The effect of molecular weight, drug load, and charge of gelatin-MTX conjugates on growth inhibition of HL-60 leukemia cells

Pharmaceutical Research

Volumn 26, Issue 2, 2009, Pages 338-345

  Chen, Chao Sheng ^a   Ofner III, Clyde M ^a  

^a UNIVERSITY OF THE SCIENCES   (United States)

Author keywords

Charge; Drug load; HL 60 growth inhibition; Macromolecular drug conjugates; Molecular weight

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CYANAMIDE; GELATIN; METHOTREXATE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG CONJUGATION; DRUG RELEASE; ENZYME DEGRADATION; HUMAN; HUMAN CELL; IC 50; ISOELECTRIC FOCUSING; ISOELECTRIC POINT; MOLECULAR WEIGHT; PRIORITY JOURNAL; SPECTROPHOTOMETRY; TURBIDITY;

ANTIMETABOLITES, ANTINEOPLASTIC; CARBODIIMIDES; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG COMPOUNDING; ETHYLENEDIAMINES; GELATIN; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; ISOELECTRIC FOCUSING; LEUKEMIA; METHOTREXATE; MOLECULAR WEIGHT; NEPHELOMETRY AND TURBIDIMETRY; SPECTROPHOTOMETRY, ULTRAVIOLET; SURFACE PROPERTIES;

EID: 58549108961     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9746-5     Document Type: Article

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