Single virus detection from the reactive shift of a whispering-gallery mode

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 52, 2008, Pages 20701-20704

  Vollmer, F ^a   Arnold, S ^b   Keng, D ^b  

^a HARVARD UNIVERSITY   (United States)

^b POLYTECHNIC UNIVERSITY   (United States)

Author keywords

Biosensor; Influenza; Optical resonance

Indexed keywords

MICROSPHERE; NANOPARTICLE; POLYSTYRENE;

ARTICLE; BIOSENSOR; CONTROLLED STUDY; ELECTRIC FIELD; ELECTROMAGNETIC FIELD; INFLUENZA VIRUS A; LIGHT SCATTERING; MATHEMATICAL MODEL; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; VIRION; VIRUS DETECTION; VIRUS PARTICLE;

INFLUENZA A VIRUS; LASERS; OPTICS AND PHOTONICS; SENSITIVITY AND SPECIFICITY; VIRION;

INFLUENZA A VIRUS;

EID: 58549114502     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0808988106     Document Type: Article

References (13)

1. P.W. Ewald (2002) In The Next Fifty Years, ed Brockman J (Vintage Books, New York), pp 289-301.
2. Arnold S, Khoshsima M, Teraoka I, Holler S, Vollmer F (2003) Shift of whispering gallery modes in microspheres by protein adsorption. Opt Lett 28:272-274.
3. Arnold S, Ramjit R, Keng D, Kolchenko V, Teraoka I (2008) Microparticle photophysics illuminates viral biosensing. Faraday Discuss 137:65-85.
4. Patolsky F, et al. (2004) Electrical detection of single viruses. PROC NATL ACAD SCI USA 101:14017-14022.
5. Ignatovich FV, Novotny L (2006) Real-time and background-free detection of nanoscale particles. Phys Rev Lett 96:0139011-0139014.
6. Vollmer F, et al. (2002) Protein detection by optical shift of a resonant microcavity. Appl Phys Lett 80:4057-4059.
7. Collot L, Lefevre-Seguin V, Brune M, Raimond JM, Haroche S (1993) Very high-Q whispering-gallery mode resonances observed on fused silica microspheres. Europhys Lett 25:327-334.
8. Lamb RA, Krug RM (2001) In Fundamental Virology, eds Knipe DM, Howley PM (Lippincott Williams & Wilkins, Philadelphia), pp 725-728.
9. Bresler SE, et al. (1975) Purification of influenza-viruses on wide-pore glass columns. Acta Virologica 19:190-196.
10. Vollmer F, Arnold S (2008) Whispering-gallery mode Biosensing: Label-free detection down to single molecules. Nat Methods 5:591-596.
11. Song BS, Noda S, Asano T, Akahane Y (2005) Ultra-high-Q photonic double-heterostructure nanocavity. Nat Mater 4:207-210.
12. Reimer CB, Baker RS, Newlin TE, Havens ML (1966) Influenza virus purification with the zonal ultracentrifuge. Science 3:1379-1381.
13. Armani AM, Kulkarni RP, Fraser SE, Flagan RC, Vahala KJ (2007) Label-free, single-molecule detection with optical microcavities. Science 317:783-787.