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Volumn 10, Issue 4, 2008, Pages 285-294

Glioblastoma multiforme

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; CARMUSTINE; CEDIRANIB; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; ETOPOSIDE; EVEROLIMUS; GEFITINIB; HYDROXYUREA; IMATINIB; IRINOTECAN; KETOCONAZOLE; LAPATINIB; MAMMALIAN TARGET OF RAPAMYCIN; PHENYTOIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; RETINOIC ACID; SORAFENIB; TEMOZOLOMIDE; TEMSIROLIMUS; THALIDOMIDE; VALPROIC ACID; VATALANIB;

EID: 58649089546     PISSN: 10928480     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11940-008-0031-z     Document Type: Review
Times cited : (8)

References (68)
  • 1
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • Louis DN, Ohgaki H, Wiestler OD, et al.: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007, 114:97-109.
    • (2007) Acta Neuropathol , vol.114 , pp. 97-109
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3
  • 2
    • 33847660578 scopus 로고    scopus 로고
    • Glioblastoma. Morphologic and molecular genetic diversity
    • Miller CR, Perry A: Glioblastoma. Morphologic and molecular genetic diversity. Arch Pathol Lab Med 2007, 131:397-406.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 397-406
    • Miller, C.R.1    Perry, A.2
  • 3
    • 58649100011 scopus 로고    scopus 로고
    • Overview of brain tumor epidemiology
    • In Edited by Newton HB, Jolesz FA. Amsterdam: Elsevier/Academic Press
    • Newton HB, Malkin MG: Overview of brain tumor epidemiology. In Handbook of Neuro-Oncology Neuroimaging. Edited by Newton HB, Jolesz FA. Amsterdam: Elsevier/Academic Press; 2007: 341-354.
    • (2007) Handbook of Neuro-Oncology Neuroimaging , pp. 341-354
    • Newton, H.B.1    Malkin, M.G.2
  • 4
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ, et al.: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005, 352:987-996.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3
  • 5
    • 46149093436 scopus 로고    scopus 로고
    • Is long-term survival in glioblastoma possible? Updated results of the EORTC/NCIC phase III randomized trial on radiotherapy (RT) and concomitant adjuvant temozolomide (TMZ) versus RT alone
    • [abstract]
    • Mirimanoff R, Mason W, Van den Bent M, et al.: Is long-term survival in glioblastoma possible? Updated results of the EORTC/NCIC phase III randomized trial on radiotherapy (RT) and concomitant adjuvant temozolomide (TMZ) versus RT alone [abstract]. Int J Radiat Oncol Biol Phys 2007, 69:S2.
    • (2007) Int J Radiat Oncol Biol Phys , vol.69
    • Mirimanoff, R.1    Mason, W.2    Van den Bent, M.3
  • 6
    • 35349023765 scopus 로고    scopus 로고
    • Novel therapies for malignant gliomas
    • Cavaliere R, Wen PY, Schiff D: Novel therapies for malignant gliomas. Neurol Clin 2007, 25:1041-1071.
    • (2007) Neurol Clin , vol.25 , pp. 1041-1071
    • Cavaliere, R.1    Wen, P.Y.2    Schiff, D.3
  • 7
    • 34248198326 scopus 로고    scopus 로고
    • Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide
    • Chinot OL, Barrié M, Fuentes S, et al.: Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide. J Clin Oncol 2007, 25:1470-1475.
    • (2007) J Clin Oncol , vol.25 , pp. 1470-1475
    • Chinot, O.L.1    Barrié, M.2    Fuentes, S.3
  • 8
    • 58649093710 scopus 로고    scopus 로고
    • Long-term therapy of brain tumors with temozolomide: Review of tolerability and efficacy in 47 patients
    • [abstract]
    • Newton HB, Dalton J, Figg G, et al.: Long-term therapy of brain tumors with temozolomide: Review of tolerability and efficacy in 47 patients [abstract]. Neuro Oncol 2007, 9:522-523.
    • (2007) Neuro Oncol , vol.9 , pp. 522-523
    • Newton, H.B.1    Dalton, J.2    Figg, G.3
  • 9
    • 33947200238 scopus 로고    scopus 로고
    • A pilot study of primary temozolomide chemotherapy and deferred radiotherapy in elderly patients with glioblastoma
    • Chamberlain MC, Chalmers L: A pilot study of primary temozolomide chemotherapy and deferred radiotherapy in elderly patients with glioblastoma. J Neurooncol 2007, 82:207-209.
    • (2007) J Neurooncol , vol.82 , pp. 207-209
    • Chamberlain, M.C.1    Chalmers, L.2
  • 10
    • 33846495120 scopus 로고    scopus 로고
    • A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme
    • Groves MD, Puduvalli VK, Chang SM, et al.: A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme. J Neurooncol 2007, 81:271-277.
    • (2007) J Neurooncol , vol.81 , pp. 271-277
    • Groves, M.D.1    Puduvalli, V.K.2    Chang, S.M.3
  • 11
    • 20044372154 scopus 로고    scopus 로고
    • MGMT gene silencing and benefit from temozolomide in glioblastoma
    • l outcome
    • Hegi ME, Diserens AC, Gorlia T, et al.: MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 2005, 352:997-1003. l outcome.
    • (2005) N Engl J Med , vol.352 , pp. 997-1003
    • Hegi, M.E.1    Diserens, A.C.2    Gorlia, T.3
  • 12
    • 4143084896 scopus 로고    scopus 로고
    • CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas
    • Paz MF, Yaya-Tur R, Rojas-Marcos I, et al.: CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas. Clin Cancer Res 2004, 10:4933-4938.
    • (2004) Clin Cancer Res , vol.10 , pp. 4933-4938
    • Paz, M.F.1    Yaya-Tur, R.2    Rojas-Marcos, I.3
  • 13
    • 12144291692 scopus 로고    scopus 로고
    • Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide
    • Hegi ME, Diserens AC, Godard S, et al.: Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. Clin Cancer Res 2004, 10:1871-1874.
    • (2004) Clin Cancer Res , vol.10 , pp. 1871-1874
    • Hegi, M.E.1    Diserens, A.C.2    Godard, S.3
  • 14
    • 34249053906 scopus 로고    scopus 로고
    • MGMT prognostic impact on glioblastoma is dependent on therapeutic modalities
    • Crinière E, Kaloshi G, Laigle-Donadey F, et al.: MGMT prognostic impact on glioblastoma is dependent on therapeutic modalities. J Neurooncol 2007, 83:173-179.
    • (2007) J Neurooncol , vol.83 , pp. 173-179
    • Crinière, E.1    Kaloshi, G.2    Laigle-Donadey, F.3
  • 15
    • 0037245929 scopus 로고    scopus 로고
    • Targeted molecular therapy of glioblastoma
    • Mischel PS, Cloughesy TF: Targeted molecular therapy of glioblastoma. Brain Pathol 2004, 13:52-61.
    • (2004) Brain Pathol , vol.13 , pp. 52-61
    • Mischel, P.S.1    Cloughesy, T.F.2
  • 16
    • 0242382624 scopus 로고    scopus 로고
    • Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors. Part 1: Growth factor and Ras signaling pathways
    • Newton HB: Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors. Part 1: Growth factor and Ras signaling pathways. Expert Rev Anticancer Ther 2003, 3:595-614.
    • (2003) Expert Rev Anticancer Ther , vol.3 , pp. 595-614
    • Newton, H.B.1
  • 17
    • 1142287357 scopus 로고    scopus 로고
    • Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis
    • Newton HB: Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis. Expert Rev Anticancer Ther 2004, 4:105-128.
    • (2004) Expert Rev Anticancer Ther , vol.4 , pp. 105-128
    • Newton, H.B.1
  • 18
    • 17544366279 scopus 로고    scopus 로고
    • Molecular neuro-oncology and the development of "targeted" therapeutic strategies for brain tumors. Part 5 - Apoptosis and cell cycle
    • Newton HB: Molecular neuro-oncology and the development of "targeted" therapeutic strategies for brain tumors. Part 5 - apoptosis and cell cycle. Expert Rev Anticancer Ther 2005, 5:355-378.
    • (2005) Expert Rev Anticancer Ther , vol.5 , pp. 355-378
    • Newton, H.B.1
  • 19
    • 34250803209 scopus 로고    scopus 로고
    • Molecularly targeted therapy for malignant gliomas
    • Sathornsumetee S, Reardon DA, Desjardins A, et al.: Molecularly targeted therapy for malignant gliomas. Cancer 2007, 110:13-24.
    • (2007) Cancer , vol.110 , pp. 13-24
    • Sathornsumetee, S.1    Reardon, D.A.2    Desjardins, A.3
  • 20
    • 36849040587 scopus 로고    scopus 로고
    • Small-molecule and antibody approaches to molecular chemotherapy of primary brain tumors
    • Newton HB: Small-molecule and antibody approaches to molecular chemotherapy of primary brain tumors. Curr Opin Investig Drugs 2007, 8:1009-1021.
    • (2007) Curr Opin Investig Drugs , vol.8 , pp. 1009-1021
    • Newton, H.B.1
  • 21
    • 36849062851 scopus 로고    scopus 로고
    • Phase II trial of high dose imatinib in recurrent glioblastoma multiforme (GBM) with platelet derived growth factor receptor (PDGFR) expression
    • [abstract] (June 20 Suppl)
    • Viola FS, Katz A, Arantes A, et al.: Phase II trial of high dose imatinib in recurrent glioblastoma multiforme (GBM) with platelet derived growth factor receptor (PDGFR) expression [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):89s.
    • (2007) J Clin Oncol , vol.25
    • Viola, F.S.1    Katz, A.2    Arantes, A.3
  • 22
    • 58649123313 scopus 로고    scopus 로고
    • Single center phase II trial analyzing the role of imatinib/hydroxyurea in patients with pretreated non-progressive glioblastoma (GBM) as maintenance treatment
    • [abstract] (June 20 Suppl)
    • Dresemann G, Hosius C, Nikolova Z, Letvak L: Single center phase II trial analyzing the role of imatinib/hydroxyurea in patients with pretreated non-progressive glioblastoma (GBM) as maintenance treatment [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):88s.
    • (2007) J Clin Oncol , vol.25
    • Dresemann, G.1    Hosius, C.2    Nikolova, Z.3    Letvak, L.4
  • 23
    • 53749108352 scopus 로고    scopus 로고
    • Imatinib plus hydroxyurea versus hydroxyurea monotherapy in progressive glioblastoma (GBM) - An international open label randomized phase III study (Ambrosia-Study)
    • [abstract]
    • Dresemann G, Rosenthal M, Höffken K, et al.: Imatinib plus hydroxyurea versus hydroxyurea monotherapy in progressive glioblastoma (GBM) - an international open label randomized phase III study (Ambrosia-Study) [abstract]. Neuro Oncol 2007, 9:519.
    • (2007) Neuro Oncol , vol.9 , pp. 519
    • Dresemann, G.1    Rosenthal, M.2    Höffken, K.3
  • 24
    • 36849013254 scopus 로고    scopus 로고
    • Phase I trial of imatinib mesylate, hydroxyurea, and vatalanib for patients with recurrent glioblastoma multiforme (GBM)
    • [abstract] (June 20 Suppl)
    • Sathornsumetee S, Rich JN, Vredenburgh JJ, et al.: Phase I trial of imatinib mesylate, hydroxyurea, and vatalanib for patients with recurrent glioblastoma multiforme (GBM) [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):81s.
    • (2007) J Clin Oncol , vol.25
    • Sathornsumetee, S.1    Rich, J.N.2    Vredenburgh, J.J.3
  • 25
    • 34247218483 scopus 로고    scopus 로고
    • Gefitinib in patients with progressive high-grade gliomas: A multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO)
    • Franceschi E, Cavallo G, Lonardi S, et al.: Gefitinib in patients with progressive high-grade gliomas: A multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). Br J Cancer 2007, 96:1047-1051.
    • (2007) Br J Cancer , vol.96 , pp. 1047-1051
    • Franceschi, E.1    Cavallo, G.2    Lonardi, S.3
  • 26
    • 58649089548 scopus 로고    scopus 로고
    • Randomized phase II trial of erlotinib (E) versus temozolomide (TMZ) or BCNU in recurrent glioblastoma multiforme (GBM): EORTC 26034
    • [abstract]
    • Van Den Bent MJ, Brandes AA, Rampling R, et al.: Randomized phase II trial of erlotinib (E) versus temozolomide (TMZ) or BCNU in recurrent glioblastoma multiforme (GBM): EORTC 26034 [abstract]. Neuro Oncol 2007, 9:522.
    • (2007) Neuro Oncol , vol.9 , pp. 522
    • Van Den Bent, M.J.1    Brandes, A.A.2    Rampling, R.3
  • 27
    • 36849007852 scopus 로고    scopus 로고
    • Phase II study of combination carboplatin and erlotinib in patients with recurrent glioblastoma multiforme
    • [abstract] (June 20 Suppl)
    • DeGroot JF, Gilbert MR, Hess KR, et al.: Phase II study of combination carboplatin and erlotinib in patients with recurrent glioblastoma multiforme [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):81s.
    • (2007) J Clin Oncol , vol.25
    • DeGroot, J.F.1    Gilbert, M.R.2    Hess, K.R.3
  • 28
    • 36849020698 scopus 로고    scopus 로고
    • Phase I study of erlotinib and CCI-779 (temsirolimus) for patients with recurrent malignant gliomas (MG) (NABTC 0402)
    • [abstract] (June 20 Suppl)
    • Robins HI, Wen PY, Chang SM, et al.: Phase I study of erlotinib and CCI-779 (temsirolimus) for patients with recurrent malignant gliomas (MG) (NABTC 0402) [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):89s.
    • (2007) J Clin Oncol , vol.25
    • Robins, H.I.1    Wen, P.Y.2    Chang, S.M.3
  • 29
    • 57149100275 scopus 로고    scopus 로고
    • Phase II study of tarceva plus temodar during and following radiotherapy in patients newly diagnosed with glioblastoma or gliosarcoma
    • [abstract]
    • Prados M, DeBoer R, Chang S, et al.: Phase II study of tarceva plus temodar during and following radiotherapy in patients newly diagnosed with glioblastoma or gliosarcoma [abstract]. Neuro Oncol 2007, 9:528.
    • (2007) Neuro Oncol , vol.9 , pp. 528
    • Prados, M.1    DeBoer, R.2    Chang, S.3
  • 30
    • 65349090491 scopus 로고    scopus 로고
    • Clinical and molecular-metabolic phase II trial of perifosine for recurrent/progressive malignant glioma
    • [abstract]
    • Lassman A, Holland E, DeAngelis L, et al.: Clinical and molecular-metabolic phase II trial of perifosine for recurrent/ progressive malignant glioma [abstract]. Neuro Oncol 2007, 9:518-519.
    • (2007) Neuro Oncol , vol.9 , pp. 518-519
    • Lassman, A.1    Holland, E.2    DeAngelis, L.3
  • 31
    • 34248372373 scopus 로고    scopus 로고
    • Rationale and clinical results of multi-target treatments in oncology
    • Sartore-Bianchi A, Ricotta R, Cerea G, et al.: Rationale and clinical results of multi-target treatments in oncology. Int J Biol Markers 2007, 22(Suppl 4):S77-S87.
    • (2007) Int J Biol Markers , vol.22 , Issue.SUPPL. 4
    • Sartore-Bianchi, A.1    Ricotta, R.2    Cerea, G.3
  • 32
    • 33749238553 scopus 로고    scopus 로고
    • Discovery and development of sorafenib: A multikinase inhibitor for treating cancer
    • Wilhelm S, Carter C, Lynch M, et al.: Discovery and development of sorafenib: A multikinase inhibitor for treating cancer. Nature Rev Drug Discov 2007, 5:835-844.
    • (2007) Nature Rev Drug Discov , vol.5 , pp. 835-844
    • Wilhelm, S.1    Carter, C.2    Lynch, M.3
  • 33
    • 36849058341 scopus 로고    scopus 로고
    • A phase I trial of sorafenib (BAY 43-9006) for patients with recurrent or progressive malignant glioma (NABTT 0401)
    • [abstract] (June 20 Suppl)
    • Nabors LB, Rosenfeld M, Chamberlain M, et al.: A phase I trial of sorafenib (BAY 43-9006) for patients with recurrent or progressive malignant glioma (NABTT 0401) [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):89s.
    • (2007) J Clin Oncol , vol.25
    • Nabors, L.B.1    Rosenfeld, M.2    Chamberlain, M.3
  • 34
    • 84975525035 scopus 로고
    • Clinical applications of research on angiogenesis
    • Folkman J: Clinical applications of research on angiogenesis. N Engl J Med 1995, 333:1757-1763.
    • (1995) N Engl J Med , vol.333 , pp. 1757-1763
    • Folkman, J.1
  • 35
    • 0034471796 scopus 로고    scopus 로고
    • Molecular mechanisms of tumor angiogenesis and tumor progression
    • Cavallaro U, Christofori G: Molecular mechanisms of tumor angiogenesis and tumor progression. J Neurooncol 2000, 50:63-70.
    • (2000) J Neurooncol , vol.50 , pp. 63-70
    • Cavallaro, U.1    Christofori, G.2
  • 36
    • 0034471876 scopus 로고    scopus 로고
    • Genes that regulate metastasis and angiogenesis
    • Webb CP, Vande Woude GF: Genes that regulate metastasis and angiogenesis. J Neurooncol 2000, 50:71-87.
    • (2000) J Neurooncol , vol.50 , pp. 71-87
    • Webb, C.P.1    Vande Woude, G.F.2
  • 37
    • 0032920232 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis in the brain
    • [review]
    • Plate KH: Mechanisms of angiogenesis in the brain [review]. J Neuropath Exp Neurol 1999, 58:313-320.
    • (1999) J Neuropath Exp Neurol , vol.58 , pp. 313-320
    • Plate, K.H.1
  • 38
    • 0032005359 scopus 로고    scopus 로고
    • Growth factor-mediated angiogenesis in the malignant progression of glial tumors: A review
    • Jensen RL: Growth factor-mediated angiogenesis in the malignant progression of glial tumors: A review. Surg Neurol 1998, 49:189-196.
    • (1998) Surg Neurol , vol.49 , pp. 189-196
    • Jensen, R.L.1
  • 39
    • 0034467330 scopus 로고    scopus 로고
    • Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs
    • Dunn IF, Heese O, Black PM: Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs. J Neurooncol 2000, 50:121-137.
    • (2000) J Neurooncol , vol.50 , pp. 121-137
    • Dunn, I.F.1    Heese, O.2    Black, P.M.3
  • 40
    • 0034213146 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1α in brain tumors. Association with angiogenesis, invasion, and progression
    • Zagzag D, Zhong H, Scalzitti JM, et al.: Expression of hypoxia-inducible factor 1α in brain tumors. Association with angiogenesis, invasion, and progression. Cancer 2000, 88:2606-2618.
    • (2000) Cancer , vol.88 , pp. 2606-2618
    • Zagzag, D.1    Zhong, H.2    Scalzitti, J.M.3
  • 41
    • 0034925041 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1
    • Jiang BH, Jiang G, Zheng JZ, et al.: Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1. Cell Growth Differ 2001, 12:363-369.
    • (2001) Cell Growth Differ , vol.12 , pp. 363-369
    • Jiang, B.H.1    Jiang, G.2    Zheng, J.Z.3
  • 43
    • 14644440555 scopus 로고    scopus 로고
    • Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
    • Hicklin DJ, Ellis LM: Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 2005, 23:1011-1027.
    • (2005) J Clin Oncol , vol.23 , pp. 1011-1027
    • Hicklin, D.J.1    Ellis, L.M.2
  • 44
    • 33645838598 scopus 로고    scopus 로고
    • Phase I study of antisense oligonucleotide against vascular endothelial growth factor: Decrease in plasma vascular endothelial growth factor with potential clinical efficacy
    • Levine AM, Tulpule A, Quinn DI, et al.: Phase I study of antisense oligonucleotide against vascular endothelial growth factor: Decrease in plasma vascular endothelial growth factor with potential clinical efficacy. J Clin Oncol 2006, 24:1712-1719.
    • (2006) J Clin Oncol , vol.24 , pp. 1712-1719
    • Levine, A.M.1    Tulpule, A.2    Quinn, D.I.3
  • 45
    • 33947531672 scopus 로고    scopus 로고
    • VEGF trap in combination with radiotherapy improves tumor control in u87 glioblastoma
    • Wachsberger PR, Burd R, Cardi C, et al.: VEGF trap in combination with radiotherapy improves tumor control in u87 glioblastoma. Int J Radiat Oncol Biol Phys 2007, 67:1526-1537.
    • (2007) Int J Radiat Oncol Biol Phys , vol.67 , pp. 1526-1537
    • Wachsberger, P.R.1    Burd, R.2    Cardi, C.3
  • 46
    • 33745738260 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: From the biology to the clinic
    • Ranieri G, Patruno R, Ruggieri E, et al.: Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: From the biology to the clinic. Curr Med Chem 2006, 13:1845-1857.
    • (2006) Curr Med Chem , vol.13 , pp. 1845-1857
    • Ranieri, G.1    Patruno, R.2    Ruggieri, E.3
  • 47
    • 33845961014 scopus 로고    scopus 로고
    • Bevacizumab: An angiogenesis inhibitor for the treatment of solid malignancies
    • Shih T,ALindley C: Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies. Clin Therap 2006, 28:1779-1802.
    • (2006) Clin Therap , vol.28 , pp. 1779-1802
    • Shih, T.1    Lindley, C.2
  • 48
    • 0035884609 scopus 로고    scopus 로고
    • Inhibition of intracranial glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2
    • Kunkel P, Ulbricht U, Bohlen P, et al.: Inhibition of intracranial glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2. Cancer Res 2001, 61:6624-6628.
    • (2001) Cancer Res , vol.61 , pp. 6624-6628
    • Kunkel, P.1    Ulbricht, U.2    Bohlen, P.3
  • 49
    • 0035688408 scopus 로고    scopus 로고
    • Monoclonal antibodies to vascular endothelial growth factor (VEGF) and the VEGF receptor, FLT-1, inhibit the growth of C6 glioma in a mouse xenograft
    • Stefanik DF, Fellows WK, Rizkalla LR, et al.: Monoclonal antibodies to vascular endothelial growth factor (VEGF) and the VEGF receptor, FLT-1, inhibit the growth of C6 glioma in a mouse xenograft. J Neurooncol 2001, 55:91-100.
    • (2001) J Neurooncol , vol.55 , pp. 91-100
    • Stefanik, D.F.1    Fellows, W.K.2    Rizkalla, L.R.3
  • 50
    • 32944482137 scopus 로고    scopus 로고
    • Bevacizumab and CPT-11 in the treatment of relapsed malignant glioma
    • [abstract 342]
    • Stark-Vance V: Bevacizumab and CPT-11 in the treatment of relapsed malignant glioma [abstract 342]. Neuro Oncol 2005, 7:369.
    • (2005) Neuro Oncol , vol.7 , pp. 369
    • Stark-Vance, V.1
  • 51
    • 33947191055 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
    • Vredenburgh JJ, Desjardins A, Herndon JE 2nd, et al.: Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin Cancer Res 2007, 13:1253-1259.
    • (2007) Clin Cancer Res , vol.13 , pp. 1253-1259
    • Vredenburgh, J.J.1    Desjardins, A.2    Herndon II, J.E.3
  • 52
    • 36849036553 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab and irinotecan in the treatment of malignant gliomas
    • [abstract] (June 20 Suppl)
    • Goli KJ, Desjardins A, Herndon JE, et al.: Phase II trial of bevacizumab and irinotecan in the treatment of malignant gliomas [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):75s.
    • (2007) J Clin Oncol , vol.25
    • Goli, K.J.1    Desjardins, A.2    Herndon, J.E.3
  • 53
    • 36049037819 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
    • Vredenburgh JJ, Desjardins A, Herndon JE, et al.: Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J Clin Oncol 2007, 25:4722-4729.
    • (2007) J Clin Oncol , vol.25 , pp. 4722-4729
    • Vredenburgh, J.J.1    Desjardins, A.2    Herndon, J.E.3
  • 54
    • 36849020237 scopus 로고    scopus 로고
    • Irinotecan and bevacizumab in progressive primary brain tumors: The Cleveland Clinic experience
    • [abstract] (June 20 Suppl)
    • Kang T, Jin T, Peereboom D: Irinotecan and bevacizumab in progressive primary brain tumors: The Cleveland Clinic experience [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):94s.
    • (2007) J Clin Oncol , vol.25
    • Kang, T.1    Jin, T.2    Peereboom, D.3
  • 55
    • 36849019200 scopus 로고    scopus 로고
    • Bevacizumab and irinotecan in patients with recurrent glioblastoma multiforme (GBM)
    • [abstract] (June 20 Suppl)
    • Raval S, Hwang S, Dorsett L: Bevacizumab and irinotecan in patients with recurrent glioblastoma multiforme (GBM) [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):94s.
    • (2007) J Clin Oncol , vol.25
    • Raval, S.1    Hwang, S.2    Dorsett, L.3
  • 56
    • 44449160698 scopus 로고    scopus 로고
    • Bevacizumab, a monoclonal antibody to the vascular endothelial growth factor (VEGF), and irinotecan for treatment of recurrent primary malignant brain tumors in adults
    • Hasselbalch B, Lassen U, Grunnet K, et al.: Bevacizumab, a monoclonal antibody to the vascular endothelial growth factor (VEGF), and irinotecan for treatment of recurrent primary malignant brain tumors in adults. Neuro Oncol 2007, 9:514.
    • (2007) Neuro Oncol , vol.9 , pp. 514
    • Hasselbalch, B.1    Lassen, U.2    Grunnet, K.3
  • 57
    • 36849015567 scopus 로고    scopus 로고
    • A phase II safety study of bevacizumab in patients with multiple recurrent or progressive malignant gliomas
    • [abstract] (June 20 Suppl)
    • Raizer JJ, Gallot L, Cohn R, et al.: A phase II safety study of bevacizumab in patients with multiple recurrent or progressive malignant gliomas [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):94s.
    • (2007) J Clin Oncol , vol.25
    • Raizer, J.J.1    Gallot, L.2    Cohn, R.3
  • 58
    • 33646675851 scopus 로고    scopus 로고
    • MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy
    • Pope WB, Lai A, Nghiemphu P, et al.: MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy. Neurology 2006, 66:1258-1260.
    • (2006) Neurology , vol.66 , pp. 1258-1260
    • Pope, W.B.1    Lai, A.2    Nghiemphu, P.3
  • 59
    • 36048955738 scopus 로고    scopus 로고
    • Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: A pilot study
    • Chen W, Delaloye S, Silverman DHS, et al.: Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: A pilot study. J Clin Oncol 2007, 25:4714-4721.
    • (2007) J Clin Oncol , vol.25 , pp. 4714-4721
    • Chen, W.1    Delaloye, S.2    Silverman, D.H.S.3
  • 60
    • 27944456516 scopus 로고    scopus 로고
    • Managing patients treated with bevacizumab combination therapy
    • Gordon MS, Cunningham D: Managing patients treated with bevacizumab combination therapy. Oncology 2005, 69(Suppl 3):25-33.
    • (2005) Oncology , vol.69 , Issue.SUPPL. 3 , pp. 25-33
    • Gordon, M.S.1    Cunningham, D.2
  • 61
    • 3543028023 scopus 로고    scopus 로고
    • PTK787/ZK2222584, an inhibitor of vascular endothelial growth factor tyrosine kinases, decreases glioma growth and vascularization
    • Goldbrunner RH, Bendszus M, Wood J, et al.: PTK787/ZK2222584, an inhibitor of vascular endothelial growth factor tyrosine kinases, decreases glioma growth and vascularization. Neurosurgery 2004, 55:426-432.
    • (2004) Neurosurgery , vol.55 , pp. 426-432
    • Goldbrunner, R.H.1    Bendszus, M.2    Wood, J.3
  • 62
    • 33947182049 scopus 로고    scopus 로고
    • Vatalanib: The clinical development of a tyrosine kinase inhibitor of angiogenesis in solid tumours
    • ScottTEN, Meinhardt G, Jacques C, et al.: Vatalanib: the clinical development of a tyrosine kinase inhibitor of angiogenesis in solid tumours. Expert Opin Investig Drugs 2007, 16:367-379.
    • (2007) Expert Opin Investig Drugs , vol.16 , pp. 367-379
    • Scott, E.N.1    Meinhardt, G.2    Jacques, C.3
  • 63
    • 34848847970 scopus 로고    scopus 로고
    • EORTC study 26041-22041: Phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with or without PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma-results of a phase I trial
    • [abstract 2026]. (June 20 Suppl)
    • Brandes AA, Stupp R, Hau P, et al.: EORTC study 26041-22041: Phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with or without PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma-results of a phase I trial [abstract 2026]. J Clin Oncol 2007, 25(June 20 Suppl):81s.
    • (2007) J Clin Oncol , vol.25
    • Brandes, A.A.1    Stupp, R.2    Hau, P.3
  • 64
    • 20144370978 scopus 로고    scopus 로고
    • AZD2171: A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer
    • WedAe SR, Kendrew J, Hennequin LE, et al.: AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res 2005, 65:4389-4400.
    • (2005) Cancer Res , vol.65 , pp. 4389-4400
    • Wedge, S.R.1    Kendrew, J.2    Hennequin, L.E.3
  • 65
    • 33846149645 scopus 로고    scopus 로고
    • AZD2171, a pan VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
    • Batchelor TT, Sorensen AG, de Tomaso E, et al.: AZD2171, a pan VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 2007, 11:83-95.
    • (2007) Cancer Cell , vol.11 , pp. 83-95
    • Batchelor, T.T.1    Sorensen, A.G.2    de Tomaso, E.3
  • 66
    • 36549065256 scopus 로고    scopus 로고
    • A phase II trial of AZD2171 (cediranib), an oral pan-VEGF receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma
    • [abstract] (June 20 Suppl)
    • Batchelor T, Sorensen AG, Ancukiewicz M, et al.: A phase II trial of AZD2171 (cediranib), an oral pan-VEGF receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma [abstract]. J Clin Oncol 2007, 25(June 20 Suppl):75s.
    • (2007) J Clin Oncol , vol.25
    • Batchelor, T.1    Sorensen, A.G.2    Ancukiewicz, M.3
  • 68
    • 35348964557 scopus 로고    scopus 로고
    • Advances in radiation therapy for brain tumors
    • Stieber VW, Mehta MP: Advances in radiation therapy for brain tumors. Neurol Clin 2007, 25:1005-1033.
    • (2007) Neurol Clin , vol.25 , pp. 1005-1033
    • Stieber, V.W.1    Mehta, M.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.