Impact of very old age on the expression of cervical spinal cord cell markers in rats

Journal of Chemical Neuroanatomy

Volumn 37, Issue 2, 2009, Pages 98-104

  Fontana, Paula Andrea ^a   Barbeito, Claudio Gustavo ^a   Goya, Rodolfo Gustavo ^b   Gimeno, Eduardo Juan ^a   Portiansky, Enrique Leo ^a  

^a UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^b INSTITUTO DE INVESTIGACIONES BIOQUÍMICAS DE LA PLATA INIBIOLP   (Argentina)

Author keywords

Histochemistry; Intermediate filaments; Morphometry

Indexed keywords

CELL MARKER; NESTIN; VIMENTIN;

AGING; ANIMAL EXPERIMENT; ARTICLE; CERVICAL SPINAL CORD; CONTROLLED STUDY; EPENDYMA CELL; FEMALE; GRAY MATTER; HISTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT; MORPHOLOGY; NERVE FIBER; NEUROFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WHITE MATTER;

AGING; ANIMALS; BIOLOGICAL MARKERS; CERVICAL VERTEBRAE; EPENDYMA; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; INTERMEDIATE FILAMENTS; NERVE FIBERS, MYELINATED; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEURONS; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; S100 PROTEINS; SPINAL CORD; VIMENTIN;

EID: 58549085953     PISSN: 08910618     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchemneu.2008.11.001     Document Type: Article

References (26)

1. Alberts B., Johnson A., Lewis J., Raff M., Roberts K., and Walter P. The cytoskeleton. In: Alberts B., Johnson A., Lewis J., Raff M., Roberts K., and Walter P. (Eds). Molecular Biology of the Cell. 4th ed. (2002), Garland Science, USA 907-982
2. Al-Chalabi A., and Miller C.C. Neurofilaments and neurological disease. Bioessays 25 (2003) 346-355
3. Anderson K.D., Gunawan A., and Steward O. Spinal pathways involved in the control of forelimb motor function in rats. Exp. Neurol. 206 (2007) 318-331
4. Burek J.D. Pathology of Aging Rats (1978), CRC Press, Boca Ratón
5. Cairns N.J., Grossman M., Arnold S.E., Burn D.J., Jaros E., Perry R.H., Duyckaerts C., Stankoff B., Pillon B., Skullerud K., Cruz-Sanchez F.F., Bigio E.H., Mackenzie I.R., Gearing M., Juncos J.L., Glass J.D., Yokoo H., Nakazato Y., Mosaheb S., Thorpe J.R., Uryu K., Lee V.M., and Trojanowski J.Q. Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease. Neurology 63 (2004) 1376-1384
6. Chiasson K., Lahaie-Collins V., Bournival J., Delapierre B., Gélinas S., and Martinoli M.G. Oxidative stress and 17-alpha- and 17-beta-estradiol modulate neurofilaments differently. J. Mol. Neurosci. 30 (2006) 297-310
7. de Heredia F.P., Larque E., Del Puy Portillo M., Canteras M., Zamora S., and Garaulet M. Age-related changes in fatty acids from different adipose depots in rat and their association with adiposity and insulin. Nutrition 24 (2008) 1013-1022
8. Elder G.A., Friedrich Jr. V.L., Margita A., and Lazzarini R.A. Age-related atrophy of motor axons in mice deficient in the mid-sized neurofilament subunit. J. Cell Biol. 146 (1999) 181-192
9. Flynn J.R., and Bolton P.S. Measurement of the vertebral canal dimensions of the neck of the rat with a comparison to the human. Anat. Rec. 290 (2007) 893-899
10. Guerette D., Khan P.A., Savard P.E., and Vincent M. Molecular evolution of type VI intermediate filament proteins. BMC Evol. Biol. 7 (2007) 164 10.1186/1471-2148-7-164
11. Hilbig H., Bidmon H.J., Steingrüber S., Reinke H., and Dinse H.R. Enriched environmental conditions reverse age-dependent gliosis and losses of neurofilaments and extracellular matrix components but do not alter lipofuscin accumulation in the hindlimb area of the aging rat brain. J. Chem. Neuroanat. 23 (2002) 199-209
12. Ho C.L., and Liem R.K. Intermediate filaments in the nervous system: implications in cancer. Cancer Metast. Rev. 15 (1996) 483-497
13. Ivaska J., Pallari H.M., Nevo J., and Eriksson J. Novel functions of vimentin in cell adhesion, migration, and signaling. Exp. Cell Res. 313 (2007) 2050-2062
14. Jasmin L., and Ohara P.T. Recurrent paraplegia after remyelination of the spinal cord. J. Neurosci. Res. 77 (2004) 277-284
15. Kalous A., Osborne P.B., and Keast J.R. Acute and chronic changes in dorsal horn innervation by primary afferents and descending supraspinal pathways after spinal cord injury. J. Comp. Neurol. 504 (2007) 238-253
16. Kreplak L., and Fudge D. Biomechanical properties of intermediate filaments: from tissues to single filaments and back. Bioessays 29 (2007) 26-35
17. Liu C., Edwards S., Gong Q., Roberts N., and Blumhardt L.D. Three dimensional MRI estimates of brain and spinal cord atrophy in multiple sclerosis. J. Neurol. Neurosurg. Psychiatry 66 (1999) 323-630
18. Lozza, F.A., Chinchilla, L.A., Barbeito, C.G., Goya, R.G., Gimeno, E.J., Portiansky, E.L., in press. Changes in carbohydrate expression in the cervical spinal cord of rats during aging. Neuropathology, doi:10.1111/j.1440-1789.2008.00974.x.
19. Pekny M., and Wilhelmsson U. GFAP and astrocyte intermediate filaments. In: Abel Lajtha, and Ramon Lim (Eds). Handbook of Neurochemistry and Molecular Neurobiology. 3rd ed. (2007), Springer, USA 289-314
20. Portiansky E.L., Barbeito C.G., Goya R.G., Gimeno E.J., and Zuccolilli G.O. Morphometry of cervical segments grey matter in the male rat spinal cord. J. Neurosci. Methods 139 (2004) 217-229
21. Portiansky E.L., Barbeito C.G., Gimeno E.J., Zuccolilli G.O., and Goya R.G. Loss of NeuN immunoreactivity in rat spinal cord neurons during aging. Exp. Neurol. 202 (2006) 519-521
22. Sakaguchi T., Okada M., Kitamura T., and Kawasaki K. Reduced diameter and conduction velocity of myelinated fibers in the sciatic nerve of a neurofilament-deficient mutant quail. Neurosci. Lett. 153 (1993) 65-68
23. Shiozaki M., Yoshimura K., Shibata M., Koike M., Matsuura N., Uchiyama Y., and Gotow T. Morphological and biochemical signs of age-related neurodegenerative changes in Klotho mutant mice. Neuroscience 152 (2008) 924-941
24. Uchida A., Yorifuji H., Lee V.M., Kishimoto T., and Hisanaga S. Neurofilaments of aged rats: the strengthened interneurofilament interaction and the reduced amount of NF-M. J. Neurosci. Res. 58 (1999) 337-348
25. Vega-Avelaira D., Moss A., and Fitzgerald M. Age-related changes in the spinal cord microglial and astrocytic response profile to nerve injury. Brain Behav. Immun. 21 (2007) 617-623
26. Wuerker R.B., and Palay S.L. Neurofilaments and microtubules in anterior horn cells of the rat. Tissue Cell 1 (1969) 387-402