Organocatalyzed highly atom economic one pot synthesis of tetrahydropyridines as antimalarials

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 2, 2009, Pages 625-633

  Misra, Mridul ^a   Pandey, Swaroop Kumar ^a   Pandey, Vivek Parashar ^a   Pandey, Jyoti ^a   Tripathi, Renu ^a   Tripathi, Rama Pati ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Antimalarial activity; l Proline; Organocatalysis; Schizont maturation; Tetrahydropyridines; Trifluoroacetic acid

Indexed keywords

ANTIMALARIAL AGENT; METHYL 2,6 BIS(4 FLUOROPHENYL) 1 (4 METHOXYPHENYL) 4 (4 METHOXYPHENYLAMINO) 1,2,5,6 TETRAHYDROPYRIDINE 3 CARBOXYLATE; TETRAHYDROPYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG STRUCTURE; MALARIA; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ONE POT SYNTHESIS; PLASMODIUM FALCIPARUM; REACTION ANALYSIS; SCHIZONT; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; CATALYSIS; ERYTHROCYTES; HUMANS; MICROBIAL SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; PYRIDINES;

PLASMODIUM FALCIPARUM;

EID: 58549088118     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.11.062     Document Type: Article

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