Protective effects of alanyl-glutamine on acute lung injury induced by lipopolysaccharide in rats

Journal of Central South University (Medical Sciences)

Volumn 33, Issue 12, 2008, Pages 1095-1100

  Liu, Jing Chen ^a   Wang, Hai Tang ^a   Wang, Wei ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Acute lung injury; Alanyl glutamine; Cell apoptosis; Cytokines; Sepsis

Indexed keywords

ALANYLGLUTAMINE; DIPEPTIDE; LIPOPOLYSACCHARIDE; PROTECTIVE AGENT;

ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; LUNG INJURY; RANDOMIZATION; RAT; SEPTIC SHOCK; WISTAR RAT;

ANIMALS; DIPEPTIDES; LIPOPOLYSACCHARIDES; LUNG INJURY; PROTECTIVE AGENTS; RANDOM ALLOCATION; RATS; RATS, WISTAR; SHOCK, SEPTIC;

EID: 58449135077     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Ware L B , Mattlmy M A. The acute respiratory distress syndrome[J]. N Engl J Med,2000,342(18):1334-1349.
2. Singleton KD, Serkova N, Beckey VE, et al. Glutamine attenuates lung Injury and improves survival after sepsis: Role of enhanced heat shock protein expression[J]. Crit Care Med,2005,33(6):1206-1213.
3. Lee W L, Downey G P. Neutrophil activation and acute lunginjury[J]. Curr Opin Crit Care,2001,7(1):1-7.
4. Abraham E. Neutrophils and acute lung injury[J]. Crit Care Med,2003,31(4 Suppl):195-199.
5. Melis G C, ter Wengel N, Boelens P G, et al. Glutamine: recent developments in research on the clinical sinificance of glutamine[J]. Curr Opin Clin Nutr Metab Care,2004,7(1):59-70.
6. Wischmeyer P E, Lynch J, Liedel J, et al. Glutamine administration reduces Gram-negative bacteremia in severely bumed patients: a prospective, randomized, double blind trial versus isonitrogenous control[J]. Crit Care Med,2001,29(11):2075-2080.
7. Hayashi Y, Sawa Y, Fukuyama N, et al. Preoperative glutamine administration induces heat-shock protein 70 expression and attenuates cardiopulmonary bypass-induce inflammatory response by regulating nitric oxide synthase activity[J]. Circulation,2002,106(20):2601-2607.