Characterization and in vitro methotrexate release from methotrexate/gelatin conjugates of opposite conjugate bond polarity

Pharmaceutical Research

Volumn 17, Issue 10, 2000, Pages 1309-1315

  Bowman, Bill J ^a   Ofner, Clyde M ^a  

^a UNIVERSITY OF THE SCIENCES   (United States)

Author keywords

Conjugate fragments; Crosslinking; Gelatin methotrexate conjugates; Hydrolytic release from protein conjugates; Protein conjugate stability; Protein conjugation; Site specific conjugation

Indexed keywords

METHOTREXATE;

ARTICLE; CONTROLLED DRUG RELEASE; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG STABILITY; PRIORITY JOURNAL;

ANTIMETABOLITES, ANTINEOPLASTIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-LINKING REAGENTS; DRUG CARRIERS; DRUG STABILITY; GELATIN; KINETICS; METHOTREXATE; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0033634739     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026460023503     Document Type: Article

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