Ms identification of microcystin-LR chlorination by-products

Chemosphere

Volumn 74, Issue 6, 2009, Pages 832-839

  Merel, Sylvain ^a   LeBot, Barbara ^a   Clément, Michel ^a   Seux, René ^a   Thomas, Olivier ^a  

^a EHESP SCHOOL OF PUBLIC HEALTH   (France)

Author keywords

Cyanotoxin; Disinfection by chlorine; Drinking water treatment; LTQ Orbitrap; Mass spectrometry; Microcystin

Indexed keywords

CYANOTOXIN; DISINFECTION BY CHLORINE; DRINKING WATER TREATMENT; LTQ-ORBITRAP; MICROCYSTIN;

CHEMICALS REMOVAL (WATER TREATMENT); CHLORINATION; CHLORINE; CHLORINE COMPOUNDS; DISINFECTION; ELECTRIC REACTORS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERS; MASS SPECTROMETERS; MASS SPECTROMETRY; POTABLE WATER; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; TOXIC MATERIALS; WATER TREATMENT PLANTS;

WATER TREATMENT;

CHLORINE; DICHLORO DIHYDROXY MICROCYSTIN; DIHYDROXY MICROCYSTIN; MICROCYSTIN LR; MONOCHLORO DIHYDROXY MICROCYSTIN; MONOCHLORO HYDROXY MICROCYSTIN; MONOCHLORO MICROCYSTIN; TRICHLORO HYDROXY MICROCYSTIN; UNCLASSIFIED DRUG;

CHLORINATION; CONCENTRATION (COMPOSITION); DISINFECTION; DRINKING WATER; IDENTIFICATION METHOD; TOXIN; WATER TREATMENT;

ARTICLE; BACTERIUM IDENTIFICATION; CHEMICAL REACTION; CHLORINATION; ISOMER; MASS SPECTROMETER; MONITORING;

HALOGENATION; MASS SPECTROMETRY; MICROCYSTINS; STEREOISOMERISM; WATER PURIFICATION;

EID: 58549120155     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2008.10.024     Document Type: Article

References (38)

1. Acero J.L., Rodriguez E., and Meriluoto J. Kinetics of reactions between chlorine and the cyanobacterial toxins microcystins. Water Res. 39 (2005) 1628-1638
2. Alouini Z., and Seux R. Cinetiques et mecanismes de l'action oxydative de l'hypochlorite sur les acides [alpha]-amines lors de la desinfection des eaux. Kinetics and mechanisms of hypochlorite oxidation of [alpha]-amino acids at the time of water disinfection. Water Res. 21 (1987) 335-343
3. An J., and Carmichael W.W. Use of a colorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins. Toxicon 32 (1994) 1495-1507
4. Audi G., and Wapstra A.H. The 1995 update to the atomic mass evaluation. Nucl. Phys. A 595 (1995) 409-480
5. Azevedo S.M.F.O., Carmichael W.W., Jochimsen E.M., Rinehart K.L., Lau S., Shaw G.R., and Eaglesham G.K. Human intoxication by microcystins during renal dialysis treatment in Caruaru - Brazil. Toxicology 181-182 (2002) 441-446
6. Codd G.A., Morrison L.F., and Metcalf J.S. Cyanobacterial toxins: risk management for health protection. Toxicol. Appl. Pharm. 203 (2005) 264-272
7. Cong L., Huang B., Chen Q., Lu B., Zhang J., and Ren Y. Determination of trace amount of microcystins in water samples using liquid chromatography coupled with triple quadrupole mass spectrometry. Anal. Chim. Acta 569 (2006) 157-168
8. Dawson R.M. The toxicology of microcystins. Toxicon 36 (1998) 953-962
9. Diehnelt C.W., Peterman S.M., and Budde W.L. Liquid chromatography-tandem mass spectrometry and accurate m/z measurements of cyclic peptide cyanobacteria toxins. TRAC Trend. Anal. Chem. 24 (2005) 622-634
10. Dietrich D., and Hoeger S. Guidance values for microcystins in water and cyanobacterial supplement products (blue-green algal supplements): a reasonable or misguided approach?. Toxicol. Appl. Pharm. 203 (2005) 273-289
11. Edwards C., Beattie K.A., Scrimgeour C.M., and Codd G.A. Identification of anatoxin-A in benthic cyanobacteria (blue-green algae) and in associated dog poisonings at Loch Insh, Scotland. Toxicon 30 (1992) 1165-1175
12. Falconer I.R. Tumour promotion and liver injury caused by oral consumption of cyanobacteria. Environ. Toxic. Water 6 (1991) 177-218
13. Falconer I.R., Bartram J., Chorus I., Kuiper-Goodman T., Utkilen H., Burch M., and Codd G.A. Safe levels and safe practices. In: Chorus I., and Bartram J. (Eds). Toxic Cyanobacteria in Water: A Guide to Their Public Health Consequences, Monitoring and Management (1999), E&FN Spon, London, United Kingdom 155-178
14. Gupta N., Pant S.C., Vijayaraghavan R., and Rao P.V.L. Comparative toxicity evaluation of cyanobacterial cyclic peptide toxin microcystin variants (LR, RR, YR) in mice. Toxicology 188 (2003) 285-296
15. Harada K., Kondo F., and Lawton L. Laboratory analysis of cyanotoxins. In: Chorus I., and Bartram J. (Eds). Toxic Cyanobacteria in Water: A Guide to their Public Health Consequences, Monitoring and Management (1999), E&FN Spon, London, United Kingdom 369-405
16. Hitzfeld B.C., Hoeger S.J., and Dietrich D.R. Cyanobacterial toxins: removal during drinking water treatment, and human risk assessment. Environ. Health Persp. 108 (2000) 113-122
17. Ho L., Onstad G.D., von Gunten U., Rinck-Pfeiffer S., Craig K., and Newcombe G. Differences in the chlorine reactivity of four microcystin analogues. Water Res. 40 (2006) 1200-1209
18. Hureiki L., Croue J.P., and Legube B. Chlorination studies of free and combined amino acids. Water Res. 28 (1994) 2521-2531
19. Hyenstrand P., Metcalf J.S., Beattie K.A., and Codd G.A. Effects of adsorption to plastics and solvent conditions in the analysis of the cyanobacterial toxin microcystin-LR by high performance liquid chromatography. Water Res. 35 (2001) 3508-3511
20. Kondo F., Ikai Y., Oka H., Ishikawa N., Watanabe M.F., Watanabe M., Harada K.I., and Suzuki M. Separation and identification of microcystins in cyanobacteria by frit-fast atom bombardment liquid chromatography/mass spectrometry. Toxicon 30 (1992) 227-237
21. Kuiper-Goodman T., Falconer I., and Fitzgerald J. Human health aspects. In: Chorus I., and Bartram J. (Eds). Toxic Cyanobacteria in Water: A Guide to their Public Health Consequences, Monitoring and Management (1999), E&FN Spon, London, United Kingdom 113-153
22. Kull T.P.J., Backlund P.H., Karlsson K.M., and Meriluoto J. Oxidation of the cyanobacterial hepatotoxin microcystin-LR by chlorine dioxide: reaction kinetics, characterization, and toxicity of reaction products. Environ. Sci. Technol. 38 (2004) 6025-6031
23. Lawton L.A., and Robertson P.K.J. Physico-chemical treatment methods for the removal of microcystins (cyanobacterial hepatotoxins) from potable waters. Chem. Soc. Rev. 28 (1999) 217-224
24. MacKintosh C., Beattie K.A., Klumpp S., Cohen P., and Codd G.A. Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants. FEBS J. 264 (1990) 187-192
25. Makarov A., Denisov E., Lange O., and Horning S. Dynamic range of mass accuracy in LTQ orbitrap hybrid mass spectrometer. J. Am. Soc. Mass Spectr. 17 (2006) 977-982
26. Mez K., Beattie K.A., Codd G.A., Hanselmann K., Hauser B., Naegeli H., and Preisig H.R. Identification of a microcystin in benthic cyanobacteria linked to cattle deaths on alpine pastures in Switzerland. Eur. J. Phycol. 32 (1997) 111-117
27. Newcombe G., and Nicholson B. Water treatment options for dissolved cyanotoxins. J. Water Supply Res. T. 63 (2004) 227-239
28. Nicholson B.C., Rositano J., and Burch M.D. Destruction of cyanobacterial peptide hepatotoxins by chlorine and chloramine. Water Res. 28 (1994) 1297-1303
29. Nishiwaki-Matsushima R., Ohta T., Nishiwaki S., Suganuma M., Kohyama K., Ishikawa T., Carmichael W.W., and Fujiki H. Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR. J. Cancer Res. Clin. 118 (1992) 420-424
30. Peterman S.M., and Duczak N. Application of a linear ion trap/orbitrap mass spectrometer in metabolite characterization studies: examination of the human liver microsomal metabolism of the non-tricyclic anti-depressant nefazodone using data-dependent accurate mass measurements. J. Am. Soc. Mass Spectr. 17 (2006) 363-375
31. Pouët M.F., Baures E., Vaillant S., and Thomas O. Hidden isosbestic point(s) in ultraviolet spectra. Appl. Spectrosc. 58 (2004) 486-490
32. Pouria S., Andrade de A., Barbosa J., Cavalcanti R.L., Barreto V.T.S., Preiser W., Poon G.K., Neild G.H., and Codd G.A. Fatal microcystin intoxication in haemodialysis unit in Caruaru, Brazil. Lancet 352 9121 (1998) 21-26
33. Rodriguez E., Onstad G.D., Kull T.P.J., Metcalf J.S., Acero J.L., and von Gunten U. Oxidative elimination of cyanotoxins: comparison of ozone, chlorine, chlorine dioxide and permanganate. Water Res. 41 (2007) 3381-3393
34. Spinelli S., Gonzalez C., and Thomas O. UV spectra library. In: Thomas O., and Burgess C. (Eds). UV-Visible Spectrophotometry of Water and Wastewater (2007), Elsevier, Oxford, UK 267-356
35. Thomas O., and Cerda V. From spectra to qualitative and quantitative results. In: Thomas O., and Burgess C. (Eds). UV-Visible Spectrophotometry of Water and Wastewater (2007), Elsevier, Oxford, UK 21-46
36. Tsuji K., Watanuki T., Kondo F., Watanabe M.F., Nakazawa H., Suzuki M., Uchida H., and Harada K.I. Stability of microcystins from cyanobacteria - IV. Effect of chlorination on decomposition. Toxicon 35 (1997) 1033-1041
37. Xagoraraki I., Harrington G.W., Zulliger K., Zeier B., Krick W., Karner D.A., Standridge J.H., and Westrick J.A. Inactivation kinetics of the cyanobacterial toxin microcystin-LR by free chlorine. J. Environ. Eng.-ASCE 132 (2006) 818-823
38. Yuan M., Carmichael W.W., and Hilborn E.D. Microcystin analysis in human sera and liver from human fatalities in Caruaru, Brazil 1996. Toxicon 48 (2006) 627-640