Characterization of the murine Dfna5 promoter and regulatory regions

Gene

Volumn 432, Issue 1-2, 2009, Pages 82-90

  Vrijens, Karen ^a   Van Camp, Guy ^a   Van Laer, Lut ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Dfna5; Expression; Hearing loss; Methylation; Promoter

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DFNA5; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; COCHLEA AQUEDUCT; CONTROLLED STUDY; DNA FLANKING REGION; GENE IDENTIFICATION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SILENCER ELEMENT; TRANSCRIPTION INITIATION SITE;

5' FLANKING REGION; ANIMALS; BASE SEQUENCE; CELL LINE; COMPUTATIONAL BIOLOGY; DNA, ANTISENSE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; RECEPTORS, ESTROGEN; RNA, ANTISENSE; TRANSCRIPTION INITIATION SITE; TRANSFECTION;

MURINAE;

EID: 58549118908     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2008.11.017     Document Type: Article

References (39)

1. Ahituv N., et al. An ENU-induced mutation in AP-2alpha leads to middle ear and ocular defects in Doarad mice. Mamm. Genome 15 (2004) 424-432
2. Akino K., et al. Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer. Cancer Sci. 98 (2007) 88-95
3. Bischoff A.M., et al. A novel mutation identified in the DFNA5 gene in a Dutch family: a clinical and genetic evaluation. Audiol. Neurootol. 9 (2004) 34-46
4. Cheng J., et al. A novel DFNA5 mutation, IVS8 + 4 A > G, in the splice donor site of intron 8 causes late-onset non-syndromic hearing loss in a Chinese family. Clin. Genet. 72 (2007) 471-477
5. Delmaghani S., et al. Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy. Nat. Genet. 38 (2006) 770-778
6. Esteller M. CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene 21 (2002) 5427-5440
7. Faisst S., and Meyer S. Compilation of vertebrate-encoded transcription factors. Nucleic Acids Res. 20 (1992) 3-26
8. FitzGerald P.C., Shlyakhtenko A., Mir A.A., and Vinson C. Clustering of DNA sequences in human promoters. Genome Res. 14 (2004) 1562-1574
9. Gartner A., Collin L., and Lalli G. Nucleofection of primary neurons. Methods Enzymol. 406 (2006) 374-388
10. Glisson B.S., and Ross W.E. DNA topoisomerase II: a primer on the enzyme and its unique role as a multidrug target in cancer chemotherapy. Pharmacol. Ther. 32 (1987) 89-106
11. Gregan J., Van Laer L., Lieto L.D., Van Camp G., and Kearsey S.E. A yeast model for the study of human DFNA5, a gene mutated in nonsyndromic hearing impairment. Biochim. Biophys. Acta 1638 (2003) 179-186
12. Hale T.K., and Braithwaite A.W. The adenovirus oncoprotein E1a stimulates binding of transcription factor ETF to transcriptionally activate the p53 gene. J. Biol. Chem. 274 (1999) 23777-23786
13. Hashemzadeh Chaleshtori M., et al. Novel mutations in the pejvakin gene are associated with autosomal recessive non-syndromic hearing loss in Iranian families. Clin. Genet. 72 (2007) 261-263
14. Hilger-Eversheim K., Moser M., Schorle H., and Buettner R. Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control. Gene 260 (2000) 1-12
15. Hirose K., and Liberman M.C. Lateral wall histopathology and endocochlear potential in the noise-damaged mouse cochlea. J. Assoc. Res. Otolaryngol. 4 (2003) 339-352
16. Hohenstein K.A., Pyle A.D., Chern J.Y., Lock L.F., and Donovan P.J. Nucleofection Mediates High-efficiency Stable Gene Knockdown and Transgene Expression in Human Embryonic Stem Cells (2008), Stem cells, (Dayton, Ohio)
17. Kalinec F., Kalinec G., Boukhvalova M., and Kachar B. Establishment and characterization of conditionally immortalized organ of corti cell lines. Cell Biol. Int. 23 (1999) 175-184
18. Katayama S., et al. Antisense transcription in the mammalian transcriptome. Science (New York, NY 309 (2005) 1564-1566
19. Kim M.S., et al. Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma. Oncogene (2008)
20. Kim M.S., et al. Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer. Biochem. Biophys. Res. Commun. (2008)
21. Korneev S., and O'Shea M. Natural antisense RNAs in the nervous system. Rev. Neurosci. 16 (2005) 213-222
22. Kutach A.K., and Kadonaga J.T. The downstream promoter element DPE appears to be as widely used as the TATA box in Drosophila core promoters. Mol. Cell. Biol. 20 (2000) 4754-4764
23. Lage H., Helmbach H., Grottke C., Dietel M., and Schadendorf D. DFNA5 (ICERE-1) contributes to acquired etoposide resistance in melanoma cells. FEBS Lett. 494 (2001) 54-59
24. Lang H., Schulte B.A., Zhou D., Smythe N., Spicer S.S., and Schmiedt R.A. Nuclear factor kappaB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss. J. Neurosci. 26 (2006) 3541-3550
25. Lettice L.A., et al. A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. Hum. Mol. Genet. 12 (2003) 1725-1735
26. Masuda Y., et al. The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage. J. Hum. Genet. 51 (2006) 652-664
27. Mattson M.P. Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders. Neuromolecular Med. 3 (2003) 65-94
28. Schwander M., et al. A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function. J. Neurosci. 27 (2007) 2163-2175
29. Suzuki Y., et al. Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Res. 11 (2001) 677-684
30. Takai D., and Jones P.A. The CpG island searcher: a new WWW resource. In Silico Biol. 3 (2003) 235-240
31. Taylor A., Rogers M.J., Tosh D., and Coxon F.P. A novel method for efficient generation of transfected human osteoclasts. Calcif. Tissue Int. 80 (2007) 132-136
32. Thompson D.A., and Weigel R.J. Characterization of a gene that is inversely correlated with estrogen receptor expression (ICERE-1) in breast carcinomas. Eur. J. Biochem. 252 (1998) 169-177
33. Van Laer L., et al. Nonsyndromic hearing impairment is associated with a mutation in DFNA5. Nat. Genet. 20 (1998) 194-197
34. Van Laer L., et al. A novel DFNA5 mutation does not cause hearing loss in an Iranian family. J. Hum. Genet. 52 (2007) 549-552
35. Van Laer L., et al. DFNA5: hearing impairment exon instead of hearing impairment gene?. J. Med. Genet. 41 (2004) 401-406
36. White J.A., Burgess B.J., Hall R.D., and Nadol J.B. Pattern of degeneration of the spiral ganglion cell and its processes in the C57BL/6J mouse. Hear. Res. 141 (2000) 12-18
37. Won H.H., Kim M.J., Kim S., and Kim J.W. EnsemPro: an ensemble approach to predicting transcription start sites in human genomic DNA sequences. Genomics 91 (2008) 259-266
38. Yu C., Meng X., Zhang S., Zhao G., Hu L., and Kong X. A 3-nucleotide deletion in the polypyrimidine tract of intron 7 of the DFNA5 gene causes nonsyndromic hearing impairment in a Chinese family. Genomics 82 (2003) 575-579
39. Yu W., et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 451 (2008) 202-206