIN HCT116; CHEMICAL STRUCTURE; COLON CARCINOMA; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DOSE RESPONSE; FLOW CYTOMETRY; FLUORESCENCE POLARIZATION IMMUNOASSAY; HUMAN; HUMAN CELL; HYDROPHOBICITY; INCUBATION TIME; MOLECULAR MECHANICS; MOLECULAR PROBE; PARAMETER;

CARBOCYANINES; CARCINOGENS, ENVIRONMENTAL; CELL MEMBRANE; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS; FLOW CYTOMETRY; FLUORESCEINS; FLUORESCENT DYES; FLUOROCARBONS; HCT116 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROPHOBICITY; MEMBRANE POTENTIALS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 58649089586     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.10.008     Document Type: Article

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